Radical S-adenosylmethionine enzyme coproporphyrinogen III oxidase HemN: Functional features of the [4Fe-4S] cluster and the two bound S-adenosyl-L-methionines

Journal of Biological Chemistry

Volumn 280, Issue 32, 2005, Pages 29038-29046

  Layer, Gunhild ^a,d   Grage, Katrin ^a   Teschner, Thomas ^b   Schünemann, Volker ^b,e   Breckau, Daniela ^a   Masoumi, Ava ^a   Jahn, Martina ^a   Heathcote, Peter ^c   Trautwein, Alfred X ^b   Jahn, Dieter ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d CEA GRENOBLE   (France)

^e Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CONFORMATIONS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; OXIDATION; SUBSTRATES;

CLEAVAGE; CLUSTERS; CO-SUBSTRATE; COORDINATION SITES;

ENZYMES;

COPROPORPHYRINOGEN OXIDASE; COPROPORPHYRINOGEN OXIDASE HEMN; IRON SULFUR PROTEIN; PROTOPHORPHYRINOGEN 9; PROTOPORPHYRINOGEN OXIDASE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; DECARBOXYLATION; ELECTRON SPIN RESONANCE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HEME SYNTHESIS; ISOMER; MOSSBAUER SPECTROSCOPY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; WILD TYPE;

BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; CELL-FREE SYSTEM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; COPROPORPHYRINOGEN OXIDASE; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; FREE RADICALS; IRON; IRON-SULFUR PROTEINS; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PROTEIN BINDING; PROTOPORPHYRINOGEN OXIDASE; RECOMBINANT PROTEINS; S-ADENOSYLMETHIONINE; SPECTROPHOTOMETRY; SPECTROSCOPY, MOSSBAUER; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TIME FACTORS;

ESCHERICHIA COLI;

EID: 23844452716     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501275200     Document Type: Article

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