The influence of physical activity on cardiometabolic biomarkers in youths: A review

Pediatric Exercise Science

Volumn 23, Issue 2, 2011, Pages 169-185

  Gutin, Bernard ^a,b,c,d   Owens, Scott ^e  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b IL   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

BODY MASS; CARDIOVASCULAR SYSTEM; CHILD; CHILD WELFARE; HEALTH PROMOTION; HEALTH STATUS; HUMAN; LIFESTYLE; METABOLISM; MOTOR ACTIVITY; OBESITY; PUBLIC HEALTH; REVIEW;

ADIPOSITY; BIOLOGICAL MARKERS; BODY MASS INDEX; CARDIOVASCULAR SYSTEM; CHILD; CHILD WELFARE; HEALTH PROMOTION; HEALTH STATUS; HUMANS; LIFE STYLE; MOTOR ACTIVITY; PUBLIC HEALTH;

EID: 79958289491     PISSN: 08998493     EISSN: 15432920     Source Type: Journal    
DOI: 10.1123/pes.23.2.169     Document Type: Review

References (58)

1. Andersen, L.B., M. Harro, L.B. Sardinha, et al. Physical activity and clustered cardiovascular risk in children: A cross-sectional study (The European Youth Heart Study). Lancet. 368:299-304, 2006. (Pubitemid 44067246)
2. Andersen, L.B., L.B. Sardinha, K. Froberg, C.J. Riddoch, A.S. Page, and S.A. Anderssen. Fitness, fatness and clustering of cardiovascular risk factors in children from Denmark, Estonia and Portugal: The European Youth Heart Study. Int. J. Pediatr. Obes. 3(Suppl. 1):58-66, 2008. (Pubitemid 351285469)
3. Balagopal, P., D. George, N. Patton, et al. Lifestyle-only intervention attenuates the inflammatory state associated with obesity: A randomized controlled study in adolescents. J. Pediatr. 146:342-348, 2005. (Pubitemid 40341743)
4. Barbeau, P., M.H. Johnson, C.A. Howe, et al. Ten months of exercise improves general and visceral adiposity, bone, and fitness in black girls. Obesity (Silver Spring). 15:2077-2085, 2007. (Pubitemid 47402240)
5. Benson, A.C., M.E. Torode, and M.A. Fiatarone Singh. The effect of high-intensity progressive resistance training on adiposity in children: A randomized controlled trial. Int J Obes (Lond). 32:1016-1027, 2008. (Pubitemid 351986231)
6. Benson, A.C., M.E. Torode, and M.A. Singh. Muscular strength and cardiorespiratory fitness is associated with higher insulin sensitivity in children and adolescents. Int. J. Pediatr. Obes. 1:222-231, 2006.
7. Boreham, C., J. Twisk, C. Neville, M. Savage, L. Murray, and A. Gallagher. Associations between physical fitness and activity patterns during adolescence and cardiovascular risk factors in young adulthood: The Northern Ireland Young Hearts Project. Int. J. Sports Med. 23(Suppl. 1):S22-S26, 2002. (Pubitemid 34564442)
8. Boreham, C.A., I. Ferreira, J.W. Twisk, A.M. Gallagher, M.J. Savage, and L.J. Murray. Cardiorespiratory fitness, physical activity, and arterial stiffness: The Northern Ireland Young Hearts Project. Hypertension. 44:721-726, 2004. (Pubitemid 39435244)
9. Brage, S., N. Wedderkopp, U. Ekelund, et al. Features of the metabolic syndrome are associated with objectively measured physical activity and fitness in Danish children: The European Youth Heart Study (EYHS). Diabetes Care. 27:2141-2148, 2004. (Pubitemid 39167176)
10. Bunt, J.C., A.D. Salbe, I.T. Harper, R.L. Hanson, and P.A. Tataranni. Weight, adiposity, and physical activity as determinants of an insulin sensitivity index in pima Indian children. Diabetes Care. 26:2524-2530, 2003. (Pubitemid 37052095)
11. Carrel, A.L., R.R. Clark, S. Peterson, J. Eickhoff, and D.B. Allen. School-based fitness changes are lost during the summer vacation. Arch. Pediatr. Adolesc. Med. 161:561-564, 2007. (Pubitemid 46878681)
12. Carrel, A.L., R.R. Clark, S.E. Peterson, B.A. Nemeth, J. Sullivan, and D.B. Allen. Improvement of fitness, body composition, and insulin sensitivity in overweight children in a school-based exercise program: A randomized, controlled study. Arch. Pediatr. Adolesc. Med. 159:963-968, 2005. (Pubitemid 41423336)
13. Corvalan, C., R. Uauy, J. Kain, and R. Martorell. Obesity indicators and cardiometabolic status in 4-y-old children. Am. J. Clin. Nutr. 91:166-174, 2010.
14. Craig, S.B., L.G. Bandini, A.H. Lichtenstein, E.J. Schaefer, and W.H. Dietz. The impact of physical activity on lipids, lipoproteins, and blood pressure in preadolescent girls. Pediatrics. 98:389-395, 1996. (Pubitemid 26295839)
15. Destefano, R.A., S. Caprio, J.T. Fahey, W.V. Tamborlane, and B. Goldberg. Changes in body composition after a 12-wk aerobic exercise program in obese boys. Pediatr. Diabetes. 1:61-65, 2000.
16. Eisenmann, J.C., P.T. Katzmarzyk, L. Perusse, C. Bouchard, and R.M. Malina. Estimated daily energy expenditure and blood lipids in adolescents: The Quebec Family Study. J. Adolesc. Health. 33:147-153, 2003. (Pubitemid 36999823)
17. Farpour-Lambert, N.J., Y. Aggoun, L.M. Marchand, X.E. Martin, F.R. Herrmann, and M. Beghetti. Physical activity reduces systemic blood pressure and improves early markers of atherosclerosis in pre-pubertal obese children. J. Am. Coll. Cardiol. 54:2396-2406, 2009.
18. Ferreira, I., J.W. Twisk, W. Van Mechelen, H.C. Kemper, and C.D. Stehouwer. Development of fatness, fitness, and lifestyle from adolescence to the age of 36 years: Determinants of the metabolic syndrome in young adults: The Amsterdam growth and health longitudinal study. Arch. Intern. Med. 165:42-48, 2005. (Pubitemid 40096080)
19. Field, A. Epidemiology of health and economic consequences of pediatric obesity. In:Handbook of Pediatric Obesity, M. Goran and M. Sothern (Eds.). Boca Raton, FL: CRC Press, 2006.
20. Gidding, S.S., B.A. Barton, J.A. Dorgan, et al. Higher self-reported physical activity is associated with lower systolic blood pressure: The Dietary Intervention Study in Childhood (DISC). Pediatrics. 118:2388-2393, 2006. (Pubitemid 46397578)
21. Goodman, E., L.M. Dolan, J.A. Morrison, and S.R. Daniels. Factor analysis of clustered cardiovascular risks in adolescence: Obesity is the predominant correlate of risk among youth. Circulation. 111:1970-1977, 2005. (Pubitemid 40570217)
22. Gutin, B. Diet vs exercise for the prevention of pediatric obesity: The role of exercise. Int J Obes advance online publication doi: Ijo 2010 140 [pii 10.1038/ijo.2010.140, 2010.
23. Gutin, B., P. Barbeau, M.S. Litaker, M. Ferguson, and S. Owens. Heart rate variability in obese children: Relations to total body and visceral adiposity, and changes with physical training and detraining. Obes. Res. 8:12-19, 2000.
24. Gutin, B., P. Barbeau, S. Owens, et al. Effects of exercise intensity on cardiovascular fitness, total body composition, and visceral adiposity of obese adolescents. Am. J. Clin. Nutr. 75:818-826, 2002. (Pubitemid 34441249)
25. Gutin, B., C. Howe, M.H. Johnson, M.C. Humphries, H. Snieder, and P. Barbeau. Heart rate variability in adolescents: Relations to physical activity, fitness, and adiposity. Med. Sci. Sports Exerc. 37:1856-1863, 2005. (Pubitemid 41691826)
26. Gutin, B., M.H. Johnson, M.C. Humphries, et al. Relationship of visceral adiposity to cardiovascular disease risk factors in black and white teens. Obesity (Silver Spring). 15:1029-1035, 2007. (Pubitemid 46740979)
27. Gutin, B., Z. Yin, M.C. Humphries, and P. Barbeau. Relations of moderate and vigorous physical activity to fitness and fatness in adolescents. Am. J. Clin. Nutr. 81:746-750, 2005. (Pubitemid 41724979)
28. Gutin, B., Z. Yin, M.C. Humphries, et al. Relations of body fatness and cardiovascular fitness to lipid profile in black and white adolescents. Pediatr. Res. 58:78-82, 2005. (Pubitemid 40967433)
29. Gutin, B., Z. Yin, M.C. Humphries, W.H. Hoffman, B. Gower, and P. Barbeau. Relations of fatness and fitness to fasting insulin in black and white adolescents. J. Pediatr. 145:737-743, 2004. (Pubitemid 39586609)
30. Gutin, B., Z. Yin, M. Johnson, and P. Barbeau. Preliminary findings of the effect of a 3-year after-school physical activity intervention on fitness and body fat: The Medical College of Georgia Fitkid Project. Int. J. Pediatr. Obes. 3(Suppl. 1):3-9, 2008. (Pubitemid 351285461)
31. Hoene, M., R. Lehmann, A.M. Hennige, et al. Acute regulation of metabolic genes and insulin receptor substrates in the liver of mice by one single bout of treadmill exercise. J. Physiol. 587:241-252, 2009.
32. Hopkins, N.D., G. Stratton, T.M. Tinken, et al. Relationships between measures of fitness, physical activity, body composition and vascular function in children. Atherosclerosis. 204:244-249, 2009.
33. Humphries, M.C., B. Gutin, P. Barbeau, S. Vemulapalli, J. Allison, and S. Owens. Relations of adiposity and effects of training on the left ventricle in obese youths. Med. Sci. Sports Exerc. 34:1428-1435, 2002. (Pubitemid 35006813)
34. Hussey, J., C. Bell, K. Bennett, J. O'Dwyer, and J. Gormley. Relationship between the intensity of physical activity, inactivity, cardiorespiratory fitness and body composition in 7-10-year-old Dublin children. Br. J. Sports Med. 41:311-316, 2007. (Pubitemid 46698369)
35. Imperatore, G., Y.J. Cheng, D.E. Williams, J. Fulton, and E.W. Gregg. Physical activity, cardiovascular fitness, and insulin sensitivity among U.S. adolescents: The National Health and Nutrition Examination Survey, 1999-2002. Diabetes Care. 29:1567-1572, 2006. (Pubitemid 44127582)
36. Janssen, I., and A.G. Leblanc. Systematic review of the health benefits of physical activity and fitness in school-aged children and youth. Int. J. Behav. Nutr. Phys. Act. 7:40, 2010.
37. Kang, H.S., B. Gutin, P. Barbeau, et al. Physical training improves insulin resistance syndrome markers in obese adolescents. Med. Sci. Sports Exerc. 34:1920-1927, 2002. (Pubitemid 35440411)
38. Kasa-Vubu, J.Z. Metformin as a weight-loss tool in "at-risk" obese adolescents: A magic bullet? J. Pediatr. 152:750-752, 2008. (Pubitemid 351680266)
39. Kelly, A.S., R.J. Wetzsteon, D.R. Kaiser, J. Steinberger, A.J. Bank, and D.R. Dengel. Inflammation, insulin, and endothelial function in overweight children and adolescents: The role of exercise. J. Pediatr. 145:731-736, 2004. (Pubitemid 39586608)
40. Krekoukia, M., G.P. Nassis, G. Psarra, K. Skenderi, G.P. Chrousos, and L.S. Sidossis. Elevated total and central adiposity and low physical activity are associated with insulin resistance in children. Metabolism. 56:206-213, 2007. (Pubitemid 46074067)
41. Luu, Y.K., E. Capilla, C.J. Rosen, et al. Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietaryinduced obesity. J. Bone Miner. Res. 24:50-61, 2009.
42. Mathai, A.S., A. Bonen, C.R. Benton, D.L. Robinson, and T.E. Graham. Rapid exerciseinduced changes in PGC-1alpha mRNA and protein in human skeletal muscle. J. Appl. Physiol. 105:1098-1105, 2008.
43. Meyer, A.A., G. Kundt, U. Lenschow, P. Schuff-Werner, and W. Kienast. Improvement of early vascular changes and cardiovascular risk factors in obese children after a sixmonth exercise program. J. Am. Coll. Cardiol. 48:1865-1870, 2006. (Pubitemid 44648607)
44. Ondrak, K.S., R.G. McMurray, S.I. Bangdiwala, and J.S. Harrell. Influence of aerobic power and percent body fat on cardiovascular disease risk in youth. J. Adolesc. Health. 41:146-152, 2007. (Pubitemid 47058980)
45. Owens, S., B. Gutin, J. Allison, et al. Effect of physical training on total and visceral fat in obese children. Med. Sci. Sports Exerc. 31:143-148, 1999. (Pubitemid 29036371)
46. Park, J.Y., P.Y. Wang, T. Matsumoto, et al. p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content. Circ Res. 105:705-712, 711 p following 712, 2009.
47. Patrick, K., G.J. Norman, K.J. Calfas, et al. Diet, physical activity, and sedentary behaviors as risk factors for overweight in adolescence. Arch. Pediatr. Adolesc. Med. 158:385-390, 2004. (Pubitemid 38451568)
48. Platat, C., A. Wagner, T. Klumpp, B. Schweitzer, and C. Simon. Relationships of physical activity with metabolic syndrome features and low-grade inflammation in adolescents. Diabetologia. 49:2078-2085, 2006. (Pubitemid 44168475)
49. Raghuveer, G. Lifetime cardiovascular risk of childhood obesity. Am. J. Clin. Nutr. 91:1514S-1519S, 2010.
50. Rubin, C.T., E. Capilla, Y.K. Luu, et al. Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals. Proc. Natl. Acad. Sci. USA. 104:17879-17884, 2007. (Pubitemid 350210928)
51. Ruiz, J.R., N.S. Rizzo, A. Hurtig-Wennlof, F.B. Ortega, J. Warnberg, and M. Sjostrom. Relations of total physical activity and intensity to fitness and fatness in children: The European Youth Heart Study. Am. J. Clin. Nutr. 84:299-303, 2006. (Pubitemid 44699137)
52. Schmitz, K.H., D.R. Jacobs, Jr., C.P. Hong, J. Steinberger, A. Moran, and A.R. Sinaiko. Association of physical activity with insulin sensitivity in children. Int. J. Obes. Relat. Metab. Disord. 26:1310-1316, 2002. (Pubitemid 35221877)
53. Stallmann-Jorgensen, I.S., B. Gutin, J.L. Hatfield-Laube, M.C. Humphries, M.H. Johnson, and P. Barbeau. General and visceral adiposity in black and white adolescents and their relation with reported physical activity and diet. Int J Obes (Lond). 31:622-629, 2007. (Pubitemid 46482364)
54. Stoedefalke, K., N. Armstrong, B.J. Kirby, and J.R. Welsman. Effect of training on peak oxygen uptake and blood lipids in 13 to 14-year-old girls. Acta Paediatr. 89:1290-1294, 2000.
55. Strong, W.B., R.M. Malina, C.J. Blimkie, et al. Evidence based physical activity for school-age youth. J. Pediatr. 146:732-737, 2005. (Pubitemid 40840591)
56. Wennlof, A.H., A. Yngve, T.K. Nilsson, and M. Sjostrom. Serum lipids, glucose and insulin levels in healthy schoolchildren aged 9 and 15 years from Central Sweden: Reference values in relation to biological, social and lifestyle factors. Scand. J. Clin. Lab. Invest. 65:65-76, 2005. (Pubitemid 40278313)
57. Yang, X., R. Telama, M. Hirvensalo, J.S. Viikari, and O.T. Raitakari. Sustained participation in youth sport decreases metabolic syndrome in adulthood. Int J Obes (Lond). 33:1219-1226, 2009.
58. Yin, Z., B. Gutin, M.H. Johnson, et al. An environmental approach to obesity prevention in children: Medical College of Georgia FitKid Project year 1 results. Obes. Res. 13:2153-2161, 2005.