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Volumn 236, Issue 4, 2011, Pages 375-389

Current status of experimental therapeutics for head and neck cancer

Author keywords

Gene therapy; Head and neck cancer; Molecular inhibitors; Monoclonal antibodies; Photodynamic therapy

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CETUXIMAB; CISPLATIN; CONTUSUGENE LADENOVEC; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FLUOROURACIL; GEFITINIB; GENDICINE; GENE THERAPY AGENT; HEMATOPORPHYRIN DERIVATIVE; INTERLEUKIN 2; IRINOTECAN; MATUZUMAB; METHOTREXATE; NIMOTUZUMAB; ONYX 015; PANITUMUMAB; PEMETREXED; PHOTOFRIN; PLACEBO; PLATINUM DERIVATIVE; PROTEIN P53; RADP53; SUNITINIB; TEMOPORFIN; TRANSFORMING GROWTH FACTOR ALPHA; TRASTUZUMAB; UNCLASSIFIED DRUG; MONOCLONAL ANTIBODY;

EID: 79958803599     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2010.010354     Document Type: Review
Times cited : (33)

References (84)
  • 2
    • 34548428839 scopus 로고    scopus 로고
    • Meta-analyses of chemotherapy in head and neck cancer (MACH-NC): An update
    • Pignon JP, le Maitre A, Bourhis J. Meta-analyses of chemotherapy in head and neck cancer (MACH-NC): an update. Int J Radiat Oncol Biol Phys 2007;69:S112-S114
    • (2007) Int J Radiat Oncol Biol Phys , vol.69
    • Pignon, J.P.1    le Maitre, A.2    Bourhis, J.3
  • 3
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000;103:211-225
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 4
    • 0242298117 scopus 로고    scopus 로고
    • Molecular pathogenesis of head and neck squamous cell carcinoma
    • Hardisson D. Molecular pathogenesis of head and neck squamous cell carcinoma. Eur Arch Otorhinolaryngol 2003;260:502-508
    • (2003) Eur Arch Otorhinolaryngol , vol.260 , pp. 502-508
    • Hardisson, D.1
  • 5
    • 0037115674 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
    • Ang KK, Berkey BA, Tu X, Zhang HZ, Katz R, Hammond EH, Fu KK, Milas L. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 2002;62:7350-7356
    • (2002) Cancer Res , vol.62 , pp. 7350-7356
    • Ang, K.K.1    Berkey, B.A.2    Tu, X.3    Zhang, H.Z.4    Katz, R.5    Hammond, E.H.6    Fu, K.K.7    Milas, L.8
  • 6
    • 33645048171 scopus 로고    scopus 로고
    • Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer
    • Kong A, Leboucher P, Leek R, Calleja V, Winter S, Harris A, Parker PJ, Larijani B. Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer. Cancer Res 2006;66:2834-2843
    • (2006) Cancer Res , vol.66 , pp. 2834-2843
    • Kong, A.1    Leboucher, P.2    Leek, R.3    Calleja, V.4    Winter, S.5    Harris, A.6    Parker, P.J.7    Larijani, B.8
  • 7
    • 0028155340 scopus 로고
    • An allelotype of squamous carcinoma of the head and neck using microsatellite markers
    • Ah-See KW, Cooke TG, Pickford IR, Soutar D, Balmain A. An allelotype of squamous carcinoma of the head and neck using microsatellite markers. Cancer Res 1994;54:1617-1621
    • (1994) Cancer Res , vol.54 , pp. 1617-1621
    • Ah-See, K.W.1    Cooke, T.G.2    Pickford, I.R.3    Soutar, D.4    Balmain, A.5
  • 8
    • 0026768143 scopus 로고
    • Overexpression of p53 in head and neck cancer
    • Watling DL, Gown AM, Coltrera MD. Overexpression of p53 in head and neck cancer. Head Neck 1992;14:437-444
    • (1992) Head Neck , vol.14 , pp. 437-444
    • Watling, D.L.1    Gown, A.M.2    Coltrera, M.D.3
  • 10
    • 0032473823 scopus 로고    scopus 로고
    • TP53 DNA contact mutations are selectively associated with allelic loss and have a strong clinical impact in head and neck cancer
    • Erber R, Conradt C, Homann N, Enders C, Finckh M, Dietz A, Weidauer H, Bosch FX. TP53 DNA contact mutations are selectively associated with allelic loss and have a strong clinical impact in head and neck cancer. Oncogene 1998;16:1671-1679
    • (1998) Oncogene , vol.16 , pp. 1671-1679
    • Erber, R.1    Conradt, C.2    Homann, N.3    Enders, C.4    Finckh, M.5    Dietz, A.6    Weidauer, H.7    Bosch, F.X.8
  • 12
    • 0028978183 scopus 로고
    • Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • Deng C, Zhang P, Harper JW, Elledge SJ, Leder P. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995;82:675-684
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 13
    • 0027818396 scopus 로고
    • A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis
    • Fujiwara T, Grimm EA, Mukhopadhyay T, Cai DW, Owen-Schaub LB, Roth JA. A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis. Cancer Res 1993;53:4129-4133
    • (1993) Cancer Res , vol.53 , pp. 4129-4133
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Cai, D.W.4    Owen-Schaub, L.B.5    Roth, J.A.6
  • 17
    • 77955693980 scopus 로고    scopus 로고
    • Targeting epidermal growth factor receptor in head and neck cancer: Lessons learned from cetuximab
    • Moon CS, Chae YK, Lee J. Targeting epidermal growth factor receptor in head and neck cancer: lessons learned from cetuximab. Exp Biol Med 2010;235:907-920
    • (2010) Exp Biol Med , vol.235 , pp. 907-920
    • Moon, C.S.1    Chae, Y.K.2    Lee, J.3
  • 18
    • 0037010086 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer
    • Herbst RS, Hong WK. IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer. Semin Oncol 2002;29:18-30
    • (2002) Semin Oncol , vol.29 , pp. 18-30
    • Herbst, R.S.1    Hong, W.K.2
  • 19
    • 0037010077 scopus 로고    scopus 로고
    • Safety experience with IMC-C225, an anti-epidermal growth factor receptor antibody
    • Needle MN. Safety experience with IMC-C225, an anti-epidermal growth factor receptor antibody. Semin Oncol 2002;29:55-60
    • (2002) Semin Oncol , vol.29 , pp. 55-60
    • Needle, M.N.1
  • 22
    • 24944490558 scopus 로고    scopus 로고
    • Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck
    • Herbst RS, Arquette M, Shin DM, Dicke K, Vokes EE, Azarnia N, Hong WK, Kies MS. Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck. J Clin Oncol 2005;23:5578-5587
    • (2005) J Clin Oncol , vol.23 , pp. 5578-5587
    • Herbst, R.S.1    Arquette, M.2    Shin, D.M.3    Dicke, K.4    Vokes, E.E.5    Azarnia, N.6    Hong, W.K.7    Kies, M.S.8
  • 23
    • 23844523253 scopus 로고    scopus 로고
    • Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck
    • Baselga J, Trigo JM, Bourhis J, Tortochaux J, Cortes-Funes H, Hitt R, Gascon P, Amellal N, Harstrick A, Eckardt A. Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 2005;23:5568-5577
    • (2005) J Clin Oncol , vol.23 , pp. 5568-5577
    • Baselga, J.1    Trigo, J.M.2    Bourhis, J.3    Tortochaux, J.4    Cortes-Funes, H.5    Hitt, R.6    Gascon, P.7    Amellal, N.8    Harstrick, A.9    Eckardt, A.10
  • 25
    • 33144461661 scopus 로고    scopus 로고
    • Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: An Eastern Cooperative Oncology Group study
    • Burtness B, Goldwasser MA, Flood W, Mattar B, Forastiere AA. Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study. J Clin Oncol 2005;23:8646-8654
    • (2005) J Clin Oncol , vol.23 , pp. 8646-8654
    • Burtness, B.1    Goldwasser, M.A.2    Flood, W.3    Mattar, B.4    Forastiere, A.A.5
  • 27
    • 33644971314 scopus 로고    scopus 로고
    • Concurrent cetuximab, cisplatin, and concomitant boost radiotherapy for loco regionally advanced, squamous cell head and neck cancer: A pilot phase II study of a new combined-modality paradigm
    • Pfister DG, Su YB, Kraus DH, Wolden SL, Lis E, Aliff TB, Zahalsky AJ, Lake S, Needle MN, Shaha AR, Shah JP, Zelefsky MJ. Concurrent cetuximab, cisplatin, and concomitant boost radiotherapy for loco regionally advanced, squamous cell head and neck cancer: a pilot phase II study of a new combined-modality paradigm. J Clin Oncol 2006;24:1072-1078
    • (2006) J Clin Oncol , vol.24 , pp. 1072-1078
    • Pfister, D.G.1    Su, Y.B.2    Kraus, D.H.3    Wolden, S.L.4    Lis, E.5    Aliff, T.B.6    Zahalsky, A.J.7    Lake, S.8    Needle, M.N.9    Shaha, A.R.10    Shah, J.P.11    Zelefsky, M.J.12
  • 28
    • 34250180582 scopus 로고    scopus 로고
    • Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
    • Vermorken JB, Trigo J, Hitt R, Koralewski P, Diaz-Rubio E, Rolland F, Knecht R, Amellal N, Schueler M, Baselga J. Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol 2007;25:2171-2177
    • (2007) J Clin Oncol , vol.25 , pp. 2171-2177
    • Vermorken, J.B.1    Trigo, J.2    Hitt, R.3    Koralewski, P.4    Diaz-Rubio, E.5    Rolland, F.6    Knecht, R.7    Amellal, N.8    Schueler, M.9    Baselga, J.10
  • 29
    • 0035874898 scopus 로고    scopus 로고
    • Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2
    • Cuello M, Ettenberg SA, Clark AS, Keane MM, Posner RH, Nau MM, Dennis PA, Lipkowitz S. Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2. Cancer Res 2001;61:4892-4900
    • (2001) Cancer Res , vol.61 , pp. 4892-4900
    • Cuello, M.1    Ettenberg, S.A.2    Clark, A.S.3    Keane, M.M.4    Posner, R.H.5    Nau, M.M.6    Dennis, P.A.7    Lipkowitz, S.8
  • 30
    • 0037089544 scopus 로고    scopus 로고
    • Antihuman epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab enhances cytolytic activity of class I-restricted HER2-specific T lymphocytes against HER2-overexpressing tumor cells
    • zum Buschenfelde CM, Hermann C, Schmidt B, Peschel C, Bernhard H. Antihuman epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab enhances cytolytic activity of class I-restricted HER2-specific T lymphocytes against HER2-overexpressing tumor cells. Cancer Res 2002;62:2244-2247
    • (2002) Cancer Res , vol.62 , pp. 2244-2247
    • Zum, B.C.M.1    Hermann, C.2    Schmidt, B.3    Peschel, C.4    Bernhard, H.5
  • 33
    • 0037674062 scopus 로고    scopus 로고
    • Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
    • Cohen EE, Rosen F, Stadler WM, Recant W, Stenson K, Huo D, Vokes EE. Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2003;21:1980-1987
    • (2003) J Clin Oncol , vol.21 , pp. 1980-1987
    • Cohen, E.E.1    Rosen, F.2    Stadler, W.M.3    Recant, W.4    Stenson, K.5    Huo, D.6    Vokes, E.E.7
  • 36
    • 1842772526 scopus 로고    scopus 로고
    • Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
    • Soulieres D, Senzer NN, Vokes EE, Hidalgo M, Agarwala SS, Siu LL. Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck. J Clin Oncol 2004;22:77-85
    • (2004) J Clin Oncol , vol.22 , pp. 77-85
    • Soulieres, D.1    Senzer, N.N.2    Vokes, E.E.3    Hidalgo, M.4    Agarwala, S.S.5    Siu, L.L.6
  • 40
    • 0029060026 scopus 로고
    • Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck
    • Kiaris H, Spandidos DA, Jones AS, Vaughan ED, Field JK. Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck. Br J Cancer 1995;72:123-128
    • (1995) Br J Cancer , vol.72 , pp. 123-128
    • Kiaris, H.1    Spandidos, D.A.2    Jones, A.S.3    Vaughan, E.D.4    Field, J.K.5
  • 41
    • 33646504884 scopus 로고    scopus 로고
    • Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancer
    • Graeven U, Kremer B, Sudhoff T, Killing B, Rojo F, Weber D, Tillner J, Unal C, Schmiegel W. Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancer. Br J Cancer 2006;94:1293-1299
    • (2006) Br J Cancer , vol.94 , pp. 1293-1299
    • Graeven, U.1    Kremer, B.2    Sudhoff, T.3    Killing, B.4    Rojo, F.5    Weber, D.6    Tillner, J.7    Unal, C.8    Schmiegel, W.9
  • 42
    • 33646870539 scopus 로고    scopus 로고
    • A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC)
    • Kollmannsberger C, Schittenhelm M, Honecker F, Tillner J, Weber D, Oechsle K, Kanz L, Bokemeyer C. A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC). Ann Oncol 2006;17:1007-1013
    • (2006) Ann Oncol , vol.17 , pp. 1007-1013
    • Kollmannsberger, C.1    Schittenhelm, M.2    Honecker, F.3    Tillner, J.4    Weber, D.5    Oechsle, K.6    Kanz, L.7    Bokemeyer, C.8
  • 45
    • 34250208469 scopus 로고    scopus 로고
    • Phase I/II trial of erlotinib and cisplatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: A Princess Margaret Hospital phase II consortium and National Cancer Institute of Canada Clinical Trials Group Study
    • Siu LL, Soulieres D, Chen EX, Pond GR, Chin SF, Francis P, Harvey L, Klein M, Zhang W, Dancey J, Eisenhauer EA, Winquist E. Phase I/II trial of erlotinib and cisplatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: a Princess Margaret Hospital phase II consortium and National Cancer Institute of Canada Clinical Trials Group Study. J Clin Oncol 2007;25:2178-2183
    • (2007) J Clin Oncol , vol.25 , pp. 2178-2183
    • Siu, L.L.1    Soulieres, D.2    Chen, E.X.3    Pond, G.R.4    Chin, S.F.5    Francis, P.6    Harvey, L.7    Klein, M.8    Zhang, W.9    Dancey, J.10    Eisenhauer, E.A.11    Winquist, E.12
  • 46
    • 63149136088 scopus 로고    scopus 로고
    • Cetuximab (C) and bevacizumab (B) in patients with recurrent or metastatic head and neck squamous cell carcinoma (SCCHN): An interim analysis
    • Kies MS, Gibson MK, Kim SW, Savvides G, Bumenschein R, Worden F, Chen H, Grandis J, Argiris AE. Cetuximab (C) and bevacizumab (B) in patients with recurrent or metastatic head and neck squamous cell carcinoma (SCCHN): an interim analysis. J Clin Oncol 2008;26:abstr. 6072
    • (2008) J Clin Oncol , vol.26 , pp. 6072
    • Kies, M.S.1    Gibson, M.K.2    Kim, S.W.3    Savvides, G.4    Bumenschein, R.5    Worden, F.6    Chen, H.7    Grandis, J.8    Argiris, A.E.9
  • 47
    • 68049109938 scopus 로고    scopus 로고
    • Pemetrexed (P) and bevacizumab (B) in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC): Updated results of a phase II trial
    • Feinstein TM, Raez LE, Rajasenan KK. Pemetrexed (P) and bevacizumab (B) in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC): updated results of a phase II trial. J Clin Oncol 2008;26:6069
    • (2008) J Clin Oncol , vol.26 , pp. 6069
    • Feinstein, T.M.1    Raez, L.E.2    Rajasenan, K.K.3
  • 50
    • 0242694530 scopus 로고    scopus 로고
    • Current status of gene therapy for lung cancer and head and neck cancer
    • Moon C, Oh Y, Roth JA. Current status of gene therapy for lung cancer and head and neck cancer. Clin Cancer Res 2003;9:5055-5067
    • (2003) Clin Cancer Res , vol.9 , pp. 5055-5067
    • Moon, C.1    Oh, Y.2    Roth, J.A.3
  • 52
    • 0028069906 scopus 로고
    • Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus
    • Liu TJ, Zhang WW, Taylor DL, Roth JA, Goepfert H, Clayman GL. Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus. Cancer Res 1994;54:3662-3667
    • (1994) Cancer Res , vol.54 , pp. 3662-3667
    • Liu, T.J.1    Zhang, W.W.2    Taylor, D.L.3    Roth, J.A.4    Goepfert, H.5    Clayman, G.L.6
  • 58
    • 0033693231 scopus 로고    scopus 로고
    • Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
    • Nemunaitis J, Ganly I, Khuri F, Arseneau J, Kuhn J, McCarty T, Landers S, Maples P, Romel L, Randlev B, Reid T, Kaye S, Kirn D. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res 2000;60:6359-6366
    • (2000) Cancer Res , vol.60 , pp. 6359-6366
    • Nemunaitis, J.1    Ganly, I.2    Khuri, F.3    Arseneau, J.4    Kuhn, J.5    McCarty, T.6    Landers, S.7    Maples, P.8    Romel, L.9    Randlev, B.10    Reid, T.11    Kaye, S.12    Kirn, D.13
  • 61
    • 0033022039 scopus 로고    scopus 로고
    • P53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication
    • Harada JN, Berk AJ. p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication. J Virol 1999;73:5333-5344
    • (1999) J Virol , vol.73 , pp. 5333-5344
    • Harada, J.N.1    Berk, A.J.2
  • 62
    • 0034133571 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous stem cell rescue in the outpatient setting
    • Dix SP, Geller RB. High-dose chemotherapy with autologous stem cell rescue in the outpatient setting. Oncology (Williston Park) 2000;14:171-185
    • (2000) Oncology (Williston Park) , vol.14 , pp. 171-185
    • Dix, S.P.1    Geller, R.B.2
  • 64
    • 0030917202 scopus 로고    scopus 로고
    • ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
    • Heise C, Sampson-Johannes A, Williams A, McCormick F, Von Hoff DD, Kirn DH. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat Med 1997;3:639-645
    • (1997) Nat Med , vol.3 , pp. 639-645
    • Heise, C.1    Sampson-Johannes, A.2    Williams, A.3    McCormick, F.4    von Hoff, D.D.5    Kirn, D.H.6
  • 65
    • 0034489718 scopus 로고    scopus 로고
    • Efficacy with a replication-selective adenovirus plus cisplatin-based chemotherapy: Dependence on sequencing but not p53 functional status or route of administration
    • Heise C, Lemmon M, Kirn D. Efficacy with a replication-selective adenovirus plus cisplatin-based chemotherapy: dependence on sequencing but not p53 functional status or route of administration. Clin Cancer Res 2000;6:4908-4914
    • (2000) Clin Cancer Res , vol.6 , pp. 4908-4914
    • Heise, C.1    Lemmon, M.2    Kirn, D.3
  • 68
    • 24944454988 scopus 로고    scopus 로고
    • Current status of gendicine in China: Recombinant human Ad-p53 agent for treatment of cancers
    • Peng Z. Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers. Hum Gene Ther 2005;16:1016-1027
    • (2005) Hum Gene Ther , vol.16 , pp. 1016-1027
    • Peng, Z.1
  • 70
    • 77956397887 scopus 로고    scopus 로고
    • Photodynamic therapy of head and neck cancers
    • Biel MA. Photodynamic therapy of head and neck cancers. Methods Mol Biol 2010;635:281-293
    • (2010) Methods Mol Biol , vol.635 , pp. 281-293
    • Biel, M.A.1
  • 71
    • 77951452631 scopus 로고    scopus 로고
    • Recent advances in surgery for head and neck cancer
    • de Bree R, Leemans CR. Recent advances in surgery for head and neck cancer. Curr Opin Oncol 2010;22:186-193
    • (2010) Curr Opin Oncol , vol.22 , pp. 186-193
    • de Bree, R.1    Leemans, C.R.2
  • 73
    • 70350567170 scopus 로고    scopus 로고
    • Photodynamic therapy with metatetrahydroxyphenylchlorin (Foscan) in the management of squamous cell carcinoma of the head and neck: Experience with 35 patients
    • Lorenz KJ, Maier H. Photodynamic therapy with metatetrahydroxyphenylchlorin (Foscan) in the management of squamous cell carcinoma of the head and neck: experience with 35 patients. Eur Arch Otorhinolaryngol 2009;266:1937-1944
    • (2009) Eur Arch Otorhinolaryngol , vol.266 , pp. 1937-1944
    • Lorenz, K.J.1    Maier, H.2
  • 74
    • 1442300736 scopus 로고    scopus 로고
    • MTHPC-mediated photodynamic therapy in patients with advanced, incurable head and neck cancer: A multicenter study of 128 patients
    • D'Cruz AK, Robinson MH, Biel MA. mTHPC-mediated photodynamic therapy in patients with advanced, incurable head and neck cancer: a multicenter study of 128 patients. Head Neck 2004;26:232-240
    • (2004) Head Neck , vol.26 , pp. 232-240
    • D'cruz, A.K.1    Robinson, M.H.2    Biel, M.A.3
  • 76
    • 77952300116 scopus 로고    scopus 로고
    • Photodynamic therapy in the therapy for recurrent/persistent nasopharyngeal cancer
    • Wildman MA, Nyst HJ, Karakullukcu B, Tan BI. Photodynamic therapy in the therapy for recurrent/persistent nasopharyngeal cancer. Head Neck Oncolo 2009;1:40-45
    • (2009) Head Neck Oncolo , vol.1 , pp. 40-45
    • Wildman, M.A.1    Nyst, H.J.2    Karakullukcu, B.3    Tan, B.I.4
  • 79
    • 77957161787 scopus 로고    scopus 로고
    • Head and neck cancer-Part 1: Epidemiology, presentation, and prevention
    • Mehanna H, Paleri V, West CM, Nutting C. Head and neck cancer-Part 1: Epidemiology, presentation, and prevention. BMJ 2010;341:c4684
    • (2010) BMJ , vol.341
    • Mehanna, H.1    Paleri, V.2    West, C.M.3    Nutting, C.4
  • 81
    • 40049089468 scopus 로고    scopus 로고
    • Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway
    • Sos ML, Zander T, Thomas RK, Staratschek-Jox A, Claasen J, Wolf J. Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway. J Thorac Oncol 2008;3:170-173
    • (2008) J Thorac Oncol , vol.3 , pp. 170-173
    • Sos, M.L.1    Zander, T.2    Thomas, R.K.3    Staratschek-Jox, A.4    Claasen, J.5    Wolf, J.6
  • 82
    • 4444324184 scopus 로고    scopus 로고
    • Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck
    • Chen Z, Zhang X, Li M, Wang Z, Wieand HS, Grandis JR, Shin DM. Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck. Clin Cancer Res 2004;10:5930-5939
    • (2004) Clin Cancer Res , vol.10 , pp. 5930-5939
    • Chen, Z.1    Zhang, X.2    Li, M.3    Wang, Z.4    Wieand, H.S.5    Grandis, J.R.6    Shin, D.M.7
  • 83
    • 24644507378 scopus 로고    scopus 로고
    • Targeting cancer cells - more pathways, more inhibitors, more trails
    • Highlights of 9th annual Drug Discovery Technology World Congress; August 8-13, 2004; Boston, Massachusetts
    • Mariani SM. Targeting cancer cells - more pathways, more inhibitors, more trails. Highlights of 9th annual Drug Discovery Technology World Congress; August 8-13, 2004; Boston, Massachusetts. Med Gen Med 2004;6:22
    • (2004) Med Gen Med , vol.6 , pp. 22
    • Mariani, S.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.