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Volumn 300, Issue 6, 2011, Pages

Thiazolidinediones inhibit MDCK cyst growth through disrupting oriented cell division and apicobasal polarity

Author keywords

Cdc42; Lumen; PKD; Polarity; PPAR

Indexed keywords

CONTACTIN 1; PROTEIN CDC42; ROSIGLITAZONE; UVOMORULIN;

EID: 79958107431     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00482.2010     Document Type: Article
Times cited : (7)

References (35)
  • 1
    • 0035969248 scopus 로고    scopus 로고
    • Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud
    • Adamo JE, Moskow JJ, Gladfelter AS, Viterbo D, Lew DJ, Brennwald PJ. Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. J Cell Biol 155: 581-592, 2001.
    • (2001) J Cell Biol , vol.155 , pp. 581-592
    • Adamo, J.E.1    Moskow, J.J.2    Gladfelter, A.S.3    Viterbo, D.4    Lew, D.J.5    Brennwald, P.J.6
  • 3
    • 70350787220 scopus 로고    scopus 로고
    • Polarity is destiny
    • Cai L, Mostov K. Polarity is destiny. Cell 139: 660-662, 2009.
    • (2009) Cell , vol.139 , pp. 660-662
    • Cai, L.1    Mostov, K.2
  • 4
    • 21644460380 scopus 로고    scopus 로고
    • Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways
    • Cau J, Hall A. Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways. J Cell Sci 118: 2579-2587, 2005.
    • (2005) J Cell Sci , vol.118 , pp. 2579-2587
    • Cau, J.1    Hall, A.2
  • 5
    • 39149104042 scopus 로고    scopus 로고
    • Autosomal dominant polycystic kidney disease: Recent advances in pathogenesis and treatment
    • Chang MY, Ong AC. Autosomal dominant polycystic kidney disease: recent advances in pathogenesis and treatment. Nephron Physiol 108: p1-p7, 2008.
    • (2008) Nephron Physiol , vol.108
    • Chang, M.Y.1    Ong, A.C.2
  • 6
    • 77956391365 scopus 로고    scopus 로고
    • Rosiglitazone attenuates development of polycystic kidney disease and prolongs survival in Han:SPRD rats
    • Dai B, Liu Y, Mei C, Fu L, Xiong X, Zhang Y, Shen X, Hua Z. Rosiglitazone attenuates development of polycystic kidney disease and prolongs survival in Han:SPRD rats. Clin Sci (Lond) 119: 323-333, 2010.
    • (2010) Clin Sci (Lond) , vol.119 , pp. 323-333
    • Dai, B.1    Liu, Y.2    Mei, C.3    Fu, L.4    Xiong, X.5    Zhang, Y.6    Shen, X.7    Hua, Z.8
  • 7
    • 68149181683 scopus 로고    scopus 로고
    • The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42
    • Das M, Wiley DJ, Chen X, Shah K, Verde F. The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42. Curr Biol 19: 1314-1319, 2009.
    • (2009) Curr Biol , vol.19 , pp. 1314-1319
    • Das, M.1    Wiley, D.J.2    Chen, X.3    Shah, K.4    Verde, F.5
  • 9
    • 0034595381 scopus 로고    scopus 로고
    • Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK
    • del Pozo MA, Price LS, Alderson NB, Ren XD, Schwartz MA. Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK. EMBO J 19: 2008-2014, 2000.
    • (2000) EMBO J , vol.19 , pp. 2008-2014
    • del Pozo, M.A.1    Price, L.S.2    Alderson, N.B.3    Ren, X.D.4    Schwartz, M.A.5
  • 10
    • 69949106214 scopus 로고    scopus 로고
    • Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia
    • den Elzen N, Buttery CV, Maddugoda MP, Ren G, Yap AS. Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia. Mol Biol Cell 20: 3740-3750, 2009.
    • (2009) Mol Biol Cell , vol.20 , pp. 3740-3750
    • den Elzen, N.1    Buttery, C.V.2    Maddugoda, M.P.3    Ren, G.4    Yap, A.S.5
  • 11
    • 2342432240 scopus 로고    scopus 로고
    • Cdc42-the centre of polarity
    • Etienne-Manneville S. Cdc42-the centre of polarity. J Cell Sci 117: 1291-1300, 2004.
    • (2004) J Cell Sci , vol.117 , pp. 1291-1300
    • Etienne-Manneville, S.1
  • 12
    • 58149191544 scopus 로고    scopus 로고
    • Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
    • Jaffe AB, Kaji N, Durgan J, Hall A. Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J Cell Biol 183: 625-633, 2008.
    • (2008) J Cell Biol , vol.183 , pp. 625-633
    • Jaffe, A.B.1    Kaji, N.2    Durgan, J.3    Hall, A.4
  • 13
    • 26444468152 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells
    • Johnson FM, Saigal B, Talpaz M, Donato NJ. Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells. Clin Cancer Res 11: 6924-6932, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 6924-6932
    • Johnson, F.M.1    Saigal, B.2    Talpaz, M.3    Donato, N.J.4
  • 15
    • 0034711219 scopus 로고    scopus 로고
    • E-cadherin-mediated cell-cell attachment activates Cdc42
    • Kim SH, Li Z, Sacks DB. E-cadherin-mediated cell-cell attachment activates Cdc42. J Biol Chem 275: 36999-37005, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 36999-37005
    • Kim, S.H.1    Li, Z.2    Sacks, D.B.3
  • 17
    • 67449152144 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists in kidney disease-future promise, present fears
    • Mao Z, Ong AC. Peroxisome proliferator-activated receptor gamma agonists in kidney disease-future promise, present fears. Nephron Clin Pract 112: c230-c241, 2009.
    • (2009) Nephron Clin Pract , vol.112
    • Mao, Z.1    Ong, A.C.2
  • 18
    • 33846270032 scopus 로고    scopus 로고
    • PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42
    • Martin-Belmonte F, Gassama A, Datta A, Yu W, Rescher U, Gerke V, Mostov K. PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell 128: 383-397, 2007.
    • (2007) Cell , vol.128 , pp. 383-397
    • Martin-Belmonte, F.1    Gassama, A.2    Datta, A.3    Yu, W.4    Rescher, U.5    Gerke, V.6    Mostov, K.7
  • 20
    • 0035341316 scopus 로고    scopus 로고
    • cdc42 regulates the exit of apical and basolateral proteins from the trans-Golgi network
    • Musch A, Cohen D, Kreitzer G, Rodriguez-Boulan E. cdc42 regulates the exit of apical and basolateral proteins from the trans-Golgi network. EMBO J 20: 2171-2179, 2001.
    • (2001) EMBO J , vol.20 , pp. 2171-2179
    • Musch, A.1    Cohen, D.2    Kreitzer, G.3    Rodriguez-Boulan, E.4
  • 22
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes CD, Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81: 53-62, 1995.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 23
    • 16244414299 scopus 로고    scopus 로고
    • Molecular pathogenesis of ADPKD: The polycystin complex gets complex
    • Ong AC, Harris PC. Molecular pathogenesis of ADPKD: the polycystin complex gets complex. Kidney Int 67: 1234-1247, 2005.
    • (2005) Kidney Int , vol.67 , pp. 1234-1247
    • Ong, A.C.1    Harris, P.C.2
  • 24
    • 0032387652 scopus 로고    scopus 로고
    • Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis
    • Pollack AL, Runyan RB, Mostov KE. Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis. Dev Biol 204: 64-79, 1998.
    • (1998) Dev Biol , vol.204 , pp. 64-79
    • Pollack, A.L.1    Runyan, R.B.2    Mostov, K.E.3
  • 26
    • 34548291544 scopus 로고    scopus 로고
    • Spatial regulation of Cdc42 during cytokinesis
    • Rincon S, Coll PM, Perez P. Spatial regulation of Cdc42 during cytokinesis. Cell Cycle 6: 1687-1691, 2007.
    • (2007) Cell Cycle , vol.6 , pp. 1687-1691
    • Rincon, S.1    Coll, P.M.2    Perez, P.3
  • 27
    • 0242585394 scopus 로고    scopus 로고
    • The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis
    • Rogers KK, Jou TS, Guo W, Lipschutz JH. The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis. Kidney Int 63: 1632-1644, 2003.
    • (2003) Kidney Int , vol.63 , pp. 1632-1644
    • Rogers, K.K.1    Jou, T.S.2    Guo, W.3    Lipschutz, J.H.4
  • 28
    • 0030947354 scopus 로고    scopus 로고
    • An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors
    • Sakurai H, Barros EJ, Tsukamoto T, Barasch J, Nigam SK. An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors. Proc Natl Acad Sci USA 94: 6279-6284, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6279-6284
    • Sakurai, H.1    Barros, E.J.2    Tsukamoto, T.3    Barasch, J.4    Nigam, S.K.5
  • 29
    • 34547604466 scopus 로고    scopus 로고
    • Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity
    • Schlessinger K, McManus EJ, Hall A. Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity. J Cell Biol 178: 355-361, 2007.
    • (2007) J Cell Biol , vol.178 , pp. 355-361
    • Schlessinger, K.1    McManus, E.J.2    Hall, A.3
  • 30
    • 78649637949 scopus 로고    scopus 로고
    • Protein kinase D mediated phosphorylation of polycystin-2 (TRPP2) is essential for its effects on cell growth and calcium channel activity
    • Streets AJ, Needham AJ, Gill SK, Ong AC. Protein kinase D mediated phosphorylation of polycystin-2 (TRPP2) is essential for its effects on cell growth and calcium channel activity. Mol Biol Cell 21: 3853-3865, 2010.
    • (2010) Mol Biol Cell , vol.21 , pp. 3853-3865
    • Streets, A.J.1    Needham, A.J.2    Gill, S.K.3    Ong, A.C.4
  • 31
    • 44449156338 scopus 로고    scopus 로고
    • Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis
    • Torkko JM, Manninen A, Schuck S, Simons K. Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis. J Cell Sci 121: 1193-1203, 2008.
    • (2008) J Cell Sci , vol.121 , pp. 1193-1203
    • Torkko, J.M.1    Manninen, A.2    Schuck, S.3    Simons, K.4
  • 32
    • 33846224660 scopus 로고    scopus 로고
    • Antagonism of endogenous putative P2Y receptors reduces the growth of MDCK-derived cysts cultured in vitro
    • Turner CM, King BF, Srai KS, Unwin RJ. Antagonism of endogenous putative P2Y receptors reduces the growth of MDCK-derived cysts cultured in vitro. Am J Physiol Renal Physiol 292: F15-F25, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Turner, C.M.1    King, B.F.2    Srai, K.S.3    Unwin, R.J.4
  • 33
    • 0031970799 scopus 로고    scopus 로고
    • Apoptosis and necrosis during ischaemia in renal tubular cells (LLC-PK1 and MDCK)
    • Wiegele G, Brandis M, Zimmerhackl LB. Apoptosis and necrosis during ischaemia in renal tubular cells (LLC-PK1 and MDCK). Nephrol Dial Transplant 13: 1158-1167, 1998.
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 1158-1167
    • Wiegele, G.1    Brandis, M.2    Zimmerhackl, L.B.3
  • 34
    • 0030773047 scopus 로고    scopus 로고
    • Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. comparison of kinetic properties of cdc42 binding to the cdc42-interactive domains
    • Zhang B, Wang ZX, Zheng Y. Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. comparison of kinetic properties of cdc42 binding to the cdc42-interactive domains. J Biol Chem 272: 21999-22007, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 21999-22007
    • Zhang, B.1    Wang, Z.X.2    Zheng, Y.3
  • 35
    • 38849204971 scopus 로고    scopus 로고
    • The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity
    • Zhang S, Schafer-Hales K, Khuri FR, Zhou W, Vertino PM, Marcus AI. The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Res 68: 740-748, 2008.
    • (2008) Cancer Res , vol.68 , pp. 740-748
    • Zhang, S.1    Schafer-Hales, K.2    Khuri, F.R.3    Zhou, W.4    Vertino, P.M.5    Marcus, A.I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.