메뉴 건너뛰기




Volumn 44, Issue 5, 2011, Pages 312-316

Knockdown of cytosolic NADP+-dependent isocitrate dehydrogenase enhances MPP+-induced oxidative injury in PC12 cells

Author keywords

Antioxidant enzyme; MPP+; Parkinson's disease; Redox status; SiRNA

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ISOCITRATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMALL INTERFERING RNA;

EID: 79958695680     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2011.44.5.312     Document Type: Article
Times cited : (6)

References (23)
  • 3
    • 0030007912 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease and other neurodigenerative disorders
    • Jenner, P. (1996) Oxidative stress in Parkinson's disease and other neurodigenerative disorders. Pathol. Biol. 44, 57-64.
    • (1996) Pathol. Biol. , vol.44 , pp. 57-64
    • Jenner, P.1
  • 5
    • 0026704075 scopus 로고
    • Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group
    • Dexter, D. T., Jenner, P., Schapira, A. H. and Marsden, C. D. (1992) Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Annu. Neurol. 32, S94-S100.
    • (1992) Annu. Neurol. , vol.32
    • Dexter, D.T.1    Jenner, P.2    Schapira, A.H.3    Marsden, C.D.4
  • 6
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
    • Tipton, K. F. and Singer, T. P. (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J. Neurochem. 61, 1191-1206.
    • (1993) J. Neurochem. , vol.61 , pp. 1191-1206
    • Tipton, K.F.1    Singer, T.P.2
  • 7
    • 0031036391 scopus 로고    scopus 로고
    • Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice
    • Sriram, K., Pai, K. S., Boyd, M. R. and Ravindranath, V. (1997) Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice. Brain Res. 749, 44-52.
    • (1997) Brain Res , vol.749 , pp. 44-52
    • Sriram, K.1    Pai, K.S.2    Boyd, M.R.3    Ravindranath, V.4
  • 8
    • 0022651251 scopus 로고
    • 1-Methyl-4-phenylpyridine (MPP+) induces oxidative stress in the rodent
    • Johannessen, J. N., Adams, J. N., Schuller, H. M., Bacon, J. P. and Markey, S. P. (1986) 1-Methyl-4-phenylpyridine (MPP+) induces oxidative stress in the rodent. Life. Sci. 38, 743-749.
    • (1986) Life. Sci. , vol.38 , pp. 743-749
    • Johannessen, J.N.1    Adams, J.N.2    Schuller, H.M.3    Bacon, J.P.4    Markey, S.P.5
  • 9
    • 0027304263 scopus 로고
    • Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Zang, L. Y. and Misra, H. P. (1993) Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Biol. Chem. 268, 16504-16512.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16504-16512
    • Zang, L.Y.1    Misra, H.P.2
  • 11
    • 0034912851 scopus 로고    scopus 로고
    • NAD(P)H, a directly operating antioxidant?
    • Kirsch, M. and de Groot, H. (2001) NAD(P)H, a directly operating antioxidant?, FASEB J. 15, 1569-1574.
    • (2001) FASEB J , vol.15 , pp. 1569-1574
    • Kirsch, M.1    de Groot, H.2
  • 12
    • 17644395645 scopus 로고    scopus 로고
    • Thioredoxin and its related molecules: update 2005
    • Nakamura, H. (2005) Thioredoxin and its related molecules: update 2005. Antioxid. Redox Signal. 7, 823-828.
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 823-828
    • Nakamura, H.1
  • 14
    • 0014621744 scopus 로고
    • The redox state of free nicotinamide-adenine dinucleotide phosphate in the cytoplasm of rat liver
    • Veech, R. L., Eggleston, L. V. and Krebs, H. A. (1969) The redox state of free nicotinamide-adenine dinucleotide phosphate in the cytoplasm of rat liver. Biochem. J. 115, 609-619.
    • (1969) Biochem. J. , vol.115 , pp. 609-619
    • Veech, R.L.1    Eggleston, L.V.2    Krebs, H.A.3
  • 15
    • 0036614971 scopus 로고    scopus 로고
    • Cytosolic NADP+-dependent isocitrate dehydrogenase status modulates oxidative damage to cells
    • Lee, S. M., Koh, H. J., Park, D. C., Song, B. J., Huh, T. L. and Park, J. W. (2002) Cytosolic NADP+-dependent isocitrate dehydrogenase status modulates oxidative damage to cells. Free Radic. Biol. Med. 32, 1185-1196.
    • (2002) Free Radic. Biol. Med , vol.32 , pp. 1185-1196
    • Lee, S.M.1    Koh, H.J.2    Park, D.C.3    Song, B.J.4    Huh, T.L.5    Park, J.W.6
  • 16
    • 60349131558 scopus 로고    scopus 로고
    • +)- dependent isocitrate dehydrogenase by small interfering RNA enhances the sensitivity of HeLa cells toward staurosporine
    • +)- dependent isocitrate dehydrogenase by small interfering RNA enhances the sensitivity of HeLa cells toward staurosporine. Free Rad. Res. 43, 165-173.
    • (2009) Free Rad. Res. , vol.43 , pp. 165-173
    • Lee, S.M.1    Park, S.Y.2    Shin, S.W.3    Kil, I.S.4    Yang, E.S.5    Park, J.W.6
  • 17
    • 77449115641 scopus 로고    scopus 로고
    • +)-dependent isocitrate dehydrogenase regulates cadmium-induced apoptosis
    • +)-dependent isocitrate dehydrogenase regulates cadmium-induced apoptosis. Biochem. Pharmacol. 79, 72-80.
    • (2010) Biochem. Pharmacol , vol.79 , pp. 72-80
    • Shin, S.W.1    Kil, I.S.2    Park, J.W.3
  • 18
    • 0035684389 scopus 로고    scopus 로고
    • +-dependent isocitrate dehydrogenase by reactive oxygen species
    • Lee, S. M., Huh, T. L. and Park, J. W. (2001) Inactivation of NADP+-dependent isocitrate dehydrogenase by reactive oxygen species. Biochimie 83, 1057-1065.
    • (2001) Biochimie , vol.83 , pp. 1057-1065
    • Lee, S.M.1    Huh, T.L.2    Park, J.W.3
  • 19
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. and Tuschl, T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 20
    • 4344560924 scopus 로고    scopus 로고
    • The use of N-t-butyl hydroxylamine for radioprotection in cultured cells and mice
    • Lee, J. H., Kim, I. S. and Park, J. W. (2004) The use of N-t-butyl hydroxylamine for radioprotection in cultured cells and mice. Carcinogenesis 25, 1435-1442.
    • (2004) Carcinogenesis , vol.25 , pp. 1435-1442
    • Lee, J.H.1    Kim, I.S.2    Park, J.W.3
  • 21
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer, H., Schaur, R. J. and Zollner, H. (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11, 81-128.
    • (1991) Free Radic. Biol. Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.