A comprehensive evaluation of the toxicology of cigarette ingredients: Essential oils and resins

Inhalation Toxicology

Volumn 23, Issue SUPPL. 1, 2011, Pages 41-69

  Coggins, Christopher R E ^a   Edmiston, Jeffery S ^b   Jerome, Ann M ^b   Langston, Timothy B ^b   Sena, Erica J ^b   Smith, Donna C ^b   Oldham, Michael J ^b  

^a Carson Watts Consulting   (United States)

^b Research   (United States)

Author keywords

cigarette ingredients; essential oils and resins; in vitro in vivo toxicology; smoke chemistry

Indexed keywords

ALGAROBA; CARRAGEENAN; CHAMOMILE; CIGARETTE SMOKE; COTININE; ESSENTIAL OIL; GUAR GUM; NEUTRAL RED; NICOTINE; PEPPERMINT OIL; RESIN;

ANIMAL EXPERIMENT; ARTICLE; ATROPHY; BACTERIAL STRAIN; CHEMISTRY; CIGARETTE SMOKING; CYTOTOXICITY; FEMALE; INHALATION TEST; MALE; MUTAGENICITY; NONHUMAN; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; RAT; SALMONELLA; TOXICOLOGY; WEIGHT GAIN;

ADMINISTRATION, INHALATION; ANIMALS; BODY WEIGHT; CELL SURVIVAL; CELLS, CULTURED; EXCIPIENTS; FEMALE; FLAVORING AGENTS; MALE; OILS, VOLATILE; RATS; RATS, SPRAGUE-DAWLEY; RESINS, PLANT; SALMONELLA TYPHIMURIUM; SMOKE; SMOKING; TOBACCO; TOXICITY TESTS; XENOBIOTICS;

BACTERIA (MICROORGANISMS); CERATONIA SILIQUA; CYAMOPSIS TETRAGONOLOBA; MENTHA SPICATA; MENTHA X PIPERITA; NICOTIANA TABACUM; RATTUS; SALMONELLA;

EID: 79958754578     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2010.543188     Document Type: Article

References (11)

1. Baker RR, Massey ED, Smith G. 2004. An overview of the effects of tobacco ingredients on smoke chemistry and toxicity. Food Chem Toxicol 42(Suppl):S53-S83 (Pubitemid 38456980)
2. Carmines EL. 2002. Evaluation of the potential effects of ingredients added to cigarettes. Part 1: cigarette design, testing approach, and review of results. Food Chem Toxicol 40:77-91 (Pubitemid 33132143)
3. Gaworski CL, Dozier MM, Heck JD, Gerhart JM, Rajendran N, David RM, Brennecke LH, Morrissey R. 1998. Toxicologic evaluation of flavor ingredients added to cigarette tobacco: 13-week inhalation exposures in rats. Inhal Toxicol 10:357-381 (Pubitemid 28300757)
4. Gaworski CL, Oldham MJ, Coggins CR. 2010. Toxicological considerations on the use of propylene glycol as a humectant in cigarettes. Toxicology 269:54-66
5. Gaworski CL, Oldham MJ, Wagner K, Coggins CRE, Patskan GJ. 2011. A comprehensive evaluation of the toxicology of 95 ingredients added individually to experimental cigarettes: approach and methods. Inhal Toxicol, 23(S1):1-12
6. Ménache MG, Miller FJ, Raabe OG. 1995. Particle inhalability curves for humans and small laboratory animals. Ann Occup Hyg 39:317-328
7. NTP. 1989. Toxicology and carcinogenicity studies of d-carvone (CAS No. 2244-16-8) in B6C3F1 mice and toxicology studies in F344/ Nrates (gavage studies). Draft report submitted to WHO by Flavor and Extract Manufacturer's Association of the United States, Washington, DC. National Toxicology Program (NTP), Report Number:NTP/TR No.381, Draft; NIH No.90-2836
8. Patskan GJ, Podraza KF, Meurrens K, Coggins CR, Friedrichs B, Gerstenberg B, Gomm W, Schnell P, Stabbert R, Veltel D, Weber S, Terpstra P. 2008. Toxicological comparisons of three styles of a commercial U.S. cigarette (Marlboro with the 1R4F reference cigarette. Inhal Toxicol 20:695-721 (Pubitemid 351882934)
9. Raabe OG, Al-Bayati MA, Teague SV, Rasolt A. 1988. Regional deposition of inhaled monodisperse coarse and fine aerosol particles in small laboratory animals. Ann Occup Hyg 32:53-63
10. Renne RA, Yoshimura H, Yoshino K, Lulham G, Minamisawa S, Tribukait A, Dietz DD, Lee KM, Westerberg RB. 2006. Effects of flavoring and casing ingredients on the toxicity of mainstream cigarette smoke in rats. Inhal Toxicol 18:685-706 (Pubitemid 44178424)
11. Rodgman A, Perfetti TA. 2009. The chemical components of tobacco and tobacco smoke. Boca Raton, FL: CRC Press