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Volumn 152, Issue 3, 2011, Pages 411-417

The effect of dextrin-rhEGF on the healing of full-thickness, excisional wounds in the (db/db) diabetic mouse

Author keywords

(db db) diabetic mouse; Dextrin rhEGF conjugate; Nanomedicine; Polymer therapeutics; PUMPT; Wound repair

Indexed keywords

DEXTRIN-RHEGF CONJUGATE; DIABETIC MICE; NANOMEDICINES; POLYMER THERAPEUTICS; PUMPT; WOUND REPAIR;

EID: 79958238832     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.03.016     Document Type: Article
Times cited : (76)

References (42)
  • 3
    • 1642567557 scopus 로고    scopus 로고
    • Growth factors and chronic wound healing: Past, present and future
    • R. Goldman Growth factors and chronic wound healing: past, present and future Adv. Skin Wound Care 17 2004 24 35
    • (2004) Adv. Skin Wound Care , vol.17 , pp. 24-35
    • Goldman, R.1
  • 4
    • 33744780764 scopus 로고    scopus 로고
    • The molecular biology of chronic wounds and delayed healing in diabetes
    • DOI 10.1111/j.1464-5491.2006.01773.x
    • R. Blakytny, and E. Jude The molecular biology of chronic wounds and delayed healing in diabetes Diabet. Med. 23 2006 594 608 (Pubitemid 43830059)
    • (2006) Diabetic Medicine , vol.23 , Issue.6 , pp. 594-608
    • Blakytny, R.1    Jude, E.2
  • 5
    • 33846627240 scopus 로고    scopus 로고
    • Pathophysiology of acute wound healing
    • DOI 10.1016/j.clindermatol.2006.09.007, PII S0738081X06001386
    • J. Li, J. Chen, and R. Kirsner Pathophysiology of acute wound healing Clin. Dermatol. 25 2007 9 18 (Pubitemid 46177460)
    • (2007) Clinics in Dermatology , vol.25 , Issue.1 , pp. 9-18
    • Li, J.1    Chen, J.2    Kirsner, R.3
  • 6
    • 0347725622 scopus 로고    scopus 로고
    • Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors
    • D.R. Yager, S.M. Chen, S.I. Ward, O.O. Olutoye, R.F. Diegelmann, and I.K. Cohen Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors Wound Rep. Regen. 5 1997 23 32 (Pubitemid 127686717)
    • (1997) Wound Repair and Regeneration , vol.5 , Issue.1 , pp. 23-32
    • Yager, D.R.1    Chen, S.M.2    Ward, S.I.3    Olutoye, O.O.4    Diegelmann, R.F.5    Cohen, I.K.6
  • 7
    • 28944443107 scopus 로고    scopus 로고
    • Oxidative stress in chronic venous leg ulcers
    • DOI 10.1111/j.1067-1927.2005.00065.x
    • M. Wlaschek, and K. Scharffetter-Kochanek Oxidative stress in chronic venous leg ulcers Wound Rep. Regen. 13 2005 452 461 (Pubitemid 41783163)
    • (2005) Wound Repair and Regeneration , vol.13 , Issue.5 , pp. 452-461
    • Wlaschek, M.1    Scharffetter-Kochanek, K.2
  • 9
    • 0032720053 scopus 로고    scopus 로고
    • Efficacy and safety of becaplermin (recombinant human platelet-derived growth factor-BB)in patients with nonhealing, lower extremity diabetic ulcers: A combined analysis of four randomized studies
    • DOI 10.1046/j.1524-475X.1999.00335.x
    • J.M. Smiell, T.J. Wieman, D.L. Steed, B.H. Perry, A.R. Sampson, and B.H. Schwab Efficacy and safety of becaplermin (recombinant human platelet-derived growth factor-BB) in patients with non-healing, lower extremity diabetic ulcers: a combined analysis of four randomized studies Wound Rep. Regen. 7 1999 335 346 (Pubitemid 29523009)
    • (1999) Wound Repair and Regeneration , vol.7 , Issue.5 , pp. 335-346
    • Smiell, J.M.1    Wieman, T.J.2    Steed, D.L.3    Perry, B.H.4    Sampson, A.R.5    Schwab, B.H.6
  • 10
    • 84866604477 scopus 로고    scopus 로고
    • Update of Safety Review: Follow-up to the March 27, 2008, Communication about the Ongoing Safety Review of Regranex (Becaplermin). June 6, 2008 http://www.fda.gov/Drugs/DrugSafety/ PostmarketDrugSafetyInformationforPatientsandProviders/ DrugSafetyInformationforHeathcareProfessionals/ucm072121.htm
  • 13
    • 0028334260 scopus 로고
    • PDGF and TGF-α act synergistically to improve wound healing in the genetically diabetic mouse
    • DOI 10.1006/jsre.1994.1090
    • R.L. Brown, M.P. Breeden, and D.G. Greenhalgh PDGF and TGF-α act synergistically to improve wound healing in the genetically diabetic mouse J. Surg. Res. 56 1994 562 570 (Pubitemid 24222406)
    • (1994) Journal of Surgical Research , vol.56 , Issue.6 , pp. 562-570
    • Brown, R.L.1    Breeden, M.P.2    Greenhalgh, D.G.3
  • 14
    • 2442717879 scopus 로고    scopus 로고
    • Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells
    • R.D. Galiano, O.M. Tepper, C.R. Pelo, K.A. Bhatt, M. Callaghan, N. Bastidas, S. Bunting, H.G. Steinmetz, and G.C. Gurtner Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis by mobilizing and recruiting bone-marrow-derived cells Am. J. Pathol. 164 2004 1935 1947 (Pubitemid 38669343)
    • (2004) American Journal of Pathology , vol.164 , Issue.6 , pp. 1935-1947
    • Galiano, R.D.1    Tepper, O.M.2    Pelo, C.R.3    Bhatt, K.A.4    Callaghan, M.5    Bastidas, N.6    Bunting, S.7    Steinmetz, H.G.8    Gurtner, G.C.9
  • 15
    • 33748744521 scopus 로고    scopus 로고
    • Advances in the management of leg ulcers - The potential role of growth factors
    • DOI 10.1111/j.1742-4801.2006.00211.x
    • M.N. Khan, and C.G. Davies Advances in the management of leg ulcers - the potential role of growth factors Int. Wound J. 3 2006 113 120 (Pubitemid 44400782)
    • (2006) International Wound Journal , vol.3 , Issue.2 , pp. 113-120
    • Khan, M.N.1    Davies, C.G.2
  • 16
    • 43149109689 scopus 로고    scopus 로고
    • Polymer masked-unmasked protein therapy. 1. Bioresponsive dextrin-trypsin and -melanocyte stimulating hormone conjugates designed for α-amylase activation
    • DOI 10.1021/bm701073n
    • R. Duncan R, H.R.P. Gilbert, R.J. Carbajo, and M.J. Vicent Polymer masked-unmasked protein therapy (PUMPT) 1. Bioresponsive dextrin-trypsin and -MSH conjugates designed for α-amylase activation Biomacromolecules 9 2008 1146 1154 (Pubitemid 351639566)
    • (2008) Biomacromolecules , vol.9 , Issue.4 , pp. 1146-1154
    • Duncan, R.1    Gilbert, H.R.P.2    Carbajo, R.J.3    Vicent, M.J.4
  • 18
    • 77953248216 scopus 로고    scopus 로고
    • Promotion of acute and chronic wound healing by bioresponsive dextrin-rhEGF polymer conjugates
    • J. Hardwicke, R. Moseley, P. Stephens, K. Harding, R. Duncan, and D.W. Thomas Promotion of acute and chronic wound healing by bioresponsive dextrin-rhEGF polymer conjugates Mol. Pharm. 7 2010 699 707
    • (2010) Mol. Pharm. , vol.7 , pp. 699-707
    • Hardwicke, J.1    Moseley, R.2    Stephens, P.3    Harding, K.4    Duncan, R.5    Thomas, D.W.6
  • 19
    • 78649880473 scopus 로고    scopus 로고
    • Investigation of the potential of polymer therapeutics in corneal re-epithelialisation
    • J. Hardwicke, B. Song, R. Moseley, and D.W. Thomas Investigation of the potential of polymer therapeutics in corneal re-epithelialisation Br. J. Opthalmol. 94 2010 1566 1570
    • (2010) Br. J. Opthalmol. , vol.94 , pp. 1566-1570
    • Hardwicke, J.1    Song, B.2    Moseley, R.3    Thomas, D.W.4
  • 21
    • 34548008143 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate accelerates wound healing in diabetic mice
    • DOI 10.1016/j.jdermsci.2007.06.002, PII S0923181107002174
    • T. Kawanabe, T. Kawakami, Y. Yatomi, S. Shimida, and Y. Soma Sphingosine 1-phosphate accelerates wound healing in diabetic mice J. Dermatol. Sci. 48 2007 53 60 (Pubitemid 47284808)
    • (2007) Journal of Dermatological Science , vol.48 , Issue.1 , pp. 53-60
    • Kawanabe, T.1    Kawakami, T.2    Yatomi, Y.3    Shimada, S.4    Soma, Y.5
  • 23
    • 76549091233 scopus 로고    scopus 로고
    • Hyaluronan oligosaccharides promote excisional wound healing through enhanced angiogenesis
    • F. Gao, Y. Liu, Y. He, C. Yang, Y. Wang, X. Shi, and G. Wei Hyaluronan oligosaccharides promote excisional wound healing through enhanced angiogenesis Matrix Biol. 29 2010 107 116
    • (2010) Matrix Biol. , vol.29 , pp. 107-116
    • Gao, F.1    Liu, Y.2    He, Y.3    Yang, C.4    Wang, Y.5    Shi, X.6    Wei, G.7
  • 24
    • 0035818460 scopus 로고    scopus 로고
    • Dextrins as potential carriers for drug targeting: Tailored rates of dextrin degradation by introduction of pendant groups
    • DOI 10.1016/S0378-5173(01)00859-6, PII S0378517301008596
    • D. Hreczuk-Hirst, D. Chicco, L. German, and R. Duncan Dextrins as potential carriers for drug targeting: tailored rates of dextrin degradation by introduction of pendant groups Int. J. Pharm. 230 2001 57 66 (Pubitemid 32973859)
    • (2001) International Journal of Pharmaceutics , vol.230 , Issue.1-2 , pp. 57-66
    • Hreczuk-Hirst, D.1    Chicco, D.2    German, L.3    Duncan, R.4
  • 25
    • 0025873304 scopus 로고
    • Molecular and cellular properties of PECAM-1 (endoCAM/CD31): A novel vascular cell-cell adhesion molecule
    • S.M. Albelda, W.A. Muller, C.A. Buck, and P.J. Newman Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule J. Cell Biol. 114 1991 1059 1068 (Pubitemid 21909867)
    • (1991) Journal of Cell Biology , vol.114 , Issue.5 , pp. 1059-1068
    • Albelda, S.M.1    Muller, W.A.2    Buck, C.A.3    Newman, P.J.4
  • 26
    • 35748972337 scopus 로고    scopus 로고
    • Recombinant human epidermal growth factor (REGEN-D™ 150): Effect on healing of diabetic foot ulcers
    • DOI 10.1016/j.diabres.2007.06.004, PII S0168822707003129
    • V.K. Mohan Recombinant human epidermal growth factor (REGEN-D 150): effect on healing of diabetic foot ulcers Diab. Res. Clin. Pract. 78 2007 405 411 (Pubitemid 350047511)
    • (2007) Diabetes Research and Clinical Practice , vol.78 , Issue.3 , pp. 405-411
    • Mohan, V.K.1
  • 28
    • 0032197374 scopus 로고    scopus 로고
    • Evaluation of linear polyethyleneimine/nitric oxide adduct on wound repair: Therapy versus toxicity
    • J.A. Bauer, W. Rao, and D.J. Smith Evaluation of linear polyethyleneimine/nitric oxide adduct on wound repair: therapy versus toxicity Wound Rep. Regen. 6 1998 569 577 (Pubitemid 128659204)
    • (1998) Wound Repair and Regeneration , vol.6 , Issue.6 , pp. 569-577
    • Bauer, J.A.1    Rao, W.2    Smith, D.J.3
  • 29
    • 79958185589 scopus 로고    scopus 로고
    • Effective acceleration of wound healing by simultaneous transfection of hepatocyte growth factor gene and prostacyclin synthase gene using Shima Jet
    • Y. Kunugiza, N. Tomita, T. Tomita, H. Hashimoto, K. Yamasaki, H. Koike, H. Yoshikawa, and R. Morishita Effective acceleration of wound healing by simultaneous transfection of hepatocyte growth factor gene and prostacyclin synthase gene using Shima Jet Mol. Ther. 9 2004 S397
    • (2004) Mol. Ther. , vol.9 , pp. 397
    • Kunugiza, Y.1    Tomita, N.2    Tomita, T.3    Hashimoto, H.4    Yamasaki, K.5    Koike, H.6    Yoshikawa, H.7    Morishita, R.8
  • 30
    • 68049133319 scopus 로고    scopus 로고
    • Avotermin for the improvement of scar appearance: A new pharmaceutical in a new therapeutic area
    • N.L. Occleston, D. Fairlamb, J. Hutchison, S. O'Kane, and M.W.J. Ferguson Avotermin for the improvement of scar appearance: a new pharmaceutical in a new therapeutic area Exp. Op. Invest. Drugs 18 2009 1231 1239
    • (2009) Exp. Op. Invest. Drugs , vol.18 , pp. 1231-1239
    • Occleston, N.L.1    Fairlamb, D.2    Hutchison, J.3    O'Kane, S.4    Ferguson, M.W.J.5
  • 32
    • 0036288833 scopus 로고    scopus 로고
    • Preparation and characterization of mono-PEGylated epidermal growth factor: Evaluation of in vitro biologic activity
    • DOI 10.1023/A:1016113117851
    • H. Lee, and T.G. Park Preparation and characterization of mono-PEGylated epidermal growth factor: evaluation of in vitro biologic activity Pharm. Res. 19 2002 845 851 (Pubitemid 34686745)
    • (2002) Pharmaceutical Research , vol.19 , Issue.6 , pp. 845-851
    • Lee, H.1    Park, T.G.2
  • 33
    • 33845201165 scopus 로고    scopus 로고
    • Effect of molecular size of PEGylated recombinant human epidermal growth factor on the biological activity and stability in rat wound tissue
    • DOI 10.1080/10837450600941053, PII J7N12521UU0M727X
    • D.H. Na, Y.S. Youn, I.B. Lee, E.J. Park, C.J. Park, and K.C. Lee Effect of molecular size of pegylated recombinant human epidermal growth factor on the biological activity and stability in rat wound tissue Pharm. Dev. Technol. 11 2006 513 519 (Pubitemid 44852433)
    • (2006) Pharmaceutical Development and Technology , vol.11 , Issue.4 , pp. 513-519
    • Na, D.H.1    Youn, Y.S.2    Lee, I.B.3    Park, E.J.4    Park, C.J.5    Lee, K.C.6
  • 34
    • 39049132284 scopus 로고    scopus 로고
    • Self-assembling peptide nanofiber scaffolds accelerate wound healing
    • A. Schneider, J.A. Garlick, and C. Egles Self-assembling peptide nanofiber scaffolds accelerate wound healing PLoS ONE 3 2008 e1410
    • (2008) PLoS ONE , vol.3 , pp. 1410
    • Schneider, A.1    Garlick, J.A.2    Egles, C.3
  • 35
    • 36048959183 scopus 로고    scopus 로고
    • In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF)
    • DOI 10.1016/j.biomaterials.2007.10.012, PII S0142961207008022
    • J.S. Choi, K.W. Leong, and H.S. Yoo in vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF) Biomaterials 29 2008 587 596 (Pubitemid 350100803)
    • (2008) Biomaterials , vol.29 , Issue.5 , pp. 587-596
    • Choi, J.S.1    Leong, K.W.2    Yoo, H.S.3
  • 36
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • DOI 10.1038/nrd1088
    • R. Duncan The dawning era of polymer therapeutics Nat. Rev. Drug Disc. 2 2003 347 360 (Pubitemid 37361705)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.5 , pp. 347-360
    • Duncan, R.1
  • 38
    • 26444587113 scopus 로고    scopus 로고
    • Acceleration of wound healing by gelatin film dressings with epidermal growth factor
    • DOI 10.1292/jvms.67.909
    • A. Tanaka, T. Nagate, and H. Matsuda Acceleration of wound healing by gelatin film dressings with epidermal growth factor J. Vet. Med. Sci. 67 2005 909 913 (Pubitemid 41436280)
    • (2005) Journal of Veterinary Medical Science , vol.67 , Issue.9 , pp. 909-913
    • Tanaka, A.1    Nagate, T.2    Matsuda, H.3
  • 39
    • 33645070777 scopus 로고    scopus 로고
    • An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor
    • C. Alemdaroĝlu, Z. Deǧim, N. Celebi, F. Zor, S. Oztürk, and D. Erdoĝan An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor Burns 32 2006 319 327
    • (2006) Burns , vol.32 , pp. 319-327
    • Alemdaroĝlu, C.1    Deǧim, Z.2    Celebi, N.3    Zor, F.4    Oztürk, S.5    Erdoĝan, D.6
  • 40
    • 0024807218 scopus 로고
    • Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo
    • DOI 10.1083/jcb.109.6.2741
    • W.H. Lai, P.H. Cameron, I. Wada, J. Doherty, D.G. Kay, B.I. Posner, and J.J.M. Bergeron Ligand-mediated internalization, recycling and downregulation of the epidermal growth factor receptor in vivo J. Cell Biol. 109 1989 2741 2749 (Pubitemid 20011901)
    • (1989) Journal of Cell Biology , vol.109 , Issue.6 , pp. 2741-2749
    • Lai, W.H.1    Cameron, P.H.2    Wada, I.3    Doherty II, J.-J.4    Kay, D.G.5    Posner, B.I.6    Bergeron, J.J.M.7
  • 41
    • 52449133379 scopus 로고    scopus 로고
    • Wound healing dressings and drug delivery systems: A review
    • H.N.E. Stevens, and G.M. Eccleston Wound healing dressings and drug delivery systems: a review J. Pharm. Sci. 97 2008 2892 2923
    • (2008) J. Pharm. Sci. , vol.97 , pp. 2892-2923
    • Stevens, H.N.E.1    Eccleston, G.M.2
  • 42
    • 0031657229 scopus 로고    scopus 로고
    • Preclinical promise of becaplermin (rhPDGF-BB) in wound healing
    • DOI 10.1016/S0002-9610(98)00177-9, PII S0002961098001779
    • E.K. Le Grand Preclinical promise of becaplermin (rhPDGF-BB) in wound healing Am. J. Surg. 176 1998 48S 54S (Pubitemid 28460657)
    • (1998) American Journal of Surgery , vol.176 , Issue.2
    • LeGrand, E.K.1


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