Monitoring conformational rearrangements in the substrate-binding site of a membrane transport protein by mass spectrometry

Journal of Biological Chemistry

Volumn 279, Issue 40, 2004, Pages 41858-41865

  Weinglass, Adam ^a   Whitelegge, Julian P ^a   Faull, Kym F ^a   Kaback, H Ronald ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CRYSTALLOGRAPHY; ESCHERICHIA COLI; HYDROGEN BONDS; IONIZATION; MASS SPECTROMETRY; SALTS; SUBSTRATES; SUGARS;

BINDING SITES; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; LACTOSE; SALT BRIDGES;

ENZYMES;

2,3 BUTANEDIONE; BENZALKONIUM CHLORIDE; CARRIER PROTEIN; COMPLEMENT COMPONENT C3; GUANIDINE DERIVATIVE; LIGAND; SUGAR;

ARTICLE; CARBOHYDRATE ANALYSIS; COVALENT BOND; ELECTROSPRAY MASS SPECTROMETRY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; MASS SPECTROMETRY; MEMBRANE TRANSPORT; MONITORING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 4744348289     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407555200     Document Type: Article

References (42)

1. Saier, M. H., Jr., Beatty, J. T., Goffeau, A., Harley, K. T., Heijne, W. H., Huang, S. C., Jack, D. L., Jahn, P. S., Lew, K., Liu, J., Pao, S. S., Paulsen, I. T., Tseng, T. T., and Virk, P. S. (1999) J. Mol. Microbiol. Biotechnol. 1, 257-279
2. Saier, M. H., Jr. (2000) Mol. Microbiol 35, 699-710
3. Konings, W. N., Kaback, H. R., and Lolkema, J. S. (1996) Handbook of Biological Physics: Transport Processes in Eukaryotic and Prokaryotic Organisms, Vol. II, Elsevier, Amsterdam
4. Foster, D. L., Boublik, M., and Kaback, H. R. (1983) J. Biol. Chem. 258, 31-34
5. Calamia, J., and Manoil, C. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 4937-4941
6. Kaback, H. R., and Wu, J. (1997) Q. Rev. Biophys. 30, 333-364
7. Abramson, J., Smirnova, I., Kasho, V., Verner, G., Kaback, H. R., and Iwata, S. (2003) Science 301, 610-615
8. Costello, M. J., Escaig, J., Matsushita, K., Viitanen, P. V., Menick, D. R., and Kaback, H. R. (1987) J. Biol. Chem. 262, 17072-17082
9. Sahin-Tóth, M., Lawrence, M. C., and Kaback, H. R. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5421-5425
10. Sandermann, H., Jr. (1977) Eur. J. Biochem. 80, 507-515
11. Olsen, S. G., and Brooker, R. J. (1989) J. Biol. Chem. 264, 15982-15987
12. Sahin-Tóth, M., Akhoon, K. M., Runner, J., and Kaback, H. R. (2000) Biochemistry 39, 5097-5103
13. Wu, J., and Kaback, H. R. (1994) Biochemistry 33, 12166-12171
14. Sahin-Tóth, M., Lawrence, M. C., Nishio, T., and Kaback, H. R. (2001) Biochemistry 43, 13015-13019
15. Sahin-Tóth, M., Gunawan, P., Lawrence, M. C., Toyokuni, T., and Kaback, H. R. (2002) Biochemistry 41, 13039-13045
16. Hirai, T., Heymann, J. A., Maloney, P. C., and Subramaniam, S. (2003) J. Bacteriol. 185, 1712-1718
17. Huang, Y., Lemieux, M. J., Song, J., Auer, M., and Wang, D. N. (2003) Science 301, 616-620
18. Frillingos, S., Ujwal, M. L., Sun, J., and Kaback, H. R. (1997) Protein Sci. 6, 431-437
19. Venkatesan, P., and Kaback, H. R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9802-9807
20. Sahin-Tóth, M., le Coutre, J., Kharabi, D., le Maire, G., Lee, J. C., and Kaback, H. R. (1999) Biochemistry 38, 813-819
21. Zhao, M., Zen, K. C., Hubbell, W. L., and Kaback, H. R. (1999) Biochemistry 38, 7407-7412
22. Wolin, C. D., and Kaback, H. R. (2000) Biochemistry 39, 6130-6135
23. Guan, L., Hu, Y., and Kaback, H. R. (2003) Biochemistry 42, 1377-1382
24. Vazquez-Ibar, J. L., Guan, L., Svrakic, M., and Kaback, H. R. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 12706-12711
25. Ujwal, M. L., Sahin-Tóth, M., Persson, B., and Kaback, H. R. (1994) Mol. Membr. Biol. 11, 9-16
26. Franco, P. J., and Brooker, R. J. (1994) J. Biol. Chem. 269, 7379-7386
27. He, M., and Kaback, H. R. (1997) Biochemistry 36, 13688-13692
28. Sahin-Tóth, M., Karlin, A., and Kaback, H. R. (2000) Proc. Natl. Acad. Sd. U. S. A. 97, 10729-10732
29. Weinglass, A. B., Sondej, M., and Kaback, H. R. (2002) J. Mol. Biol. 315, 561-571
30. Weinglass, A. B., Whitelegge, J. P., Hu, Y., Verner, G. E., Faull, K. F., and Kaback, H. R. (2003) EMBO J. 22, 1467-1477
31. Lundblad, R. L. (1995) in Techniques in Protein Modification, Vol. 1, pp. 187-208, CRC Press, New York
32. Kaback, H. R. (1974) Methods Enzymol. 31, 698-709
33. Wessel, D., and Flügge, U. I. (1984) Anal. Biochem. 138, 141-143
34. Witkop, B. (1961) Adv. Protein Chem. 16, 221-321
35. Whitelegge, J. P., Jewess, P., Pickering, M. G., Gerrish, C., Camilleri, P., and Bowyer, J. R. (1992) Eur. J. Biochem. 207, 1077-1084
36. Whitelegge, J. P., Gundersen, C. B., and Faull, K. F. (1998) Protein Sci. 7, 1423-1430
37. Biemann, K. (1990) Methods Enzymol. 193, 886-887
38. Roepstorff, P., and Fohlman, J. (1984) Biomed. Mass Spectrom. 11, 601
39. Frillingos, S., Sahin-Toth, M., Wu, J., and Kaback, H. R. (1998) FASEB J. 12, 1281-1299
40. Smirnova, I. N., and Kaback, H. R. (2003) Biochemistry 42, 3025-3031
41. Frillingos, S., Gonzalez, A., and Kaback, H. R. (1997) Biochemistry 36, 14284-14290
42. Zhao, M., Zen, K.-C., Hernandez-Borrell, J., Altenbach, C., Hubbell, W. L., and Kaback, H. R. (1999) Biochemistry 38, 15970-15977