German national case collection for familial pancreatic cancer (FaPaCa): Ten years experience

Familial Cancer

Volumn 10, Issue 2, 2011, Pages 323-330

  Schneider, Ralph ^a   Slater, Emily P ^a   Sina, Mercede ^a   Habbe, Nils ^a   Fendrich, Volker ^a   Matthäi, Elvira ^a   Langer, Peter ^a   Bartsch, Detlef K ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Familial pancreatic cancer; Genetic susceptibility; Hereditary tumor syndrome; Screening

Indexed keywords

BRCA2 PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 2A; PALB2 PROTEIN; PALLD PROTEIN; PROTEIN KINASE LKB1; RNASEL PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BREAST CANCER; CANCER DIAGNOSIS; CANCER REGISTRY; CANCER RISK; CANCER SUSCEPTIBILITY; CHOLANGIOGRAPHY; COLON CANCER; COLORECTAL CANCER; COMORBIDITY; CONTROLLED STUDY; ENDOSCOPIC ECHOGRAPHY; FAMILIAL CANCER; FAMILIAL PANCREATIC CANCER; FEMALE; GENE DELETION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC COUNSELING; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GERM LINE; GERMANY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG CANCER; MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAHY; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PANCREAS CANCER; PEDIGREE ANALYSIS; PRECANCER; PRIORITY JOURNAL; PROGENY; PROSTATE CANCER;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; GENES, BRCA2; GERMANY; HUMANS; MALE; MIDDLE AGED; MUTATION; NUCLEAR PROTEINS; PANCREATIC NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 79958100278     PISSN: 13899600     EISSN: 15737292     Source Type: Journal    
DOI: 10.1007/s10689-010-9414-x     Document Type: Article

References (39)

1. AM Cooperman 2001 Pancreatic cancer: the bigger picture Surg Clin North Am 81 557 574 11459271 10.1016/S0039-6109(05)70143-2 1:STN:280: DC%2BD3MvgslyisQ%3D%3D (Pubitemid 32612116)
2. SP Cleary R Gryfe M Guindi, et al. 2004 Prognostic factors in resected pancreatic adenocarcinoma: analysis of actual 5-year survivors J Am Coll Surg 198 722 731 15110805 10.1016/j.jamcollsurg.2004.01.008 (Pubitemid 38542900)
3. RH Hruban GM Petersen PK Ha, et al. 1998 Genetics of pancreatic cancer. From genes to families Surg Oncol Clin N Am 7 1 23 9443984 1:STN:280: DyaK1c7gvVSmsA%3D%3D (Pubitemid 28108790)
4. HT Lynch RE Brand CA Deters, et al. 2001 Hereditary pancreatic cancer Pancreatology 1 466 471 12120226 10.1159/000055849 1:CAS:528: DC%2BD3MXnsVemu7w%3D (Pubitemid 33681749)
5. SE Applebaum JA Kant DC Whitcomb, et al. 2000 Genetic testing. Counseling, laboratory, and regulatory issues and the EUROPAC protocol for ethical research in multicenter studies of inherited pancreatic diseases Med Clin North Am 84 575 588 10872415 10.1016/S0025-7125(05)70241-8 1:STN:280:DC%2BD3czjtFaiuw%3D%3D viii (Pubitemid 30346153)
6. D Ehrenthal L Haeger T Griffin, et al. 1987 Familial pancreatic adenocarcinoma in three generations. A case report and a review of the literature Cancer 59 1661 1664 3828965 10.1002/1097-0142(19870501)59:9<1661:: AID-CNCR2820590923>3.0.CO;2-H 1:STN:280:DyaL2s7lvFWrsQ%3D%3D (Pubitemid 17060113)
7. RP MacDermott P Kramer 1973 Adenocarcinoma of the pancreas in four siblings Gastroenterology 65 137 139 4720820 1:STN:280:DyaE3s3isFWrtQ%3D%3D
8. RR Reimer JF Fraumeni Jr RF Ozols, et al. 1977 Pancreatic cancer in father and son Lancet 1 911 67325 10.1016/S0140-6736(77)91244-2 1:STN:280:DyaE2s7mvFyhsA%3D%3D
9. HT Lynch SJ Lanspa RJ Fitzgibbons Jr, et al. 1989 Familial pancreatic cancer (part 1): genetic pathology review Nebr Med J 74 109 112 2542813 1:STN:280:DyaL1M3mt1eiuw%3D%3D
10. DK Bartsch M Sina-Frey A Ziegler, et al. 2001 Update of familial pancreatic cancer in Germany Pancreatology 1 510 516 12120230 10.1159/000055853 1:CAS:528:DC%2BD3MXnsVemu7c%3D (Pubitemid 33681753)
11. AC Tersmette GM Petersen GJ Offerhaus, et al. 2001 Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer Clin Cancer Res 7 738 744 11297271 1:STN:280:DC%2BD3Mrks1Kktg%3D%3D (Pubitemid 32708001)
12. RH Hruban GM Petersen M Goggins, et al. 1999 Familial pancreatic cancer Ann Oncol 10 Suppl 4 69 73 10436789 10.1023/A:1008345021197
13. DK Bartsch R Kress M Sina-Frey, et al. 2004 Prevalence of familial pancreatic cancer in Germany Int J Cancer 110 902 906 15170674 10.1002/ijc.20210 1:CAS:528:DC%2BD2cXkvFCmtL0%3D (Pubitemid 38758518)
14. K Hemminki X Li 2003 Familial and second primary pancreatic cancers: a nationwide epidemiologic study from Sweden Int J Cancer 103 525 530 12478670 10.1002/ijc.10863 1:CAS:528:DC%2BD3sXhvVOiug%3D%3D (Pubitemid 36020229)
15. SA Hahn B Greenhalf I Ellis, et al. 2003 BRCA2 germline mutations in familial pancreatic carcinoma J Natl Cancer Inst 95 214 221 12569143 10.1093/jnci/95.3.214 1:CAS:528:DC%2BD3sXit1emsL0%3D (Pubitemid 36240634)
16. DK Bartsch V Fendrich EP Slater, et al. 2005 RNASEL germline variants are associated with pancreatic cancer Int J Cancer 117 718 722 15981205 10.1002/ijc.21254 1:CAS:528:DC%2BD2MXht1ShsbnL (Pubitemid 41598821)
17. DK Bartsch K Krysewski M Sina-Frey, et al. 2006 Low frequency of CHEK2 mutations in familial pancreatic cancer Fam Cancer 5 305 308 16858628 10.1007/s10689-006-7850-4 1:CAS:528:DC%2BD28Xht1yktbjP (Pubitemid 44924105)
18. DK Bartsch M Sina-Frey S Lang, et al. 2002 CDKN2A germline mutations in familial pancreatic cancer Ann Surg 236 730 737 12454511 10.1097/00000658- 200212000-00005 (Pubitemid 35403228)
19. R Grutzmann C McFaul DK Bartsch, et al. 2004 No evidence for germline mutations of the LKB1/STK11 gene in familial pancreatic carcinoma Cancer Lett 214 63 68 15331174 10.1016/j.canlet.2004.06.012 (Pubitemid 39141199)
20. K Nej DK Bartsch M Sina-Frey, et al. 2004 The NOD23020insC mutation and the risk of familial pancreatic cancer? Hered Cancer Clin Pract 2 149 150 20233470 10.1186/1897-4287-2-3-149
21. E Slater V Amrillaeva V Fendrich, et al. 2007 Palladin mutation causes familial pancreatic cancer: absence in European families PLoS Med 4 e164 17455999 10.1371/journal.pmed.0040164 (Pubitemid 46658784)
22. Slater EP, Langer P, Habbe N et al. (2010) Prevalence of PALB2 mutations in familial pancreatic cancer. Clin Genet (in press)
23. Dk Bartsch P Langer N Habbe, et al. 2009 Clinical and genetic analysis of 18 pancreatic carcinoma/melanoma-prone families Clin Genet 77 333 341 20041885 10.1111/j.1399-0004.2009.01352.x
24. CD McFaul W Greenhalf J Earl, et al. 2006 Anticipation in familial pancreatic cancer Gut 55 252 258 15972300 10.1136/gut.2005.065045 1:STN:280:DC%2BD28%2FitVSltQ%3D%3D (Pubitemid 43117286)
25. EP Slater P Langer V Fendrich, et al. 2010 Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families Fam Cancer 9 335 343 20195775 10.1007/s10689-010-9329-6 1:CAS:528:DC%2BC3cXhtVahtL%2FE
26. P Langer PH Kann V Fendrich, et al. 2009 Five years of prospective screening of high-risk individuals from families with familial pancreatic cancer Gut 58 1410 1418 19470496 10.1136/gut.2008.171611 1:STN:280: DC%2BD1Mnhs12ntQ%3D%3D
27. HT Lynch L Fusaro TC Smyrk, et al. 1995 Medical genetic study of eight pancreatic cancer-prone families Cancer Invest 13 141 149 7874567 10.3109/07357909509011683 1:STN:280:DyaK2M7nvFKisQ%3D%3D
28. W Greenhalf N Malats M Nilsson, et al. 2008 International registries of families at high risk of pancreatic cancer Pancreatology 8 558 565 18818508 10.1159/000159214
29. J Schuz D Schon W Batzler, et al. 2000 Cancer registration in Germany: current status, perspectives and trends in cancer incidence 1973-93 J Epidemiol Biostat 5 99 107 10890281 1:STN:280:DC%2BD3M%2FjtVOktw%3D%3D
30. KM Murphy KA Brune C Griffin, et al. 2002 Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17% Cancer Res 62 3789 3793 12097290 1:CAS:528: DC%2BD38XltF2jur0%3D (Pubitemid 34728862)
31. FJ Couch MR Johnson KG Rabe, et al. 2007 The prevalence of BRCA2 mutations in familial pancreatic cancer Cancer Epidemiol Biomark Prev 16 342 346 10.1158/1055-9965.EPI-06-0783 1:CAS:528:DC%2BD2sXhs1ylsLY%3D (Pubitemid 46383356)
32. S Jones RH Hruban M Kamiyama, et al. 2009 Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene Science 324 217 19264984 10.1126/science.1171202 1:CAS:528:DC%2BD1MXktFalsr0%3D
33. KL Pogue-Geile R Chen MP Bronner, et al. 2006 Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism PLoS Med 3 e516 17194196 10.1371/journal.pmed.0030516 (Pubitemid 46026443)
34. J Earl L Yan LJ Vitone, et al. 2006 Evaluation of the 4q32-34 locus in European familial pancreatic cancer Cancer Epidemiol Biomark Prev 15 1948 1955 10.1158/1055-9965.EPI-06-0376 1:CAS:528:DC%2BD28XhtVGktbnE (Pubitemid 44664273)
35. RE Brand 2009 Screening for familial pancreatic cancer: is doing something better than doing nothing? Gut 58 1321 1322 19749135 10.1136/gut.2009.181214
36. MI Canto M Goggins CJ Yeo, et al. 2004 Screening for pancreatic neoplasia in high-risk individuals: an EUS-based approach Clin Gastroenterol Hepatol 2 606 621 15224285 10.1016/S1542-3565(04)00244-7 (Pubitemid 38834045)
37. MI Canto M Goggins RH Hruban, et al. 2006 Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study Clin Gastroenterol Hepatol 4 766 781 16682259 10.1016/j.cgh.2006.02.005 (Pubitemid 43825802)
38. JW Poley I Kluijt DJ Gouma, et al. 2009 The yield of first-time endoscopic ultrasonography in screening individuals at a high risk of developing pancreatic cancer Am J Gastroenterol 104 2175 2181 19491823 10.1038/ajg.2009.276 1:STN:280:DC%2BD1MrpvVKmsw%3D%3D
39. TA Brentnall 2005 Management strategies for patients with hereditary pancreatic cancer Curr Treat Options Oncol 6 437 445 16107246 10.1007/s11864-005-0046-6 (Pubitemid 41684223)