Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: A [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme

Journal of Biological Chemistry

Volumn 286, Issue 24, 2011, Pages 21287-21294

  Zhang, Qi ^a   Chen, Dandan ^a,b   Lin, Jun ^c   Liao, Rijing ^a   Tong, Wei ^d   Xu, Zhinan ^b   Liu, Wen ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c SHANGHAI INSTITUTE OF APPLIED PHYSICS   (China)

^d INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORBANCES; CARBON CHAINS; COMPLEX REACTIONS; ENZYME SUPERFAMILIES; EPR STUDIES; MUTATIONAL ANALYSIS; NON-SPECIFIC INTERACTIONS; S-ADENOSYLMETHIONINE; SYNTHASES; THIOPEPTIDE; UV-VISIBLE; VERY LOW TEMPERATURES;

BIOCHEMISTRY; BIOSYNTHESIS; CATALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; SPECTROSCOPIC ANALYSIS;

ENZYMES;

3 METHYL 2 INDOLIC ACID; PROTEIN NOCL; S ADENOSYLMETHIONINE; THIOPEPTIDE NOCATHIACIN; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ARTICLE; CATALYSIS; CLUSTER ANALYSIS; ELECTRON SPIN RESONANCE; ENZYME SUBSTRATE COMPLEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW TEMPERATURE; MASS SPECTROMETRY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOPHILICITY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; SEQUENCE ALIGNMENT; STEADY STATE;

AMINO ACID SEQUENCE; CATALYSIS; DNA MUTATIONAL ANALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; FREE RADICALS; IRON-SULFUR PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDES; S-ADENOSYLMETHIONINE; SPECTROPHOTOMETRY, ULTRAVIOLET; TRYPTOPHAN;

EID: 79958752675     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.224832     Document Type: Article

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