Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells

Leukemia

Volumn 25, Issue 6, 2011, Pages 960-967

  Silva, A ^a   Girio A ^a   Cebola, I ^a   Santos, C I ^a   Antunes, F ^b   Barata, J T ^a,c  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b UNIVERSITY OF LISBON   (Portugal)

^c UNIVERSITY OF LISBON   (Portugal)

Author keywords

IL 7; signaling; T cell acute lymphoblastic leukemia

Indexed keywords

GLUCOSE TRANSPORTER 1; HYDROGEN PEROXIDE; INTERLEUKIN 7; MAMMALIAN TARGET OF RAPAMYCIN; PHLORETIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T CELL ACUTE LYMPHOBLASTIC LEUKEMIA; UPREGULATION;

CELL PROLIFERATION; CELL SURVIVAL; HUMANS; INTERLEUKIN-7; PHOSPHATIDYLINOSITOL 3-KINASES; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RECEPTOR CROSS-TALK; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 79958125269     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.56     Document Type: Article

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