The psychopathologies of children and adolescents with tuberous sclerosis complex (TSC): A postal survey of UK families

European Child and Adolescent Psychiatry

Volumn 16, Issue 1, 2007, Pages 16-24

  De Vries, Petrus J ^a   Hunt, Ann ^b   Bolton, Patrick F ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Tuberous Sclerosis Association   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Autism spectrum disorders; Behavioural phenotype; Cognition; Disruptive behaviour disorders; Variability of expression

Indexed keywords

ADOLESCENT; AGGRESSION; ANXIETY; ATTENTION DEFICIT DISORDER; AUTISM; BEHAVIOR DISORDER; CHILD; CONTROLLED STUDY; DEPRESSION; DEVELOPMENTAL DISORDER; EPILEPSY; FAMILY STUDY; FEMALE; HEALTH SURVEY; HEMANGIOFIBROMA; HUMAN; LANGUAGE DISABILITY; MALE; MENTAL DEFICIENCY; MENTAL DISEASE; PHYSICAL DISEASE; REVIEW; SEX DIFFERENCE; SPEECH DISORDER; TUBEROUS SCLEROSIS; UNITED KINGDOM;

ADOLESCENT; CHILD; COMORBIDITY; DEPRESSION; FEMALE; GREAT BRITAIN; HEALTH SURVEYS; HUMANS; MALE; MENTAL RETARDATION; PARENTS; QUESTIONNAIRES; REPRODUCIBILITY OF RESULTS; SEX CHARACTERISTICS; TUBEROUS SCLEROSIS;

EID: 34247529566     PISSN: 10188827     EISSN: 1435165X     Source Type: Journal    
DOI: 10.1007/s00787-006-0570-3     Document Type: Review

References (34)

1. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders (DSM-IV), 4th ed. American Psychiatric Association, Washington, DC
2. Bolton PF (2004) Neuro-epileptic correlates of autistic symptomatology in tuberous sclerosis. Ment Retard Dev Disabil Res Rev 10:126-131
3. Bolton PF, Park RJ, Higgins JN, Griffiths PD, Pickles A (2002) Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex. Brain 125:1247-1255
4. Bolton PF, Griffiths PD (1997) Association of tuberous sclerosis of temporal lobes with autism and atypical autism. Lancet 349(9049):392-395
5. Clarke A, Cook P, Osborne JP (1996) Cranial computed tomographic findings in tuberous sclerosis are not affected by sex. Dev Med Child Neurol 38(2):139-145
6. Dabora SL, Jozwiak S, Franz DN, Roberts PS, Nieto A, Chung J, Choy Y, Reeve MP, Thiele E, Egelhoff JC, Kasprzyk-Obara J, Domanska-Pakiela D, Kwiatkowski DJ (2001) Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1 disease in multiple organs. Am J Hum Genet 68:64-80
7. de Vries PJ, Bolton PF (2000) Genotype -phenotype correlations in Tuberous Sclerosis. J Med Genet 37:e3
8. de Vries P, Humphrey A, McCartney D, Prather P, Bolton P, Hunt A, TSC Behaviour Consensus Panel (2005) Consensus clinical guidelines for the assessment of cognitive and behavioural problems in Tuberous Sclerosis. Eur Child Adolesc Psychiatry 14(4):183-190
9. Emerson E (2003) Prevalence of psychiatric disorders in children and adolescents with and without intellectual disability. J Intellect Disabil Res 47(1):51-58
10. Fombonne E (1999) The epidemiology of autism: a review. Psychol Med 29:769-786
11. Gillberg IC, Gillberg C, Ahlsen G (1994) Autistic behaviour and attention deficits in tuberous sclerosis: a population-based study. Dev Med Child Neurol 36:50-56
12. Goodman R (1997) The strengths and difficulties questionnaire: a research note. J Child Adolesc Psychopharmacol 38(5):581-586
13. Hunt A (1998) A comparison of the abilities, health and behaviour of 23 people with Tuberous Sclerosis and age 5 and as adults. J Appl Res Intellect Disabil 11(3):227-238
14. Hunt A (1993) Development, behaviour and seizures in 300 cases of tuberous sclerosis. J Intellect Disabil Res 37(1):41-51
15. Hunt A (1983) Tuberous sclerosis: a survey of 97 cases. III: Family aspects. Dev Med Child Neurol 25(3):353-357
16. Hunt A, Dennis J (1987) Psychiatric disorder among children with tuberous sclerosis. Dev Med Child Neurol 29(2):190-198
17. Hunt A, Shepherd C (1993) A prevalence study of autism in tuberous sclerosis. J Autism Dev Disord 23(2):323-339
18. Joinson C, O'Callaghan FJ, Osborne JP, Martyn C, Harris T, Bolton PF (2003) Learning disability and epilepsy in an epidemiological sample of individuals with tuberous sclerosis complex. Psychol Med 33(2):334-344
19. Jones AC, Daniells CE, Snell RG, Tachataki M, Idziaszczyk SA, Krawczak M, Sampson JR, Cheadle JP (1997) Molecular genetic and phenotypic analysis reveals differences between TSC1 and TSC2 associated familial and sporadic tuberous sclerosis. Hum Mol Genet 6(12):2155-2161
20. Lewis JC, Thomas HV, Murphy KC, Sampson JR (2004) Genotype and psychological phenotype in tuberous sclerosis. J Med Genet 41: 203-207
21. Lord C, Rutter M, Goode S, Heemsbergen J, Jordan H, Mawhood L, Schopler E (1989) Autism diagnostic observation schedule: a standardised observation of communication and social behavior. J Autism Dev Disord 19(2):185-212
22. Lord C, Rutter M, Le Couteur A (1994) Autism diagnostic interview-revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 24:659-685
23. Meltzer H, Gatward R, Goodman R, Ford T (2000) Mental health of children and adolescents in Great Britain. The Stationery Office, London
24. O'Callaghan F (1999) Tuberous sclerosis. Br Med J 318(7190):1019-1020
25. O'Callaghan F, Noakes M, Osborne JP (2000) Renal angiomyolipomata and learning difficulty in tuberous sclerosis complex. J Med Genet 37:156-157
26. Pickles A, Starr E, Kazak S, Bolton P, Papanicolaou K, Bailey A, Goodman R, Rutter M (2000) Variable expression of the autism broader phenotype: findings from extended pedigrees. J Child Psychol Psychiatry 41(4):491-502
27. Povey S, Burley MW, Attwood J, Benham F, Hunt D, Jeremiah SJ, Franklin D, Gillett G, Malas S, Robson EB, Tippett P, Edwards JH, Kwaitkowski DJ, Super M, Mueller R, Fryer A, Clarke A, Webb D, Osborne J (1994) Two loci for tuberous sclerosis: one on 9q34 and one on 16p13. Ann Hum Genet 58(2):107-127
28. Prather P, de Vries PJ (2004) Behavioral and cognitive aspects of tuberous sclerosis complex. J Child Neurol 19(9):666-674
29. Raven J (1956) Coloured progressive matrices. Oxford Psychologists Press, Oxford
30. Roach E, Gomez M, Northrup H (1998) Tuberous Sclerosis consensus conference: revised diagnostic criteria. J Child Neurol 13(12):624-628
31. Smalley SL, Burger F, Smith M (1994) Phenotypic variation of tuberous sclerosis in a single extended kindred. J Med Genet 31(10):761-765
32. Webb DW, Fryer AE, Osborne JP (1996) Morbidity associated with tuberous sclerosis: a population study. Dev Med Child Neurol 38(2):146-155
33. Wechsler D (1992) Wechsler intelligence scale for children - third edition, UK. The Psychological Corporation Limited, London
34. World Health Organisation (1992) The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. World Health Organisation, Geneva, p 362