Hypothalamic neuropeptides, not leptin sensitivity, contributes to the hyperphagia in lactating Brandt's voles, Lasiopodomys brandtii

Journal of Experimental Biology

Volumn 214, Issue 13, 2011, Pages 2242-2247

  Cui, Jian Guo ^a,b   Tang, Gang Bing ^a   Wang, De Hua ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b CHENGDU INSTITUTE OF BIOLOGY   (China)

Author keywords

Brandt's vole; Hyperphagia; Lactation; Lasiopodomys brandtii; Leptin; Neuropeptide; Ob Rb; SOCS 3; Suppressor of cytokine signalling 3

Indexed keywords

LEPTIN; MESSENGER RNA; NEUROPEPTIDE; PRIMER DNA; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL; ARTICLE; ARVICOLINAE; BLOOD; BODY COMPOSITION; BREEDING; CHEMISTRY; FEMALE; GENETICS; HYPERPHAGIA; HYPOTHALAMUS; LACTATION; METABOLISM; PREGNANCY;

ANIMALS; ARVICOLINAE; BODY COMPOSITION; DNA PRIMERS; FEMALE; HYPERPHAGIA; HYPOTHALAMUS; LACTATION; LEPTIN; NEUROPEPTIDES; PREGNANCY; PREGNANCY, ANIMAL; RNA, MESSENGER; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

AGOUTI; LASIOPODOMYS BRANDTII; MURIDAE;

EID: 79958791503     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.054056     Document Type: Article

References (44)

1. Ahima, R. S., Saper, C. B., Flier, J. S. and Elmquist, J. K. (2000). Leptin regulation of neuroendocrine systems. Front. Neuroendocrinol. 21, 263-307. (Pubitemid 30495784)
2. Anderson, G. M., Beijer, P., Bang, A. S., Fenwick, M. A., Bunn, S. J. and Grattan, D. R. (2006). Suppression of prolactin-induced signal transducer and activator of transcription 5b signaling and induction of suppressors of cytokine signaling messenger ribonucleic acid in the hypothalamic arcuate nucleus of the rat during late pregnancy and lactation. Endocrinology 147, 4996-5005. (Pubitemid 44402207)
3. Banks, A. S., Davis, S. M., Bates, S. H. and Myers, M. G., Jr (2000). Activation of downstream signals by the long form of the leptin receptor. J. Biol. Chem. 275, 14563-14572. (Pubitemid 30339746)
4. Barber, M. C., Clegg, R. A., Travers, M. T. and Vernon, R. G. (1997). Lipid metabolism in the lactating mammary gland. Biochim. Biophys. Acta. 1347, 101-126. (Pubitemid 27368104)
5. Bjørbæk, C., Lavery, H. J., Bates, S. H., Olson, R. K., Davis, S. M., Flier, J. S. and Myers, M. G., Jr (2000). SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985. J. Biol. Chem. 275, 40649-40657. (Pubitemid 32064706)
6. Bruckdorfer, K. R., Kang, S. S., Khan, I. H., Bourne, A. R. and Yudkin, J. (1974). Diurnal changes in the concentrations of plasma lipids, sugars, insulin and corticosterone in rats fed diets containing various carbohydrates. Horm. Metab. Res. 6, 99-106.
7. Chen, P., Li, C., Haskell-Luevano, C., Cone, R. D. and Smith, M. S. (1999). Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation. Endocrinology 140, 2645-2650. (Pubitemid 32245143)
8. Crowley, W. R., Ramoz, G., Torto, R. and Kalra, S. P. (2004). Role of leptin in orexigenic neuropeptide expression during lactation in rats. J. Neuroendocrinol. 16, 637-644. (Pubitemid 39029097)
9. Cui, J. G., Tang, G. B., Speakman, J. R. and Wang, D. H. (2011). Effects of leptin infusion during peak lactation on food intake, body composition, litter growth and maternal neuroendocrine status in female Brandt's voles (Lasiopodomys brandtii). Am. J. Physiol. Regul. Integr. Comp. Physiol. 300, R447-R459.
10. Denis, R. G., Williams, G. and Vernon, R. G. (2003a). Regulation of serum leptin and its role in the hyperphagia of lactation in the rat. J. Endocrinol. 176, 193-203. (Pubitemid 36284812)
11. Denis, R. G., Bing, C., Naderali, E. K., Vernon, R. G. and Williams, G. (2003b). Lactation modulates diurnal expression profiles of specific leptin receptor isoforms in the rat hypothalamus. J. Endocrinol. 178, 225-232. (Pubitemid 37063064)
12. El-Haschimi, K., Pierroz, D. D., Hileman, S. M., Bjorbaek, C. and Flier, J. S. (2000). Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J. Clin. Invest. 105, 1827-1832. (Pubitemid 30421764)
13. Flint, D. J. and Vernon, R. G. (1998). Effects of food restriction on the responses of the mammary gland and adipose tissue to prolactin and growth hormone in the lactating rat. J. Endocrinol. 156, 299-305. (Pubitemid 28105819)
14. Friedman, J. M. and Halaas, J. L. (1998). Leptin and the regulation of body weight in mammals. Nature 395, 763-770. (Pubitemid 28485436)
15. Howard, J. K., Cave, B. J., Oksanen, L. J., Tzameli, I., Bjorbaek, C. and Flier, J. S. (2004). Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3. Nat. Med. 10, 734-738. (Pubitemid 38937639)
16. Kawai, M., Yamaguchi, M., Murakami, T., Shima, K., Murata, Y. and Kishi, K. (1997). The placenta is not the main source of leptin production in pregnant rat: gestational profile of leptin in plasma and adipose tissues. Biochem. Biophys. Res. Commun. 240, 798-802. (Pubitemid 28271800)
17. Król, E., Duncan, J. S., Redman, P., Morgan, P. L., Mercer, J. G. and Speakman, J. R. (2006). Photoperiod regulates leptin sensitivity in field voles, Microtus agrestis. J. Comp. Physiol. B 176, 153-163. (Pubitemid 43155408)
18. Ladyman, S. R. (2008). Leptin resistance during pregnancy in the rat. J. Neuroendocrinol. 20, 269-277. (Pubitemid 351147014)
19. Ladyman, S. R. and Grattan, D. R. (2004). Region-specific reduction in leptin-induced phosphorylation of signal transducer and activator of transcription-3 (STAT3) in the rat hypothalamus is associated with leptin resistance during pregnancy. Endocrinology 145, 3704-3711. (Pubitemid 39037556)
20. Li, X. S. and Wang, D. H. (2005a). Suppression of thermogenic capacity during reproduction in primiparous Brandt's voles (Microtus brandtii). J. Therm. Biol. 30, 431-436.
21. Li, X. S. and Wang, D. H. (2005b). Regulation of body weight and thermogenesis in seasonally acclimatized Brandt's voles (Microtus brandti). Horm. Behav. 48, 321-328.
22. Liu, H., Wang, D. H. and Wang, Z. W. (2002). Maximum metabolizable energy intake in the Mongolian gerbil (Meriones unguiculatus). J. Arid Environ. 52, 405-411. (Pubitemid 35426552)
23. Liu, H., Wang, D. H. and Wang, Z. W. (2003). Energy requirements during reproduction in female Brandt's voles (Microtus brandtii). J. Mammal. 84, 1410-1416. (Pubitemid 37514987)
24. Liu, Q.-S., Li, J.-Y. and Wang, D.-H. (2007). Ultradian rhythms and the nutritional importance of caecotrophy in captive Brandt's voles (Lasiopodomys brandtii). J. Comp. Physiol. B 177, 423-432. (Pubitemid 46625359)
25. Mori, H., Hanada, R., Hanada, T., Aki, D., Mashima, R., Nishinakamura, H., Torisu, T., Chien, K. R., Yasukawa, H. and Yoshimura, A. (2004). Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity. Nat. Med. 10, 739-743. (Pubitemid 38937640)
26. Munzberg, H., Flier, J. S. and Bjorbaek, C. (2004). Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology 145, 4880-4889. (Pubitemid 39551104)
27. Munzberg, H., Bjornholm, M., Bates, S. H. and Myers, M. G., Jr (2005). Leptin receptor action and mechanisms of leptin resistance. Cell. Mol. Life Sci. 62, 642-652.
28. Scarpace, P. J., Matheny, M., Zhang, Y., Tumer, N., Frase, C. D., Shek, E. W., Hong, B., Prima, V. and Zolotukhin, S. (2002). Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats. Neuropharmacology 42, 548-561. (Pubitemid 34304247)
29. Schneider, J. E. and Wade, G. N. (1987). Body composition, food intake, and brown fat thermogenesis in pregnant Djungarian hamsters. Am. J. Physiol. 253, R314-R320.
30. Schwartz, M. W., Woods, S. C., Porte, D., Jr, Seeley, R. J. and Baskin, D. G. (2000). Central nervous system control of food intake. Nature 404, 661-671. (Pubitemid 30205071)
31. Smith, M. S. (1993). Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat. Endocrinology 133, 1258-1265. (Pubitemid 23267780)
32. Smith, M. S. and Grove, K. L. (2002). Integration of the regulation of reproductive function and energy balance: lactation as a model. Front. Neuroendocrinol. 23, 225-256. (Pubitemid 34856514)
33. Song, Z. G. and Wang, D. H. (2003). Metabolism and thermoregulation in the striped hamster Cricetulus barabensis. J. Therm. Biol. 28, 509-514.
34. Szczepankiewicz, D., Wojciechowicz, T., Kaczmarek, P. and Nowak, K. W. (2006) Leptin and its receptors in the course of pregnancy in the rat. Int. J. Mol. Med. 17, 95-99.
35. Tang, G. B., Cui, J. G. and Wang, D. H. (2008). Hypothalamic suppressor of cytokine signalling 3 mRNA is elevated and pro-opiomelanocortin mRNA is reduced during pregnancy in Brandt's voles (Lasiopodomys brandtii). J. Neuroendocrinol. 20, 1038-1044.
36. Tang, G. B., Cui, J. G. and Wang, D. H. (2009). The role for hypoleptinemia in cold adaptation in Brandt's voles. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297, R1293-R1301.
37. Trayhurn, P. and Richard, D. (1985). Brown adipose tissue thermogenesis and the energetics of pregnancy and lactation in rodents. Biochem. Soc. Trans. 13, 826-828. (Pubitemid 15248548)
38. Tups, A., Ellis, C., Moar, K. M., Logie, T. J., Adam, C. L., Mercer, J. G. and Klingenspor, M. (2004). Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodopus sungorus, is reflected in arcuate nucleus SOCS-3 (suppressor of cytokine signaling) gene expression. Endocrinology 145, 1185-1193. (Pubitemid 38280999)
39. Tups, A., Barrett, P., Ross, A. W., Morgan, P. J., Klingenspor, M. and Mercer, J. G. (2006). The suppressor of cytokine signalling 3, SOCS3, may be one critical modulator of seasonal body weight changes in the Siberian hamster, Phodopus sungorus. J. Neuroendocrinol. 18, 139-145.
40. Wade, G. N. and Schneider, J. E. (1992). Metabolic fuels and reproduction in female mammals. Neurosci. Biobehav. Rev. 16, 235-272.
41. Woodside, B. (2007). Prolactin and the hyperphagia of lactation. Physiol. Behav. 91, 375-382. (Pubitemid 47016543)
42. Woodside, B., Abizaid, A. and Walker, C. (2000). Changes in leptin levels during lactation: implications for lactational hyperphagia and anovulation. Horm. Behav. 37, 353-365. (Pubitemid 30432354)
43. Xiao, X. Q., Grove, K. L., Lau, S. Y., McWeeney, S. and Smith, M. S. (2005) Deoxyribonucleic acid microarray analysis of gene expression pattern in the arcuate nucleus/ventromedial nucleus of hypothalamus during lactation. Endocrinology 146, 4391-4398. (Pubitemid 41324036)
44. Zhang, X. Y. and Wang, D. H. (2007). Thermogenesis, food intake and serum leptin in cold-exposed lactating Brandt's voles Lasiopodomys brandtii. J. Exp. Biol. 210 512-521.