Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay

Analytical Chemistry

Volumn 83, Issue 12, 2011, Pages 4996-5004

  Hemeon, Ivan ^a   Gutierrez, Jemy A ^a   Ho, Meng Chiao ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5-AZACYTIDINE; CATALYTIC DOMAINS; CHEMICAL LIBRARIES; CONTINUOUS ASSAY; DNA METHYLATION; DNA METHYLTRANSFERASES; DYNAMIC RANGE; FIREFLY LUCIFERASE; HIGH CONCENTRATION; HIGH-THROUGHPUT SCREENING; INHIBITION ACTIVITY; KINETIC PROPERTIES; LIGHT OUTPUT; METHYL GROUP; METHYLTRANSFERASES; NUCLEOSIDASE; PHOSPHORIBOSYL TRANSFERASE; PYRUVATE ORTHOPHOSPHATE DIKINASE; RAPID RESPONSE TIME; REGULATED GENES; S ADENOSYL L METHIONINES; ULTRASENSITIVE;

ALKYLATION; AMINO ACIDS; DNA; FUNCTIONAL GROUPS; GENES; LUMINESCENCE; METHYLATION; TRANSCRIPTION;

ASSAYS;

5 AZACYTOSINE; 5' METHYLTHIOADENOSINE; 5'-METHYLTHIOADENOSINE; 5-AZACYTOSINE; AZACITIDINE; CYTOSINE; DEOXYADENOSINE DERIVATIVE; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DRUG DERIVATIVE; LUCIFERASE; NUCLEOSIDE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

ARTICLE; BACTERIUM; CHEMISTRY; DNA METHYLATION; ENZYME ASSAY; ENZYMOLOGY; HUMAN; KINETICS; LIGHT; METABOLISM; METHODOLOGY;

AZACITIDINE; BACTERIA; CYTOSINE; DEOXYADENOSINES; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; ENZYME ASSAYS; HUMANS; KINETICS; LIGHT; LUCIFERASES; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; THIONUCLEOSIDES;

EID: 79959267479     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac200816m     Document Type: Article

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