Fluorinated anesthetic exposure 'activates' the renal cortical sphingomyelinase cascade

Kidney International

Volumn 54, Issue 2, 1998, Pages 373-381

  Lochhead, Karen M ^b   Zager, Richard A ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b NONE

Author keywords

Ceramide; Desflurane; HK 2 cells; Isoflurane; Sphingomyelin; Sphingosine

Indexed keywords

CERAMIDE; DESFLURANE; FLUORINE DERIVATIVE; ISOFLURANE; PENTOBARBITAL; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HYDROLYSIS; INHALATIONAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0031848825     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00022.x     Document Type: Article

References (51)

1. ZHANG Y, KOLESNICK R: Signaling through the sphingomyelin pathway. Endocrinology 136:4157-4160, 1995
2. HANNUN Y: The sphingomyelin cycle and second messenger function of ceramide. J Biol Chem 269:3125-3128. 1994
3. IESU R: Sphingomyelin breakdown and cell tate. Trends Biochem Sci 21:468-471, 1996
4. HANNUN YA: Functions of ceramide in coordinating cellular responses to stress. Science 274:1855-1859, 1996
5. OBEID LM, HANNUN YA: Ceramide: A stress signal and mediator of growth suppression and apoptosis. J Cell Biochem 58:191-198, 1995
6. MAIHIAS S, KOLLSNIOR R: Ceramide: A novel second messenger. Advances Lipid Res 25:65-90, 1993
7. KIM MY, LINARDIC C, OBEID L, HANNUN YA: Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation. J Biol Chem 266:484-489, 1991
8. 2 production and sphingomyelin metabolism. Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide. J Biol Chem 267:20044-20050, 1992
9. DOBROWSKY RT, WERNER MH, CASTELLINO AM, CHAO MV, HANUN YA: Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265:1596-1599, 1994
10. 3-induced HL-60 cell differentiation. J Biol Chem 265:15823-15831, 1990
11. STRUM JC, SMALL G, PAUIG SB, DANIEL LW: 1-beta-D arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells. J Biol Chem 269:15493-15497, 1994
12. ZHANG J, ALTER N, REED JC, BORNER C, OBEID LM, HANNUN YA: Bcl-2 interrupts the ceramide-mediated pathway of cell death. Proc Natl Acad Sci USA 93:5325-5328, 1996
13. JAYADEV S, LIU B, BIELAWSKA AE, LEE JY, NAZAIRE R, PUSHKAREVA M, OBEID LM, HANNUN YA: Role of ceramide in cell cycle arrest. J Biol Chem 270:2047-2052, 1994
14. DOBROWSKY RT, KAMIBAYASHI C, MUMBY MC, HANNUN YA: Ceramide activates heterotrimeric protein phosphatase 2A. J Biol Chem 268:15523-15530, 1993
15. GOLDKORN T, DRESSLER KA, MUINDI J, RADIN NS, MENDELSOHN J, MENALDINO D, LIOTTA D, KOLESNICK RN: Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action. J Biol Chem 266:16092-16097, 1991
16. KYRIAKIS JM, BANERJEE P, NIKIOLOKAKI E, DAI T, RUBIE EA, AHMAD MF, AVRUCH J, WOODGETT JR: The stress-activated protein kinase subfamily of c-Jun kinases. Nature (Lond) 369:156-160, 1994
17. SPIEGEL S, MERRILL AH JR: Sphingolipid metabolism and cell growth regulation. FASEB J 10:1388-1397, 1996
18. SABA JD, OBEID LM, HANNUN YA: Ceramide: An intracellular mediator of apoptosis and growth suppression. Phil Trans Royal Society of London-Series B: Biol Sci 351:233-240, 1996
19. SPIEGEL S, MILSTIEN S: Sphingoid bases and phospholipase D activation. Chem Phys Lipids 80:27-36, 1996
20. HANNUN YA, LOOMIS CR, MERRILL AH JR, BELL RM: Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J Biol Chem 261:12604-12609, 1986
21. RANI CS, WANG F, FUIOR E, BERGER A, WU J, STURGILL TW, BEITNER-JOHNSON D, LEROITH D, VARTICOVSKI L, SPIEGEL S: Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling. J Biol Chem 272:10777-10783, 1997
22. MERRILL AH JR, SCHMELZ EM, DILLEHAY DL, SPIEGEL S, SHAYMAN JA, SCHROEDER JJ, RILEY RT, VOSS KA, WANG E: Sphingolipids-the enigmatic lipid class: Biochemistry, physiology and pathophysiology. Toxicol Appl Ther 142:208-225, 1997
23. SPIEGEL S, FOSTER D, KOLESNICK R: Signal transduction through lipid second messengers. Curr Opin Cell Biol 8:159-167, 1996
24. CUVILLIER O, PIRIANOV G, KLEUSER B, VANEK PG, COSO OA, GUTKIND S, SPIEGEL S: Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature (Lond) 381: 800-803, 1996
25. PELLKOFER R, SANDHOFF K: Halothane increases membrane fluidity and stimulates sphingomyelinase degradation by membrane-bound neutral sphingomyelinase of synaptosomal plasma membranes from calf brain already at clinical concentrations. J Neurochem 34:988-992, 1980
26. MOOIBROEK MJ, COOK HW, CLARKE JTR, SPENCE MW: Catabolism of exogenous and endogenous sphingomyelin and phosphatidylcholine by homogenates and subcellular fractions of cultured neuroblastoma cells. Effects of anesthetics. J Neurochem 44:1551-1558, 1985
27. MATTHYS E, PATEL Y, KREISBERG J, STEWART JH, VENKATACHALAM MA: Lipid alterations induced by renal ischemia: Pathogenic factor in membrane damage. Kidney Int 26:153-161, 1984
28. MARSHALL BE, LONGNECKER DE: General anesthetics, in Goodman and Gilman's The Pharmacologic Basis of Therapeutics (9th ed), New York, McGraw-Hill, 1996, pp 307-330
29. FINN WF: Nephron heterogeneity in polyuric acute renal failure. J Lab Clin Med 98:21-29, 1981
30. LOCHHEAD KM, KHARASCH ED, ZAGER RA: Anesthetic effects on the glycerol model of rhabdomyolysis-induced acute renal failure in rats. J Am Soc Nephrol 9:305-309, 1998
31. CRANDALL WB, PAPPAS SG, MCDONALD A: Nephrotoxicity associated with methoxyflurane anesthesia. Anesthesiology 27:591-607, 1966
32. HOLLENBERG NK, MCDONALD FD, COTRAN R, GALVANEK EG, WAHOL M, VANDAM LD, MERRILL JP: Irreversible acute oliguric renal failure: A complication of methoxyflurane anesthesia. N Engl J Med 286:877-879, 1972
33. LOCHHEAD KM, KHARASCH ED, ZAGER RA: Spectrum and subcellular determinants of fluorinated anesthetic-mediated proximal tubular injury. Am J Pathol 150:2209-2221, 1997
34. ZAGER RA, IWATA M, CONRAD DS, BURKHART KM, IGARASHI Y: Altered ceramide and sphingosine expression during the induction of ischemic acute renal failure. Kidney Int 52:60-70, 1997
35. 1 cells. (abstract) J Am Soc Nephrol 8:418A, 1997
36. ZAGER RA, IWATA M: Inorganic fluoride: divergent effects on human proximal tubular cell viability. Am J Pathol 150:734-745, 1997
37. YOUNES A, KAHN DW, BESTERMAN WR, BITTMAN R, BYUN H-S, KOLESNICK RN: Ceramide is a competitive inhibitor of diacylglycerokinase in vitro and in intact human leukemia (HL-60) cells. J Biol Chem 267:842-847, 1992
38. VAN VELDHOVEN PP, MANNAERTS GP: Inorganic and organic phosphate measurements in the nanomolar range. Anal Biochem 161:45-48, 1987
39. MERRILL AH JR, WANG E, MULLINS RE, JAMISON WCL, NIMKAR S, LIOTTA DC: Quantitation of free sphingosine in liver by high performance liquid chromatography. Anal Biochem 171:373-381, 1988
40. RYAN MJ, JOHNSON G, KIRK J, FUERSTENBERG SM, ZAGER RA, TOROK-STORB B: HK-2 an immortalied proximal tubule eptihelial cell line from normal human kidney. Kidney Int 45:48-57, 1994
41. CHATTERJEE S, GHOSH N: Purification of neutral sphingomyelinase from human urine. Method Enzymol 197:540-547, 1991
42. QUINTERN LE, SANDHOFF K: Human acid sphingomyelinase from human urine. Method Enzymol 197:536-540, 1991
43. ZAGER RA, CONRAD DS, LOCHHEAD KM, SWEENEY EA, IGARASHI I, BURKHART KM: Altered sphingomyelinase and ceramide expression in the setting of ischemic and nephrotoxic acute renal failure. Kidney Int 53:573-582, 1998
44. SORGER PK: Heat shock factor and the heat shock response. Cell 65:363-366, 1991
45. LINDQUIST S: The heat shock response. Annu Rev Biochem 55:1151-1191, 1986
46. 2 deprivation injury, possibly by inducing uremia. Kidney Int 45:1760-1768, 1994
47. CHANG Y, ABE A, SHAYMAN JA: Ceramide formation during heat shock: A potential mediator of αB-crystallin transcription. Proc Natl Acad Sci USA 92:12275-12279, 1995
48. BOSE R, VERHEIJ M, HAIMOVITZ-FRIEDMAN A, SCOTTO K, FUKS Z, KOLESNICK R: Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals. Cell 82:405-414, 1995
49. IWATA M, HERRINGTON J, ZAGER RA: Sphingosine: A mediator of acute renal tubular injury and subsequent cytoresistance. Proc Nat Acad Sci USA 92:8970-8974, 1995
50. NOIRI E, ROMANOV V, GAILIT J, DIBONA GF, MILLER F, SOM P, OSTER ZH, GOLIGORSKY MS: Pathophysiology of renal tubular obstruction: Therapeutic role of synthetic RGD peptides in acute renal failure. Kidney Int 48:1375-1385, 1995
51. HONDA I, YONEMURA K: Acquired resistance to acute renal failure. Kidney Int 31:1233-1238, 1987