Differentiation of glioblastoma multiforme from astrocytomas by in vitro 1H MRS analysis of human brain tumors

Anticancer Research

Volumn 16, Issue 3 B, 1996, Pages 1559-1563

  Carpinelli, Giulia ^a   Carapella, Carmine M ^b   Palombi, Laura ^a   Raus, Laura ^b   Caroli, Fabrizio ^b   Podo, Franca ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

1H Magnetic Resonance Spectroscopy; Astrocytomas; Choline; Glioblastoma multiforme; Glycine

Indexed keywords

CREATINE; CREATINE PHOSPHATE; GLYCINE; N ACETYLASPARTIC ACID;

ASTROCYTOMA; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; DIFFERENTIAL DIAGNOSIS; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; OLIGODENDROGLIOMA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ASTROCYTOMA; BRAIN NEOPLASMS; CHOLINE; DIAGNOSIS, DIFFERENTIAL; GLIOBLASTOMA; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOCREATINE;

EID: 0030057888     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (23)

1. Gill S, Thomas DGT, Van Bruggen N, Gadian DG, Peden CJ, Bell JD, Cox IJ, Menon DK, Iles RA, Bryant DJ and Coults GA: Proton MR spectroscopy of intracranial tumors: in vivo and in vitro studies. J Comput Assist Tomogr 14: 497-504, 1940.
2. 1H-NMR spectroscopic imaging. Magn Reson Med 13: 62-76, 1990.
3. Frahm J, Bruhn H, Gyngell ML, Merboldt KD, Hanicke W and Sauter R: Localized high resolution proton NMR spectroscopy using stimulated echoes: initial applications to human brain in vivo. Magn Reson Med 9: 79-93, 1989.
4. Negendank W: Studies of human tumors by MRS: a Review. NMR in Biomed 5: 303-324, 1992.
5. Kinoshita Y, Kajiwara H, Yocota A and Koga Y: Proton magnetic resonance spectroscopy of brain tumors: an in vitro study. Neurosurg 35: 606-614, 1994.
6. 1H NMR spectroscopy in vivo and in vitro. J Neurochem 63: 1538-1543, 1994.
7. 31P NMR study. FEBS Lett, 176: 88-92, 1984.
8. Leach M, Le Moyec L and Podo F: MRS of Tumours: basic principles In: de Certaines JD, Bovée WMMJ, Podo F. (Eds), MR Spectroscopy in biology and medicine. Pergamon Press 1992, 295-344.
9. 31P MRS of experimental tumors: Review Paper. NMR in Biomed 6: 345-365, 1993.
10. Negendank W, Sauter R, Brown TR, Evelhoch JL, Falini A, Gotsis ED, Heerchap A, Kamada K, Lee BCP, Mengeot MM, Mose E, Padavic-Shaller KA, Sanders JA, Spraggins TA, Stillman AE, Terwey B, Vogl TJ. Wieklow K and Zimmerman RA: Proton MR Spectroscopy in patients with glial tumor: A multicenter study. J Neurosurgery: in press, 1996.
11. Kleihues P ,Burger PC and Scheithauer BW: Histological typing of tumours of the central nervous system. WHO Blue Book, 2nd ed, Springer, pp 1-37, 1993.
12. Podo F, Carpinelli G, Di Vito M, Giannini M, Proietti E, Fiers W, Gresser I and Belardelli F: Nuclear magnetic resonance analysis of tumor necrosis factor-induced alteration of phospholipid metabolites and pH in friend leukemia cell tumors and fibrosarcomas in mice. Cancer Res 47: 6481-6489, 1987.
13. Lowry OH, Rosebrough NJ, Lewis Farr A and Randall RJ: Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275, 1951.
14. Preul MC, Caramanos Z, Collins DL, Vellemure JG, Arnold DL: Linear discriminant analysis based on proton spectroscopy imaging of human brain tumors improves pre-operative diagnosis. Second Annual Meeting of the Society of Magnetic Resonance. Abstr., p, 125, 1994.
15. Schiffer D and Vigliani MC: Prognostic factors in oligodendrogliomas. Crit Rev Neurosurg 3: 59-65, 1993.
16. Sato K, Yoshida S, Fujiwara K, Tada K, Tohyama M: Glycine cleavage system in astrocytes. Brain Res 567: 64-70, 1991.
17. Davidoff RA, Shank RP, Graham LT, Aprison MH and Werman R: Is glycine a neurotrasmitter? Nature 214: 680-683, 1967.
18. Johnson JW and Ascher P: Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325: 529-531, 1987.
19. Henn FA: Neurotrasmission and glial cells: a functional relationship? J Neurosci Res 2: 271-282, 1976.
20. Kohl RL, Perez-Polo JR and Quay WB: Effect of methionine, glycine and serine hydroximethyltranspherase activity in rat glioma and human neuroblastoma cells. J Neurosci Res 5: 271-280, 1980.
21. Nicklas WJ and Browning ET: Amino acid metabolism in glial cells: homeostatic regulation of intra- and extracellular milieu by C6 glioma cells. J Neurochem 30: 163-171, 1988.
22. 1H MR spectroscopy. NMR Biomed 7: 172-180, 1994.
23. Tohyma T, Lee VMY and Trojanowski J: Co-expression of low molecular weight neurofilament protein and glial fibrillary acidic protein in established human glioma cell lines. Am J Pathol 142: 823-892, 1993.