Overexpression of PGC-1β improves insulin sensitivity and mitochondrial function in 3T3-L1 adipocytes

Molecular and Cellular Biochemistry

Volumn 353, Issue 1-2, 2011, Pages 215-223

  Gao, Chun Lin ^a   Liu, Guang Ling ^a   Liu, Shi ^c   Chen, Xiao Hui ^b   Ji, Chen Bo ^b   Zhang, Chun Mei ^b   Xia, Zheng Kun ^a   Guo, Xi Rong ^b  

^a NANJING GENERAL HOSPITAL OF NANJING MILITARY COMMAND   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c Huai'an Maternal and Child Health Care Center   (China)

Author keywords

3T3 L1 adipocyte; Insulin resistance; Mitochondrial function; Mitochondrial membrane potential; PGC 1 ; Reactive oxygen species

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE 2; ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; HEXOKINASE; HEXOKINASE 2; MESSENGER RNA; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN;

ADIPOCYTE; ARTICLE; BIOGENESIS; CELL FUNCTION; CELL STRAIN 3T3; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GLUCOSE TRANSPORT; INSULIN SENSITIVITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

3T3-L1 CELLS; ACETYL-COA CARBOXYLASE; ADENOSINE TRIPHOSPHATE; ADIPOCYTES; ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION; GLUCOSE; HEXOKINASE; HYPOGLYCEMIC AGENTS; INSULIN; ION CHANNELS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATORS;

EID: 79959276725     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0789-2     Document Type: Article

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