A concise synthesis and antimicrobial activities of 3-polyamino-23,24- bisnorcholanes as steroid-polyamine conjugates

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 13, 2011, Pages 3861-3865

  Kim, Hong Seok ^a   Khan, Sharaf N ^a   Jadhav, Jyoti R ^a   Jeong, Ji Woong ^b   Jung, Kyungjin ^b   Kwak, Jin Hwan ^b  

^a Kyungpook National University   (South Korea)

^b Handong University   (South Korea)

Author keywords

Antimicrobial activity; Reductive amination; SAR; Steroid polyamine conjugate

Indexed keywords

AMINE; ANTIINFECTIVE AGENT; PETROMYZANONAMINE DISULFATE; POLYAMINE; SPERMIDINE; SPERMINE; SQUALAMINE; STEROID; TRODUSQUEMINE; UNCLASSIFIED DRUG;

ACINETOBACTER CALCOACETICUS; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS CEREUS; BACILLUS LICHENIFORMIS; BACILLUS SUBTILIS; BACTERIAL STRAIN; CITROBACTER FREUNDII; CITROBACTER KOSERI; CONJUGATE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENTEROBACTER CLOACAE; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; KLEBSIELLA AEROGENES; KLEBSIELLA PNEUMONIAE; MICROCOCCUS LUTEUS; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; MORGANELLA MORGANII; NONHUMAN; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STEREOCHEMISTRY;

ANTI-INFECTIVE AGENTS; CHOLANES; GRAM-POSITIVE BACTERIA; HUMANS; MICROBIAL SENSITIVITY TESTS; POLYAMINES; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 79958760217     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.05.048     Document Type: Article

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