Neuropsychological attention skills and related behaviours in adults with tuberous sclerosis complex

Behavior Genetics

Volumn 41, Issue 3, 2011, Pages 437-444

  Tierney, Kevin M ^a   McCartney, Deborah L ^b,c   Serfontein, Jaco R ^a   De Vries, Petrus J ^a,b  

^a CAMBRIDGESHIRE AND PETERBOROUGH NHS FOUNDATION TRUST   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Attention Deficit Scales for Adults; Dual tasking; Mammalian target of rapamycin; mTOR; Neurodevelopmental disorders; TEA Ch

Indexed keywords

ADULT; ARTICLE; ATTENTION; ATTENTION DEFICIT DISORDER; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DAILY LIFE ACTIVITY; EMOTIONALITY; FEMALE; HUMAN; MALE; MENTAL TASK; SELECTIVE ATTENTION; SUSTAINED ATTENTION; TASK PERFORMANCE; TUBEROUS SCLEROSIS;

ADULT; ATTENTION; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; EPILEPSY; FEMALE; HUMANS; INTELLIGENCE; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PHENOTYPE; PSYCHOMETRICS; TOR SERINE-THREONINE KINASES; TUBEROUS SCLEROSIS;

MAMMALIA;

EID: 79958238519     PISSN: 00018244     EISSN: 15733297     Source Type: Journal    
DOI: 10.1007/s10519-010-9423-4     Document Type: Article

References (34)

1. Cohen J (1988) Statistical power analysis for the behavioural sciences, 2nd edn. Lawrence Erlbaum Associates, Hillsdale
2. PB Crino KL Nathanson EP Henske 2006 The tuberous sclerosis complex N Engl J Med 355 1345 1356 17005952 10.1056/NEJMra055323 (Pubitemid 44465463)
3. P Curatolo R Bombardieri S Jozwiak 2008 Tuberous sclerosis Lancet 372 657 668 18722871 10.1016/S0140-6736(08)61279-9
4. de Vries PJ (2010) Neurodevelopmental, psychiatric and cognitive aspects of tuberous sclerosis complex. In: Kwiatkowski DJ, Whittemore VH, Thiele EA (eds) Tuberous sclerosis complex: genes, clinical features, and therapeutics. Wiley-VCH, Weinheim, pp 229-266
5. PJ de Vries CJ Howe 2007 The tuberous sclerosis complex proteins: a GRIPP on cognition and neurodevelopment Trends Mol Med 13 319 326 17632034 10.1016/j.molmed.2007.06.003 (Pubitemid 47126986)
6. PJ de Vries A Hunt PF Bolton 2007 The psychopathologies of children and adolescents with tuberous sclerosis complex (TSC): a postal survey of UK families Eur Child Adolesc Psychiatry 16 16 24 17268883 10.1007/s00787-006-0570- 3 (Pubitemid 46648361)
7. PJ de Vries PA Prather 2007 The tuberous sclerosis complex N Engl J Med 356 92 94 17202464 10.1056/NEJMc062928
8. PJ de Vries P Watson 2008 Attention deficits in tuberous sclerosis complex (TSC): rethinking the pathways to end state J Intellect Disabil Res 52 848 857
9. PJ de Vries A Humphrey D McCartney P Prather P Bolton A Hunt 2005 Consensus clinical guidelines for the assessment of cognitive and behavioural problems in tuberous sclerosis Eur Child Adolesc Psychiatry 14 183 190 15981129 10.1007/s00787-005-0443-1
10. PJ de Vries J Gardiner PF Bolton 2009 Neuropsychological attention deficits in tuberous sclerosis complex (TSC) Am J Med Genet 149A 387 395 19215038 10.1002/ajmg.a.32690
11. Ehninger D, Silva AJ (2011) Increased levels of anxiety-related behaviors in a Tsc2 dominant negative transgenic mouse model of tuberous sclerosis. Behav Genet. doi: 10.1007/s10519-010-9398-1 (online early BEGE)
12. +/-mouse model of tuberous sclerosis Nat Med 14 843 848 18568033 10.1038/nm1788
13. JC Gillberg C Gillberg G Ahlsén 1993 Autistic behaviour and attention deficits in tuberous sclerosis: a population based study Dev Med Child Neurol 36 50 56 10.1111/j.1469-8749.1994.tb11765.x
14. SM Goorden GM van Woerden L van der Weerd JP Cheadle Y Elgersma 2007 Cognitive deficits in Tsc1 ± mice in the absence of cerebral lesions and seizures Ann Neurol 62 648 655 18067135 10.1002/ana.21317
15. JE Harrison FJ O'Callaghan E Hancock JP Osborne PF Bolton 1999 Cognitive deficits in normally intelligent patients with tuberous sclerosis Am J Med Genet 88 642 646 10581483 10.1002/(SICI)1096-8628(19991215)88:6<642::AID- AJMG12>3.0.CO;2-O
16. FE Jansen O Braams KL Vincken A Algra P Anbeek A Jennejens-Schinkel D Halley BA Zonnenberg A van den Ouweland AC van Huffelen O van Nieuwenhuizen M Nellist 2008 Overlapping neurologic and cognitive phenotypes in patients with TSC1 or TSC2 mutations Neurology 70 908 915 18032745 10.1212/01.wnl.0000280578. 99900.96 (Pubitemid 351430757)
17. C Joinson FJ O'Callaghan JP Osborne C Martyn T Harris PF Bolton 2003 Learning disability and epilepsy in an epidemiological sample of individuals with tuberous sclerosis complex Psychol Med 33 335 344 12622312 10.1017/S0033291702007092 (Pubitemid 36221465)
18. Kwiatkowski DJ (2010) Genetics of tuberous sclerosis complex. In: Kwiatkowski DJ, Whittemore VH, Thiele EA (eds) Tuberous sclerosis complex: genes, clinical features, and therapeutics. Wiley-VCH, Weinheim, pp 29-60
19. Manly T, Robertson IH, Anderson V, Nimmo-Smith I (1999) Test of Everyday Attention for Children (TEA-Ch) manual. Thames Valley Test Company, Suffolk
20. T Manly V Anderson I Nimmo-Smith A Turner P Watson IH Robertson 2001 The differential assessment of children's attention: the test of everyday attention for children (TEA-Ch), normative sample and ADHD performance J Child Psychol Psychiatry 42 1065 1081 11806689 10.1111/1469-7610.00806 (Pubitemid 34044274)
21. BS McCann P Roy-Byrne 2004 Screening and diagnostic utility of self-report attention deficit hyperactivity disorder scales in adults Compr Psychiatry 45 175 183 15124147 10.1016/j.comppsych.2004.02.006 (Pubitemid 38656673)
22. JP Osborne A Fryer D Webb 1991 Epidemiology of tuberous sclerosis Ann N Y Acad Sci 615 125 127 2039137 10.1111/j.1749-6632.1991.tb37754.x
23. S Povey MW Burley J Attwood F Benham D Hunt SJ Jeremiah D Franklin G Gillett S Malas EB Robson P Tippett JH Edqards DJ Kwiatkowski M Super R Mueller A Fryer A Clarke D Webb J Osborne 1994 Two loci for tuberous sclerosis: one on 9q34 and one on 16p13 Ann Hum Genet 58 107 127 7979156 10.1111/j.1469-1809.1994. tb01881.x
24. PA Prather PJ de Vries 2004 Behavioral and cognitive aspects of tuberous sclerosis complex J Child Neurol 19 666 674 15563012
25. PA Prather EA Thiele PJ de Vries 2006 Neuropsychological profiling in tuberous sclerosis complex (TSC): implications for neurobiological and clinical interventions J Intellect Disabil Res 50 788
26. K Ridler J Suckling NJ Higgins PJ de Vries CME Stephenson PF Bolton 2007 Neuroanatomical correlates of memory deficits in tuberous sclerosis complex Cereb Cortex 17 261 271 16603714 10.1093/cercor/bhj144 (Pubitemid 46052765)
27. ES Roach M Gomez H Northrup 1998 Tuberous sclerosis complex consensus conference: revised clinical diagnostic criteria J Child Neurol 13 624 628 9881533 10.1177/088307389801301206 (Pubitemid 29035481)
28. Robertson IH, Ward T, Ridgeway V, Nimmo-Smith I (1994) The test of everyday attention: manual. Thames Valley Test Company, Suffolk
29. Serfontein J, Nisbet RER, Howe CJ, de Vries PJ (in press) Conservation of structural and functional elements of TSC1 and TSC2: a bioinformatic comparison across animal models. Behav Genet. doi: 10.1007/s10519-010-9440-3
30. J Serfontein RER Nisbet CJ Howe PJ de Vries 2010 Evolution of the TSC1/TSC2-TOR signaling pathway Sci Signal 3 128 ra49 20587805 10.1126/scisignal.2000803
31. Triolo SJ, Murphy KR (1996) Attention-Deficit Scales for Adults (ADSA): manual for scoring and interpretation. Brunner/Mazel Publishers, New York
32. Waltereit R, Japs B, Schneider M, de Vries PJ, Bartsch D (2011) Epilepsy and Tsc2 haploinsufficiency lead to autistic-like social deficit behaviors in rats. Behav Genet. doi: 10.1007/s10519-101-9399-0 (online early BEGE)
33. R Waltereit H Welzi J Dichigans HP Lipp WJ Schmidt M Weller 2006 Enhanced episodic-like memory and kindling epilepsy in a rat model of tuberous sclerosis J Neurochem 96 407 413 16300636 10.1111/j.1471-4159.2005.03538.x
34. Wechsler D (1999) Wechsler Abbreviated Scale of Intelligence (WASI). Harcourt Assessment, San Antonio