Metabolite Changes in BT4C Rat Gliomas Undergoing Ganciclovir-Thymidine Kinase Gene Therapy-induced Programmed Cell Death as Studied by 1H NMR Spectroscopy in Vivo, ex Vivo, and in Vitro

Journal of Biological Chemistry

Volumn 278, Issue 46, 2003, Pages 45915-45923

  Lehtimäki, Kimmo K ^a   Valonen, Piia K ^a   Griffin, Julian L ^b   Väisänen, Tuula H ^a   Gröhn, Olli H J ^a   Kettunen, Mikko I ^a   Vepsäläinen, Jouko ^a   Ylä Herttuala, Seppo ^a   Nicholson, Jeremy ^b   Kauppinen, Risto A ^a,c  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; LIPIDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TUMORS;

CELL DEATH; GENE THERAPY; HIGH RESOLUTION MAGIC ANGLE SPINNING (HRMAS);

BIOCHEMISTRY;

ADENOSINE; CHOLINE DERIVATIVE; CREATINE; GANCICLOVIR; GLYCEROPHOSPHORYLCHOLINE; GLYCINE; LIPID; MEMBRANE LIPID; PHOSPHOLIPID; PHOSPHORYLCHOLINE; TAURINE; THYMIDINE KINASE; TRIACYLGLYCEROL; URIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DENSITY; CELL LOSS; CONTROLLED STUDY; FEMALE; GENE THERAPY; GLIOMA; METABOLITE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; BRAIN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CHOLINE; DIFFUSION; GANCICLOVIR; GENE THERAPY; GLIOMA; LIPID METABOLISM; MAGNETIC RESONANCE SPECTROSCOPY; PERCHLORIC ACID; PHOSPHORYLCHOLINE; RATS; TAURINE; THYMIDINE KINASE;

ANIMALIA;

EID: 0242496187     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306209200     Document Type: Article

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