Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes

Clinical and Experimental Nephrology

Volumn 15, Issue 3, 2011, Pages 381-390

  Maeda, Shiro ^a   Koya, Daisuke ^b   Araki, Shin Ichi ^c   Babazono, Tetsuya ^d   Umezono, Tomoya ^e   Toyoda, Masao ^e   Kawai, Koichi ^f   Imanishi, Masahito ^g   Uzu, Takashi ^c   Suzuki, Daisuke ^e   Maegawa, Hiroshi ^c   Kashiwagi, Atsunori ^c   Iwamoto, Yasuhiko ^d   Nakamura, Yusuke ^h  

^a RIKEN   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^e TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f Kawai Clinic   (Japan)

^g OSAKA CITY GENERAL HOSPITAL   (Japan)

^h UNIVERSITY OF TOKYO   (Japan)

Author keywords

Association study; Diabetic nephropathy; Single nucleotide polymorphism (SNP); SIRT1

Indexed keywords

SIRTUIN; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 5; SIRTUIN 6;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HUMAN; JAPANESE; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PHENOTYPE; PROTEIN FUNCTION; PROTEINURIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; GENE FREQUENCY; HUMANS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SIRTUIN 1; SIRTUINS;

EID: 79959194484     PISSN: 13421751     EISSN: 14377799     Source Type: Journal    
DOI: 10.1007/s10157-011-0418-0     Document Type: Article

References (25)

1. U.S. Renal Data System, USRDS 2009 Annual Data Report. Atlas of chronic kidney disease and end-stage renal disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD. Accessed 21 July 2010.
2. Nakai S, Masakane I, Akiba T, Shigematsu T, Yamagata K, Watanabe Y, et al. Overview of regular dialysis treatment in Japan as of 31 December 2006. Ther Apher Dial. 2008;12:428-56.
3. Seaquist ER, Goetz FC, Rich S, Barbosa J. Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med. 1989;320:1161-5. (Pubitemid 19124296)
4. Quinn M, Angelico MC, Warram JH, Krolewski AS. Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia. 1996;39:940-5. (Pubitemid 26249113)
5. Krolewski AS, Warram JH, Rand LI, Kahn CR. Epidemiologic approach to the etiology of type 1 diabetes mellitus and its complications. N Engl J Med. 1987;317:1390-8. (Pubitemid 18052346)
6. Fava S, Azzopardi J, Hattersley AT, Watkins PJ. Increased prevalence of proteinuria in diabetic sibs of proteinuric type 2 diabetic subjects. Am J Kidney Dis. 2000;35:708-12. (Pubitemid 30185517)
7. Tanaka N, Babazono T, Saito S, Sekine A, Tsunoda T, Haneda M, et al. Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms. Diabetes. 2003;52:2848-53. (Pubitemid 37339716)
8. Shimazaki A, Kawamura Y, Kanazawa A, Sekine A, Saito S, Tsunoda T, et al. Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy. Diabetes. 2005;54:1171-8. (Pubitemid 40446333)
9. Kamiyama M, Kobayashi M, Araki S, Iida A, Tsunoda T, Kawai K, et al. Polymorphisms in the 3′ UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy. Hum Genet. 2007;122:397-407.
10. Maeda S, Kobayashi M, Araki S, Babazono T, Freedman BI, Bostrom MA, et al. A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes. PLoS Genet. 2010;6:e1000842.
11. Leak TS, Perlegas PS, Smith SG, Keene KL, Hicks PJ, Langefeld CD, et al. Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans. Ann Hum Genet. 2009;73:152-9.
12. Pezzolesi MG, Katavetin P, Kure M, Poznik GD, Skupien J, Mychaleckyj JC, et al. Confirmation of genetic associations at ELMO1 in the GoKinD collection support its role as a susceptibility gene in diabetic nephropathy. Diabetes. 2009;58:2698-702.
13. Tang SC, Leung VT, Chan LY, Wong SS, Chu DW, Leung JC, et al. The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes. Nephrol Dial Transplant. 2010;25(12):3931-4.
14. Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, et al. Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. Diabetes. 2009;58:1403-10.
15. Maeda S, Araki SI, Babazono T, Toyoda M, Umezono T, Kawai K, et al. Replication study for the association between 4 loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes. Diabetes. 2010;59(8):2075-9.
16. Imai S, Guarente L. Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases. Trends Pharmacol Sci. 2010;31:212-20.
17. Kume S, Uzu T, Kashiwagi A, Koya D. SIRT1, a calorie restriction mimetic, in a new therapeutic approach for type 2 diabetes mellitus and diabetic vascular complications. Endocr Metab Immune Disord Drug Targets. 2010;10:16-24.
18. Liang F, Kume S, Koya D. SIRT1 and insulin resistance. Nat Rev Endocrinol. 2009;5:367-73.
19. Kume S, Uzu T, Horiike K, Chin-Kanasaki M, Isshiki K, Araki S, et al. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney. J Clin Invest. 2010;120:1043-55.
20. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-5. (Pubitemid 40202029)
21. Chen D, Steele AD, Lindquist S, Guarente L. Increase in activity during calorie restriction requires Sirt1. Science. 2005;310:1641. (Pubitemid 41780779)
22. Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, et al. SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One. 2008;3:e1759.
23. Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell. 2006;127:1109-22. (Pubitemid 44894520)
24. Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 2007;450:712-6. (Pubitemid 350207685)
25. Zillikens MC, van Meurs JB, Rivadeneira F, Amin N, Hofman A, Oostra BA, et al. SIRT1 genetic variation is related to BMI and risk of obesity. Diabetes. 2009;58:2828-34.