NOx- concentrations in the rat hippocampus and striatum have no direct relationship to anaesthesia induced by ketamine

British Journal of Anaesthesia

Volumn 84, Issue 2, 2000, Pages 183-189

  Wu, J ^a   Kikuchi, T ^a   Wang, Y ^a   Sato, K ^a   Okumura, F ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Anaesthetics i.v.; Brain; Hippocampus; Ketamine; Measurement techniques; Microdialysis; Nitric oxide; Pharmacology; Rat; Striatum

Indexed keywords

KETAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; CORNEA REFLEX; CORPUS STRIATUM; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RIGHTING REFLEX;

EID: 0033978209     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.bja.a013401     Document Type: Article

References (35)

1. Garthwaite J. Glutamate. Nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci 1991; 14: 60-7
2. Johns RA, Moscicki JC, DiFazio CA. Nitric oxide synthase inhibitor dose-dependently and reversibly reduces the threshold for halothane anaesthesia: a role for nitric oxide in mediating consciousness? Anesthesiology 1992; 77: 779-84
3. Nakamura K, Mori K. Nitric oxide and anesthesia. Anesth Analg 1993: 77: 877-9
4. Luo D, Leung E, Vincent SR. Nitric oxide-dependent efflux of cGMP in rat cerebellar cortex: an in vivo microdialysis study. J Neurosci 1994; 14: 263-71
5. Mantz J, Cheramy A, Thierry AM, Glowinski J, Desmonts JM. Anesthetic properties of riluzole (54274 RP), a new inhibitor of glutamate neurotransmission. Anesthesiology 1992; 76: 844-8
6. France CP, Snyder AM, Woods JH. Analgesic effects of phencyclidine-like drugs in rhesus monkeys. J Pharmacol Exp Ther 1989; 250: 197-201
7. Daniell LC. The noncompetitive N-methyl-D-aspartate antagonists, MK-801, phencyclidine and ketamine increase the potency of general anesthetics. Pharmacol Biochem Behav 1990; 36: 111-15
8. Thomson AM, West DC, Lodge D. An N-methylaspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine? Nature 1985; 313: 479-81
9. Shimaoka M, Iida T, Ohara A, et al. Ketamine inhibits nitric oxide production in mouse-activated macrophage-like cells. Br J Anaesth 1996; 77: 238-42
10. Li CY, Chou TC, Wong CS, et al. Ketamine inhibits nitric oxide synthase in lipopolysaccharide-treated rat alveolar macrophages. Can J Anaesth 1997; 44: 989-95
11. Galley HF, Webster NR. Brain nitric oxide synthase activity is decreased by intravenous anesthetics. Anesth Analg 1996; 83: 591-4
12. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coodinates, 2nd Edn. New York: Academic Press, 1986
13. Sato K, Wu J, Kikuchi T, Wang Y, Watanabe I, Okumura F. Differential effects of ketamine and pentobarbitone on acetylcholine release from the rat hippocampus and striatum. Br J Anaesth 1996; 77: 381-4
14. Ohta K, Araki N, Shibata M, et al. A novel assay system for consecutive measurement of brain nitric oxide production combined with the microdialysis technique. Neurosci Lett 1994; 176: 165-8
15. Yamada K, Nabeshima T. Simultaneous measurement of nitrite and nitrate levels as indices of nitric oxide release in the cerebellum of conscious rats. J Neurochem 1997; 68: 1234-43
16. Danhof M, Levy G. Kinetics of drug action in disease states. I. Effect of infusion rate on phenobarbital concentrations in serum, brain and cerebrospinal fluid of normal rats at onset of loss of righting reflex. J Pharmocol Exp Ther 1984; 229: 1-7
17. Tervo T, Jo F, Huikuri KT, Toth I, Palkama A. Fine structure of sensory nerves in the rat cornea: an experimental nerve degeneration study. Pain 1979; 6: 57-70
18. Gustafsson LL, Ebling WF, Osaki W, Stanski DR. Quantitation of depth of thiopental anesthesia in the rat. Anesthesiology 1996; 84: 415-27
19. Keane PE, Biziere K. The effects of general anesthetics on GABAergic synaptic transmission. Life Sci 1987; 41: 1437-48
20. Forstermann U, Gorsky LD, Pollock JS, Schmidt HH, Heller M, Murad F. Regional distribution of nitric oxide synthesizing enzyme(s) in rat brain. Biochem Biophysiol Res Commun 1990; 168: 727-32
21. Bennett MK, Drejer J, Schousboe A, Diemer NH. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 1984; 43: 1369-74
22. Schwieger IM, Szlam F, Hug CC jr. The pharmacokinetics of ketamine in dogs anesthetized with enflurane. J Pharmacokinet Biopharmacol 1991; 19: 145-56
23. Miyawaki I, Nakamura K, Yokubol B, Kitamura R, Mori K. Suppression of cyclic guanosine monophosphate formation in rat cerebellar slices by propofol, ketamine and midazolam. Can J Anaesth 1997; 44: 1301-7
24. Liu J, Moghaddam B. Regulation of glutamate efflux by excitatory amino acid receptors: evidence for tonic inhibitory and phasic excitatory regulation. J Pharmacol Exp Ther 1995; 274: 1209-15
25. Giovannini MG, Mutolo D, Bianchi L, Michelassi A, Pepeu G. NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study. J Neurosci 1994; 14:1358-65
26. Furchgott RF, Zawadski JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288: 373-6
27. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524-6
28. Smith DA, Hoffman AF, David DJ, Adams CE, Gerhardt GA. Nicotine-evoked nitric oxide release in the rat hippocampal slice. Neurosci Lett 1998; 255: 127-30
29. Bhardwaj A, Northington FJ, Ichord RI, Hanley DF, Traystman RJ, Koehler RC. Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats. Stroke 1997; 28: 851-7
30. Bhardwaj A, Northington FJ, Martin LJ, Hanley DF, Traystman RJ, Koehier RC. Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo. J Cereb Blood Flow Metab 1997; 17: 153-60
31. Smirnova T, Stinnakre J, Mallet J. Characterization of a presynaptic glutamate receptor. Science 1993; 262: 430-3
32. Adachi T, Kurata J, Nakao S, et al. Nitric oxide synthase inhibitor does not reduce minimum alveolar anesthetic concentration of halothane in rats. Anesth Analg 1994; 78: 1154-7
33. Tonner PH, Scholz J, Lamberz L, Schlamp N, Esch JS. Inhibition of nitric oxide synthase decreases anesthetic requirement of intravenous anesthetics in xenopus laevis. Anesthesiology 1997; 87:1479-85
34. Tobin JR, Martin LF, Breslow MJ, Traystman RJ. Selective anesthetic inhibition of brain nitric oxide synthase. Anesthesiology 1994; 81: 1264-9
35. Bannerman DM, Chapman PF, Kelly PAT, Butcher SP, Morris RGM. Inhibition of nitric oxide synthase does not prevent the induction of long-term potentiation in vivo. J Neurosci 1994; 14: 7415-25