Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library

Peptides

Volumn 32, Issue 6, 2011, Pages 1232-1243

  Larbanoix, Lionel ^a   Burtea, Carmen ^a   Ansciaux, Emilie ^a   Laurent, Sophie ^a   Mahieu, Isabelle ^a   Vander Elst, Luce ^a   Muller, Robert N ^a  

^a UNIVERSITY OF MONS   (Belgium)

Author keywords

Alzheimer's disease; Amyloid plaques; Amyloid beta; High throughput screening; Phage display

Indexed keywords

AMYLOID; HEPTAPEPTIDE; PEPTIDE LIBRARY; THIOFLAVINE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID PLAQUE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DISEASE MODEL; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHAGE DISPLAY; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; ANIMALS; BIOTINYLATION; BLOOD-BRAIN BARRIER; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; KINETICS; MAGNETIC RESONANCE IMAGING; MICE; MICE, TRANSGENIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR TARGETED THERAPY; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PEPTIDES, CYCLIC; PLAQUE, AMYLOID; PROTEIN BINDING; SEQUENCE ANALYSIS, DNA; THIAZOLES;

EID: 79958015124     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2011.04.026     Document Type: Article

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