T16189C mitochondrial DNA variant is associated with metabolic syndrome in Caucasian subjects

Nutrition

Volumn 27, Issue 7-8, 2011, Pages 773-777

  Palmieri, Vincenzo Ostilio ^a   De Rasmo, Domenico ^a   Signorile, Anna ^a   Sardanelli, Anna Maria ^a   Grattagliano, Ignazio ^a   Minerva, Francesco ^a   Cardinale, Giovanna ^a   Portincasa, Piero ^a   Papa, Sergio ^a,b   Palasciano, Giuseppe ^a  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

Author keywords

Arterial hypertension; Insulin resistance; Metabolic syndrome; Mitochondrial DNA variant; Overweight; T16189C

Indexed keywords

CYTOSINE; MITOCHONDRIAL DNA; THYMINE;

ADULT; ARTICLE; BODY MASS; CAUCASIAN; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; HOMEOSTASIS; HUMAN; HYPERTENSION; INTRAABDOMINAL FAT; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PHENOTYPE; PRIORITY JOURNAL; WAIST CIRCUMFERENCE;

ABDOMINAL FAT; ADULT; BODY MASS INDEX; DNA, MITOCHONDRIAL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC VARIATION; HUMANS; HYPERTENSION; INSULIN RESISTANCE; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MUTATION; WAIST CIRCUMFERENCE;

EID: 79959269327     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2010.08.016     Document Type: Article

References (35)

1. Grattagliano I., Palmieri V.O., Portincasa P., Moschetta A., Palasciano G. Oxidative stress-induced risk factors associated with metabolic syndrome: a unifying hypothesis. J Nutr Biochem 2008, 19:491-504.
2. Isomaa B., Henricsson M., Almgren P., Tuomi T., Taskinen M.R., Groop L. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001, 24:683-689.
3. McNeill A.M., Rosamond W.D., Girman C.J., Golden S.H., Schmidt M.I., East H.E., Ballantyne C.M., Heiss G. The metabolic syndrome and 11- year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care 2005, 28:385-390.
4. Alberti K.G., Zimmet P., Shaw J. The metabolic syndrome: a new worldwide definition. Lancet 2005, 366:1059-1062. IDF Epidemiology Task Force Consensus Group.
5. Acheson K.J. Carbohydrate for weight and metabolic control: where do we stand?. Nutrition 2010, 26:141-145.
6. Ramel A., Martinez J.A., Kiely M., Bandarra N.M., Thorsdottir I. Moderate consumption of fatty fish reduces diastolic blood pressure in overweight and obese European young adults during energy restriction. Nutrition 2010, 26:168-174.
7. Ordovas J. Nutrigenetics, plasma lipids and cardiovascular risk. J Am Diet Assoc 2006, 106:1074-1081.
8. Poulton J., Luan J., Macaulay V., Hennings S., Mitchell J., Wareham N.J. Type 2 diabetes is associated with a common mitochondrial variant: evidence from a population-based case-control study. Hum Mol Genet 2002, 11:1581-1583.
9. Wilson F.H., Hariri A., Farhi A., Zhao H., Petersen K.F., Toka H.R., et al. A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science 2004, 306:1190-1194.
10. Casteels K., Ong K., Phillips D., Bendall H., Pembrey M. Mitochondrial 16189 variant, thinness at birth, and type-2 diabetes. ALSPAC study team. Avon Longitudinal Study of Pregnancy and Childhood. Lancet 1999, 353:1499-1500.
11. Parker E., Phillips D.I.W., Cockington R.A., Cull C., Poulton J. A common mitochondrial DNA variant is associated with thinness in mothers and their 20-yr-old offspring. Am J Physiol Endrocrinol Metab 2005, 289:E1110-E1114.
12. Poulton J., Scott Brown M., Cooper A., Marchington D.R., Phillips D.I.W. A common mitochondrial DNA variant is associated with insulin resistance in adult life. Diabetologia 1998, 41:54-58.
13. Khogall S.S., Mayosi B.M., Beattle J.M., McKenna W.J., Watkins H., Poulton J. A common mitochondrial DNA variant associated with susceptibility to dilated cardiomyopathy in two different populations. Lancet 2001, 357:1265-1267.
14. Ruppert V., Nolte D., Aschenbrenner T., Pankuweit S., Funck R., Maisch B. Novel point mutations in the mitochondrial DNA detected in patients with dilated cardiomyopathy by screening the whole mitochondrial genome. Biochem Biophys Res Commun 2004, 318:535-543.
15. Weng S.W., Liou C.W., Lin T.K., Wei Y.H., Lee C.F., Eng H.L., et al. Association of mitochondrial deoxyribonucleic acid 16189 variant (T3C transition) with metabolic syndrome in Chinese adults. J Clin Endrocrinol Metabol 2005, 90:5037-5040.
16. Liou C.W., Lin T.K., Huei Weng H., Lee C.F., Chen T.L., Wei Y.H., et al. A common mitochondrial DNA variant and increased body mass index as associated factors for development of type 2 diabetes: additive effects of genetic and environmental factors. J Clin Endrocrinol Metabol 2007, 92:235-239.
17. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001, 285:2486-2497. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP).
18. Ford E.S., Giles W.H., Dietz W.H. Prevalence of the metabolic syndrome among US adults: findings from the Third National Health and Nutrition Examination Survey. JAMA 2002, 287:356-359.
19. Palmieri V.O., Grattagliano I., Portincasa P., Palasciano G. Systemic oxidative alterations are associated with visceral adiposity and liver steatosis in patients with metabolic syndrome. J Nutr 2006, 136:3022-3026.
20. Angelico F., Del Ben M., Conti R., Francioso S., Feole K., Maccioni D., et al. Non-alcoholic fatty liver syndrome: a hepatic consequence of common metabolic diseases. J Gastroenterol Hepatol 2003, 18:588-594.
21. Suzuki R., Watanabe S., Hirai Y., Akiyama K., Nishide T., Matsushima Y., et al. Abdominal wall fat index estimated by ultrasonography, for assessment of the ratio of visceral fat to subcutaneous fat in the abdomen. Am J Med 1993, 95:309-314.
22. Burke G.L., Evans G.W., Riley W.A., Sharrett A.R., Howard G., Barnes R.W., et al. Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study. Stroke 1995, 26:386-391.
23. Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging and cancer: a dawn for evolutionary medicine. Annu Rev Genet 2005, 39:359-407.
24. Maasz A., Horvatovich K., Magyari L., Talián Csaba G., Bokor S., Laczy B., et al. Search for mitochondrial DNA T4291C mutation in Hungarian patients with metabolic syndrome. Orv Hetil 2006, 147:693-696.
25. Lee H.K., Park K.S., Cho Y.M., Lee Y.Y., Pak Y.K. Mitochondria-based model for fetal origin of adult disease and insulin resistance. Ann N Y Acad Sci 2005, 1042:1-18.
26. Lin T.K., Chen S.D., Wang P.W., Wei Y.H., Lee C.F., Chen T.L., et al. Increased oxidative damage with altered antioxidative status in type 2 diabetic patients harboring the 16189 T to C variant of mitochondrial DNA. Ann N Y Acad Sci 2005, 1042:64-69.
27. Bhat A., Koul A., Sharma S., Rai E., Bukhari S.I., Dhar M.K., Bamezai R.N. The possible role of 10398A and 16189C mtDNA variants in providing susceptibility toT2DM in two North Indian populations: a replicative study. Hum Genet 2007, 120:821-826.
28. Mohlke K.L., Jackson A.U., Scott L.J., Peck E.C., HSuh Y.D., Chines P.S., et al. Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Hum Genet 2005, 118:245-254.
29. Heuten H., Goovaerts I., Ennekens G., Vrints C. Carotid artery intima-media thickness is associated with coronary artery disease. Acta Cardiol 2008, 63:309-313.
30. Morten K., Jen C., Poulton J. The 16189 variant of mtDNA in type 2 diabetes: towards a molecular mechanism [abstract]. Diabet Med 2003, 20(suppl 2):13.
31. Portincasa P., Grattagliano I., Lauterburg B.H., Palmieri V.O., Palasciano G., Stellaard F. Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis. Clin Sci 2006, 111:135-143.
32. Palasciano G., Moschetta A., Palmieri V.O., Grattagliano I., Iacobellis G., Portincasa P. Non-alcoholic fatty liver disease in the metabolic syndrome. Curr Pharm Des 2007, 13:2193-2198.
33. Kim J.H., Park K.S., Cho Y.M., Kang B.S., Kim S.K., Jeon H.J., et al. The prevalence of the mitochondrial DNA 16189 variant in non-diabetic Korean adults and its association with higher fasting glucose and body mass index. Diabet Med 2002, 19:681-684.
34. Gill-Randall R., Sherratt E.J., Thomas A.W., Gagg J.W., Lee A., Alcolado J.C. Analysis of a polycytosine tract and heteroplasmic length variation in the mitochondrial DNA Dloop of patients with diabetes, MELAS syndrome and race-matched controls. Diabet Med 2001, 18:413-416.
35. Marchington D.R., Poulton J., Sellar A., Holt I.J. Do sequence variants in the major non-coding region of the mitochondrial genome influence mitochondrial mutations associated with disease?. Hum Mol Genet 1996, 5:473-479.