-
1
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465: 1084-1088.
-
Nature
, vol.465
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
Maceyka, M.7
Jiang, H.8
Luo, C.9
Kordula, T.10
Milstien, S.11
Spiegel, S.12
-
2
-
-
79551628419
-
Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: Role of sphingosine kinase 1 and S1P lyase
-
Berdyshev EV, Gorshkova I, Usatyuk P, Kalari S, Zhao Y, Pyne NJ, Pyne S, Sabbadini RA, Garcia JG, Natarajan V. Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase. PLos One 6: e16571.
-
PLos One
, vol.6
-
-
Berdyshev, E.V.1
Gorshkova, I.2
Usatyuk, P.3
Kalari, S.4
Zhao, Y.5
Pyne, N.J.6
Pyne, S.7
Sabbadini, R.A.8
Garcia, J.G.9
Natarajan, V.10
-
3
-
-
33747072117
-
De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells
-
Berdyshev EV, Gorshkova IA, Usatyuk P, Zhao Y, Saatian B, Hubbard W, Natarajan V. De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells. Cell Signal 18: 1779-1792, 2006.
-
(2006)
Cell Signal
, vol.18
, pp. 1779-1792
-
-
Berdyshev, E.V.1
Gorshkova, I.A.2
Usatyuk, P.3
Zhao, Y.4
Saatian, B.5
Hubbard, W.6
Natarajan, V.7
-
4
-
-
14844349179
-
Enhancement of intracellular sphingosine-1-phosphate production by inositol 1,4,5-trisphosphateevoked calcium mobilisation in HEK-293 cells: Endogenous sphingosine-1-phosphate as a modulator of the calcium response
-
Blom T, Slotte JP, Pitson SM, Tornquist K. Enhancement of intracellular sphingosine-1-phosphate production by inositol 1,4,5-trisphosphateevoked calcium mobilisation in HEK-293 cells: endogenous sphingosine-1-phosphate as a modulator of the calcium response. Cell Signal 17: 827-836, 2005.
-
(2005)
Cell Signal
, vol.17
, pp. 827-836
-
-
Blom, T.1
Slotte, J.P.2
Pitson, S.M.3
Tornquist, K.4
-
5
-
-
0344737630
-
Mitogen-activated protein kinases in endothelial pathophysiology
-
Bogatcheva NV, Dudek SM, Garcia JG, Verin AD. Mitogen-activated protein kinases in endothelial pathophysiology. J Investig Med 51: 341-352, 2003.
-
(2003)
J Investig Med
, vol.51
, pp. 341-352
-
-
Bogatcheva, N.V.1
Dudek, S.M.2
Garcia, J.G.3
Verin, A.D.4
-
6
-
-
70349327604
-
Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl] ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro
-
Camp SM, Bittman R, Chiang ET, Moreno-Vinasco L, Mirzapoiazova T, Sammani S, Lu X, Sun C, Harbeck M, Roe M, Natarajan V, Garcia JG, Dudek SM. Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl] ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro. J Pharmacol Exp Ther 331: 54-64,2009.
-
(2009)
J Pharmacol Exp Ther
, vol.331
, pp. 54-64
-
-
Camp, S.M.1
Bittman, R.2
Chiang, E.T.3
Moreno-Vinasco, L.4
Mirzapoiazova, T.5
Sammani, S.6
Lu, X.7
Sun, C.8
Harbeck, M.9
Roe, M.10
Natarajan, V.11
Garcia, J.G.12
Dudek, S.M.13
-
7
-
-
51349135711
-
Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane
-
Chae YC, Kim JH, Kim KL, Kim HW, Lee HY, Heo WD, Meyer T, Suh PG, Ryu SH. Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane. Mol Biol Cell 19: 3111-3123, 2008.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3111-3123
-
-
Chae, Y.C.1
Kim, J.H.2
Kim, K.L.3
Kim, H.W.4
Lee, H.Y.5
Heo, W.D.6
Meyer, T.7
Suh, P.G.8
Ryu, S.H.9
-
8
-
-
2642580994
-
Pulmonary endothelial cell barrier enhancement by sphin-gosine 1-phosphate: Roles for cortactin and myosin light chain kinase
-
Dudek SM, Jacobson JR, Chiang ET, Birukov KG, Wang P, Zhan X, Garcia JG. Pulmonary endothelial cell barrier enhancement by sphin-gosine 1-phosphate: roles for cortactin and myosin light chain kinase. J Biol Chem 279: 24692-24700, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 24692-24700
-
-
Dudek, S.M.1
Jacobson, J.R.2
Chiang, E.T.3
Birukov, K.G.4
Wang, P.5
Zhan, X.6
Garcia, J.G.7
-
9
-
-
0033738368
-
Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis
-
English D, Welch Z, Kovala AT, Harvey K, Volpert OV, Brindley DN, Garcia JG. Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. FASEB J 14: 2255-2265, 2000.
-
(2000)
FASEB J
, vol.14
, pp. 2255-2265
-
-
English, D.1
Welch, Z.2
Kovala, A.T.3
Harvey, K.4
Volpert, O.V.5
Brindley, D.N.6
Garcia, J.G.7
-
10
-
-
0034799675
-
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
-
Garcia JG, Liu F, Verin AD, Birukova A, Dechert MA, Gerthoffer WT, Bamberg JR, English D. Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. J Clin Invest 108: 689-701, 2001.
-
(2001)
J Clin Invest
, vol.108
, pp. 689-701
-
-
Garcia, J.G.1
Liu, F.2
Verin, A.D.3
Birukova, A.4
Dechert, M.A.5
Gerthoffer, W.T.6
Bamberg, J.R.7
English, D.8
-
11
-
-
0027754169
-
A morphological biosensor for mammalian cells
-
Giaever I, Keese CR. A morphological biosensor for mammalian cells. Nature 366: 591-592, 1993.
-
(1993)
Nature
, vol.366
, pp. 591-592
-
-
Giaever, I.1
Keese, C.R.2
-
12
-
-
45549098906
-
Protein kinase C-epsilon regulates sphingosine 1-phosphate-mediated migration of human lung endothelial cells through activation of phospholipase D2, protein kinase C-zeta, and Rac1
-
Gorshkova I, He D, Berdyshev E, Usatuyk P, Burns M, Kalari S, Zhao Y, Pendyala S, Garcia JG, Pyne NJ, Brindley DN, Natarajan V. Protein kinase C-epsilon regulates sphingosine 1-phosphate-mediated migration of human lung endothelial cells through activation of phospholipase D2, protein kinase C-zeta, and Rac1. J Biol Chem 283: 11794-11806, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 11794-11806
-
-
Gorshkova, I.1
He, D.2
Berdyshev, E.3
Usatuyk, P.4
Burns, M.5
Kalari, S.6
Zhao, Y.7
Pendyala, S.8
Garcia, J.G.9
Pyne, N.J.10
Brindley, D.N.11
Natarajan, V.12
-
13
-
-
69949113620
-
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate
-
Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, Singh SK, Luo C, Marmorstein R, Kordula T, Milstien S, Spiegel S. Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science 325: 1254-1257, 2009.
-
(2009)
Science
, vol.325
, pp. 1254-1257
-
-
Hait, N.C.1
Allegood, J.2
Maceyka, M.3
Strub, G.M.4
Harikumar, K.B.5
Singh, S.K.6
Luo, C.7
Marmorstein, R.8
Kordula, T.9
Milstien, S.10
Spiegel, S.11
-
14
-
-
34548831705
-
Sphingosine 1-phosphate has dual functions in the regulation of endothelial cell permeability and Ca2+ metabolism
-
Itagaki K, Yun JK, Hengst JA, Yatani A, Hauser CJ, Spolarics Z, Deitch EA. Sphingosine 1-phosphate has dual functions in the regulation of endothelial cell permeability and Ca2+ metabolism. J Pharmacol Exp Ther 323: 186-191, 2007.
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 186-191
-
-
Itagaki, K.1
Yun, J.K.2
Hengst, J.A.3
Yatani, A.4
Hauser, C.J.5
Spolarics, Z.6
Deitch, E.A.7
-
15
-
-
0028986614
-
Sphingolipid-gated Ca2+ release from intracellular stores of endothelial cells is mediated by a novel Ca(2+)-permeable channel
-
Kim S, Lakhani V, Costa DJ, Sharara AI, Fitz JG, Huang LW, Peters KG, Kindman LA. Sphingolipid-gated Ca2+ release from intracellular stores of endothelial cells is mediated by a novel Ca(2+)-permeable channel. J Biol Chem 270: 5266-5269, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 5266-5269
-
-
Kim, S.1
Lakhani, V.2
Costa, D.J.3
Sharara, A.I.4
Fitz, J.G.5
Huang, L.W.6
Peters, K.G.7
Kindman, L.A.8
-
16
-
-
0028228326
-
Characterization of a novel intracellular sphingolipid-gated Ca(2+)-permeable channel from rat basophilic leukemia cells
-
Kindman LA, Kim S, McDonald TV, Gardner P. Characterization of a novel intracellular sphingolipid-gated Ca(2+)-permeable channel from rat basophilic leukemia cells. J Biol Chem 269: 13088-13091, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 13088-13091
-
-
Kindman, L.A.1
Kim, S.2
McDonald, T.V.3
Gardner, P.4
-
17
-
-
33747307276
-
Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells
-
Lee JF, Ozaki H, Zhan X, Wang E, Hla T, Lee MJ. Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells. Histochem Cell Biol 126: 297-304, 2006.
-
(2006)
Histochem Cell Biol
, vol.126
, pp. 297-304
-
-
Lee, J.F.1
Ozaki, H.2
Zhan, X.3
Wang, E.4
Hla, T.5
Lee, M.J.6
-
18
-
-
27744547965
-
SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism
-
Maceyka M, Sankala H, Hait NC, Le Stunff H, Liu H, Toman R, Collier C, Zhang M, Satin LS, Merrill AH Jr, Milstien S, Spiegel S. SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. J Biol Chem 280: 37118-37129, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 37118-37129
-
-
Maceyka, M.1
Sankala, H.2
Hait, N.C.3
le Stunff, H.4
Liu, H.5
Toman, R.6
Collier, C.7
Zhang, M.8
Satin, L.S.9
Merrill Jr., A.H.10
Milstien, S.11
Spiegel, S.12
-
19
-
-
0029962243
-
Molecular cloning and characterization of SCaMPER, a sphingolipid Ca2+ release-mediating protein from endoplasmic reticulum
-
Mao C, Kim SH, Almenoff JS, Rudner XL, Kearney DM, Kindman LA. Molecular cloning and characterization of SCaMPER, a sphingolipid Ca2+ release-mediating protein from endoplasmic reticulum. Proc Natl Acad Sci USA 93: 1993-1996, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1993-1996
-
-
Mao, C.1
Kim, S.H.2
Almenoff, J.S.3
Rudner, X.L.4
Kearney, D.M.5
Kindman, L.A.6
-
20
-
-
0027991078
-
Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway
-
Mattie M, Brooker G, Spiegel S. Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J Biol Chem 269: 3181-3188, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 3181-3188
-
-
Mattie, M.1
Brooker, G.2
Spiegel, S.3
-
21
-
-
5644287793
-
In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: Mechanistic insights
-
McVerry BJ, Garcia JG. In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights. Cell Signal 17: 131-139, 2005.
-
(2005)
Cell Signal
, vol.17
, pp. 131-139
-
-
McVerry, B.J.1
Garcia, J.G.2
-
22
-
-
7044241285
-
Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury
-
McVerry BJ, Peng X, Hassoun PM, Sammani S, Simon BA, Garcia JG. Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. Am J Respir Crit Care Med 170: 987-993,2004.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 987-993
-
-
McVerry, B.J.1
Peng, X.2
Hassoun, P.M.3
Sammani, S.4
Simon, B.A.5
Garcia, J.G.6
-
23
-
-
20444431854
-
Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells
-
Mehta D, Konstantoulaki M, Ahmmed GU, Malik AB. Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells. J Biol Chem 280: 17320-17328, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 17320-17328
-
-
Mehta, D.1
Konstantoulaki, M.2
Ahmmed, G.U.3
Malik, A.B.4
-
24
-
-
2642630721
-
2+ signalling by G-protein-coupled receptors
-
2+ signalling by G-protein-coupled receptors. EMBO J 17: 2830-2837, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 2830-2837
-
-
Meyerzu Heringdorf, D.1
Lass, H.2
Alemany, R.3
Laser, K.T.4
Neumann, E.5
Zhang, C.6
Schmidt, M.7
Rauen, U.8
Jakobs, K.H.9
van Koppen, C.J.10
-
25
-
-
0242710592
-
Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors
-
Meyerzu Heringdorf D, Liliom K, Schaefer M, Danneberg K, Jaggar JH, Tigyi G, Jakobs KH. Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors. FEBS Lett 554: 443-449, 2003.
-
(2003)
FEBS Lett
, vol.554
, pp. 443-449
-
-
Meyerzu Heringdorf, D.1
Liliom, K.2
Schaefer, M.3
Danneberg, K.4
Jaggar, J.H.5
Tigyi, G.6
Jakobs, K.H.7
-
26
-
-
0035004561
-
Sphingosine kinase: A mediator of vital cellular functions
-
Olivera A, Spiegel S. Sphingosine kinase: a mediator of vital cellular functions. Prostaglandins Other Lipid Mediat 64: 123-134, 2001.
-
(2001)
Prostaglandins Other Lipid Mediat
, vol.64
, pp. 123-134
-
-
Olivera, A.1
Spiegel, S.2
-
27
-
-
0024913973
-
Use of image analysis to quantitate changes in form of mitochondrial DNA after x-irradiation
-
O'Neill RR, Mitchell LG, Merril CR, Rasband WS. Use of image analysis to quantitate changes in form of mitochondrial DNA after x-irradiation. Appl Theor Electrophor 1: 163-167, 1989.
-
(1989)
Appl Theor Electrophor
, vol.1
, pp. 163-167
-
-
O'Neill, R.R.1
Mitchell, L.G.2
Merril, C.R.3
Rasband, W.S.4
-
28
-
-
2542461296
-
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury
-
Peng X, Hassoun PM, Sammani S, McVerry BJ, Burne MJ, Rabb H, Pearse D, Tuder RM, Garcia JG. Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. Am J Respir Crit Care Med 169: 1245-1251, 2004.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 1245-1251
-
-
Peng, X.1
Hassoun, P.M.2
Sammani, S.3
McVerry, B.J.4
Burne, M.J.5
Rabb, H.6
Pearse, D.7
Tuder, R.M.8
Garcia, J.G.9
-
29
-
-
49949086461
-
Sphingosine 1-phosphate, lysophosphatidic acid and growth factor signaling and termination
-
Pyne NJ, Pyne S. Sphingosine 1-phosphate, lysophosphatidic acid and growth factor signaling and termination. Biochim Biophys Acta 1781: 467-476, 2008.
-
(2008)
Biochim Biophys Acta
, vol.1781
, pp. 467-476
-
-
Pyne, N.J.1
Pyne, S.2
-
30
-
-
28844452498
-
Lipid phosphate phosphatases and lipid phosphate signalling
-
Pyne S, Long JS, Ktistakis NT, Pyne NJ. Lipid phosphate phosphatases and lipid phosphate signalling. Biochem Soc Trans 33: 1370-1374, 2005.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 1370-1374
-
-
Pyne, S.1
Long, J.S.2
Ktistakis, N.T.3
Pyne, N.J.4
-
31
-
-
0037162033
-
Sphingosine 1-phosphate signalling and termination at lipid phosphate receptors
-
Pyne S, Pyne NJ. Sphingosine 1-phosphate signalling and termination at lipid phosphate receptors. Biochim Biophys Acta 1582: 121-131,2002.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 121-131
-
-
Pyne, S.1
Pyne, N.J.2
-
32
-
-
0032492696
-
Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate-caged SPP
-
Qiao L, Kozikowski AP, Olivera A, Spiegel S. Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate-caged SPP. Bioorg Med Chem Lett 8: 711-714, 1998.
-
(1998)
Bioorg Med Chem Lett
, vol.8
, pp. 711-714
-
-
Qiao, L.1
Kozikowski, A.P.2
Olivera, A.3
Spiegel, S.4
-
33
-
-
77952327561
-
Differential Effects of S1P Receptors on Airway and Vascular Barrier Function in the Murine Lung
-
Sammani S, Moreno-Vinasco L, Mirzapoiazova T, Singleton PA, Chiang ET, Evenoski CL, Wang T, Mathew B, Husain A, Moitra J, Sun X, Nunez L, Jacobson JR, Dudek SM, Natarajan V, Garcia JG. Differential Effects of S1P Receptors on Airway and Vascular Barrier Function in the Murine Lung. Am J Respir Cell Mol Biol 43: 394-402,2009.
-
(2009)
Am J Respir Cell Mol Biol
, vol.43
, pp. 394-402
-
-
Sammani, S.1
Moreno-Vinasco, L.2
Mirzapoiazova, T.3
Singleton, P.A.4
Chiang, E.T.5
Evenoski, C.L.6
Wang, T.7
Mathew, B.8
Husain, A.9
Moitra, J.10
Sun, X.11
Nunez, L.12
Jacobson, J.R.13
Dudek, S.M.14
Natarajan, V.15
Garcia, J.G.16
-
34
-
-
0037636489
-
Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products
-
Schaphorst KL, Chiang E, Jacobs KN, Zaiman A, Natarajan V, Wigley F, Garcia JG. Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products. Am J Physiol Lung Cell Mol Physiol 285: L258-L267, 2003.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
-
-
Schaphorst, K.L.1
Chiang, E.2
Jacobs, K.N.3
Zaiman, A.4
Natarajan, V.5
Wigley, F.6
Garcia, J.G.7
-
35
-
-
33645847450
-
Sphingosine-1-phosphate-induced intracellular Ca2+ mobilization in human endothelial cells
-
Seol GH, Kim MY, Liang GH, Kim JA, Kim YJ, Oh S, Suh SH. Sphingosine-1-phosphate-induced intracellular Ca2+ mobilization in human endothelial cells. Endothelium 12: 263-269, 2005.
-
(2005)
Endothelium
, vol.12
, pp. 263-269
-
-
Seol, G.H.1
Kim, M.Y.2
Liang, G.H.3
Kim, J.A.4
Kim, Y.J.5
Oh, S.6
Suh, S.H.7
-
36
-
-
26444551684
-
Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin
-
Singleton PA, Dudek SM, Chiang ET, Garcia JG. Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin. FASEB J 19: 1646-1656, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 1646-1656
-
-
Singleton, P.A.1
Dudek, S.M.2
Chiang, E.T.3
Garcia, J.G.4
-
37
-
-
0346788900
-
Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways
-
Spiegel S, Milstien S. Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways. Biochem Soc Trans 31: 1216-1219, 2003.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1216-1219
-
-
Spiegel, S.1
Milstien, S.2
-
38
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
Spiegel S, Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 4: 397-407, 2003.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
39
-
-
78049502852
-
Extracellular and intracellular actions of sphingosine-1-phosphate
-
Strub GM, Maceyka M, Hait NC, Milstien S, Spiegel S. Extracellular and intracellular actions of sphingosine-1-phosphate. Adv Exp Med Biol 688: 141-155.
-
Adv Exp Med Biol
, vol.688
, pp. 141-155
-
-
Strub, G.M.1
Maceyka, M.2
Hait, N.C.3
Milstien, S.4
Spiegel, S.5
-
40
-
-
58149174403
-
Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells
-
Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D. Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circ Res 103: 1164-1172, 2008.
-
(2008)
Circ Res
, vol.103
, pp. 1164-1172
-
-
Tauseef, M.1
Kini, V.2
Knezevic, N.3
Brannan, M.4
Ramchandaran, R.5
Fyrst, H.6
Saba, J.7
Vogel, S.M.8
Malik, A.B.9
Mehta, D.10
-
41
-
-
33750620307
-
Ca2+ signaling, TRP channels, and endothelial permeability
-
Tiruppathi C, Ahmmed GU, Vogel SM, Malik AB. Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation 13: 693-708, 2006.
-
(2006)
Microcirculation
, vol.13
, pp. 693-708
-
-
Tiruppathi, C.1
Ahmmed, G.U.2
Vogel, S.M.3
Malik, A.B.4
-
42
-
-
0042845703
-
Role of Ca2+ signaling in the regulation of endothelial permeability
-
Tiruppathi C, Minshall RD, Paria BC, Vogel SM, Malik AB. Role of Ca2+ signaling in the regulation of endothelial permeability. Vascul Pharmacol 39: 173-185, 2002.
-
(2002)
Vascul Pharmacol
, vol.39
, pp. 173-185
-
-
Tiruppathi, C.1
Minshall, R.D.2
Paria, B.C.3
Vogel, S.M.4
Malik, A.B.5
-
43
-
-
0032949486
-
Assessment of the extracellular and intracellular actions of sphingosine 1-phosphate by using the p42/p44 mitogen-activated protein kinase cascade as a model
-
Tolan D, Conway AM, Rakhit S, Pyne N, Pyne S. Assessment of the extracellular and intracellular actions of sphingosine 1-phosphate by using the p42/p44 mitogen-activated protein kinase cascade as a model. Cell Signal 11: 349-354, 1999.
-
(1999)
Cell Signal
, vol.11
, pp. 349-354
-
-
Tolan, D.1
Conway, A.M.2
Rakhit, S.3
Pyne, N.4
Pyne, S.5
-
44
-
-
52049115702
-
Dissociation of Rac1(GDP) RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP
-
Ugolev Y, Berdichevsky Y, Weinbaum C, Pick E. Dissociation of Rac1(GDP) RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP. J Biol Chem 283: 22257-22271, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 22257-22271
-
-
Ugolev, Y.1
Berdichevsky, Y.2
Weinbaum, C.3
Pick, E.4
-
46
-
-
67649304855
-
Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells
-
Usatyuk PV, Gorshkova IA, He D, Zhao Y, Kalari SK, Garcia JG, Natarajan V. Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells. J Biol Chem 284: 15339-15352, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 15339-15352
-
-
Usatyuk, P.V.1
Gorshkova, I.A.2
He, D.3
Zhao, Y.4
Kalari, S.K.5
Garcia, J.G.6
Natarajan, V.7
-
47
-
-
0033572248
-
Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors
-
Wang F, Van Brocklyn JR, Edsall L, Nava VE, Spiegel S. Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors. Cancer Res 59: 6185-6191,1999.
-
(1999)
Cancer Res
, vol.59
, pp. 6185-6191
-
-
Wang, F.1
van Brocklyn, J.R.2
Edsall, L.3
Nava, V.E.4
Spiegel, S.5
-
48
-
-
0036845015
-
Involvement of phospholipases D1 and D2 in sphingosine 1-phosphate-induced ERK (extracellular-signal-regulated kinase) activation and interleukin-8 secretion in human bronchial epithelial cells
-
Wang L, Cummings R, Usatyuk P, Morris A, Irani K, Natarajan V. Involvement of phospholipases D1 and D2 in sphingosine 1-phosphate-induced ERK (extracellular-signal-regulated kinase) activation and interleukin-8 secretion in human bronchial epithelial cells. Biochem J 367: 751-760, 2002.
-
(2002)
Biochem J
, vol.367
, pp. 751-760
-
-
Wang, L.1
Cummings, R.2
Usatyuk, P.3
Morris, A.4
Irani, K.5
Natarajan, V.6
-
49
-
-
0029079324
-
Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism
-
Wu J, Spiegel S, Sturgill TW. Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism. J Biol Chem 270: 11484-11488, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 11484-11488
-
-
Wu, J.1
Spiegel, S.2
Sturgill, T.W.3
-
50
-
-
0035130986
-
Intracellular sphingosine 1-phosphate production: A novel pathway for Ca2+ release
-
Young KW, Nahorski SR. Intracellular sphingosine 1-phosphate production: a novel pathway for Ca2+ release. Semin Cell Dev Biol 12: 19-25, 2001.
-
(2001)
Semin Cell Dev Biol
, vol.12
, pp. 19-25
-
-
Young, K.W.1
Nahorski, S.R.2
-
51
-
-
0036878818
-
Sphingosine 1-phosphate: A Ca2+ release mediator in the balance
-
Young KW, Nahorski SR. Sphingosine 1-phosphate: a Ca2+ release mediator in the balance. Cell Calcium 32: 335-341, 2002.
-
(2002)
Cell Calcium
, vol.32
, pp. 335-341
-
-
Young, K.W.1
Nahorski, S.R.2
-
52
-
-
80051658461
-
Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression
-
In Press
-
Zhao Y, Gorshkova IA, Berdyshev E, He D, Fu P, Ma W, Su Y, Usatyuk PV, Pendyala S, Oskouian B, Saba JD, Garcia JG, Natarajan V. Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression. Am J Respir Cell Mol Biol. In Press.
-
Am J Respir Cell Mol Biol
-
-
Zhao, Y.1
Gorshkova, I.A.2
Berdyshev, E.3
He, D.4
Fu, P.5
Ma, W.6
Su, Y.7
Usatyuk, P.V.8
Pendyala, S.9
Oskouian, B.10
Saba, J.D.11
Garcia, J.G.12
Natarajan, V.13
-
53
-
-
34347250824
-
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: Role of lipid phosphate phosphatase-1 and sphingosine kinase 1
-
Zhao Y, Kalari SK, Usatyuk PV, Gorshkova I, He D, Watkins T, Brindley DN, Sun C, Bittman R, Garcia JG, Berdyshev EV, Natarajan V. Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. J Biol Chem 282: 14165-14177, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 14165-14177
-
-
Zhao, Y.1
Kalari, S.K.2
Usatyuk, P.V.3
Gorshkova, I.4
He, D.5
Watkins, T.6
Brindley, D.N.7
Sun, C.8
Bittman, R.9
Garcia, J.G.10
Berdyshev, E.V.11
Natarajan, V.12
|