Translational regulation of GluR2 mRNAs in rat hippocampus by alternative 3′ untranslated regions

Journal of Neurochemistry

Volumn 109, Issue 2, 2009, Pages 584-594

  Irier, Hasan A ^a   Shaw, Renee ^a   Lau, Anthony ^a   Feng, Yue ^a   Dingledine, Raymond ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3 UTR; Epilepsy; GluR2; Hippocampus; Pilocarpine; Translation

Indexed keywords

GLUTAMATE RECEPTOR 2; LUCIFERASE; MESSENGER RNA; PILOCARPINE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CYTOPLASM; EPILEPTIC STATE; FIREFLY; HIPPOCAMPUS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; REGULATORY MECHANISM; RIBOSOME; TRANSLATION REGULATION; XENOPUS;

3' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; ANIMALS; FEMALE; GENE EXPRESSION REGULATION; GENES, REPORTER; HIPPOCAMPUS; MALE; PROTEIN BIOSYNTHESIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RNA, MESSENGER; XENOPUS;

MAMMALIA; RATTUS;

EID: 62649119218     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.05992.x     Document Type: Article

References (41)

1. Awobuluyi M., Lipton S. A. Sucher N. J. (2003a) Translationally distinct populations of NMDA receptor subunit NR1 mRNA in the developing rat brain. J. Neurochem. 87, 1066 1075.
2. Awobuluyi M., Vazhappilly R. Sucher N. J. (2003b) Translational activity of N-methyl-D-aspartate receptor subunit NR1 mRNA in PC12 cells. Neurosignals 12, 283 291.
3. Colbourne F., Grooms S. Y., Zukin R. S., Buchan A. M. Bennett M. V. (2003) Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia. Proc. Natl Acad. Sci. USA 100, 2906 2910.
4. Conne B., Stutz A. Vassalli J. D. (2000) The 3′ untranslated region of messenger RNA: A molecular 'hotspot' for pathology? Nat. Med. 6, 637 641.
5. Craig A. M., Blackstone C. D., Huganir R. L. Banker G. (1994) Selective clustering of glutamate and gamma-aminobutyric acid receptors opposite terminals releasing the corresponding neurotransmitters. Proc. Natl. Acad. Sci. USA 91, 12373 12377.
6. Dingledine R., Borges K., Bowie D. Traynelis S. F. (1999) The glutamate receptor ion channels. Pharmacol. Rev. 51, 7 61.
7. Ekonomou A., Smith A. L. Angelatou F. (2001) Changes in AMPA receptor binding and subunit messenger RNA expression in hippocampus and cortex in the pentylenetetrazole-induced 'kindling' model of epilepsy. Brain Res. Mol. Brain Res. 95, 27 35.
8. Feng Y., Absher D., Eberhart D. E., Brown V., Malter H. E. Warren S. T. (1997) FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association. Mol. Cell 1, 109 118.
9. Fitzgerald L. W., Ortiz J., Hamedani A. G. Nestler E. J. (1996) Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents. J. Neurosci. 16, 274 282.
10. Gorter J. A., Petrozzino J. J., Aronica E. M., Rosenbaum D. M., Opitz T., Bennett M. V., Connor J. A. Zukin R. S. (1997) Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil. J. Neurosci. 17, 6179 6188.
11. Grooms S. Y., Opitz T., Bennett M. V. Zukin R. S. (2000) Status epilepticus decreases glutamate receptor 2 mRNA and protein expression in hippocampal pyramidal cells before neuronal death. Proc. Natl Acad. Sci. USA 97, 3631 3636.
12. Grooms S. Y., Noh K. M., Regis R., Bassell G. J., Bryan M. K., Carroll R. C. Zukin R. S. (2006) Activity bidirectionally regulates AMPA receptor mRNA abundance in dendrites of hippocampal neurons. J. Neurosci. 26, 8339 8351.
13. Hershey J. W. B., Mathews M. B. Sonenberg N. (1996) Translational Control, pp. 13 15. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
14. 2+ permeability of KA-AMPA - gated glutamate receptor channels depends on subunit composition. Science 252, 851 853.
15. Huang Y., Myers S. J. Dingledine R. (1999) Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes. Nat. Neurosci. 2, 867 872.
16. Huang Y., Doherty J. J. Dingledine R. (2002) Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus. J. Neurosci. 22, 8422 8428.
17. Huang Y. S., Carson J. H., Barbarese E. Richter J. D. (2003) Facilitation of dendritic mRNA transport by CPEB. Genes Dev. 17, 638 653.
18. Huang Y. S., Kan M. C., Lin C. L. Richter J. D. (2006) CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA. EMBO J. 25, 4865 4876.
19. Ju W., Morishita W., Tsui J., Gaietta G., Deerinck T. J., Adams S. R., Garner C. C., Tsien R. Y., Ellisman M. H. Malenka R. C. (2004) Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors. Nat. Neurosci. 7, 244 253.
20. Koh D. S., Burnashev N. Jonas P. (1995) Block of native Ca(2+)-permeable AMPA receptors in rat brain by intracellular polyamines generates double rectification. J. Physiol. 486 (Pt 2 305 312.
21. Kohler M., Kornau H. C. Seeburg P. H. (1994) The organization of the gene for the functionally dominant alpha-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptor subunit GluR-B. J. Biol. Chem. 269, 17367 17370.
22. Kuersten S. Goodwin E. B. (2003) The power of the 3′ UTR: translational control and development. Nat. Rev. Genet. 4, 626 637.
23. Mameli M., Balland B., Lujan R. Luscher C. (2007) Rapid synthesis and synaptic insertion of GluR2 for mGluR-LTD in the ventral tegmental area. Science (New York) 317, 530 533.
24. Man H. Y., Lin J. W., Ju W. H., Ahmadian G., Liu L., Becker L. E., Sheng M. Wang Y. T. (2000) Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron 25, 649 662.
25. Martinez-Turrillas R., Frechilla D. Del Rio J. (2002) Chronic antidepressant treatment increases the membrane expression of AMPA receptors in rat hippocampus. Neuropharmacology 43, 1230 1237.
26. Mazumder B., Seshadri V. Fox P. L. (2003) Translational control by the 3′-UTR: the ends specify the means. Trends Biochem. Sci. 28, 91 98.
27. de Moor C. H. Richter J. D. (1999) Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA. EMBO J. 18, 2294 2303.
28. de Moor C. H., Meijer H. Lissenden S. (2005) Mechanisms of translational control by the 3′ UTR in development and differentiation. Semin. Cell Dev. Biol. 16, 49 58.
29. Myers S. J., Peters J., Huang Y., Comer M. B., Barthel F. Dingledine R. (1998) Transcriptional regulation of the GluR2 gene: neural-specific expression, multiple promoters, and regulatory elements. J. Neurosci. 18, 6723 6739.
30. Myers S. J., Huang Y., Genetta T. Dingledine R. (2004) Inhibition of glutamate receptor 2 translation by a polymorphic repeat sequence in the 5′-untranslated leaders. J. Neurosci. 24, 3489 3499.
31. Pellegrini-Giampietro D. E., Zukin R. S., Bennett M. V., Cho S. Pulsinelli W. A. (1992) Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats. Proc. Natl. Acad. Sci. USA 89, 10499 10503.
32. Pique M., Lopez J. M. Mendez R. (2006) Cytoplasmic mRNA polyadenylation and translation assays. Methods Mol. Biol. 322, 183 198.
33. Richter J. D. Sonenberg N. (2005) Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433, 477 480.
34. Song I. Huganir R. L. (2002) Regulation of AMPA receptors during synaptic plasticity. Trends Neurosci. 25, 578 588.
35. Spirin A. S. (1969) The second Sir Hans Krebs Lecture. Informosomes. Eur. J. Biochem. 10, 20 35.
36. Swanson G. T., Kamboj S. K. Cull-Candy S. G. (1997) Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition. J. Neurosci. 17, 58 69.
37. Theis M., Si K. Kandel E. R. (2003) Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus. Proc. Natl. Acad. Sci. USA 100, 9602 9607.
38. Tongiorgi E., Righi M. Cattaneo A. (1998) A non-radioactive in situ hybridization method that does not require RNAse-free conditions. J. Neurosci. Methods 85, 129 139.
39. Warner J. R., Knopf P. M. Rich A. (1963) A multiple ribosomal structure in protein synthesis. Proc. Natl. Acad. Sci. USA 49, 122 129.
40. Washburn M. S., Numberger M., Zhang S. Dingledine R. (1997) Differential dependence on GluR2 expression of three characteristic features of AMPA receptors. J. Neurosci. 17 (24 9393 9406.
41. Wells D. G., Dong X., Quinlan E. M., Huang Y. S., Bear M. F., Richter J. D. Fallon J. R. (2001) A role for the cytoplasmic polyadenylation element in NMDA receptor-regulated mRNA translation in neurons. J. Neurosci. 21, 9541 9548.