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Volumn 9, Issue 12, 2011, Pages 4487-4497
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Sialic acid C-glycosides with aromatic residues: Investigating enzyme binding and inhibition of Trypanosoma cruzi trans-sialidase
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Author keywords
[No Author keywords available]
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Indexed keywords
ACTIVE SITE;
AROMATIC RESIDUES;
C-GLYCOSIDES;
CHAGAS DISEASE;
CROSS METATHESIS;
DERIVATISATION;
ENZYME BINDING;
INHIBITION ASSAYS;
KEY ENZYMES;
MILLIMOLAR RANGE;
SIALIC ACIDS;
SIDE-CHAINS;
TRANS-SIALIDASES;
TRYPANOSOMA CRUZI;
AMINO ACIDS;
CARBOXYLIC ACIDS;
CHELATION;
LIGANDS;
NUCLEAR MAGNETIC RESONANCE;
SUGARS;
SURFACE PLASMON RESONANCE;
ENZYME INHIBITION;
ENZYME INHIBITOR;
GLYCOPROTEIN;
GLYCOSIDE;
IMMOBILIZED ENZYME;
LIGAND;
SIALIC ACID DERIVATIVE;
SIALIDASE;
TRANS SIALIDASE;
TRANS-SIALIDASE;
ARTICLE;
BINDING SITE;
CHAGAS DISEASE;
CHEMICAL PHENOMENA;
CHEMICAL STRUCTURE;
CHEMISTRY;
DRUG ANTAGONISM;
DRUG EFFECT;
ENZYME ACTIVE SITE;
ENZYMOLOGY;
HUMAN;
KINETICS;
METABOLISM;
METHODOLOGY;
NUCLEAR MAGNETIC RESONANCE;
PARASITOLOGY;
PROTEIN BINDING;
SURFACE PLASMON RESONANCE;
SYNTHESIS;
TRYPANOSOMA CRUZI;
BINDING SITES;
CATALYTIC DOMAIN;
CHAGAS DISEASE;
CHEMISTRY, PHARMACEUTICAL;
ENZYME INHIBITORS;
ENZYMES, IMMOBILIZED;
GLYCOPROTEINS;
GLYCOSIDES;
HUMANS;
HYDROPHOBIC AND HYDROPHILIC INTERACTIONS;
KINETICS;
LIGANDS;
MODELS, MOLECULAR;
NEURAMINIDASE;
NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;
PROTEIN BINDING;
SIALIC ACIDS;
SURFACE PLASMON RESONANCE;
TRYPANOSOMA CRUZI;
TRYPANOSOMA CRUZI;
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EID: 79958005289
PISSN: 14770520
EISSN: None
Source Type: Journal
DOI: 10.1039/c0ob01176b Document Type: Article |
Times cited : (21)
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References (27)
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