Analysis of the effects of iron and vitamin C co-supplementation on oxidative damage, antioxidant response and inflammation in THP-1 macrophages

Clinical Biochemistry

Volumn 44, Issue 10-11, 2011, Pages 873-883

  Marcil, V ^a,b   Lavoie, J C ^a,b   Emonnot, L ^a,b   Seidman, E ^c   Levy, E ^a,b  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Antioxidant enzymes; Lipid peroxidation; NF B; PUFA; Redox status; TNF

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BUTYLCRESOL; CATALASE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRON; MALONALDEHYDE; POLYUNSATURATED FATTY ACID; SUPEROXIDE DISMUTASE; TROLOX C; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATION; LEUKEMIA CELL LINE; LIPID PEROXIDATION; MACROPHAGE; OXIDATIVE STRESS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 79958829836     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2011.04.012     Document Type: Article

References (60)

1. Thannickal V.J., Fanburg B.L. Reactive oxygen species in cell signaling. Am J Physiol Lung Cell Mol Physiol 2000, 279:L1005-L1028.
2. Alom-Ruiz S.P., Anilkumar N., Shah A.M. Reactive Oxygen Species and Endothelial Activation. Antioxid Redox Signal 2008, 10:1089-1100.
3. Griendling K.K., FitzGerald G.A. Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 2003, 108:2034-2040.
4. Sen C.K., Packer L. Antioxidant and redox regulation of gene transcription. FASEB J 1996, 10:709-720.
5. Oiknine J., Aviram M. Increased susceptibility to activation and increased uptake of low density lipoprotein by cholesterol-loaded macrophages. Arterioscler Thromb 1992, 12:745-753.
6. Forman H.J., Torres M. Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling. Am J Respir Crit Care Med 2002, 166:S4-S8.
7. Lee F.Y., Lee T.S., Pan C.C., Huang A.L., Chau L.Y. Colocalization of iron and ceroid in human atherosclerotic lesions. Atherosclerosis 1998, 138:281-288.
8. Marcil V., Delvin E., Sane A.T., Tremblay A., Levy E. Oxidative stress influences cholesterol efflux in THP-1 macrophages: role of ATP-binding cassette A1 and nuclear factors. Cardiovasc Res 2006, 72:473-482.
9. Bernotti S., Seidman E., Sinnett D., Brunet S., Dionne S., Delvin E., et al. Inflammatory reaction without endogenous antioxidant response in Caco-2 cells exposed to iron/ascorbate-mediated lipid peroxidation. Am J Physiol Gastrointest Liver Physiol 2003, 285:G898-G906.
10. Courtois F., Suc I., Garofalo C., Ledoux M., Seidman E., Levy E. Iron-ascorbate alters the efficiency of Caco-2 cells to assemble and secrete lipoproteins. Am J Physiol Gastrointest Liver Physiol 2000, 279:G12-G19.
11. Otto M., Hansen S.H., Dalgaard L., Dubois J., Badolo L. Development of an in vitro assay for the investigation of metabolism-induced drug hepatotoxicity. Cell Biol Toxicol 2008, 24:87-99.
12. Baker S.S., Baker R.D. Caco-2 cell metabolism of oxygen-derived radicals. Dig Dis Sci 1993, 38:2273-2280.
13. Yang Q., Krautmacher C., Schilling D., Pittelkow M.R., Naylor S. Simultaneous analysis of oxidized and reduced glutathione in cell extracts by capillary zone electrophoresis. Biomed Chromatogr 2002, 16:224-228.
14. Lepage G., Levy E., Ronco N., Smith L., Galeano N., Roy C.C. Direct transesterification of plasma fatty acids for the diagnosis of essential fatty acid deficiency in cystic fibrosis. J Lipid Res 1989, 30:1483-1490.
15. Pippenger C.E., Armstrong D. Regulatory antioxidant enzymes. Methods in Molecular Biology 1998, 299-313. Humana, NJ. A.D. Clifton (Ed.).
16. Babior B.M. NADPH oxidase: an update. Blood 1999, 93:1464-1476.
17. Garner B., van R.D., Dean R.T., Jessup W. Direct copper reduction by macrophages. Its role in low density lipoprotein oxidation. J Biol Chem 1997, 272:6927-6935.
18. Kunsch C., Medford R.M. Oxidative stress as a regulator of gene expression in the vasculature. Circ Res 1999, 85:753-766.
19. Welch K.D., Davis T.Z., Van Eden M.E., Aust S.D. Deleterious iron-mediated oxidation of biomolecules. Free Radic Biol Med 2002, 32:577-583.
20. Aust S.D., Svingen B.A. The role of iron in enzymatic lipid peroxidation. Free Radicals in Biology 1982, 1-28. Academic Press, New York. W.A. Pryor (Ed.).
21. Brunet S., Thibault L., Lepage G., Seidman E.G., Dube N., Levy E. Modulation of endoplasmic reticulum-bound cholesterol regulatory enzymes by iron/ascorbate-mediated lipid peroxidation. Free Radic Biol Med 2000, 28:46-54.
22. Brasitus T.A., Davidson N.O., Schachter D. Variations in dietary triacylglycerol saturation alter the lipid composition and fluidity of rat intestinal plasma membranes. Biochim Biophys Acta 1985, 812:460-472.
23. Bachowski G.J., Thomas J.P., Girotti A.W. Ascorbate-enhanced lipid peroxidation in photooxidized cell membranes: cholesterol product analysis as a probe of reaction mechanism. Lipids 1988, 23:580-586.
24. Jourd'Heuil D., Vaananen P., Meddings J.B. Lipid peroxidation of the brush-border membrane: membrane physical properties and glucose transport. Am J Physiol 1993, 264:G1009-G1015.
25. Siener R., Alteheld B., Terjung B., Junghans B., Bitterlich N., Stehle P., et al. Change in the fatty acid pattern of erythrocyte membrane phospholipids after oral supplementation of specific fatty acids in patients with gastrointestinal diseases. Eur J Clin Nutr 2010, 64:410-418.
26. Cotogni P., Muzio G., Trombetta A., Ranieri V.M., Canuto R.A. Impact of the omega-3 to omega-6 polyunsaturated fatty acid ratio on cytokine release in human alveolar cells. JPEN J Parenter Enteral Nutr 2011, 35:114-121.
27. Dupertuis Y.M., Meguid M.M., Pichard C. Colon cancer therapy: new perspectives of nutritional manipulations using polyunsaturated fatty acids. Curr Opin Clin Nutr Metab Care 2007, 10:427-432.
28. Darmaun D., Smith S.D., Sweeten S., Hartman B.K., Welch S., Mauras N. Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: apparent resistance to N-acetylcysteine supplementation. Pediatr Diabetes 2008, 9:577-582.
29. Kataja-Tuomola M.K., Kontto J.P., Mannisto S., Albanes D., Virtamo J.R. Effect of alpha-tocopherol and beta-carotene supplementation on macrovascular complications and total mortality from diabetes: results of the ATBC Study. Ann Med 2010, 42:178-186.
30. Kosower N.S., Kosower E.M. The glutathione status of cells. Int Rev Cytol 1978, 54:109-160.
31. Meister A., Anderson M.E. Glutathione. Annu Rev Biochem 1983, 52:711-760.
32. Meister A. Glutathione metabolism and its selective modification. J Biol Chem 1988, 263:17205-17208.
33. Jones D.P. Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol 2002, 348:93-112.
34. Schafer F.Q., Buettner G.R. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med 2001, 30:1191-1212.
35. Carroll M.C., Outten C.E., Proescher J.B., Rosenfeld L., Watson W.H., Whitson L.J., et al. The effects of glutaredoxin and copper activation pathways on the disulfide and stability of Cu, Zn superoxide dismutase. J Biol Chem 2006, 281:28648-28656.
36. Banci L., Bertini I., Cantini F., D'Amelio N., Gaggelli E. Human SOD1 before harboring the catalytic metal: solution structure of copper-depleted, disulfide-reduced form. J Biol Chem 2006, 281:2333-2337.
37. Caruano-Yzermans A.L., Bartnikas T.B., Gitlin J.D. Mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase. J Biol Chem 2006, 281:13581-13587.
38. Brown N.M., Torres A.S., Doan P.E., O'Halloran T.V. Oxygen and the copper chaperone CCS regulate posttranslational activation of Cu, Zn superoxide dismutase. Proc Nat Acad Sci U S A 2004, 101:5518-5523.
39. Arnesano F., Banci L., Bertini I., Martinelli M., Furukawa Y., O'Halloran TV. The unusually stable quaternary structure of human Cu, Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status. J Biol Chem 2004, 279:47998-48003.
40. Holvoet P., Davey P.C., De K.D., Doukoure M., Deridder E., Bochaton-Piallat M.L., et al. Oxidized low-density lipoprotein correlates positively with toll-like receptor 2 and interferon regulatory factor-1 and inversely with superoxide dismutase-1 expression: studies in hypercholesterolemic swine and THP-1 cells. Arterioscler Thromb Vasc Biol 2006, 26:1558-1565.
41. Didion S.P., Ryan M.J., Didion L.A., Fegan P.E., Sigmund C.D., Faraci F.M. Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. Circ Res 2002, 91:938-944.
42. Veerareddy S., Cooke C.L., Baker P.N., Davidge S.T. Gender differences in myogenic tone in superoxide dismutase knockout mouse: animal model of oxidative stress. Am J Physiol Heart Circ Physiol 2004, 287:H40-H45.
43. Baumbach G.L., Sigmund C.D., Faraci F.M. Structure of cerebral arterioles in mice deficient in expression of the gene for endothelial nitric oxide synthase. Circ Res 2004, 95:822-829.
44. Faraci F.M., Didion S.P. Vascular protection: superoxide dismutase isoforms in the vessel wall. Arterioscler Thromb Vasc Biol 2004, 24:1367-1373.
45. Mamo L.B., Suliman H.B., Giles B.L., Auten R.L., Piantadosi C.A., Nozik-Grayck E. Discordant extracellular superoxide dismutase expression and activity in neonatal hyperoxic lung. Am J Respir Crit Care Med 2004, 170:313-318.
46. Jeney V., Itoh S., Wendt M., Gradek Q., Ushio-Fukai M., Harrison D.G., et al. Role of antioxidant-1 in extracellular superoxide dismutase function and expression. Circ Res 2005, 96:723-729.
47. Marklund S.L. Properties of extracellular superoxide dismutase from human lung. Biochem J 1984, 220:269-272.
48. Hink H.U., Santanam N., Dikalov S., McCann L., Nguyen A.D., Parthasarathy S., et al. Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity. Arterioscler Thromb Vasc Biol 2002, 22:1402-1408.
49. Liou H.C., Baltimore D. Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system. Curr Opin Cell Biol 1993, 5:477-487.
50. Baeuerle P.A., Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 1994, 12:141-179.
51. Hulten L.M., Lindmark H., Schersten H., Wiklund O., Nilsson FN, Riise G.C. Butylated hydroxytoluene and N-acetylcysteine attenuates tumor necrosis factor-alpha (TNF-alpha) secretion and TNF-alpha mRNA expression in alveolar macrophages from human lung transplant recipients in vitro. Transplantation 1998, 66:364-369.
52. Gao L., Mann G.E. Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling. Cardiovasc Res 2009, 82:9-20.
53. Huang X., Sun M., Li D., Liu J., Guo H., Dong Y., et al. Augmented NADPH oxidase activity and p22phox expression in monocytes underlie oxidative stress of patients with type 2 diabetes mellitus. Diabetes Res Clin Pract 2011.
54. Vincent A.M., Kato K., McLean L.L., Soules M.E., Feldman E.L. Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanisms. Antioxid Redox Signal 2009, 11:425-438.
55. Howard B.V., Best L.G., Galloway J.M., Howard W.J., Jones K., Lee E.T., et al. Coronary heart disease risk equivalence in diabetes depends on concomitant risk factors. Diabetes Care 2006, 29:391-397.
56. Juutilainen A., Lehto S., Ronnemaa T., Pyorala K., Laakso M. Type 2 diabetes as a "coronary heart disease equivalent": an 18-year prospective population-based study in Finnish subjects. Diabetes Care 2005, 28:2901-2907.
57. Balkwill F., Charles K.A., Mantovani A. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 2005, 7:211-217.
58. Reuter S., Gupta S.C., Chaturvedi M.M., Aggarwal B.B. Oxidative stress, inflammation, and cancer: how are they linked?. Free Radic Biol Med 2010, 49:1603-1616.
59. Samet J.M., Avila-Tang E., Boffetta P., Hannan L.M., Olivo-Marston S., Thun M.J., et al. Lung cancer in never smokers: clinical epidemiology and environmental risk factors. Clin Cancer Res 2009, 15:5626-5645.
60. Key T.J. Fruit and vegetables and cancer risk. Br J Cancer 2011, 104:6-11.