Association of functionally important polymorphism of microsomal epoxide hydrolase gene (EPHX1) with lung cancer susceptibility

Cancer Investigation

Volumn 29, Issue 6, 2011, Pages 411-418

  Tilak, Anup R ^a   Kumar, Sachin ^b   Jain, Meenu ^c   Pant, Mohan C ^d   Das, Bhudev C ^e   Guleria, Randeep ^b   Mittal, Balraj ^c   Mathur, Neeraj ^a   Kumar, Ashwani ^a,f  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^d UNIVERSITY OF LUCKNOW   (India)

^e INSTITUTE OF CYTOLOGY AND PREVENTIVE ONCOLOGY   (India)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

EPHX1; Lung cancer; Single nucleotide polymorphism (SNP)

Indexed keywords

EPOXIDE HYDROLASE; EPOXIDE HYDROLASE 1; HISTIDINE; LEUCINE; LYSINE; PHENYLALANINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; INDIA; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

ADULT; AGED; EPOXIDE HYDROLASES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDIA; LOGISTIC MODELS; LUNG NEOPLASMS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SMOKING;

EID: 79958203073     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2011.587070     Document Type: Article

References (39)

1. ParkinDM, Bray F, Ferlay J, Pisani P. Estimating theworld cancer burden: globocan 2000. Int J Cancer 2001;94:153-156. (Pubitemid 32911406)
2. Behera D, Balamugesh T. Lung cancer in India. Indian J Chest Dis Allied Sci 2004;46:269-281.
3. Subramanian J, Govindan R. Lung cancer in never smokers: a review. J Clin Oncol 2007;25:561-570. (Pubitemid 350002964)
4. Alberg AJ, Brock MV, Samet JM. Epidemiology of lung cancer: looking to the future. J Clin Oncol 2005;10:3175-3185. (Pubitemid 46217457)
5. Christiani DC. Genetic susceptibility to lung cancer. J Clin Oncol 2006;24:1651-1652. (Pubitemid 46622134)
6. Blot WJ, Fraumeni JF Jr. Cancers of the lung and pleura. In Cancer Epidemiology and Prevention. Schottenfield D, Fraumeni JF eds. New York: Oxford University Press, 1996, pp. 638-651.
7. Oesch F, Schottenfield D, Fraumeni JF. eds. Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds. Xenobiotica 1973;3:305-340.
8. Hassett C, Aicher L, Sidhu JS, Omiecinski CJ. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 1994;3:421-428. (Pubitemid 24083901)
9. Hirvonen A. Polymorphisms of xenobiotic metabolizing enzymes and susceptibility to cancer. Environ Health Perspect 1999;107:37-47. (Pubitemid 29164198)
10. Smith CA, Harrison DJ. Association between polymorphisms in gene for microsomal epoxide hydrolase and susceptibility to emphysema. Lancet 1997;350:630-633. (Pubitemid 27367797)
11. Benhamou S, Reinikainen M, Bouchardy C, Dayer P, Hirvonen A. Association between lung cancer and microsomal epoxide hydrolase genotypes. Cancer Res 1998;58:5291-5293. (Pubitemid 28551101)
12. Persson I, Johansson I, Lou YC, Yue QY, Duan LS, Bertilsson L, Ingelman-Sundberg M. Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patients. Int J Cancer 1999;81:325-329. (Pubitemid 29165187)
13. Wu X, Gwyn K, Amos CI, Makan N, Hong WK, Spitz MR. The association ofmicrosomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans. Carcinogenesis 2001;22:923-928. (Pubitemid 32514959)
14. Zhao H, Spitz MR, Gwyn KM,Wu X.Microsomal epoxide hydrolase polymorphisms and lung cancer risk in non-Hispanic whites. Mol Carcinogenesis 2002;33:99-104. (Pubitemid 34113198)
15. Gsur A, Zidek T, Schnattinger K, Feik E, Haidinger G, Hollaus P,Mohn-Staudner A, Armbruster C, Madersbacher S, Schatzl G, Trieb K, Vutuc C, Micksche M. Association of microsomal epoxide hydrolase polymorphisms and lung cancer risk. Br J Cancer 2003;89:702-706. (Pubitemid 37076177)
16. Gottlieb N. Indian cigarettes gain popularity, but don't let the flavor fool you. J. Natl. Cancer Inst 1999;91:1806-1807.
17. Maekawa K, Itoda M, Hanioka N, Saito Y, Murayama N, Nakajima O, Soyama A, Ishida S, Ozawa S, Ando M, Sawada J. Non-synonymous single nucleotide alterations in the microsomal epoxide hydrolase gene and their functional effects. Xenobiotica 2003;3:277-287. (Pubitemid 36408196)
18. YoshikawaM,HiyamaK, Ishioka S,MaedaH,Maeda A, Yamakido M.Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese. Int J Mol Med 2000;5:49-53.
19. Baxter SW, Choong DYH, Campbell IG.Microsomal epoxide hydrolase polymorphism and susceptibility to ovarian cancer. Cancer Lett 2002;177:75-81. (Pubitemid 34102401)
20. Hosagrahara VP, Rettie AE, Hassett C, Omiecinski CJ. Functional analysis of humanmicrosomal epoxide hydrolase genetic variants. Chem Biol Interact 2004;150:149-159. (Pubitemid 39463278)
21. Yin L, Pu Y, Liu TY, Tung YH, Chen KW, Lin P. Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China. Lung Cancer 2001;33:133-141. (Pubitemid 32707894)
22. Cajas-Salazar N, Au WW, Zwischenberger JB, Sierra-Torres CH, Salama SA, Alpard SK, Tyring SK. Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer. Cancer Genet Cytogenet 2003;145:97-102. (Pubitemid 36993738)
23. Harrison DJ, Hubbard AL, MacMillan J, Wyllie AH, Smith CA. Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer. Br J Cancer 1999;79:168-171. (Pubitemid 28566943)
24. Tiemersma EW, Omer RE, Bunschoten A, van't Veer P, Kok FJ, Idris MO, Kadaru AM, Fedail SS, Kampman E. Role of genetic polymorphismof glutathione-S-transferase T1 andmicrosomal epoxide hydrolase in aflatoxin-associated hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev 2001;10:785-791. (Pubitemid 32695158)
25. London SJ, Smart J, Daly AK. Lung cancer risk in relation to genetic polymorphisms of microsomal epoxide hydrolase among African-Americans and Caucasians in Los Angeles County. Lung Cancer 2000;28:147-155. (Pubitemid 30136414)
26. VohoaA,MetsolaaK, Anttilaa S, ImpivaarabO, Järvisaloc J, Vainioa H, Husgafvel-Pursiainena K, Hirvonen A. EPHX1 gene polymorphisms and individual susceptibility to lung cancer. Cancer Lett 2006;237:102-108.
27. Lancaster JM, Brownlee HA, Bell DA, Futreal PA, Marks JR, Berchuck A, Wiseman RW, Taylor JA. Microsomal epoxide hydrolase polymorphismas a risk factor for ovarian cancer.Mol Carcinog 1996;17:160-162. (Pubitemid 26408191)
28. Amador AG, Righi PD, Radpour S, Everett ET, Weisberger E, Langer M, Eckert GJ, Christen AG, Campbell, S Jr, Summerlin, DJ, Reynolds, N, Hartsfield, JK Jr. Polymorphisms of xenobiotic metabolizing genes in oropharyngeal carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:440-445. (Pubitemid 41124666)
29. Zhou W, Thurston SW, Liu G, Xu LL, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC. The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer. Cancer Epidemiol Biomarkers Prev 2001;10:461-466. (Pubitemid 32701631)
30. Lee WJ, Brennan P, Boffetta P, London SJ, Benhamou S, Rannug A, To-Figueras J, Ingelman-Sundberg M, Shields P, Gaspari L, Taioli E. Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review. Biomarkers 2002;7:230-241. (Pubitemid 34678838)
31. Kiyohara C, Yoshimasu K, Takayama K, Nakanishi Y. EPHX1 polymorphisms and the risk of lung cancer, a HuGE review. Epidemiology 2006;17:89-99.
32. Wynder EL, Muscat JE. The changing epidemiology of smoking and lung cancer histology. Environ Health Perspect 1995;103(Suppl 8):143-148. (Pubitemid 26040890)
33. Hoffmann D, Hoffmann I. The changing cigarette, 1950-1995. J Toxicol Environ Health 1997;50:307-364.
34. Hecht SS. Tobacco smoke carcinogens and lung cancer. JNatlCancer Inst 1999;91:1194-1210. (Pubitemid 29357186)
35. Alberg AJ, Samet JM. Epidemiology of lung cancer. Chest 2003;123:21S-49S. (Pubitemid 36135701)
36. Greenland S.The effect of misclassification in the presence of covariates. Am J Epidemiol 1980;112:564-569. (Pubitemid 10029558)
37. Hunter DJ, Hankinson SE, Hough H, Gertig DM, Garcia-Closas M, Spiegelman D, Manson JE, Colditz GA, Willett WC, Speizer FE, Kelsey K. A prospective study of NAT2 acetylation genotype, cigarette smoking, and risk of breast cancer. Carcinogenesis 1997;18:2127-2132. (Pubitemid 28134739)
38. Deng Y, Newman B, Dunne MP, Silburn PA, Mellick GD. Caseonly study of interactions between genetic polymorphisms of GSTM1, P1, T1 and Z1 and smoking in Parkinson's disease. Neurosci Lett 2004;366:326-331. (Pubitemid 39024291)
39. To-Figueras J, Gene M, Góamez-Catalan J, Pique E, Borrego N, Corbella J. Lung cancer susceptibility in relation to combined polymorphisms ofmicrosomal epoxide hydrolase and glutathione S-transferase P1. Cancer Lett 2001;173:155-162. (Pubitemid 32971933)