Large scale RNAi screen reveals that the inhibitor of DNA binding 2 (ID2) protein is repressed by p53 family member p63 and functions in human keratinocyte differentiation

Journal of Biological Chemistry

Volumn 286, Issue 23, 2011, Pages 20870-20879

  Wu, Ning ^a,b   Castel, David ^a   Debily, Marie Anne ^b,c   Vigano, Maria Alessandra ^d   Alibert, Olivier ^b   Mantovani, Roberto ^d   Iljin, Kristina ^e   Romeo, Paul Henri ^b   Gidrol, Xavier ^a,b  

^a CEA GRENOBLE   (France)

^b DIF   (France)

^c UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^d UNIVERSITY OF MILAN   (Italy)

^e UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE; CELL-CYCLE PROGRESSION; DNA BINDING; DOMINANT NEGATIVE; ELEVATED LEVEL; EPITHELIAL DEVELOPMENT; GENE PROMOTER; HELIX-LOOP-HELIX PROTEINS; IN-VITRO; INHIBITORY MECHANISM; KERATINOCYTE DIFFERENTIATION; KERATINOCYTES; PROMOTER ACTIVITIES; TRANSCRIPT LEVEL; UPSTREAM REGION;

GENES; NUCLEIC ACIDS; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

GENE PRODUCT; GREEN FLUORESCENT PROTEIN; INHIBITOR OF DIFFERENTIATION 2; PROTEIN NBN; PROTEIN P53; PROTEIN P63; PROTEIN RAD21; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE REPRESSION; GENE SILENCING; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; ID2 GENE; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; LOSS OF FUNCTION MUTATION; MICROARRAY ANALYSIS; MITOSIS INHIBITION; NBN GENE; ONCOGENE; P63 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; RAD21 GENE; REGULATOR GENE;

CELL CYCLE PROTEINS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 2; KERATINOCYTES; MITOSIS; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 79958003061     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.169433     Document Type: Article

References (57)

1. Yokota, Y., and Mori, S. (2002) J. Cell Physiol. 190, 21-28
2. Ruzinova, M. B., and Benezra, R. (2003) Trends Cell Biol. 13, 410-418
3. Perk, J., Iavarone, A., and Benezra, R. (2005) Nat. Rev Cancer 5, 603-614
4. Langlands, K., Yin, X., Anand, G., and Prochownik, E. V. (1997) J. Biol. Chem. 272, 19785-19793
5. Ohtani, N., Zebedee, Z., Huot, T. J., Stinson, J. A., Sugimoto, M., Ohashi, Y., Sharrocks, A. D., Peters, G., and Hara, E. (2001) Nature 409, 1067-1070
6. Norton, J. D., Deed, R. W., Craggs, G., and Sablitzky, F. (1998) Trends Cell Biol. 8, 58-65
7. Lasorella, A., Noseda, M., Beyna, M., Yokota, Y., and Iavarone, A. (2000) Nature 407, 592-598
8. Kleeff, J., Ishiwata, T., Friess, H., Büchler, M. W., Israel, M. A., and Korc, M. (1998) Cancer Res. 58, 3769-3772
9. Stighall, M., Manetopoulos, C., Axelson, H., and Landberg, G. (2005) Int. J. Cancer 115, 403-411
10. Alaminos, M., Gerald, W. L., and Cheung, N. K. (2005) Pediatr. Blood Cancer 45, 909-915
11. Asirvatham, A. J., Carey, J. P., and Chaudhary, J. (2007) Prostate 67, 1411-1420
12. Rollin, J., Bléchet, C., Régina, S., Tenenhaus, A., Guyétant, S., and Gidrol, X. (2009) PLoS ONE 4, e4158
13. Baghdoyan, S., Lamartine, J., Castel, D., Pitaval, A., Roupioz, Y., Franco, N., Duarte, M., Martin, M. T., and Gidrol, X. (2005) J. Biol. Chem. 280, 15836-15841
14. Memezawa, A., Takada, I., Takeyama, K., Igarashi, M., Ito, S., Aiba, S., Kato, S., and Kouzmenko, A. P. (2007) Oncogene 26, 5038-5045
15. Kowanetz, M., Valcourt, U., Bergström, R., Heldin, C. H., and Moustakas, A. (2004) Mol. Cell Biol. 24, 4241-4254
16. Rotzer, D., Krampert, M., Sulyok, S., Braun, S., Stark, H. J., Boukamp, P., and Werner, S. (2006) Oncogene 25, 2070-2081
17. Tokuriki, A., Iyoda, T., Inaba, K., Ikuta, K., Fujimoto, S., Kumakiri, M., and Yokota, Y. (2009) Carcinogenesis 30, 1645-1650
18. Scobey, M. J., Fix, C. A., and Walker, W. H. (2004) J. Biol. Chem. 279, 16064-16070
19. Belletti, B., Prisco, M., Morrione, A., Valentinis, B., Navarro, M., and Baserga, R. (2001) J. Biol. Chem. 276, 13867-13874
20. Rockman, S. P., Currie, S. A., Ciavarella, M., Vincan, E., Dow, C., Thomas, R. J., and Phillips, W. A. (2001) J. Biol. Chem. 276, 45113-45119
21. Hacker, C., Kirsch, R. D., Ju, X. S., Hieronymus, T., Gust, T. C., Kuhl, C., Jorgas, T., Kurz, S. M., Rose-John, S., Yokota, Y., and Zenke, M. (2003) Nat. Immunol. 4, 380-386
22. Aza-Blanc, P., Cooper, C. L., Wagner, K., Batalov, S., Deveraux, Q. L., and Cooke, M. P. (2003) Mol. Cell 12, 627-637
23. Whitehurst, A. W., Bodemann, B. O., Cardenas, J., Ferguson, D., Girard, L., Peyton, M., Minna, J. D., Michnoff, C., Hao, W., Roth, M. G., Xie, X. J., and White, M. A. (2007) Nature 446, 815-819
24. Kittler, R., Pelletier, L., Heninger, A. K., Slabicki, M., Theis, M., Miroslaw, L., Poser, I., Lawo, S., Grabner, H., Kozak, K., Wagner, J., Surendranath, V., Richter, C., Bowen, W., Jackson, A. L., Habermann, B., Hyman, A. A., and Buchholz, F. (2007) Nat. Cell Biol. 9, 1401-1412
25. Ebert, B. L., Pretz, J., Bosco, J., Chang, C. Y., Tamayo, P., Galili, N., Raza, A., Root, D. E., Attar, E., Ellis, S. R., and Golub, T. R. (2008) Nature 451, 335-339
26. Berns, K., Hijmans, E. M., Mullenders, J., Brummelkamp, T. R., Velds, A., Heimerikx, M., Kerkhoven, R. M., Madiredjo, M., Nijkamp, W., Weigelt, B., Agami, R., Ge, W., Cavet, G., Linsley, P. S., Beijersbergen, R. L., and Bernards, R. (2004) Nature 428, 431-437
27. Paddison, P. J., Silva, J. M., Conklin, D. S., Schlabach, M., Li, M., Aruleba, S., Balija, V., O'Shaughnessy, A., Gnoj, L., Scobie, K., Chang, K., Westbrook, T., Cleary, M., Sachidanandam, R., McCombie, W. R., Elledge, S. J., and Hannon, G. J. (2004) Nature 428, 427-431
28. Schlabach, M. R., Luo, J., Solimini, N. L., Hu, G., Xu, Q., Li, M. Z., Zhao, Z., Smogorzewska, A., Sowa, M. E., Ang, X. L., Westbrook, T. F., Liang, A. C., Chang, K., Hackett, J. A., Harper, J. W., Hannon, G. J., and Elledge, S. J. (2008) Science 319, 620-624
29. Baghdoyan, S., Roupioz, Y., Pitaval, A., Castel, D., Khomyakova, E., Papine, A., Soussaline, F., and Gidrol, X. (2004) Nucleic Acids Res. 32, e77
30. Lim, D. S., Kim, S. T., Xu, B., Maser, R. S., Lin, J., Petrini, J. H., and Kastan, M. B. (2000) Nature 404, 613-617
31. Pati, D., Zhang, N., and Plon, S. E. (2002) Mol. Cell Biol. 22, 8267-8277
32. Toyoda, Y., Furuya, K., Goshima, G., Nagao, K., Takahashi, K., and Yanagida, M. (2002) Curr. Biol. 12, 347-358
33. Zhang, Y., Zhou, J., and Lim, C. U. (2006) Cell Res. 16, 45-54
34. Mills, A. A., Zheng, B., Wang, X. J., Vogel, H., Roop, D. R., and Bradley, A. (1999) Nature 398, 708-713
35. Yang, A., Schweitzer, R., Sun, D., Kaghad, M., Walker, N., Bronson, R. T., Tabin, C., Sharpe, A., Caput, D., Crum, C., and McKeon, F. (1999) Nature 398, 714-718
36. Boukamp, P., Petrussevska, R. T., Breitkreutz, D., Hornung, J., Markham, A., and Fusenig, N. E. (1988) J. Cell Biol. 106, 761-771
37. Livak, K. J., and Schmittgen, T. D. (2001) Methods 25, 402-408
38. Barbieri, C. E., Tang, L. J., Brown, K. A., and Pietenpol, J. A. (2006) Cancer Res. 66, 7589-7597
39. Viganò, M. A., Lamartine, J., Testoni, B., Merico, D., Alotto, D., Castagnoli, C., Robert, A., Candi, E., Melino, G., Gidrol, X., and Mantovani, R. (2006) EMBO J. 25, 5105-5116
40. Viganò, M. A., and Mantovani, R. (2007) Cell Cycle 6, 233-239
41. Truong, A. B., Kretz, M., Ridky, T. W., Kimmel, R., and Khavari, P. A. (2006) Genes Dev. 20, 3185-3197
42. Kilpinen, S., Autio, R., Ojala, K., Iljin, K., Bucher, E., Sara, H., Pisto, T., Saarela, M., Skotheim, R. I., Björkman, M., Mpindi, J. P., Haapa-Paananen, S., Vainio, P., Edgren, H., Wolf, M., Astola, J., Nees, M., Hautaniemi, S., and Kallioniemi, O. (2008) Genome Biol. 9, R139
43. Beretta, C., Chiarelli, A., Testoni, B., Mantovani, R., and Guerrini, L. (2005) Cell Cycle 4, 1625-1631
44. Lasorella, A., Stegmüller, J., Guardavaccaro, D., Liu, G., Carro, M. S., Rothschild, G., de la Torre-Ubieta, L., Pagano, M., Bonni, A., and Iavarone, A. (2006) Nature 442, 471-474
45. Ravasi, T., Suzuki, H., Cannistraci, C. V., Katayama, S., Bajic, V. B., Tan, K., Akalin, A., Schmeier, S., Kanamori-Katayama, M., Bertin, N., Carninci, P., Daub, C. O., Forrest, A. R., Gough, J., Grimmond, S., Han, J. H., Hashimoto, T., Hide, W., Hofmann, O., Kawaji, H., Kubosaki, A., Lassmann, T., van Nimwegen, E., Ogawa, C., Teasdale, R. D., Tegnér, J., Lenhard, B., Teichmann, S. A., Arakawa, T., Ninomiya, N., Murakami, K., Tagami, M., Fukuda, S., Imamura, K., Kai, C., Ishihara, R., Kitazume, Y., Kawai, J., Hume, D. A., Ideker, T., and Hayashizaki, Y. (2010) Cell 140, 744-752
46. McKeon, F. (2004) Genes Dev. 18, 465-469
47. Carroll, D. K., Carroll, J. S., Leong, C. O., Cheng, F., Brown, M., Mills, A. A., Brugge, J. S., and Ellisen, L. W. (2006) Nat. Cell Biol. 8, 551-561
48. Senoo, M., Pinto, F., Crum, C. P., and McKeon, F. (2007) Cell 129, 523-536
49. Simbulan-Rosenthal, C. M., Trabosh, V., Velarde, A., Chou, F. P., Daher, A., Tenzin, F., Tokino, T., and Rosenthal, D. S. (2005) Oncogene 24, 5443-5458
50. Fuchs, E. (2009) Cell Stem Cell 4, 499-502
51. Irwin, M. S., and Kaelin, W. G. (2001) Cell Growth Differ. 12, 337-349
52. Pozzi, S., Zambelli, F., Merico, D., Pavesi, G., Robert, A., Maltère, P., Gidrol, X., Mantovani, R., and Vigano, M. A. (2009) PLoS ONE 4, e5008
53. Helton, E. S., Zhu, J., and Chen, X. (2006) J. Biol. Chem. 281, 2533-2542
54. Liu, G., Nozell, S., Xiao, H., and Chen, X. (2004) Mol. Cell Biol. 24, 487-501
55. Drewelus, I., Göpfert, C., Hippel, C., Dickmanns, A., Damianitsch, K., Pieler, T., and Dobbelstein, M. (2010) Cell Cycle 9, 580-587
56. Lefkimmiatis, K., Caratozzolo, M. F., Merlo, P., D'Erchia, A. M., Navarro, B., Levrero, M., Sbisa, E., and Tullo, A. (2009) Cancer Res. 69, 8563-8571
57. Berglund, L., Björling, E., Oksvold, P., Fagerberg, L., Asplund, A., Al-khalili Szigyarto, C., Persson, A., Ottosson, J., Wernérus, H., Nilsson, P., Lundberg, E., Sivertsson, A., Navani, S., Wester, K., Kampf, C., Hober, S., Pontén, F., Uhlén, M. (2008) Mol. Cell. Proteomics 10, 2019-2027