Enhanced Gene Transduction into Skeletal Muscle of Mice In Vivo with Pluronic Block Copolymers and Ultrasound Exposure

Cell Biochemistry and Biophysics

Volumn 60, Issue 3, 2011, Pages 267-273

  Chen, Yun Chao ^a   Jiang, Li Ping ^a   Liu, Na Xiang ^a   Ding, Lu ^a   Liu, Xiao Ling ^a   Wang, Zhi Hui ^a   Hong, Kai ^a   Zhang, Qing Ping ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Gene delivery; Pluronic block copolymer; Skeletal muscle; Ultrasound

Indexed keywords

GREEN FLUORESCENT PROTEIN; POLOXAMER; POLYETHYLENE DERIVATIVE; POLYPROPYLENE; UCON 50 HB 5100; UCON 50-HB-5100;

ANIMAL; ARTICLE; C57BL MOUSE; FLUORESCENCE MICROSCOPY; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; METHODOLOGY; MOUSE; PATHOLOGY; SKELETAL MUSCLE; ULTRASOUND;

ANIMALS; GREEN FLUORESCENT PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MUSCLE, SKELETAL; POLOXAMER; POLYETHYLENES; POLYPROPYLENES; TRANSDUCTION, GENETIC; TRANSFECTION; ULTRASONICS;

MUS;

EID: 79958256681     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-010-9149-1     Document Type: Article

References (28)

1. Gregorevic, P., Blankinship, M. J., Allen, J. M., Crawford, R. W., Meuse, L., Miller, D. G., et al. (2004). Systemic delivery of genes to striated muscles using adeno-associated viral vectors. Nature Medicine, 10(8), 828-834.
2. Newman, C. M., & Bettinger, T. (2007). Gene therapy progress and prospects: Ultrasound for gene transfer. Gene Therapy, 14(6), 465-475.
3. Suzuki, R., Takizawa, T., Negishi, Y., Utoguchi, N., & Maruyama, K. (2008). Effective gene delivery with novel liposomal bubbles and ultrasonic destruction technology. International Journal of Pharmaceutics, 354(1-2), 49-55.
4. Lu, Q. L., Liang, H. D., Partridge, T., & Blomley, M. J. K. (2003). Microbubble ultrasound improves the efficiency of gene transduction in skeletal muscle in vivo with reduced tissue damage. Gene Therapy, 10(5), 396-405.
5. Kabanov, A. V., Batrakova, E. V., & Alakhov, V. Y. (2002). Pluronic (R) block copolymers as novel polymer therapeutics for drug and gene delivery. Journal of Controlled Release, 82(2-3), 189-212.
6. Batrakova, E. V., Li, S., Alakhov, V. Y., Miller, D. W., & Kabanov, A. V. (2003). Optimal structure requirements for pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells. Journal of Pharmacology and Experimental Therapeutics, 304(2), 845-854.
7. Kabanov, A. V., Batrakova, E. V., Sriadibhatla, S., Yang, Z., Kelly, D. L., & Alakov, V. Y. (2005). Polymer genomics: Shifting the gene and drug delivery paradigms. Journal of Controlled Release, 101(1-3), 259-271.
8. Chen, Y. C., Liang, H. D., Zhang, Q. P., Blomley, M. J., & Lu, Q. L. (2006). Pluronic block copolymers: Novel functions in ultrasound-mediated gene transfer and against cell damage. Ultrasound in Medicine and Biology, 32(1), 131-137.
9. Lemieux, P., Guerin, N., Paradis, G., Proulx, R., Chistyakova, L., Kabanov, A., et al. (2000). A combination of poloxamers increases gene expression of plasmid DNA in skeletal muscle. Gene Therapy, 7(11), 986-991.
10. Pitard, B., Pollard, H., Agbulut, O., Lambert, O., Vilquin, J. T., Cherel, Y., et al. (2002). A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles. Human Gene Therapy, 13(14), 1767-1775.
11. Hartikka, J., Sukhu, L., Buchner, C., Hazard, D., Bozoukova, V., Margalith, M., et al. (2001). Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: Plasmid dependence of muscle damage and effect of poloxamer 188. Molecular Therapy, 4(5), 407-415.
12. Yang, Z., Zhu, J., Sriadibhatla, S., Gebhart, C., Alakhov, V., & Kabanov, A. (2005). Promoter- and strain-selective enhancement of gene expression in a mouse skeletal muscle by a polymer excipient Pluronic P85. Journal of Controlled Release, 108(2-3), 496-512.
13. Sriadibhatla, S., Yang, Z., Gebhart, C., Alakhov, V. Y., & Kabanov, A. (2006). Transcriptional activation of gene expression by pluronic block copolymers in stably and transiently transfected cells. Molecular Therapy, 13(4), 804-813.
14. Wang, F., Li, K., Chen, Y., Deng, Y., & Hong, K. (2007). Gene transfection mediated by ultrasound and pluronic P85 in HepG2 cells. Journal of Huazhong University of Science and Technology [Medical Sciences], 27(6), 700-702.
15. Miller, D. L., Pislaru, S. V., & Greenleaf, J. E. (2002). Sonoporation: Mechanical DNA delivery by ultrasonic cavitation. Somatic Cell and Molecular Genetics, 27(1-6), 115-134.
16. Liu, J., Lewis, T. N., & Prausnitz, M. R. (1998). Non-invasive assessment and control of ultrasound-mediated membrane permeabilization. Pharmaceutical Research, 15(6), 918-924.
17. Taniyama, Y., Tachibana, K., Hiraoka, K., Aoki, M., Yamamoto, S., Matsumoto, K., et al. (2002). Development of safe and efficient novel nonviral gene transfer using ultrasound: Enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Therapy, 9(6), 372-380.
18. Wang, X., Liang, H. D., Dong, B., Lu, Q. L., & Blomley, M. J. (2005). Gene transfer with microbubble ultrasound and plasmid DNA into skeletal muscle of mice: Comparison between commercially available microbubble contrast agents. Radiology, 237(1), 224-229.
19. Koch, S., Pohl, P., Cobet, U., & Rainov, N. G. (2000). Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects. Ultrasound in Medicine and Biology, 26(5), 897-903.
20. Zhang, Q. X., Wang, Z. G., Ran, H. T., Fu, X. P., Li, X. D., & Zheng, Y. Y. (2006). Enhanced gene delivery into skeletal muscles with ultrasound and microbubble techniques. Academic Radiology, 13(3), 363-367.
21. Larina, I. V., Evers, B. M., & Esenaliev, R. O. (2005). Optimal drug and gene delivery in cancer cells by ultrasound-induced cavitation. Anticancer Research, 25(1A), 149-156.
22. Gilmore, T. D. (1999). The Rel/NF-kappaB signal transduction pathway: Introduction. Oncogene, 18(49), 6842-6844.
23. Batrakova, E. V., & Kabanov, A. V. (2008). Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers. Journal of Controlled Release, 130(2), 98-106.
24. Meijering, B. D., Juffermans, L. J., van Wamel, A., Henning, R. H., Zuhorn, I. S., Emmer, M., et al. (2009). Ultrasound and microbubble-targeted delivery of macromolecules is regulated by induction of endocytosis and pore formation. Circulation Research, 104(5), 679-687.
25. Sahay, G., Batrakova, E. V., & Kabanov, A. V. (2008). Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport. Bioconjugate Chemistry, 19(10), 2023-2029.
26. Roques, C., Bouchemal, K., Ponchel, G., Fromes, Y., & Fattal, E. (2009). Parameters affecting organization and transfection efficiency of amphiphilic copolymers/DNA carriers. Journal of Controlled Release, 138(1), 71-77.
27. Kabanov, A. V., Batrakova, E. V., & Alakhov, V. Y. (2003). An essential relationship between ATP depletion and chemosensitizing activity of Pluronic((R)) block copolymers. Journal of Controlled Release, 91(1-2), 75-83.
28. Kabanov, A. V., Lemieux, P., Vinogradov, S., & Alakhov, V. (2002). Pluronic((R)) block copolymers: Novel functional molecules for gene therapy. Advanced Drug Delivery Reviews, 54(2), 223-233.