-
2
-
-
0034043609
-
Genetic testing. Counseling, laboratory, and regulatory issues and the EUROPAC protocol for ethical research in multicenter studies of inherited pancreatic diseases
-
Applebaum SE, Kant JA, Whitcomb DC et al (2000) Genetic testing. Counseling, laboratory, and regulatory issues and the EUROPAC protocol for ethical research in multicenter studies of inherited pancreatic diseases. Med Clin North Am 84:575-588
-
(2000)
Med. Clin. North Am.
, vol.84
, pp. 575-588
-
-
Applebaum, S.E.1
Kant, J.A.2
Whitcomb, D.C.3
-
3
-
-
0035552527
-
Update of familial pancreatic cancer in Germany
-
Bartsch DK, Sina-Frey M, Ziegler A et al (2001) Update of familial pancreatic cancer in Germany. Pancreatology 1:510-516
-
(2001)
Pancreatology
, vol.1
, pp. 510-516
-
-
Bartsch, D.K.1
Sina-Frey, M.2
Ziegler, A.3
-
4
-
-
11144353646
-
Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds
-
Klein AP, Brune KA, Petersen GM et al (2004) Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res 64:2634-2638
-
(2004)
Cancer Res.
, vol.64
, pp. 2634-2638
-
-
Klein, A.P.1
Brune, K.A.2
Petersen, G.M.3
-
5
-
-
30944451530
-
Anticipation in familial pancreatic cancer
-
McFaul CD, Greenhalf W, Earl J et al (2005) Anticipation in familial pancreatic cancer. Gut 55:252-258
-
(2005)
Gut
, vol.55
, pp. 252-258
-
-
McFaul, C.D.1
Greenhalf, W.2
Earl, J.3
-
7
-
-
0036644884
-
Evaluation of candidate genes MAP2K4, MADH4, ACVR1B and BRCA2 in familial pancreatic cancer: Deleterious BRCA2 mutations in 17%
-
Murphy KM, Brune KA, Griffin C et al (2002) Evaluation of candidate genes MAP2K4, MADH4, ACVR1B and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. Cancer Res 62:3789-3793
-
(2002)
Cancer Res.
, vol.62
, pp. 3789-3793
-
-
Murphy, K.M.1
Brune, K.A.2
Griffin, C.3
-
8
-
-
4344617965
-
No evidence for germline mutations of the LKB1/STK11 gene in familial pancreatic carcinoma
-
Grützmann R, McFaul CD, Bartsch DK et al (2004) No evidence for germline mutations of the LKB1/STK11 gene in familial pancreatic carcinoma. Cancer Lett 214:63-68
-
(2004)
Cancer Lett.
, vol.214
, pp. 63-68
-
-
Grützmann, R.1
McFaul, C.D.2
Bartsch, D.K.3
-
9
-
-
27744598757
-
RNASEL germline variants are associated with pancreatic cancer
-
Bartsch D, Fendrich V, Slater E et al (2005) RNASEL germline variants are associated with pancreatic cancer. Int J Cancer 117:718-722
-
(2005)
Int. J. Cancer
, vol.117
, pp. 718-722
-
-
Bartsch, D.1
Fendrich, V.2
Slater, E.3
-
10
-
-
33845548766
-
Low frequency of CHEK2 mutations in familial pancreatic cancer
-
Bartsch DK, Krysewski K, Sina-Frey M et al (2006) Low frequency of CHEK2 mutations in familial pancreatic cancer. Fam Cancer 5(4):305-308
-
(2006)
Fam Cancer
, vol.5
, Issue.4
, pp. 305-308
-
-
Bartsch, D.K.1
Krysewski, K.2
Sina-Frey, M.3
-
11
-
-
0036895738
-
CDKN2A germline mutations in familial pancreatic cancer
-
Bartsch D, Sina-Frey M, Lang S et al (2002) CDKN2A germline mutations in familial pancreatic cancer. Ann Surg 236:730-737
-
(2002)
Ann. Surg.
, vol.236
, pp. 730-737
-
-
Bartsch, D.1
Sina-Frey, M.2
Lang, S.3
-
12
-
-
0036143702
-
Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: The familial atypical mole melanoma-pancreatic carcinoma syndrome
-
Lynch H, Brand R, Hogg D et al (2002) Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome. Cancer 94:84-96
-
(2002)
Cancer
, vol.94
, pp. 84-96
-
-
Lynch, H.1
Brand, R.2
Hogg, D.3
-
13
-
-
0029041032
-
Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region
-
Schutte M, da Costa LT, Hahn SA et al (1995) Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region. Proc Natl Acad Sci USA 92:5950-5954
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5950-5954
-
-
Schutte, M.1
Da Costa, L.T.2
Hahn, S.A.3
-
14
-
-
0033523268
-
Cancer risks in BRCA2 mutation carriers
-
Breast Cancer Linkage Consortium
-
Breast Cancer Linkage Consortium (1999) Cancer risks in BRCA2 mutation carriers. J Natl Cancer Inst 91:1310-1316
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1310-1316
-
-
-
15
-
-
0034125368
-
Association of the I1307 K APC mutation with hereditary and sporadic breast/ovarian cancer: More questions than answers
-
Gershoni-Baruch R, Patael Y, Dagan et al (2000) Association of the I1307 K APC mutation with hereditary and sporadic breast/ovarian cancer: more questions than answers. Br J Cancer 83:153-155
-
(2000)
Br. J. Cancer
, vol.83
, pp. 153-155
-
-
Gershoni-Baruch, R.1
Patael, Y.2
Dagan3
-
16
-
-
12644253827
-
Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas
-
Goggins M, Schutte M, Lu J et al (1996) Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res 56:5360-5364
-
(1996)
Cancer Res.
, vol.56
, pp. 5360-5364
-
-
Goggins, M.1
Schutte, M.2
Lu, J.3
-
17
-
-
0031137173
-
Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients
-
Ozçelik H, Schmocker B, Di Nicola N et al (1997) Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients. Nat Genet 16:17-18
-
(1997)
Nat. Genet.
, vol.16
, pp. 17-18
-
-
Ozçelik, H.1
Schmocker, B.2
Di Nicola, N.3
-
18
-
-
0037420026
-
BRCA2 germline mutations in familial pancreatic carcinoma
-
Hahn SA, Greenhalf W, Ellis I et al (2003) BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst 95:214-221
-
(2003)
J. Natl. Cancer Inst.
, vol.95
, pp. 214-221
-
-
Hahn, S.A.1
Greenhalf, W.2
Ellis, I.3
-
19
-
-
19944414645
-
Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer
-
Martin ST, Matsubayashi H, Rogers CD et al (2005) Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer. Oncogene 24:3652-3656
-
(2005)
Oncogene
, vol.24
, pp. 3652-3656
-
-
Martin, S.T.1
Matsubayashi, H.2
Rogers, C.D.3
-
21
-
-
0036269812
-
Familial pancreatic cancer-concept for study of the National Case Collection and early diagnosis program for high risk people
-
Gerdes B, Kress R, Rieder H et al (2002) Familial pancreatic cancer-concept for study of the National Case Collection and early diagnosis program for high risk people. Z Arztl Fortbild Qualitatssich 96:251-255
-
(2002)
Z Arztl Fortbild Qualitatssich
, vol.96
, pp. 251-255
-
-
Gerdes, B.1
Kress, R.2
Rieder, H.3
-
22
-
-
0035996222
-
German national case collection of familial pancreatic cancer-clinical-genetic analysis of the first 21 families
-
Rieder H, Sina-Frey M, Ziegler A et al (2002) German national case collection of familial pancreatic cancer-clinical-genetic analysis of the first 21 families. Onkologie 25:262-266
-
(2002)
Onkologie
, vol.25
, pp. 262-266
-
-
Rieder, H.1
Sina-Frey, M.2
Ziegler, A.3
-
23
-
-
34948870763
-
Advances in counselling and surveillance of patients at risk for pancreatic cancer
-
Brand RE, Lerch MM, Rubinstein WS et al (2007) Advances in counselling and surveillance of patients at risk for pancreatic cancer. Gut 56:1460-1469
-
(2007)
Gut
, vol.56
, pp. 1460-1469
-
-
Brand, R.E.1
Lerch, M.M.2
Rubinstein, W.S.3
-
24
-
-
0033572622
-
Denaturing high-performance liquid chromatography detects reliably BRCA1 and BRCA2 mutations
-
Wagner T, Stoppa-Lyonnet D, Fleischmann E et al (1999) Denaturing high-performance liquid chromatography detects reliably BRCA1 and BRCA2 mutations. Genomics 62:369-376
-
(1999)
Genomics
, vol.62
, pp. 369-376
-
-
Wagner, T.1
Stoppa-Lyonnet, D.2
Fleischmann, E.3
-
25
-
-
46049106796
-
Hereditary diffuse gastric cancer
-
Lynch HT, Kaurah P, Wirtzfeld D et al (2008) Hereditary diffuse gastric cancer. Cancer 112:2655-2663
-
(2008)
Cancer
, vol.112
, pp. 2655-2663
-
-
Lynch, H.T.1
Kaurah, P.2
Wirtzfeld, D.3
-
26
-
-
70349318044
-
5 Years of prospective screening of high risk individuals from familial pancreatic cancer families
-
Langer P, Kann PH, Fendrich V et al (2009) 5 Years of prospective screening of high risk individuals from familial pancreatic cancer families. Gut 58:1410-1418
-
(2009)
Gut
, vol.58
, pp. 1410-1418
-
-
Langer, P.1
Kann, P.H.2
Fendrich, V.3
-
27
-
-
1242272911
-
Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer
-
Hu N, Wang C, Han XY et al (2004) Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer. Oncogene 23:852-858
-
(2004)
Oncogene
, vol.23
, pp. 852-858
-
-
Hu, N.1
Wang, C.2
Han, X.Y.3
-
28
-
-
0034596343
-
High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families
-
Borg A, Sandberg T, Nilsson K et al (2000) High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families. J Natl Cancer Inst 92:1260-1266
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1260-1266
-
-
Borg, A.1
Sandberg, T.2
Nilsson, K.3
-
29
-
-
0029129816
-
Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations
-
Goldstein A, Fraser M, Struewing J et al (1995) Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations. N Engl J Med 333:970-974
-
(1995)
N Engl. J. Med.
, vol.333
, pp. 970-974
-
-
Goldstein, A.1
Fraser, M.2
Struewing, J.3
-
30
-
-
0043073213
-
Characterization of the neoplastic phenotype in the familial atypical multiple-mole melanoma-pancreatic carcinoma syndrome
-
Rulyak S, Brentnall T, Lynch H et al (2003) Characterization of the neoplastic phenotype in the familial atypical multiple-mole melanoma-pancreatic carcinoma syndrome. Cancer 98:798-804
-
(2003)
Cancer
, vol.98
, pp. 798-804
-
-
Rulyak, S.1
Brentnall, T.2
Lynch, H.3
-
31
-
-
0033836334
-
Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden)
-
Vasen H, Gruis N, Frants R et al (2000) Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). Int J Cancer 87:809-811
-
(2000)
Int. J. Cancer
, vol.87
, pp. 809-811
-
-
Vasen, H.1
Gruis, N.2
Frants, R.3
-
32
-
-
14444284330
-
Tumor-suppressive pathways in pancreatic carcinoma
-
Rozenblum E, Schutte M, Goggins M et al (1997) Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res 57:1731-1734
-
(1997)
Cancer Res.
, vol.57
, pp. 1731-1734
-
-
Rozenblum, E.1
Schutte, M.2
Goggins, M.3
-
33
-
-
0034650411
-
Inherited predisposition to pancreatic adenocarcinoma: Role of family history and germline p16, BRCA1, and BRCA2 mutations
-
Lal G, Liu G, Schmocker B et al (2000) Inherited predisposition to pancreatic adenocarcinoma: role of family history and germline p16, BRCA1, and BRCA2 mutations. Cancer Res 60:409-416
-
(2000)
Cancer Res.
, vol.60
, pp. 409-416
-
-
Lal, G.1
Liu, G.2
Schmocker, B.3
-
34
-
-
0030025518
-
Compilation of somatic mutations of the CDKN2 gene in human cancers: Nonrandom distribution of base substitutions
-
Pollock PM, Pearson JV, Hayward NK (1996) Compilation of somatic mutations of the CDKN2 gene in human cancers: nonrandom distribution of base substitutions. Genes Chromosomes Cancer 15:77-88
-
(1996)
Genes Chromosomes Cancer
, vol.15
, pp. 77-88
-
-
Pollock, P.M.1
Pearson, J.V.2
Hayward, N.K.3
-
35
-
-
0028998866
-
Mutations associated with familial melanoma impair p16INK4 function
-
Ranade K, Hussussian CJ, Sikorski RS et al (1995) Mutations associated with familial melanoma impair p16INK4 function. Nat Genet 10:114-116
-
(1995)
Nat. Genet.
, vol.10
, pp. 114-116
-
-
Ranade, K.1
Hussussian, C.J.2
Sikorski, R.S.3
-
36
-
-
35748952836
-
Differences in the frequency and distribution of BRCA1 and BRCA2 mutations in breast/ovarian cancer cases from the Basque country with respect to the Spanish population: Implications for genetic counselling
-
Beristain E, Martíneuz-Bouzas C, Guerra I et al (2007) Differences in the frequency and distribution of BRCA1 and BRCA2 mutations in breast/ovarian cancer cases from the Basque country with respect to the Spanish population: implications for genetic counselling. Breast Cancer Res Treat 106:255-262
-
(2007)
Breast Cancer Res. Treat.
, vol.106
, pp. 255-262
-
-
Beristain, E.1
Martíneuz-Bouzas, C.2
Guerra, I.3
-
37
-
-
0031950026
-
Recent discoveries in cancer genetics of exocrine pancreatic neoplasia
-
Hahn SA, Schmiegel WH (1998) Recent discoveries in cancer genetics of exocrine pancreatic neoplasia. Digestion 59:493-501
-
(1998)
Digestion
, vol.59
, pp. 493-501
-
-
Hahn, S.A.1
Schmiegel, W.H.2
-
38
-
-
0034463357
-
Genetic counseling and testing for germline p16 mutations in two pancreatic cancerprone families
-
Lynch HT, Brand RE, Lynch JF et al (2000) Genetic counseling and testing for germline p16 mutations in two pancreatic cancerprone families. Gastroenterology 119:1756-1760
-
(2000)
Gastroenterology
, vol.119
, pp. 1756-1760
-
-
Lynch, H.T.1
Brand, R.E.2
Lynch, J.F.3
-
39
-
-
0036466858
-
Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population
-
German Consortium for Hereditary Breast and Ovarian Cancer
-
German Consortium for Hereditary Breast and Ovarian Cancer (2002) Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population. Int J Cancer 97:472-480
-
(2002)
Int. J. Cancer
, vol.97
, pp. 472-480
-
-
-
40
-
-
0033578479
-
Early diagnosis and treatment of pancreatic dysplasia in patients with a family history of pancreatic cancer
-
Brentnall TA, Bronner MP, Byrd DR et al (1999) Early diagnosis and treatment of pancreatic dysplasia in patients with a family history of pancreatic cancer. Ann Intern Med 131:247-255
-
(1999)
Ann. Intern. Med.
, vol.131
, pp. 247-255
-
-
Brentnall, T.A.1
Bronner, M.P.2
Byrd, D.R.3
-
41
-
-
33744775945
-
Screening for early pancreatic neoplasia in high-risk individuals: A prospective controlled study
-
Canto MI, Goggins M, Hruban RH et al (2006) Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study. Clin Gastroenterol Hepatol 4:766-781
-
(2006)
Clin. Gastroenterol. Hepatol.
, vol.4
, pp. 766-781
-
-
Canto, M.I.1
Goggins, M.2
Hruban, R.H.3
-
42
-
-
27144532118
-
In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor
-
van der Heijden MS, Brody JR, Dezentje DA et al (2005) In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor. Clin Cancer Res 11:7508-7515
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 7508-7515
-
-
Van Der Heijden, M.S.1
Brody, J.R.2
Dezentje, D.A.3
|