Adenosine derived from Staphylococcus aureus-engulfed macrophages functions as a potent stimulant for the induction of inflammatory cytokines in mast cells

BMB Reports

Volumn 44, Issue 5, 2011, Pages 335-340

  Ma, Ying Jie ^a,c   Kim, Chan Hee ^a   Ryu, Kyoung Hwa ^a   Kim, Min Su ^a   So, Young In ^a   Lee, Kong Joo ^b   Garred, Peter ^c   Lee, Bok Luel ^a  

^a Pusan National University   (South Korea)

^b Ewha Womans University   (South Korea)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Adenosine; Innate immunity; Mast cell; PAMP; Phagocytosis; Staphylococcus aureus

Indexed keywords

ADENOSINE; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; CYTOLOGY; HUMAN; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; MAST CELL; METABOLISM; MOUSE; PHAGOCYTOSIS; PHYSIOLOGY; STAPHYLOCOCCUS AUREUS;

ADENOSINE; ANIMALS; CELL LINE; CYTOKINES; HUMANS; INFLAMMATION; INTERLEUKIN-6; INTERLEUKIN-8; MACROPHAGES; MAST CELLS; MICE; MICE, INBRED C57BL; PHAGOCYTOSIS; PURINERGIC P1 RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P1; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); MURINAE; STAPHYLOCOCCUS AUREUS;

EID: 79958729117     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2011.44.5.335     Document Type: Article

References (18)

1. Medzhitov, R. and Janeway, C. A. Jr. (1997) Innate immunity: the virtues of a nonclonal system of recognition. Cell 91, 295-298.
2. Hoffmann, J. A., Kafatos, F. C., Janeway, C. A. and Ezekowitz, R. A. (1999) Phylogenetic perspectives in innate immunity. Science 284, 1313-1318.
3. Janeway, C. A. and Medzhitov, R. Jr. (2002) Innate immune recognition. Annu. Rev. Immunol. 20, 197-216.
4. Akira, S., Uematsu, S. and Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124, 783-801.
5. Trincavelli, M. L., Daniele, S. and Martini, C. (2010) Adenosine receptors: what we know and what we are learning. Curr. Top. Med. Chem. 10, 860-877.
6. Spicuzza, L., Bonfiglio, C. and Polosa, R. (2003) Research applications and implications of adenosine in diseased airways. Trends. Pharmacol. Sci. 24, 409-413.
7. Kumar, V. and Sharma, A. (2009) Adenosine: an endogenous modulator of innate immune system with therapeutic potential. Eur. J. Pharmacol. 616, 7-15.
8. Olah, M. E. and Stiles, G. L. (1995) Adenosine receptor subtypes: characterization and therapeutic regulation. Annu. Rev. Pharmacol. Toxicol. 35, 581-606.
9. Zhong, H., Shlykov, S. G., Molina, J. G., Sanborn, B. M., Jacobson, M. A., Tilley, S. L. and Blackburn, M. R. (2003) Activation of murine lung mast cells by the adenosine A3 receptor. J. Immunol. 171, 338-345.
10. Fredholm, B. B. and Dunwiddie, T. V. (1988) How does adenosine inhibit transmitter release? Trends. Pharmacol. Sci. 9, 130-134.
11. Fournier, B. and Philpott, D. J. (2005) Recognition of Staphylococcus aureus by the innate immune system. Clin. Microbiol. Rev. 18, 521-540.
12. Sommerschild, H. T., Lunde, P. K., Deindl, E., Jynge, P., Ilebekk, A. and Kirkeboen, K. A. (1999) Elevated levels of endogenous adenosine alter metabolism and enhance reduction in contractile function during low-flow ischemia: associated changes in expression of Ca(2+)-ATPase and phospholamban. J. Mol. Cell Cardiol. 31, 1897-1911.
13. Peschel, A., Jack, R. W., Otto, M., Collins, L. V., Staubitz, P., Nicholson, G., Kalbacher, H., Nieuwenhuizen, W. F., Jung, G., Tarkowski, A., van Kessel, K. P. and van Strijp, J. A. (2001) Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with L-lysine. J. Exp. Med. 193, 1067-1076.
14. Park, K. H., Kurokawa, K., Zheng, L., Jung, D. J., Tateishi, K., Jin, J. O., Ha, N. C., Kang, H. J., Matsushita, M., Kwak, J. Y., Takahashi, K. and Lee, B. L. (2010) Human Serum Mannose-binding Lectin Senses Wall Teichoic Acid Glycopolymer of Staphylococcus aureus, Which Is Restricted in Infancy. J. Biol. Chem. 285, 27167-27175.
15. Kurokawa, K., Lee, H., Roh, K. B., Asanuma, M., Kim, Y. S., Nakayama, H., Shiratsuchi, A., Choi, Y., Takeuchi, O., Kang, H. J., Dohmae, N., Nakanishi, Y., Akira, S., Sekimizu, K. and Lee, B. L. (2009) The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2. J. Biol. Chem. 284, 8406-8411.
16. Ohta, A. and Sitkovsky, M. (2001) Role of G-proteincoupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 414, 916-920.
17. Peralta, C., Hotter, G., Closa, D., Prats, N., Xaus, C., Gelpi, E. and Rosello-Catafau, J. (1999) The protective role of adenosine in inducing nitric oxide synthesis in rat liver ischemia preconditioning is mediated by activation of adenosine A2 receptors. Hepatology 29, 126-132.
18. Zhu, F. G., Gomi, K. and Marshall, J. S. (1998) Short-term and long-term cytokine release by mouse bone marrow mast cells and the differentiated KU-812 cell line are inhibited by brefeldin A. J. Immunol. 161, 2541-2551.