Hypermethylation of CCND2 may reflect a smoking-induced precancerous change in the lung

Journal of Oncology

Volumn , Issue , 2011, Pages

  Vesselle, Hubert ^a   Salskov, Alexander ^a   Hawes, Stephen E ^b   Stern, Joshua E ^a   Feng, Qinghua ^a   Jordan, C Diana ^a   Wiens, Linda ^a   Rasey, Janet ^a   Lu, Hiep ^a   Kiviat, Nancy B ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CYCLIN D2; RETINOIC ACID RECEPTOR BETA; SOMATOMEDIN BINDING PROTEIN 3; TRANSCRIPTION FACTOR RUNX; UVOMORULIN;

ADULT; AGED; ARTICLE; DNA METHYLATION; FEMALE; HUMAN; HUMAN TISSUE; LUNG LOBECTOMY; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRECANCER; RETROSPECTIVE STUDY; SMOKING; VODKA;

EID: 79959224147     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2011/950140     Document Type: Article

References (66)

1. Cancer Facts Figures,. American Cancer Society, Atlanta, Ga, USA, 2010
2. CDC, The 2004 United States surgeon general's report: the health consequences of smoking New South Wales Public Health Bulletin 2004 15 5-6 107
3. CDC, Annual smoking-attributable mortality, years of potential life lost, and productivity lossesUnited States, 19972001 Morbidity and Mortality Weekly Report 2005 54 25 625 628
4. Hecht S. S., Tobacco smoke carcinogens and lung cancer Journal of the National Cancer Institute 1999 91 14 1194 1210 (Pubitemid 29357186)
5. Straif K., Baan R., Grosse Y., Secretan B., El Ghissassi F., Cogliano V., Drewski D., Partanen T., Vhkangas K., Stcker I., Borlak J., Feron V. J., Marques M. M., Gustavsson P., Fletcher T., Arey J., Beland F. A., Burchiel S., Flowers L., Herbert R. A., Mukhtar H., Nesnow S., Penning T. M., Sinha R., Shimada T., Carcinogenicity of polycyclic aromatic hydrocarbons The Lancet Oncology 2005 6 12 931 932 (Pubitemid 41685225)
6. Ross J. A., Nesnow S., Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations Mutation Research 1999 424 1-2 155 166 (Pubitemid 29101616)
7. Yu D., Berlin J. A., Penning T. M., Field J., Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53 Chemical Research in Toxicology 2002 15 6 832 842 (Pubitemid 34663624)
8. Frazer-Abel A. A., Baksh S., Fosmire S. P., Willis D., Pierce A. M., Meylemans H., Linthicum D. S., Burakoff S. J., Coons T., Bellgrau D., Modiano J. F., Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells Journal of Pharmacology and Experimental Therapeutics 2004 311 2 758 769 (Pubitemid 39391565)
9. Kalra R., Singh S. P., Savage S. M., Finch G. L., Sopori M. L., Effects of cigarette smoke on immune response: chronic exposure to cigarette smoke impairs antigen-mediated signaling in T cells and depletes IP3-sensitive Ca2+ stores Journal of Pharmacology and Experimental Therapeutics 2000 293 1 166 171 (Pubitemid 30180936)
10. Moore L. E., Huang W. Y., Chung J., Hayes R. B., Epidemiologic considerations to assess altered DNA methylation from environmental exposures in cancer Annals of the New York Academy of Sciences 2003 983 181 196 (Pubitemid 36399331)
11. Lin R. K., Hsu H. S., Chang J. W., Chen C. Y., Chen J. T., Wang Y. C., Alteration of DNA methyltransferases contributes to 5′ CpG methylation and poor prognosis in lung cancer Lung Cancer 2007 55 2 205 213
12. Kwon Y. M., Park J. H., Kim H., Shim Y. M., Kim J., Han J., Park J., Kim D. H., Different susceptibility of increased DNMT1 expression by exposure to tobacco smoke according to histology in primary non-small cell lung cancer Journal of Cancer Research and Clinical Oncology 2007 133 4 219 226
13. Liu H., Zhou Y., Boggs S. E., Belinsky S. A., Liu J., Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B Oncogene 2007 26 40 5900 5910
14. Belinsky S. A., Klinge D. M., Stidley C. A., Issa J. P., Herman J. G., March T. H., Baylin S. B., Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer Cancer Research 2003 63 21 7089 7093 (Pubitemid 37413444)
15. Kim H., Young MI. K., Jin S. K., Lee H., Park J. H., Young M. S., Han J., Park J., Kim D. H., Tumor-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer Journal of Clinical Oncology 2004 22 12 2363 2370 (Pubitemid 41115393)
16. Toyooka S., Maruyama R., Toyooka K. O., McLerran D., Feng Z., Fukuyama Y., Virmani A. K., Zochbauer-Muller S., Tsukuda K., Sugio K., Shimizu N., Shimizu K., Lee H., Chen C. Y., Fong K. M., Gilcrease M., Roth J. A., Minna J. D., Gazdar A. F., Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer International Journal of Cancer 2003 103 2 153 160 (Pubitemid 35461506)
17. Toyooka S., Suzuki M., Tsuda T., Toyooka K. O., Maruyama R., Tsukuda K., Fukuyama Y., Iizasa T., Fujisawa T., Shimizu N., Minna J. D., Gazdar A. F., Dose effect of smoking on aberrant methylation in non-small cell lung cancers International Journal of Cancer 2004 110 3 462 464 (Pubitemid 38649902)
18. Hong Y. S., Roh M. S., Kim N. Y., Lee H. J., Kim H. K., Lee K. E., Kwak J. Y., Kim J. Y., Hypermethylation of p16 in Korean non-small cell lung cancer patients Journal of Korean Medical Science 2007 22 S32 S37
19. Liu Y., Lan Q., Siegfried J. M., Luketich J. D., Keohavong P., Aberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients Neoplasia 2006 8 1 46 51
20. Kondo K., Takahashi Y., Hirose Y., Nagao T., Tsuyuguchi M., Hashimoto M., Ochiai A., Monden Y., Tangoku A., The reduced expression and aberrant methylation of p16 in chromate workers with lung cancer Lung Cancer 2006 53 3 295 302 (Pubitemid 44192596)
21. Dammann R., Strunnikova M., Schagdarsurengin U., Rastetter M., Papritz M., Hattenhorst U. E., Hofmann H. S., Silber R. E., Burdach S., Hansen G., CpG island methylation and expression of tumour-associated genes in lung carcinoma European Journal of Cancer 2005 41 8 1223 1236 (Pubitemid 40725582)
22. Furonaka O., Takeshima Y., Awaya H., Ishida H., Kohno N., Inai K., Aberrant methylation of p14, p15 and p16 genes and location of the primary site in pulmonary squamous cell carcinoma Pathology International 2004 54 8 549 555 (Pubitemid 39149845)
23. Tomizawa Y., Iijima H., Nomoto T., Iwasaki Y., Otani Y., Tsuchiya S., Saito R., Dobashi K., Nakajima T., Mori M., Clinicopathological significance of aberrant methylation of RAR 2 at 3p24, RASSF1A at 3p21.3, and FHIT at 3p14.2 in patients with non-small cell lung cancer Lung Cancer 2004 46 3 305 312 (Pubitemid 39487305)
24. Suzuki M., Shigematsu H., Shames D. S., Sunaga N., Takahashi T., Shivapurkar N., Iizasa T., Minna J. D., Fujisawa T., Gazdar A. F., Methylation and gene silencing of the ras-related GTPase gene in lung and breast cancers Annals of Surgical Oncology 2007 14 4 1397 1404 (Pubitemid 46536799)
25. Kikuchi S., Yamada D., Fukami T., Maruyama T., Ito A., Asamura H., Matsuno Y., Onizuka M., Murakami Y., Hypermethylation of the TSLC1/IGSF4 promoter is associated with tobacco smoking and a poor prognosis in primary nonsmall cell lung carcinoma Cancer 2006 106 8 1751 1758
26. Divine K. K., Pulling L. C., Marron-Terada P. G., Liechty K. C., Kang T., Schwartz A. G., Bocklage T. J., Coons T. A., Gilliland F. D., Belinsky S. A., Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers International Journal of Cancer 2005 114 3 400 405 (Pubitemid 40279960)
27. Vaissire T., Hung R. J., Zaridze D., Moukeria A., Cuenin C., Fasolo V., Ferro G., Paliwal A., Hainaut P., Brennan P., Tost J., Boffetta P., Herceg Z., Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk factors Cancer Research 2009 69 1 243 252
28. Kersting M., Friedl C., Kraus A., Behn M., Pankow W., Schuermann M., Differential frequencies of p16(INK4a) promoter hypermethylation, p53 mutation, and K-ras mutation in exfoliative material mark the development of lung cancer in symptomatic chronic smokers Journal of Clinical Oncology 2000 18 18 3221 3229
29. Belinsky S. A., Nikula K. J., Palmisano W. A., Michels R., Saccomanno G., Gabrielson E., Baylin S. B., Herman J. G., Aberrant methylation of p16 is an early event in lung cancer and a potential biomarker for early diagnosis Proceedings of the National Academy of Sciences of the United States of America 1998 95 20 11891 11896
30. Kerr K. M., Galler J. S., Hagen J. A., Laird P. W., Laird-Offringa I. A., The role of DNA methylation in the development and progression of lung adenocarcinoma Disease Markers 2007 23 1-2 5 30 (Pubitemid 46333646)
31. Zchbauer-Mller S., Lam S., Toyooka S., Virmani A. K., Toyooka K. O., Seidl S., Minna J. D., Gazdar A. F., Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers International Journal of Cancer 2003 107 4 612 616 (Pubitemid 37296123)
32. Cirincione R., Lintas C., Conte D., Mariani L., Roz L., Vignola A. M., Pastorino U., Sozzi G., Methylation profile in tumor and sputum samples of lung cancer patients detected by spiral computed tomography: a nested case-control study International Journal of Cancer 2006 118 5 1248 1253 (Pubitemid 43185613)
33. Georgiou E., Valeri R., Tzimagiorgis G., Anzel J., Krikelis D., Tsilikas C., Sarikos G., Destouni C., Dimitriadou A., Kouidou S., Aberrant p16 promoter methylation among Greek lung cancer patients and smokers: correlation with smoking European Journal of Cancer Prevention 2007 16 5 396 402 (Pubitemid 47549998)
34. Belinsky S. A., Palmisano W. A., Gilliland F. D., Crooks L. A., Divine K. K., Winters S. A., Grimes M. J., Harms H. J., Tellez C. S., Smith T. M., Moots P. P., Lechner J. F., Stidley C. A., Crowell R. E., Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers Cancer Research 2002 62 8 2370 2377 (Pubitemid 34411720)
35. Feng Q., Hawes S. E., Stern J. E., Wiens L., Lu H., Zhao M. D., Jordan C. D., Kiviat N. B., Vesselle H., DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients Cancer Epidemiology Biomarkers and Prevention 2008 17 3 645 654 (Pubitemid 351469215)
36. Lee J. M., Bernstein A., p53 Mutations increase resistance to ionizing radiation Proceedings of the National Academy of Sciences of the United States of America 1993 90 12 5742 5746 (Pubitemid 23176238)
37. Byers T. E., Vena J. E., Rzepka T. F., Predilection of lung cancer for the upper lobes: an epidemiologic inquiry Journal of the National Cancer Institute 1984 72 6 1271 1275 (Pubitemid 14124251)
38. Hanson C. A., Miller J. R., Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein Gene 2005 361 1-2 1 12 (Pubitemid 41506930)
39. Sherr C. J., D-type cyclins Trends in Biochemical Sciences 1995 20 5 187 190
40. Jeanes A., Gottardi C. J., Yap A. S., Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene 2008 27 55 6920 6929
41. Alvarez S., Germain P., Alvarez R., Rodrguez-Barrios F., Gronemeyer H., de Lera A. R., Structure, function and modulation of retinoic acid receptor beta, a tumor suppressor International Journal of Biochemistry and Cell Biology 2007 39 7-8 1406 1415 (Pubitemid 47031031)
42. Weisenberger D. J., Campan M., Long T. I., Kim M., Woods C., Fiala E., Ehrlich M., Laird P. W., Analysis of repetitive element DNA methylation by MethyLight Nucleic Acids Research 2005 33 21 6823 6836 (Pubitemid 41830488)
43. Eads C. A., Lord R. V., Wickramasinghe K., Long T. I., Kurumboor S. K., Bernstein L., Peters J. H., DeMeester S. R., DeMeester T. R., Skinner K. A., Laird P. W., Epigenetic patterns in the progression of esophageal adenocarcinoma Cancer Research 2001 61 8 3410 3418 (Pubitemid 32695034)
44. Hawes S. E., Stern J. E., Feng Q., Wiens L. W., Rasey J. S., Lu H., Kiviat N. B., Vesselle H., DNA hypermethylation of tumors from non-small cell lung cancer (NSCLC) patients is associated with gender and histologic type Lung Cancer 2010 69 2 172 179
45. Virmani A., Rathi A., Heda S., Sugio K., Lewis C., Tonk V., Takahashi T., Roth J. A., Minna J. D., Euhus D. M., Gazdar A. F., Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers International Journal of Cancer 2003 107 3 341 345 (Pubitemid 37266451)
46. Kubo T., Yamamoto H., Ichimura K., Jida M., Hayashi T., Otani H., Tsukuda K., Sano Y., Kiura K., Toyooka S., DNA methylation in small lung adenocarcinoma with bronchioloalveolar carcinoma components Lung Cancer 2009 65 3 328 332
47. Castro M., Grau L., Puerta P., Gimenez L., Venditti J., Quadrelli S., Snchez-Carbayo M., Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer Journal of Translational Medicine 2010 8, article 86
48. Jeronimo C., Monteiro P., Henrique R., Dinis-Ribeiro M., Costa I., Costa V. L., Filipe L., Carvalho A. L., Hoque M. O., Pais I., Leal C., Teixeira M. R., Sidransky D., Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions Breast Cancer Research and Treatment 2008 109 1 27 34 (Pubitemid 351538751)
49. Lewis C. M., Cler L. R., Bu D. W., Zchbauer-Mller S., Milchgrub S., Naftalis E. Z., Leitch A. M., Minna J. D., Euhus D. M., Promoter hypermethylation in benign breast epithelium in relation to predicted breast cancer risk Clinical Cancer Research 2005 11 1 166 172 (Pubitemid 40081117)
50. Lee A., Kim Y., Han K., Chang S. K., Hae M. J., Sang I. S., Detection of tumor markers including carcinoembryonic antigen, APC, and cyclin D2 in fine-needle aspiration fluid of breast Archives of Pathology and Laboratory Medicine 2004 128 11 1251 1256 (Pubitemid 39441647)
51. Pu R. T., Laitala L. E., Alli P. M., Fackler M. J., Sukumar S., Clark D. P., Methylation profiling of benign and malignant breast lesions and its application to cytopathology Modern Pathology 2003 16 11 1095 1101 (Pubitemid 37414203)
52. Lehmann U., Lnger F., Feist H., Glckner S., Hasemeier B., Kreipe H., Quantitative assessment of promoter hypermethylation during breast cancer development American Journal of Pathology 2002 160 2 605 612 (Pubitemid 34160338)
53. Evron E., Umbricht C. B., Korz D., Raman V., Loeb D. M., Niranjan B., Buluwela L., Weitzman S. A., Marks J., Sukumar S., Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation Cancer Research 2001 61 6 2782 2787 (Pubitemid 32685869)
54. Evron E., Dooley W. C., Umbricht C. B., Rosenthal D., Sacchi N., Gabrielson E., Soito A. B., Hung D. T., Ljung B. M., Davidson N. E., Sukumar S., Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR The Lancet 2001 357 9265 1335 1336 (Pubitemid 32441534)
55. Sakuma M., Akahira J. I., Ito K., Niikura H., Moriya T., Okamura K., Sasano H., Yaegashi N., Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer Cancer Science 2007 98 3 380 386 (Pubitemid 46195609)
56. Tsutsui M., Iizuka N., Moribe T., Miura T., Kimura N., Tamatsukuri S., Ishitsuka H., Fujita Y., Hamamoto Y., Tsunedomi R., Iida M., Tokuhisa Y., Sakamoto K., Tamesa T., Sakaida I., Oka M., Methylated cyclin D2 gene circulating in the blood as a prognosis predictor of hepatocellular carcinoma Clinica Chimica Acta 2010 411 7-8 516 520
57. Lossos I. S., Czerwinski D. K., Alizadeh A. A., Wechser M. A., Tibshirani R., Botstein D., Levy R., Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes The New England Journal of Medicine 2004 350 18 1828 1837 (Pubitemid 38917249)
58. Waki T., Tamura G., Sato M., Motoyama T., Age-related methylation of tumor suppressor and tumor-related genes: an analysis of autopsy samples Oncogene 2003 22 26 4128 4133 (Pubitemid 36819653)
59. Euhus D. M., Bu D., Milchgrub S., Xie X. J., Bian A., Leitch A. M., Lewis C. M., DNA methylation in benign breast epithelium in relation to age and breast cancer risk Cancer Epidemiology Biomarkers and Prevention 2008 17 5 1051 1059
60. Brait M., Ford J. G., Papaiahgari S., Garza M. A., Lee J. I., Loyo M., Maldonado L., Begum S., McCaffrey L., Howerton M., Sidransky D., Emerson M. R., Ahmed S., Williams C. D., Hoque M. O., Association between lifestyle factors and CpG island methylation in a cancer-free population Cancer Epidemiology Biomarkers and Prevention 2009 18 11 2984 2991
61. Belinsky S. A., Liechty K. C., Gentry F. D., Wolf H. J., Rogers J., Vu K., Haney J., Kennedy T. C., Hirsch F. R., Miller Y., Franklin W. A., Herman J. G., Baylin S. B., Bunn P. A., Byers T., Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort Cancer Research 2006 66 6 3338 3344
62. Zchbauer-Mller S., Fong K. M., Virmani A. K., Geradts J., Gazdar A. F., Minna J. D., Aberrant promoter methylation of multiple genes in non-small cell lung cancers Cancer Research 2001 61 1 249 255 (Pubitemid 32095725)
63. Licchesi J. D. F., Westra W. H., Hooker C. M., Herman J. G., Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung Clinical Cancer Research 2008 14 9 2570 2578
64. Yue W., Dacic S., Sun Q., Landreneau R., Guo M., Zhou W., Siegfried J. M., Yu J., Zhang L., Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation Clinical Cancer Research 2007 13 15 4336 4344 (Pubitemid 47219697)
65. Esteller M., Sanchez-Cespedes M., Resell R., Sidransky D., Baylin S. B., Herman J. G., Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients Cancer Research 1999 59 1 67 70 (Pubitemid 29062958)
66. Yanagawa N., Tamura G., Oizumi H., Takahashi N., Shimazaki Y., Motoyama T., Promoter hypermethylation of tumor suppressor and tumor-related genes in non-small cell lung cancers Cancer Science 2003 94 7 589 592 (Pubitemid 36975012)