1H magnetic resonance spectroscopy metabolites as biomarkers for cell cycle arrest and cell death in rat glioma cells

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 7, 2011, Pages 990-1001

  Mirbahai, Ladan ^a   Wilson, Martin ^a   Shaw, Christopher S ^a   McConville, Carmel ^a   Malcomson, Roger D G ^b   Griffin, Julian L ^c   Kauppinen, Risto A ^d   Peet, Andrew C ^a,b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^c Hopkins Building ^*  (United Kingdom)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

1H magic angle spinning NMR spectroscopy; Biomarkers; Cell growth arrest; Metabolite alterations; Necrosis

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ALANINE; ANNEXIN; CISPLATIN; DNA; GLUTAMIC ACID; GLYCEROPHOSPHORYLCHOLINE; GLYCINE; LACTIC ACID; PHOSPHATE BUFFERED SALINE; PHOSPHORYLCHOLINE; PROPIDIUM IODIDE; SUCCINIC ACID; TAURINE; AMINO ACID; PROTON; TUMOR MARKER;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PHASE; CELL DEATH; CELL STRESS; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; GLIOMA CELL; IN VITRO STUDY; IN VIVO STUDY; METABOLITE; NANOPROBE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STARVATION; TREATMENT RESPONSE; ANIMAL; DRUG EFFECT; GLIOMA; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TUMOR CELL LINE;

RATTUS;

AMINO ACIDS; ANIMALS; CELL DEATH; CELL LINE, TUMOR; CISPLATIN; G1 PHASE; GLIOMA; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORYLCHOLINE; PROTONS; RATS; SUCCINIC ACID; TUMOR MARKERS, BIOLOGICAL;

EID: 79958168516     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.07.002     Document Type: Article

References (37)

1. 1H nuclear magnetic resonance spectroscopy: effect of 5-fluorouracil on lactate levels in radiation-induced fibrosarcoma 1 tumors Cancer Res 58 1998 1063 1067 (Pubitemid 28182480)
2. L. Bogin, M.Z. Papa, S. Polak-Charcon, and H. Degani TNF-induced modulations of phospholipid metabolism in human breast cancer cells Biochim Biophys Acta 1392 1998 217 232 (Pubitemid 28287326)
3. K.M. Brindle Detection of apoptosis in tumors using magnetic resonance imaging and spectroscopy Adv Enzyme Regul 42 2002 101 112 (Pubitemid 35033532)
4. 1H magnetic resonance spectroscopy in the definition of malignancy grading of human neuroepithelial brain tumours Acta Neurochir Suppl 68 1997 127 132
5. 1H MRS analysis of human brain tumors Anticancer Res 16 1996 1559 1563 (Pubitemid 26257827)
6. N.P. Davies, M. Wilson, L.M. Harris, K. Natarajan, S. Lateef, and L. Macpherson Identification and characterisation of childhood cerebellar tumours by in vivo proton MRS NMR Biomed 21 2008 908 918
7. 1H MRS at 1.5 Tesla and ex-vivo high-resolution magic-angle spinning NMR NMR Biomed 23 2010 80 87
8. 1H NMR spectroscopy and reverse transcription-PCR analysis of apoptosis in a rat glioma Anal Chem 78 2006 1546 1552 (Pubitemid 43346292)
9. J.L. Griffin, and J.P. Shockcor Metabolic profiles of cancer cells Nat Rev Cancer 4 2004 551 561 (Pubitemid 38868624)
10. M.L. Gyngell, M. Hoehn-Berlage, O. Kloiber, T. Michaelis, R.I. Ernestus, and D. Horstermann Localized proton NMR spectroscopy of experimental gliomas in rat brain in vivo NMR Biomed 5 1992 335 340
11. 1H NMR visible lipids in the life and death of cells Trends Biochem Sci 25 2000 357 362 (Pubitemid 30497239)
12. 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis Nat Med 5 1999 1323 1327 (Pubitemid 29535613)
13. L.M. Harris, N.P. Davies, L. Macpherson, S. Lateef, K. Natarajan, and M.A. Brundler Magnetic resonance spectroscopy in the assessment of pilocytic astrocytomas Eur J Cancer 44 2008 2640 2647
14. T. Hirakawa, K. Maruyama, N.E. Kohl, T. Kodama, and H.E. Ruley Massive accumulation of neutral lipids in cells conditionally transformed by an activated H-ras oncogene Oncogene 6 1991 289 295 (Pubitemid 21902675)
15. R.A. Kauppinen, and S.R. Williams Nuclear magnetic resonance spectroscopy studies of the brain Prog Neurobiol 44 1994 87 118 (Pubitemid 24297292)
16. A. Kovlanikaya, A. Panigrahy, M.D. Krieger, I. Gonzalez-Gomez, N. Ghugre, and J.G. McComb Untreated pediatric primitive neuroectodermal tumour in vivo: quantitation of taurine with MR spectroscopy Radiology 236 2005 1020 1025 (Pubitemid 41170867)
17. 1H NMR spectroscopic investigation NMR Biomed 18 2005 371 382 (Pubitemid 41410357)
18. 31P-MR spectroscopy of primary and recurrent human brain tumors in vitro: malignancy-characteristic profiles of water soluble and lipophilic spectral components NMR Biomed 14 2001 307 317 (Pubitemid 32782844)
19. 1H NMR spectroscopy in vivo, ex vivo, and in vitro J Biol Chem 278 2003 45915 45923 (Pubitemid 37432737)
20. M. Lindskog, C. Spenger, J. Jarvet, A. Graslund, and P. Kogner Predicting resistance or response to chemotherapy by proton magnetic resonance spectroscopy in neuroblastoma J Natl Cancer Inst 96 2004 1457 1466 (Pubitemid 39429670)
21. N.W. Lutz From metabolic to metabolomic NMR spectroscopy of apoptotic cells Metabolomics 1 2005 251 268
22. N.W. Lutz, M.E. Tome, and P.J. Cozzone Early changes in glucose and phospholipid metabolism following apoptosis induction by IFN-gamma/TNF-alpha in HT-29 cells FEBS Lett 544 2003 123 128 (Pubitemid 36628047)
23. 1H magnetic resonance spectroscopy Neoplasia 8 2006 560 567 (Pubitemid 44061311)
24. 1H MR spectroscopy - a pilot study at 4 T Radiology 233 2004 424 431 (Pubitemid 39423801)
25. M. Milkevitch, H. Shim, U. Pilatus, S. Pickup, J.P. Wehrle, and D. Samid Increases in NMR-visible lipid and glycerophosphocholine during phenylbutyrate-induced apoptosis in human prostate cancer cells Biochim Biophys Acta 1734 2005 1 12 (Pubitemid 40615215)
26. 31P NMR spectroscopy of cell extracts Magn Reson Med 58 2007 270 280 (Pubitemid 47267644)
27. K.S. Opstad, B.A. Bell, J.R. Griffiths, and F.A. Howe Taurine: a potential marker of apoptosis in gliomas Br J Cancer 100 2009 789 794
28. F. Podo Tumour phospholipid metabolism NMR Biomed 12 1999 413 439 (Pubitemid 30016999)
29. H. Poptani, N. Bansal, R.A. Graham, A. Mancuso, D.S. Nelson, and J.D. Glickson Detecting early response to cyclophosphamide treatment of RIF-1 tumors using selective multiple quantum spectroscopy (SelMQC) and dynamic contrast enhanced imaging NMR Biomed 16 2003 102 111 (Pubitemid 36582229)
30. G. Reynolds, M. Wilson, A. Peet, and T.N. Arvanitis An algorithm for the automated quantitation of metabolites in in vitro NMR signals Magn Reson Med 56 2006 1211 1219 (Pubitemid 44865302)
31. 1H magnetic resonance spectroscopy and amino acid analysis Clin Cancer Res 6 2000 3983 3993
32. S.M. Ronen, F. DiStefano, C.L. McCoy, D. Robertson, T.A. Smith, and N.M. Al-Saffar Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis Br J Cancer 80 1999 1035 1041 (Pubitemid 29233925)
33. 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma NMR Biomed 18 2005 252 259 (Pubitemid 40936445)
34. R.L. Wahl, K. Zasadny, M. Helvie, G.D. Hutchins, B. Weber, and R. Cody Metabolic monitoring of breast cancer chemohormonotherapy using positron emission tomography: initial evaluation J Clin Oncol 11 1993 2101 2111 (Pubitemid 23332245)
35. S. Wiklund, E. Johansson, L. Sjostrom, E.J. Mellerowicz, U. Edlund, and J.P. Shockcor Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models Anal Chem 80 2008 115 122 (Pubitemid 351448411)
36. 31P MRS Magn Reson Med 40 1998 411 420 (Pubitemid 28391902)
37. W.X. Zong, and C.B. Thompson Necrotic death as a cell fate Genes Dev 20 2006 1 15 (Pubitemid 43042662)