Anesthetic ketamine impairs rats' recall of previous information: The nitric oxide synthase inhibitor N-nitro-l-arginine methylester antagonizes this ketamine-induced recognition memory deficit

Anesthesiology

Volumn 114, Issue 6, 2011, Pages 1345-1353

  Boultadakis, Antonios ^a   Pitsikas, Nikolaos ^a  

^a UNIVERSITY OF THESSALY   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

KETAMINE; N(G) NITROARGININE METHYL ESTER;

ANESTHESIA; ANIMAL EXPERIMENT; COGNITIVE DEFECT; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; ENVIRONMENTAL TEMPERATURE; MALE; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; RAT; RECALL; RECOGNITION; TASK PERFORMANCE; TEMPERATURE DEPENDENCE; TRAINING;

EID: 79958158729     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e318219524e     Document Type: Conference Paper

References (35)

1. Javitt DC, Zukin SR: Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 1991; 148:1301-8.
2. Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB, Charney DS: Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 1994; 51:199-214. (Pubitemid 24081509)
3. Yamakura T, Chavez-Noriega LE, Harris RA: Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine. ANESTHESIOLOGY 2000; 92:1144-53.
4. Corssen G, Domino EF: Dissociative anesthesia: Further pharmacologic studies and first clinical experience with the phencyclidine derivative CI-581. Anesth Analg 1966; 45: 29-40.
5. Okon T: Ketamine: An introduction for the pain and palliative medicine physician. Pain Physician 2007; 10:493-500. (Pubitemid 46971302)
6. Gerlai R, McNamara A: Anesthesia induced retrograde amnesia is ameliorated by ephrinA5-IgG in mice: EphA receptor tyrosine kinases are involved in mammalian memory. Behav Brain Res 2000; 108:133-43. (Pubitemid 30084830)
7. Wang JH, Fu Y, Wilson FA, Ma YY: Ketamine affects memory consolidation: Differential effects in T-maze and passive avoidance paradigms in mice. Neuroscience 2006; 140:993-1002. (Pubitemid 43767446)
8. Meneses A: Do serotonin(1-7) receptors modulate short and long-term memory? Neurobiol Learn Mem 2007; 87:561-72. (Pubitemid 46505109)
9. Pitsikas N, Boultadakis A: Pre-training administration of anesthetic ketamine differentially affects rats' spatial and non-spatial recognition memory. Neuropharmacology 2009; 57:1-7.
10. Garthwaite J: Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci 1991; 14:60-7.
11. Bulutcu F, Dogrul A, Güç MO: The involvement of nitric oxide in the analgesic effects of ketamine. Life Sci 2002; 71:841-53. (Pubitemid 34632691)
12. Wang C, Sadovova N, Patterson TA, Zou X, Fu X, Hanig JP, Paule MG, Ali SF, Zhang X, Slikker W Jr: Protective effects of 7-nitroindazole on ketamine-induced neurotoxicity in rat forebrain culture. Neurotoxicology 2008; 29:613-20.
13. Wu J, Kikuchi T, Wang Y, Sato K, Okumura F: NOx-concentrations in the rat hippocampus and striatum have no direct relationship to anaesthesia induced by ketamine. Br J Anaesth 2000; 84:183-9. (Pubitemid 30060302)
14. Boultadakis A, Pitsikas N: Effects of the nitric oxide synthase inhibitor L-NAME on recognition and spatial memory deficits produced by different NMDA receptor antagonists in the rat. Neuropsychopharmacology 2010; 35:2357-66.
15. Ennaceur A, Delacour J: A new one-trial test for neurobiological studies of memory in rats: I. Behavioral data. Behav Brain Res 1988; 31:47-59.
16. Boultadakis A, Georgiadou G, Pitsikas N: Effects of the nitric oxide synthase inhibitor L-NAME on different memory components as assessed in the object recognition task in the rat. Behav Brain Res 2010; 207:208-14.
17. Cavoy A, Delacour J: Spatial but not object recognition is impaired by aging in rats. Physiol Behav 1993; 53:527-30. (Pubitemid 23080576)
18. Pitsikas N, Rigamonti AE, Cella SG, Muller EE: Molsidomine attenuates N(omega)-nitro-L-argininmethylester-induced deficits in a memory task in the rat. Eur J Pharmacol 2002; 452:83-6. (Pubitemid 35248127)
19. Pitsikas N, Rigamonti AE, Bonomo SM, Cella SG, Muller EE: Molsidomine antagonizes L-NAME-induced acquisition deficits in a recognition memory task in the rat. Pharmacol Res 2003; 47:311-5. (Pubitemid 36315753)
20. Fejgin K, Pålsson E, Wass C, Svensson L, Klamer D: Nitric oxide signaling in the medial prefrontal cortex is involved in the biochemical and behavioral effects of phencyclidine. Neuropsychopharmacology 2008; 33:1874-83.
21. Contestabile A, Monti B, Contestabile A, Ciani E: Brain nitric oxide and its dual effect in neuroprotection/neurodegeneration: Understanding molecular mechanisms to devise drug approaches. Curr Med Chem 2003; 10:1241-53.
22. Moghaddam B, Adams B, Verma A, Daly D: Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci 1997; 17:2921-7. (Pubitemid 27155025)
23. Shimoyama M, Shimoyama N, Inturrisi CE, Elliott K: Oral ketamine produces a dose-dependent VNS depression in the rat. Life Sci 1997; 60:9-14.
24. Minamisawa H, Nordström CH, Smith ML, Siesjö BK: The influence of the mild body and brain hypothermia on ischemic brain damage. J Cereb Blood Flow Metab 1990; 10: 365-74. (Pubitemid 20144616)
25. Busto R, Globus MY, Dietrich WD, Martinez E, Valdés I, Ginsberg MD: Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke 1989; 20:904-10.
26. Nakashima K, Todd MM: Effects of hypothermia on the rate of excitatory amino acid release after ischemic depolarization. Stroke 1996; 27:913-8. (Pubitemid 26142523)
27. Himmelseher S, Durieux ME: Revising a dogma: Ketamine for patients with neurological injury? Anesth Analg 2005; 101: 524-34, table of contents. (Pubitemid 41045240)
28. Irifune M, Shimizu T, Nomoto M, Fukuda T: Ketamine-induced anesthesia involves the N-methyl-D-aspartate receptorchannel complex in mice. Brain Res 1992; 596:1-9.
29. Hevers W, Hadley SH, Lüddens H, Amin J: Ketamine, but not phencyclidine, selectively modulates cerebellar GABA(A) receptors containing alpha6 and delta subunits. J Neurosci 2008; 28:5383-93.
30. Irifune M, Sato T, Kamata Y, Nishikawa T, Dohi T, Kawahara M: Evidence for GABA(A) receptor agonistic properties of ketamine: Convulsive and anesthetic behavioral models in mice. Anesth Analg 2000; 91:230-6. (Pubitemid 30437092)
31. Coates KM, Flood P: Ketamine and its preservative, benzethonium chloride, both inhibit human recombinant alpha7 and alpha4beta2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes. Br J Pharmacol 2001; 134:871-9. (Pubitemid 33016159)
32. Peng S, Zhang Y, Zhang J, Wang H, Ren B: Effect of ketamine on ERK expression in hippocampal neural cell and the ability of learning behavior in minor rats. Mol Biol Rep 2010; 97:3137-42.
33. Rees DD, Palmer RM, Schulz R, Hodson HF, Moncada S: Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and vivo. Br J Pharmacol 1990; 101:746-52. (Pubitemid 20357206)
34. Almeida MC, Branco LG: Role of nitric oxide in insulin-induced hypothermia in rats. Brain Res Bull 2001; 54:49-53. (Pubitemid 32156915)
35. Benamar K, Xin L, Geller EB, Adler MW: Effect of central and peripheral administration of a nitric oxide synthase inhibitor on morphine hyperthermia in rats. Brain Res 2001; 894: 266-73 (Pubitemid 32217757)