메뉴 건너뛰기




Volumn 96, Issue 6, 2011, Pages 918-921

Outcome of patients with chronic myeloid leukemia with multiple ABL1 kinase domain mutations receiving tyrosine kinase inhibitor therapy

Author keywords

ABL1 mutation; CML; Multiple mutations; Tyrosine kinase inhibitor

Indexed keywords

BAFETINIB; BOSUTINIB; DASATINIB; IMATINIB; NILOTINIB; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 79958056962     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2010.039321     Document Type: Article
Times cited : (17)

References (21)
  • 1
    • 4344672552 scopus 로고    scopus 로고
    • Imatinib therapy in chronic myelogenous leukemia: Strategies to avoid and overcome resistance
    • Hochhaus A, La Rosee P. Imatinib therapy in chronic myelogenous leukemia: strategies to avoid and overcome resistance. Leukemia. 2004;18(8):1321-31.
    • (2004) Leukemia , vol.18 , Issue.8 , pp. 1321-1331
    • Hochhaus, A.1    la Rosee, P.2
  • 2
    • 0001686739 scopus 로고    scopus 로고
    • Multiple BCRABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
    • Shah NP, Nicoll JM, Nagar B, Gorre ME, Paquette RL, Kuriyan J, et al. Multiple BCRABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell. 2002;2(2):117-25.
    • (2002) Cancer Cell , vol.2 , Issue.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3    Gorre, M.E.4    Paquette, R.L.5    Kuriyan, J.6
  • 3
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, Hsu N, Paquette R, Rao PN, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science. 2001;293(5531):876-80.
    • (2001) Science , vol.293 , Issue.5531 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3    Hsu, N.4    Paquette, R.5    Rao, P.N.6
  • 4
    • 19244366937 scopus 로고    scopus 로고
    • Minimal residual disease in chronic myeloid leukemia
    • Lowenberg B. Minimal residual disease in chronic myeloid leukemia. N Engl J Med. 2003;349(15):1399-401.
    • (2003) N Engl J Med , vol.349 , Issue.15 , pp. 1399-1401
    • Lowenberg, B.1
  • 5
    • 0038375012 scopus 로고    scopus 로고
    • Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib
    • Corbin AS, La Rosee P, Stoffregen EP, Druker BJ, Deininger MW. Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib. Blood. 2003;101(11):4611-4.
    • (2003) Blood , vol.101 , Issue.11 , pp. 4611-4614
    • Corbin, A.S.1    la Rosee, P.2    Stoffregen, E.P.3    Druker, B.J.4    Deininger, M.W.5
  • 7
    • 61849163272 scopus 로고    scopus 로고
    • Molecular biology of bcr-abl1-positive chronic myeloid leukemia
    • Quintas-Cardama A, Cortes J. Molecular biology of bcr-abl1-positive chronic myeloid leukemia. Blood. 2009;113(8):1619-30.
    • (2009) Blood , vol.113 , Issue.8 , pp. 1619-1630
    • Quintas-Cardama, A.1    Cortes, J.2
  • 8
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H, Resta DJ, Reese SF, Ford JM, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001;344(14):1038-42.
    • (2001) N Engl J Med , vol.344 , Issue.14 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3    Resta, D.J.4    Reese, S.F.5    Ford, J.M.6
  • 10
    • 33745086350 scopus 로고    scopus 로고
    • Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
    • Kantarjian H, Giles F, Wunderle L, Bhalia K, O'Brien S, Wassmann B, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med. 2006;354(24):2542-51.
    • (2006) N Engl J Med , vol.354 , Issue.24 , pp. 2542-2551
    • Kantarjian, H.1    Giles, F.2    Wunderle, L.3    Bhalia, K.4    O'brien, S.5    Wassmann, B.6
  • 11
    • 33745102555 scopus 로고    scopus 로고
    • Dasatinib in imatinib-resistant Philadelphia chromosomepositive leukemias
    • Talpaz M, Shah NP, Kantarjian H, Donato N, Nicoli J, Paquette J, et al. Dasatinib in imatinib-resistant Philadelphia chromosomepositive leukemias. N Engl J Med. 2006;354 (24):2531-41.
    • (2006) N Engl J Med , vol.354 , Issue.24 , pp. 2531-2541
    • Talpaz, M.1    Shah, N.P.2    Kantarjian, H.3    Donato, N.4    Nicoli, J.5    Paquette, J.6
  • 12
    • 19944428353 scopus 로고    scopus 로고
    • Discovery of N- (2-chloro-6-methyl-phenyl)-2-(6-(4-(2-hy -dro xyethyl)-piperazin-1-yl)-2-methyl -pyrimidin-4- ylamino)thiazole-5-carbo -xamide (BMS-354825), a dual Src/Abl kinaseinhibitor with potent antitumor activity in preclinical assays
    • Lombardo LJ, Lee FY, Chen P, Norris D, Barrish JC, Behnia K, et al. Discovery of N- (2-chloro-6-methyl-phenyl)-2-(6-(4-(2-hy -dro xyethyl)-piperazin-1-yl)-2-methyl -pyrimidin-4- ylamino)thiazole-5-carbo -xamide (BMS-354825), a dual Src/Abl kinaseinhibitor with potent antitumor activity in preclinical assays. J Med Chem. 2004;47(27): 6658-61.
    • (2004) J Med Chem , vol.47 , Issue.27 , pp. 6658-6661
    • Lombardo, L.J.1    Lee, F.Y.2    Chen, P.3    Norris, D.4    Barrish, J.C.5    Behnia, K.6
  • 13
    • 3142676436 scopus 로고    scopus 로고
    • Overriding imatinib resistance with a novel ABL kinase inhibitor
    • Shah NP, Tran C, Lee FY, Chen P, Norris D, Sawyers CL. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science. 2004;305(5682):399-401.
    • (2004) Science , vol.305 , Issue.5682 , pp. 399-401
    • Shah, N.P.1    Tran, C.2    Lee, F.Y.3    Chen, P.4    Norris, D.5    Sawyers, C.L.6
  • 14
    • 76249090055 scopus 로고    scopus 로고
    • Selecting optimal second-line tyrosine kinaseinhibitor therapy for chronic myeloid leukemia patients after imatinib failure: Does the BCR-ABL mutation status really matter?
    • Branford S, Melo JV, Hughes TP. Selecting optimal second-line tyrosine kinaseinhibitor therapy for chronic myeloid leukemia patients after imatinib failure: does the BCR-ABL mutation status really matter? Blood. 2009;114(27):5426-35.
    • (2009) Blood , vol.114 , Issue.27 , pp. 5426-5435
    • Branford, S.1    Melo, J.V.2    Hughes, T.P.3
  • 15
    • 34848911943 scopus 로고    scopus 로고
    • Sequential BL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutationswith altered oncogenic potency
    • Shah NP, Skaggs BJ, Branford S, Hughes TP, Nicoli JM, Paquette RL, et al. Sequential BL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutationswith altered oncogenic potency. J Clin Invest. 2007;117(9):2562-9.
    • (2007) J Clin Invest , vol.117 , Issue.9 , pp. 2562-2569
    • Shah, N.P.1    Skaggs, B.J.2    Branford, S.3    Hughes, T.P.4    Nicoli, J.M.5    Paquette, R.L.6
  • 16
    • 10744232328 scopus 로고    scopus 로고
    • Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompaniedby clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
    • Branford S, Rudzki Z, Walsh S, Parkinson I, Grigg A, Szer J, et al. Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompaniedby clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis. Blood. 2003;102(1):276-83.
    • (2003) Blood , vol.102 , Issue.1 , pp. 276-283
    • Branford, S.1    Rudzki, Z.2    Walsh, S.3    Parkinson, I.4    Grigg, A.5    Szer, J.6
  • 17
    • 33746934638 scopus 로고    scopus 로고
    • Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib
    • Griswold IJ, MacPartlin M, Bumm T, Goss VL, O'Hare T, Lee KA, et al. Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib. Mol Cell Biol. 2006;26(16):6082- 93.
    • (2006) Mol Cell Biol , vol.26 , Issue.16 , pp. 6082-6093
    • Griswold, I.J.1    Macpartlin, M.2    Bumm, T.3    Goss, V.L.4    O'Hare, T.5    Lee, K.A.6
  • 18
    • 70349254450 scopus 로고    scopus 로고
    • Philadelphiapositive patients who already harbor imatinib-resistant Bcr-Abl kinase domain mutations have a higher likelihood of developing additional mutations associated with resistance to second- or third-line tyrosine kinase inhibitors
    • Soverini S, Gnani A, Colarossi S, Castagnetti F, Abruzzese E, Paolini S, et al. Philadelphiapositive patients who already harbor imatinib-resistant Bcr-Abl kinase domain mutations have a higher likelihood of developing additional mutations associated with resistance to second- or third-line tyrosine kinase inhibitors. Blood. 2009;114(10):2168-71.
    • (2009) Blood , vol.114 , Issue.10 , pp. 2168-2171
    • Soverini, S.1    Gnani, A.2    Colarossi, S.3    Castagnetti, F.4    Abruzzese, E.5    Paolini, S.6
  • 19
    • 70350507997 scopus 로고    scopus 로고
    • AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
    • O'Hare T, Shakespeare WC, Zhu X, Eide CA, Rivera VM, Wang F, et al. AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell. 2009;16(5):401-12.
    • (2009) Cancer Cell , vol.16 , Issue.5 , pp. 401-412
    • O'Hare, T.1    Shakespeare, W.C.2    Zhu, X.3    Eide, C.A.4    Rivera, V.M.5    Wang, F.6
  • 20
    • 33745603988 scopus 로고    scopus 로고
    • Monitor - ing CML patients responding to treatment with tyrosine kinase inhibitors: Review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
    • Hughes T, Deininger M, Hochhaus A, Branford S, Radich J, Kaeda J, et al. Monitor - ing CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood. 2006;108(1):28-37.
    • (2006) Blood , vol.108 , Issue.1 , pp. 28-37
    • Hughes, T.1    Deininger, M.2    Hochhaus, A.3    Branford, S.4    Radich, J.5    Kaeda, J.6
  • 21
    • 65249092711 scopus 로고    scopus 로고
    • Mutational analysis of chronic myeloid leukemia (CML) clones reveals heightened BCR-ABL1 genetic instability and wild-type BCR-ABL1 exhaustion in patients failing sequential imatinib and dasatinib therapy
    • abstract 1938
    • Quintas-Cardama AG, Gibbons DL, Kantarjian H, et al. Mutational analysis of chronic myeloid leukemia (CML) clones reveals heightened BCR-ABL1 genetic instability and wild-type BCR-ABL1 exhaustion in patients failing sequential imatinib and dasatinib therapy. Blood. 2007;110:(abstract 1938).
    • (2007) Blood , pp. 110
    • Quintas-Cardama, A.G.1    Gibbons, D.L.2    Kantarjian, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.