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Volumn 352, Issue 1-2, 2011, Pages 125-141

The 3′-untranslated region length and AU-rich RNA location modulate RNA-protein interaction and translational control of β2- adrenergic receptor mRNA

Author keywords

2 adrenergic receptor mRNA; ARE RNA; HuR; RNA binding proteins; TIAR; Translational control

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; HUR PROTEIN; MESSENGER RNA; PROTEIN; T CELL RESTRICTED INTRACELLULAR ANTIGEN RELATED PROTEIN; UNCLASSIFIED DRUG; PRIMER DNA;

EID: 79959263596     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0747-z     Document Type: Article
Times cited : (9)

References (50)
  • 1
    • 0022485749 scopus 로고
    • Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin
    • Dixon RA, Kobilka BK, Strader DJ et al (1986) Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature 321:75-79 (Pubitemid 16080889)
    • (1986) Nature , vol.321 , Issue.6065 , pp. 75-79
    • Dixon, R.A.F.1    Kobilka, B.K.2    Strader, D.J.3
  • 2
    • 0023194433 scopus 로고
    • 2-adrenergic receptor and their putative promoter regions
    • Kobilka BK, Frielle T, Dohlman HG, Bolanowski MA, Dixon RA, Keller P, Caron MG, Lefkowitz RJ (1987) Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. J Biol Chem 262:7321-7327 (Pubitemid 17105025)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.15 , pp. 7321-7327
    • Kobilka, B.K.1    Frielle, T.2    Dohlman, H.G.3
  • 3
    • 0024040764 scopus 로고
    • Down-regulation of beta-adrenergic receptors: Agonist-induced reduction in receptor mRNA levels
    • Hadcock JR, Malbon CC (1988) Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels. Proc Natl Acad Sci USA 85:5021-5025
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5021-5025
    • Hadcock, J.R.1    Malbon, C.C.2
  • 4
    • 0030999050 scopus 로고    scopus 로고
    • 2AR- binding protein and is obligate for agonist-induced destabilization of receptor mRNA
    • DOI 10.1074/jbc.272.17.11471
    • Tholanikunnel BG, Malbon CC (1997) A 20-nucleotide (A + U)- rich element of beta2-adrenergic receptor (beta2AR) mRNA mediates binding to beta2AR-binding protein and is obligate for agonist-induced destabilization of receptor mRNA. J Biol Chem 272:11471-11478 (Pubitemid 27184156)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.17 , pp. 11471-11478
    • Tholanikunnel, B.G.1    Malbon, C.C.2
  • 6
    • 12544258221 scopus 로고    scopus 로고
    • Translational control of beta2-adrenergic receptor mRNA by T-cell-restricted intracellular antigen-related protein
    • Kandasamy K, Joseph K, Subramaniam K, Raymond JR, Tholanikunnel BG (2005) Translational control of beta2-adrenergic receptor mRNA by T-cell-restricted intracellular antigen-related protein. J Biol Chem 280:1931-1943
    • (2005) J Biol Chem , vol.280 , pp. 1931-1943
    • Kandasamy, K.1    Joseph, K.2    Subramaniam, K.3    Raymond, J.R.4    Tholanikunnel, B.G.5
  • 7
    • 0033598811 scopus 로고    scopus 로고
    • Analysis of the AU-rich elements in the 3′-untranslated region of beta2-adrenergic receptor mRNA by mutagenesis and identification of the homologous AU-rich region from different species
    • Tholanikunnel BG, Raymond JR, Malbon CC (1999) Analysis of the AU-rich elements in the 3′-untranslated region of beta 2-adrenergic receptor mRNA by mutagenesis and identification of the homologous AU-rich region from different species. Biochemistry 38:15564-15572 (Pubitemid 129503598)
    • (1999) Biochemistry , vol.38 , Issue.47 , pp. 15564-15572
    • Tholanikunnel, B.G.1    Raymond, J.R.2    Malbon, C.C.3
  • 8
    • 0037308625 scopus 로고    scopus 로고
    • Translational control by the 3′-UTR: The ends specify the means
    • DOI 10.1016/S0968-0004(03)00002-1
    • Mazumder B, Seshadri V, Fox PL (2003) Translational control by the 3′-UTR: the ends specify the means. Trends Biochem Sci 28:91-98 (Pubitemid 36165138)
    • (2003) Trends in Biochemical Sciences , vol.28 , Issue.2 , pp. 91-98
    • Mazumder, B.1    Seshadri, V.2    Fox, P.L.3
  • 9
    • 0042968976 scopus 로고    scopus 로고
    • The power of the 3′ UTR: Translational control and development
    • Kuersten S, Goodwin EB (2003) The power of the 3′ UTR: translational control and development. Nature Rev Genet 4: 626-637
    • (2003) Nature Rev Genet , vol.4 , pp. 626-637
    • Kuersten, S.1    Goodwin, E.B.2
  • 10
    • 0028788194 scopus 로고
    • AU-rich elements: Characterization and importance in mRNA degradation
    • Chen CY, Shyu AB (1995) AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem Sci 20:465-470
    • (1995) Trends Biochem Sci , vol.20 , pp. 465-470
    • Chen, C.Y.1    Shyu, A.B.2
  • 12
    • 0032526417 scopus 로고    scopus 로고
    • RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein
    • DOI 10.1093/emboj/17.12.3461
    • Peng SS, Chen CY, Xu N, Shyu AB (1998) RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein. EMBO J 17:3461-3470 (Pubitemid 28279518)
    • (1998) EMBO Journal , vol.17 , Issue.12 , pp. 3461-3470
    • Peng, S.S.-Y.1    Chen, C.-Y.A.2    Xu, N.3    Shyu, A.-B.4
  • 13
    • 0032526427 scopus 로고    scopus 로고
    • Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
    • DOI 10.1093/emboj/17.12.3448
    • Fan XC, Steitz JA (1998) Overexpression of HuR, a nuclearcytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J 17:3448-3460 (Pubitemid 28279517)
    • (1998) EMBO Journal , vol.17 , Issue.12 , pp. 3448-3460
    • Fan, X.C.1    Steitz, J.A.2
  • 14
    • 15844383918 scopus 로고    scopus 로고
    • AUF1 binding affinity to A + Urich elements correlates with rapid mRNA degradation
    • DeMaria CT, Brewer G (1996) AUF1 binding affinity to A + Urich elements correlates with rapid mRNA degradation. J Biol Chem 271:12179-12184
    • (1996) J Biol Chem , vol.271 , pp. 12179-12184
    • DeMaria, C.T.1    Brewer, G.2
  • 15
    • 13244298460 scopus 로고    scopus 로고
    • Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1
    • DOI 10.1101/gad.1282305
    • Lykke-Andersen J, Wagner E (2005) Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. Genes Dev 19:351-361 (Pubitemid 40189298)
    • (2005) Genes and Development , vol.19 , Issue.3 , pp. 351-361
    • Lykke-Andersen, J.1    Wagner, E.2
  • 16
    • 26644438803 scopus 로고    scopus 로고
    • Influence of nonameric AU-rich tristetraprolin-binding sites on mRNA deadenylation and turnover
    • DOI 10.1074/jbc.M506757200
    • Lai WS, Carrick DM, Blackshear PJ (2005) Influence of nonameric AU-rich tristetraprolin-binding Sites on mRNA deadenylation and turnover. J Biol Chem 280:34365-34377 (Pubitemid 41443163)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.40 , pp. 34365-34377
    • Lai, W.S.1    Carrick, D.M.2    Blackshear, P.J.3
  • 18
    • 0033593448 scopus 로고    scopus 로고
    • Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA
    • Gueydan C, Droogmans L, Chalon P, Huez G, Caput D, Kruys V (1999) Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA. J Biol Chem 274:2322-2326
    • (1999) J Biol Chem , vol.274 , pp. 2322-2326
    • Gueydan, C.1    Droogmans, L.2    Chalon, P.3    Huez, G.4    Caput, D.5    Kruys, V.6
  • 20
    • 0036556757 scopus 로고    scopus 로고
    • Visibly stressed: The role of eIF2, TIA-1, and stress granules in protein translation
    • Anderson P, Kedersha N (2002) Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation. Cell Stress Chaperones 7:213-221
    • (2002) Cell Stress Chaperones , vol.7 , pp. 213-221
    • Anderson, P.1    Kedersha, N.2
  • 24
    • 0030867877 scopus 로고    scopus 로고
    • Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression
    • Antic D, Keene JD (1997) Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression. Am J Hum Genet 61: 273-278 (Pubitemid 27382301)
    • (1997) American Journal of Human Genetics , vol.61 , Issue.2 , pp. 273-278
    • Antic, D.1    Keene, J.D.2
  • 25
    • 0035162672 scopus 로고    scopus 로고
    • ARED: Human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins
    • Bakheet T, Frevel M, Williams BR, Greer W, Khabar KS (2001) ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins. Nucleic Acids Res 29:246-254 (Pubitemid 32054460)
    • (2001) Nucleic Acids Research , vol.29 , Issue.1 , pp. 246-254
    • Bakheet, T.1    Frevel, M.2    Williams, B.R.G.3    Greer, W.4    Khabar, K.S.A.5
  • 27
    • 4143122397 scopus 로고    scopus 로고
    • Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
    • DOI 10.1038/sj.emboj.7600305
    • Lal A, Mazan-Mamczarz K, Kawai T, Yang X, Martindale JL, Gorospe M (2004) Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J 23: 3092-3102 (Pubitemid 39093603)
    • (2004) EMBO Journal , vol.23 , Issue.15 , pp. 3092-3102
    • Lal, A.1    Mazan-Mamczarz, K.2    Kawai, T.3    Yang, X.4    Martindale, J.L.5    Gorospe, M.6
  • 29
    • 0036351379 scopus 로고    scopus 로고
    • Ribonomics: Identifying mRNA subsets in mRNP complexes using antibodies to RNA-binding proteins and genomic arrays
    • DOI 10.1016/S1046-2023(02)00022-1, PII S1046202302000221
    • Tenenbaum SA, Lager PJ, Carson CC, Keene JD (2002) Ribonomics: identifying mRNA subsets in mRNP complexes using antibodies to RNA-binding proteins and genomic arrays. Methods 26:191-198 (Pubitemid 34969581)
    • (2002) Methods , vol.26 , Issue.2 , pp. 191-198
    • Tenenbaum, S.A.1    Lager, P.J.2    Carson, C.C.3    Keene, J.D.4
  • 30
    • 31144448042 scopus 로고    scopus 로고
    • AU-rich elements and associated factors: Are there unifying principles?
    • Barreau C, Paillard L, Osborne HB (2006) AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res 33:7138-7150
    • (2006) Nucleic Acids Res , vol.33 , pp. 7138-7150
    • Barreau, C.1    Paillard, L.2    Osborne, H.B.3
  • 32
    • 24044436193 scopus 로고    scopus 로고
    • Functionally independent AU-rich sequence motifs regulate KC (CXCL1) mRNA
    • DOI 10.1074/jbc.M502280200
    • Novotny M, Datta S, Biswas R, Hamilton T (2005) Functionally independent AU-rich sequence motifs regulate KC (CXCL1) mRNA. J Biol Chem 280:30166-30174 (Pubitemid 41216195)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.34 , pp. 30166-30174
    • Novotny, M.1    Datta, S.2    Biswas, R.3    Hamilton, T.4
  • 35
    • 20444498254 scopus 로고    scopus 로고
    • A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics
    • DOI 10.1074/jbc.M500618200
    • Fialcowitz EJ, Brewer BY, Keenan BP, Wilson GM (2005) A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics. J Biol Chem 280:22406-22417 (Pubitemid 40827896)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.23 , pp. 22406-22417
    • Fialcowitz, E.J.1    Brewer, B.Y.2    Keenan, B.P.3    Wilson, G.M.4
  • 38
    • 0034697027 scopus 로고    scopus 로고
    • Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region
    • DOI 10.1074/jbc.275.16.11750
    • Dixon DA, Kaplan CD, McIntyre TM, Zimmerman GA, Prescott SM (2000) Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3′-untranslated region. J Biol Chem 275:11750-11757 (Pubitemid 30237739)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.16 , pp. 11750-11757
    • Dixon, D.A.1    Kaplan, C.D.2    McIntyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 39
    • 0037245474 scopus 로고    scopus 로고
    • Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2
    • DOI 10.1016/S1097-2765(03)00012-1
    • Mukhopadhyay D, Houchen CW, Kennedy S, Dieckgraefe BK, Anant S (2003) Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mol Cell 11:113-126 (Pubitemid 36126595)
    • (2003) Molecular Cell , vol.11 , Issue.1 , pp. 113-126
    • Mukhopadhyay, D.1    Houchen, C.W.2    Kennedy, S.3    Dieckgraefe, B.K.4    Anant, S.5
  • 40
    • 0029126879 scopus 로고
    • MRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: Different deadenylation kinetics and uncoupling from translation
    • Chen CY, Xu N, Shyu AB (1995) mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation. Mol Cell Biol 15:5777-5788
    • (1995) Mol Cell Biol , vol.15 , pp. 5777-5788
    • Chen, C.Y.1    Xu, N.2    Shyu, A.B.3
  • 41
    • 0030027575 scopus 로고    scopus 로고
    • Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities
    • DOI 10.1074/jbc.271.5.2783
    • Dember LM, Kim ND, Liu K-Q, Anderson P (1996) Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities. J Biol Chem 271:2783-2788 (Pubitemid 26047897)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.5 , pp. 2783-2788
    • Dember, L.M.1    Kim, N.D.2    Liu, K.-Q.3    Anderson, P.4
  • 43
    • 0029655282 scopus 로고    scopus 로고
    • Translational efficiency is regulated by the length of the 3′ untranslated region
    • Tanguay RL, Gallie DR (1996) Translational efficiency is regulated by the length of the 3′ untranslated region. Mol Cell Biol 16:146-156 (Pubitemid 126506960)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.1 , pp. 146-156
    • Tanguay, R.L.1    Gallie, D.R.2
  • 44
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • DOI 10.1126/science.1155390
    • Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB (2008) Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science 320:1643-1647 (Pubitemid 351931255)
    • (2008) Science , vol.320 , Issue.5883 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 45
    • 37349050790 scopus 로고    scopus 로고
    • The role of binding site arrangement and combinatorial targeting in microRNA repression of gene expression
    • Hon LS, Zhang Z (2007) The role of binding site arrangement and combinatorial targeting in microRNA repression of gene expression. Genome Biol 8:R166, 1-18
    • (2007) Genome Biol , vol.8 , Issue.R166 , pp. 1-18
    • Hon, L.S.1    Zhang, Z.2
  • 47
    • 62649119218 scopus 로고    scopus 로고
    • Translational regulation of GluR2 in the rat hippocampus by alternative 3′ untranslated regions
    • Irier HA, Shaw R, Lau A, Feng Y, Dingledine R (2009) Translational regulation of GluR2 in the rat hippocampus by alternative 3′ untranslated regions. J Neurochem 109:584-594
    • (2009) J Neurochem , vol.109 , pp. 584-594
    • Irier, H.A.1    Shaw, R.2    Lau, A.3    Feng, Y.4    Dingledine, R.5
  • 50
    • 0036087522 scopus 로고    scopus 로고
    • UTRdb and UTRsite: Specialized databases of sequences and functional elements of 5′ and 3′ untranslated regions of eukaryotic mRNAs. Update 2002
    • Pesole G, Liuni S, Grillo G, Licciulli F, Mignone F, Gissi C, Saccone C (2002) UTRdb and UTRsite: specialized databases of sequences and functional elements of 5′ and 3′ untranslated regions of eukaryotic mRNAs. Nucleic Acids Res 30:335-340 (Pubitemid 34679578)
    • (2002) Nucleic Acids Research , vol.30 , Issue.1 , pp. 335-340
    • Pesole, G.1    Liuni, S.2    Grillo, G.3    Licciulli, F.4    Mignone, F.5    Gissi, C.6    Saccone, C.7


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