Dual protective mechanisms of matrix metalloproteinases 2 and 9 in immune defense against Streptococcus pneumoniae

Journal of Immunology

Volumn 186, Issue 11, 2011, Pages 6427-6436

  Hong, Jeong Soo ^a   Greenlee, Kendra J ^a   Pitchumani, Ramanan ^b   Lee, Seung Hyo ^c   Song, Li Zhen ^a   Shan, Ming ^a   Chang, Seon Hee ^d   Park, Pyong Woo ^e   Dong, Chen ^d   Werb, Zena ^f   Bidani, Akhil ^b   Corry, David B ^a   Kheradmand, Farrah ^a,g  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b University of Houston   (United States)

^c Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; GELATINASE A; GELATINASE B; INTERLEUKIN 17; RANTES; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL LOAD; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME DEGRADATION; FIBROBLAST; HOST RESISTANCE; INNATE IMMUNITY; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; SURVIVAL; TISSUE LEVEL; WILD TYPE;

ANIMALS; CHEMOKINE CCL5; CHEMOKINE CXCL10; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; INTERLEUKIN-17; KAPLAN-MEIER ESTIMATE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTIONS; PNEUMONIA; REACTIVE OXYGEN SPECIES; STREPTOCOCCUS PNEUMONIAE;

EID: 79958032102     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003449     Document Type: Article

References (41)

1. Kadioglu, A., J. N. Weiser, J. C. Paton, and P. W. Andrew. 2008. The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat. Rev. Microbiol. 6: 288-301.
2. Silva, M. T. 2010. Neutrophils and macrophages work in concert as inducers and effectors of adaptive immunity against extracellular and intracellular microbial pathogens. J. Leukoc. Biol. 87: 805-813.
3. Weiser, J. N. 2010. The pneumococcus: why a commensal misbehaves. J. Mol. Med. 88: 97-102.
4. Chang, S. H., and C. Dong. 2009. IL-17F: regulation, signaling and function in inflammation. Cytokine 46: 7-11.
5. Furze, R. C., and S. M. Rankin. 2008. Neutrophil mobilization and clearance in the bone marrow. Immunology 125: 281-288.
6. Kolls, J. K. 2010. Th17 cells in mucosal immunity and tissue inflammation. Semin. Immunopathol. 32: 1-2.
7. Matthias, K. A., A. M. Roche, A. J. Standish, M. Shchepetov, and J. N. Weiser. 2008. Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae. J. Immunol. 180: 6246-6254.
8. Mayadas, T. N., G. C. Tsokos, and N. Tsuboi. 2009. Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury. Circulation 120: 2012-2024.
9. Segal, A.W. 2005. How neutrophils kill microbes. Annu. Rev. Immunol. 23: 197-223.
10. Soehnlein, O., C. Weber, and L. Lindbom. 2009. Neutrophil granule proteins tune monocytic cell function. Trends Immunol. 30: 538-546.
11. Papayannopoulos, V., and A. Zychlinsky. 2009. NETs: a new strategy for using old weapons. Trends Immunol. 30: 513-521.
12. Kennedy, A. D., and F. R. DeLeo. 2009. Neutrophil apoptosis and the resolution of infection. Immunol. Res. 43: 25-61.
13. Standish, A. J., and J. N. Weiser. 2009. Human neutrophils kill Streptococcus pneumoniae via serine proteases. J. Immunol. 183: 2602-2609.
14. Greenlee, K. J., Z. Werb, and F. Kheradmand. 2007. Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol. Rev. 87: 69-98.
15. McQuibban, G. A., G. S. Butler, J. H. Gong, L. Bendall, C. Power, I. Clark-Lewis, and C. M. Overall. 2001. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. J. Biol. Chem. 276: 43503-43508.
16. McCawley, L. J., and L. M. Matrisian. 2001. Matrix metalloproteinases: they're not just for matrix anymore! Curr. Opin. Cell Biol. 13: 534-540.
17. Greenlee, K. J., D. B. Corry, D. A. Engler, R. K. Matsunami, P. Tessier, R. G. Cook, Z. Werb, and F. Kheradmand. 2006. Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation. J. Immunol. 177: 7312-7321. (Pubitemid 44715101)
18. McQuibban, G. A., J. H. Gong, J. P. Wong, J. L. Wallace, I. Clark-Lewis, and C. M. Overall. 2002. Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo. Blood 100: 1160-1167.
19. Van Den Steen, P. E., A. Wuyts, S. J. Husson, P. Proost, J. Van Damme, and G. Opdenakker. 2003. Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities. Eur. J. Biochem. 270: 3739-3749.
20. Renckens, R., J. J. T. H. Roelofs, S. Florquin, A. F. de Vos, H. R. Lijnen, C. van't Veer, and T. van der Poll. 2006. Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis. J. Immunol. 176: 3735-3741.
21. Corry, D. B., A. Kiss, L. Z. Song, L. Song, J. Xu, S. H. Lee, Z. Werb, and F. Kheradmand. 2004. Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines. FASEB J. 18: 995-997 (Pubitemid 39561503)
22. Aaberge, I. S., J. Eng, G. Lermark, and M. Løvik. 1995. Virulence of Streptococcus pneumoniae in mice: a standardized method for preparation and frozen storage of the experimental bacterial inoculum. Microb. Pathog. 18: 141-152.
23. Tettelin, H., K. E. Nelson, I. T. Paulsen, J. A. Eisen, T. D. Read, S. Peterson, J. Heidelberg, R. T. DeBoy, D. H. Haft, R. J. Dodson, et al. 2001. Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science 293: 498-506. (Pubitemid 32679078)
24. Park, P.W., G. B. Pier, M. T. Hinkes, and M. Bernfield. 2001. Exploitation of syndecan- 1 shedding by Pseudomonas aeruginosa enhances virulence. Nature 411: 98-102. (Pubitemid 32428197)
25. Bubeck Wardenburg, J., R. J. Patel, and O. Schneewind. 2007. Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia. Infect. Immun. 75: 1040-1044.
26. Corry, D. B., K. Rishi, J. Kanellis, A. Kiss, L. Z. Song Lz, J. Xu, L. Feng, Z. Werb, and F. Kheradmand. 2002. Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency. Nat. Immunol. 3: 347-353.
27. Luo, Y., and M. E. Dorf. 2001. Isolation of mouse neutrophils. Curr. Protoc. Immunol. May: Chapter 3, Unit 3.20.
28. Clemens, R. A., S. A. Newbrough, E. Y. Chung, S. Gheith, A. L. Singer, G. A. Koretzky, and E. J. Peterson. 2004. PRAM-1 is required for optimal integrin-dependent neutrophil function. Mol. Cell. Biol. 24: 10923-10932.
29. Dahlgren, C., and A. Karlsson. 1999. Respiratory burst in human neutrophils. J. Immunol. Methods 232: 3-14. (Pubitemid 30017761)
30. Parks, W. C., C. L. Wilson, and Y. S. López-Boado. 2004. Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat. Rev. Immunol. 4: 617-629.
31. Dong, C. 2008. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat. Rev. Immunol. 8: 337-348.
32. Chang, S. H., H. Park, and C. Dong. 2006. Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor. J. Biol. Chem. 281: 35603-35607.
33. Houghton, A. M., W. O. Hartzell, C. S. Robbins, F. X. Gomis-Rüth, and S. D. Shapiro. 2009. Macrophage elastase kills bacteria within murine macrophages. Nature 460: 637-641.
34. Zhang, Z., T. B. Clarke, and J. N. Weiser. 2009. Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice. J. Clin. Invest. 119: 1899-1909.
35. Chang, S. H., and C. Dong. 2007. A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses. Cell Res. 17: 435-440. (Pubitemid 46763094)
36. Kolls, J. K., P. B. McCray, Jr., and Y. R. Chan. 2008. Cytokine-mediated regulation of antimicrobial proteins. Nat. Rev. Immunol. 8: 829-835.
37. Shen, F., M. J. Ruddy, P. Plamondon, and S. L. Gaffen. 2005. Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-alpha- induced genes in bone cells. J. Leukoc. Biol. 77: 388-399.
38. Park, H., Z. Li, X. O. Yang, S. H. Chang, R. Nurieva, Y. H. Wang, Y. Wang, L. Hood, Z. Zhu, Q. Tian, and C. Dong. 2005. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6: 1133-1141.
39. Malik, M., C. S. Bakshi, K. McCabe, S. V. Catlett, A. Shah, R. Singh, P. L. Jackson, A. Gaggar, D. W. Metzger, J. A. Melendez, et al. 2007. Matrix metalloproteinase 9 activity enhances host susceptibility to pulmonary infection with type A and B strains of Francisella tularensis. J. Immunol. 178: 1013-1020. (Pubitemid 46095174)
40. Manicone, A. M., T. P. Birkland, M. Lin, T. Betsuyaku, N. van Rooijen, J. Lohi, J. Keski-Oja, Y. Wang, S. J. Skerrett, and W. C. Parks. 2009. Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas aeruginosa pneumonia. J. Immunol. 182: 3866-3876.
41. Wilson, C. L., A. J. Ouellette, D. P. Satchell, T. Ayabe, Y. S. López-Boado, J. L. Stratman, S. J. Hultgren, L. M. Matrisian, and W. C. Parks. 1999. Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science 286: 113-117.