Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions

Human Immunology

Volumn 68, Issue 11, 2007, Pages 901-907

  Achyut, B R ^a   Ghoshal, Uday C ^a   Moorchung, Nikhil ^a   Mittal, Balraj ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Gastritis; Innate immunity; Polymorphism; Risk; Toll like receptor

Indexed keywords

ASPARTIC ACID; CAGA PROTEIN; GLYCINE; THREONINE; TOLL LIKE RECEPTOR 4; UREASE;

ADULT; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DNA POLYMORPHISM; DYSPEPSIA; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRITIS; GASTROINTESTINAL ENDOSCOPE; GIEMSA STAIN; HELICOBACTER PYLORI; HUMAN; INDIAN; LYMPH FOLLICLE; MAJOR CLINICAL STUDY; MALE; PRECANCER; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SCREENING;

ADULT; ALLELES; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; FEMALE; GASTRITIS; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INDIA; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PRECANCEROUS CONDITIONS; STOMACH NEOPLASMS; TOLL-LIKE RECEPTOR 4;

EID: 36849069469     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2007.10.006     Document Type: Article

References (45)

1. Blaser M.J. Helicobacter pylori and gastritis disease. Br Med J 316 (1998) 1507
2. Lee I., Lee H., Kim M., Fukumoto M., Sawada S., and Jakate S. Ethnic difference of Helicobacter pylori gastritis: Korean and Japanese gastritis is characterized by male and antrum-predominant acute foveolitis in comparison with American gastritis. World J Gastroenterol 11 (2005) 94
3. Peek Jr. R.M., Moss S.F., Tham K.T., Perez-Perez G.I., Wang S., Miller G.G., et al. Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis. J Natl Cancer Inst 89 (1997) 863
4. Xia H.H.-X., and Talley N.J. Apoptosis in gastric epithelium induced by Helicobacter pylori infection: Implications in gastric carcinogenesis. Am J Gastroenterol 96 (2001) 16
5. Kumar S., Dhar A., Srinivasan S., Jain S., Rattan A., and Sharma M.P. Antibodies to CagA protein are not predictive of serious gastroduodenal disease in Indian patients. Indian J Gastroenterol 17 (1998) 123
6. Rad R., Dossumbekova A., Neu B., Lang R., Bauer S., and Saur D. Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection. Gut 53 (2004) 1082
7. Macarthur M., Hold G.L., and El-Omar E.M. Inflammation and cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy. Am J Physiol Gastrointest Liver Physiol 286 (2004) G515
8. El-Omar E.M., Rabkin C.S., Gammon M.D., Vaughan T.L., Risch H.A., Schoenberg J.B., et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 124 (2003) 1193
9. Machado J.C., Figueiredo C., Canedo P., Pharoah P., Carvalho R., Nabais S., et al. A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology 125 (2003) 364
10. El-Omar E.M., Carrington M., Chow W.H., McColl K.E., Bream J.H., Young H.A., et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404 (2000) 398
11. Lu B., Chen M.T., Fan Y.H., Liu Y., and Meng L.N. Effects of Helicobacter pylori eradication on atrophic gastritis and intestinal metaplasia: A 3-year follow-up study. World J Gastroenterol 11 (2005) 6518
12. Zhang C., and Yamada N. Comparison of Helicobacter pylori infection and gastric mucosal histological features of gastric ulcer patients with chronic gastritis patients. World J Gastroenterol 11 (2005) 976
13. Moorchung N., Srivastava A.N., Gupta N.K., Ghoshal U.C., Achyut B.R., and Mittal B. Cytokine gene polymorphisms and the pathology of chronic gastritis. Singapore Med J 48 (2007) 447
14. Hwang I.R., Kodama T., and Kikuchi S. Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1 beta production in Helicobacter pylori infection. Gastroenterology 123 (2002) 1793
15. Hamajima N., Matsuo K., and Saito T. Interleukin 1 polymorphisms, lifestyle factors, and Helicobacter pylori infection. Jpn J Cancer Res 92 (2001) 383
16. Furuta T., El-Omar E.M., and Xiao F. Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology 123 (2002) 92
17. Kato S., Onda M., and Yamada S. Association of the IL-1 beta genetic polymorphism and gastric cancer risk in Japanese. J Gastroenterol 36 (2001) 696
18. Smith Jr. M.F., Mitchell A., Li G., Ding S., Fitzmaurice A.M., Ryan K., Crowe S., et al. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells. J Biol Chem 278 (2003) 32552
19. Mandell L., Moran A.P., Cocchiarella A., Houghton J., Taylor N., Fox J.G., et al. Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via Toll-like receptor 2 but not Toll-like receptor 4. Infect Immun 72 (2004) 6446
20. Maeda S., Akanuma M., Mitsuno Y., Hirata Y., Ogura K., Yoshida H., et al. Distinct mechanism of Helicobacter pylori-mediated NF-κB activation between gastric cancer cells and monocytic cells. J Biol Chem 276 (2001) 44856
21. Arbour N.C., Lorenz E., Schutte B.C., Zabner J., Kline J.N., Jones M., et al. TLR-4 mutations are associated with endotoxin hypo-responsiveness in humans. Nat Genet 25 (2000) 187
22. Collier-Hyams L.S., and Neish A.S. Innate immune relationship between commensal flora and the mammalian intestinal epithelium. Cell Mol Life Sci 62 (2005) 1339
23. Takeda K., and Akira S. Toll-like receptors in innate immunity. Int Immunol 17 (2005) 1
24. Rock F.L., Hardiman G., Timans J.C., Kastelein R.A., and Bazan J.F. A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci U S A 95 (1998) 588
25. Hellmig S., Fischbach W., Goebeler-Kolve M.E., Folsch U.R., Hampe J., and Schreiber S. Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma. Leuk Lymphoma 46 (2005) 869
26. Hold G.L., Rabkin C.S., Chow W.H., Smith M.G., Gammon M.D., Risch H.A., et al. A functional polymorphism of Toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology 132 (2007) 905
27. Wu M.S., Cheng T.Y., Shun C.T., Lin M.T., Chen L.C., and Lin J.T. Functional polymorphisms of CD14 and Toll-like receptor 4 in Taiwanese Chinese with Helicobacter pylori-related gastric malignancies. Hepatogastroenterology 53 (2006) 807
28. Garza Gonzalez E., Bosques-Padilla F.J., Mendoza-Ibarra S.I., Flores-Gutierrez J.P., Maldonado-Garza H.J., and Perez-Perez G.I. Assessment of the Toll-like receptor 4 Asp299gly, thr399Ile and interleukin-8 -251 polymorphisms in the risk for the development of distal gastric cancer. BMC Cancer 7 (2007) 70
29. Hofner P., Gyulai Z., Kiss Z.F., Tiszai A., Tiszlavicz L., Toth G., et al. Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes are associated with Helicobacter pylori-induced duodenal ulcer and gastritis. Helicobacter 12 (2007) 124
30. Kato I., Canzian F., Plummer M., Franceschi S., van Doorn L.J., Vivas J., et al. Polymorphisms in genes related to bacterial lipopolysaccharide/peptidoglycan signaling and gastric precancerous lesions in a population at high risk for gastric cancer. Dig Dis Sci 52 (2007) 254
31. Ghoshal U.C., Ghosh T.K., Ghoshal U., Shujaatullah F., Banerjee P.K., and Guha Mazumder D.N. In-house rapid urease test and commercial kit: Which is better?. Indian J Gastroenterol 18 (1999) 183
32. Talley N.J., Colin-Jones D., and Koch K.L. Functional dyspepsia. A classification with guidelines for diagnosis and management. Gastroenterol Int 4 (1991) 145
33. Dixon M.F., Genta R.M., and Yardley J.H. Classification and grading of gastritis. The updated Sydney system. Am J Surg Pathol 20 (1996) 1161
34. Wotherspoon A.C., Doglioni C., and Diss T.C. Regression of primary low grade gastric lymphoma of mucosal associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 342 (1993) 575
35. Filipe M.I., and Jass J.R. Intestinal Metaplasia Subtypes and Cancer Risk. In: Filipe M.I., and Jass J.R. (Eds). Gastric Carcinoma (1986), Churchill Livingstone, Edinburgh
36. Miller S., and Dykes D. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16 (1988) 1215
37. Lorenz E., Kathy L., and Frees D.A. Determination of the TLR4 genotype using allele specific PCR. Biotechniques 31 (2001) 22
38. Tseng F.C., Brown E.E., Maiese E.M., Yeager M., Welch R., Gold B.D., et al. Polymorphisms in cytokine genes and risk of Helicobacter pylori infection among Jamaican children. Helicobacter 11 (2006) 425
39. Genc M.R., Vardhana S., and Delaney M.L. Relationship between a Toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women. Eur J Obstet Gynecol Reprod Biol 116 (2004) 152
40. Correa P. Helicobacter pylori and gastric carcinogenesis. Am J Surg Pathol 19 (1995) S37
41. El-Omar E.M., Panman I.D., and Ardill J.E. Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology 109 (1995) 681
42. Lee S., Iida M., and Yao T. Risk of gastric cancer in patients with non-surgically treated peptic ulcer. Scand J Gastroenterol 25 (1990) 1223
43. Singh K., and Ghoshal U.C. Causal role of Helicobacter pylori infection in gastric cancer: An Asian enigma. World J Gastroenterol 12 (2006) 1346
44. Ghoshal UC, Tiwari S, Dhingra S, Pandey R, Ghoshal U, Tripathi S, et al. Frequency of Helicobacter pylori and CagA antibody in patients with gastric neoplasms and controls: The Indian enigma. Dig Dis Sci (in press).
45. Ghoshal U.C., Tripathi S., and Ghoshal U. The Indian enigma of frequent H. pylori Infection but infrequent gastric cancer: Is the magic key in Indian diet, host's genetic make up, or friendly bug?. Am J Gastroenterol 102 (2007) 2113