Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity

Journal of Bone and Mineral Research

Volumn 24, Issue 1, 2009, Pages 50-61

  Yen, Kim Luu ^a   Capilla, Encarnacion ^b   Rosen, Clifford J ^c   Gilsanz, Vicente ^d   Pessin, Jeffrey E ^b   Judex, Stefan ^a   Rubin, Clinton T ^a  

^a St Francis Hospital The Heart Center   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c JACKSON LABORATORY   (United States)

^d CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

Adipocytes; Adipogenesis; Mechanical loading; Mesenchymal stem cells; Obesity; Osteoblastogenesis; Osteoblasts; Osteoporosis

Indexed keywords

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROL GROUP; CONTROLLED STUDY; FEMALE; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NONHUMAN; OBESITY; OSSIFICATION; OSTEOPENIA; PHENOTYPE; PREVENTION AND CONTROL; TISSUE REGENERATION; UPREGULATION;

ADIPOCYTES; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; DIET; GENE EXPRESSION REGULATION; MALE; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; OBESITY; OSTEOGENESIS; STRESS, MECHANICAL;

EID: 58149084456     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.080817     Document Type: Article

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