Primer preactivation of peptidoglycan polymerases

Journal of the American Chemical Society

Volumn 133, Issue 22, 2011, Pages 8528-8530

  Wang, Tsung Shing Andrew ^a,b   Lupoli, Tania J ^b   Sumida, Yuto ^b   Tsukamoto, Hirokazu ^b   Wu, Yihui ^b   Rebets, Yuriy ^a   Kahne, Daniel E ^b   Walker, Suzanne ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL CELLS; BACTERIAL ENZYMES; CELL WALLS; GLYCOSYLTRANSFERASES; PEPTIDOGLYCAN FRAGMENTS; PEPTIDOGLYCANS; POLYMER CHAINS; PRE-ACTIVATION; RATE LIMITING;

BACTERIOLOGY; ENZYMES;

POLYMERS;

PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; PEPTIDOGLYCAN POLYMERASE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVATION; GLYCOPROTEIN SYNTHESIS; PRIMER PREACTIVATION;

CELL WALL; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; POLYMERIZATION;

EID: 79957995476     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2028712     Document Type: Article

References (41)

1. Holtje, J. V. Microbiol. Mol. Biol. Rev. 1998, 62, 181-203
2. Vollmer, W.; Bertsche, U. Biochim. Biophys. Acta 2008, 1778, 1714-1734
3. Sauvage, E.; Kerff, F.; Terrak, M.; Ayala, J. A.; Charlier, P. FEMS Microbiol. Rev. 2008, 32, 234-258
4. Walsh, C. Introduction to Antibiotics In Antibiotics: Actions, Origins, Resistance; ASM Press: Washington, DC, 2003; pp 1-9.
5. Walker, S.; Chen, L.; Hu, Y.; Rew, Y.; Shin, D.; Boger, D. L. Chem. Rev. 2005, 105, 449-476
6. Kahne, D.; Leimkuhler, C.; Lu, W.; Walsh, C. Chem. Rev. 2005, 105, 425-448
7. Halliday, J.; McKeveney, D.; Muldoon, C.; Rajaratnam, P.; Meutermans, W. Biochem. Pharmacol. 2006, 71, 957-967
8. Ostash, B.; Walker, S. Nat. Prod. Rep. 2010, 27, 1594-1617
9. Perlstein, D. L.; Zhang, Y.; Wang, T. S.; Kahne, D. E.; Walker, S. J. Am. Chem. Soc. 2007, 129, 12674-12675
10. Barrett, D.; Wang, T. S.; Yuan, Y.; Zhang, Y.; Kahne, D.; Walker, S. J. Biol. Chem. 2007, 282, 31964-31971
11. Yuan, Y.; Barrett, D.; Zhang, Y.; Kahne, D.; Sliz, P.; Walker, S. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 5348-5353
12. Wang, T. S.; Manning, S. A.; Walker, S.; Kahne, D. J. Am. Chem. Soc. 2008, 130, 14068-14069
13. Perlstein, D. L.; Wang, T. S.; Doud, E. H.; Kahne, D.; Walker, S. J. Am. Chem. Soc. 2010, 132, 48-49
14. Breyer, W. A.; Matthews, B. W. Protein Sci. 2001, 10, 1699-1711
15. May, J. F.; Splain, R. A.; Brotschi, C.; Kiessling, L. L. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 11851-11856
16. Schwartz, B.; Markwalder, J. A.; Seitz, S. P.; Wang, Y.; Stein, R. L. Biochemistry 2002, 41, 12552-12561
17. Chen, L.; Walker, D.; Sun, B.; Hu, Y.; Walker, S.; Kahne, D. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 5658-5663
18. Barrett, D.; Leimkuhler, C.; Chen, L.; Walker, D.; Kahne, D.; Walker, S. J. Bacteriol. 2005, 187, 2215-2217
19. Wodzinska, J.; Snell, K. D.; Rhomberg, A.; Sinskey, A. J.; Biemann, K.; Stubbe, J. J. Am. Chem. Soc. 1996, 118, 6319-6320
20. Yin, Y. W.; Steitz, T. A. Science 2002, 298, 1387-1395
21. Peng, L.; Kawagoe, Y.; Hogan, P.; Delmer, D. Science 2002, 295, 147-150
22. DeAngelis, P. L. J. Biol. Chem. 1999, 274, 26557-26562
23. Cartee, R. T.; Forsee, W. T.; Yother, J. J. Bacteriol. 2005, 187, 4470-4479
24. Zhang, Y.; Fechter, E. J.; Wang, T. S.; Barrett, D.; Walker, S.; Kahne, D. E. J. Am. Chem. Soc. 2007, 129, 3080-3081
25. Schindler, M.; Mirelman, D.; Schwarz, U. Eur. J. Biochem. 1976, 71, 131-134
26. Masibay, A. S.; Qasba, P. K. Proc. Natl. Acad. Sci. U.S.A. 1989, 86, 5733-5737
27. Roquemore, E. P.; Chou, T. Y.; Hart, G. W. Methods Enzymol. 1994, 230, 443-460
28. Boeggeman, E.; Ramakrishnan, B.; Kilgore, C.; Khidekel, N.; Hsieh-Wilson, L. C.; Simpson, J. T.; Qasba, P. K. Bioconjugate Chem. 2007, 18, 806-814
29. Khidekel, N.; Ficarro, S. B.; Clark, P. M.; Bryan, M. C.; Swaney, D. L.; Rexach, J. E.; Sun, Y. E.; Coon, J. J.; Peters, E. C.; Hsieh-Wilson, L. C. Nat. Chem. Biol. 2007, 3, 339-348
30. Men, H.; Park, P.; Ge, M.; Walker, S. J. Am. Chem. Soc. 1998, 120, 2484-2485
31. Ha, S.; Chang, E.; Lo, M.-C.; Men, H.; Park, P.; Ge, M.; Walker, S. J. Am. Chem. Soc. 1999, 121, 8415-8426
32. Ye, X.-Y.; Lo, M.-C.; Brunner, L.; Walker, D.; Kahne, D.; Walker, S. J. Am. Chem. Soc. 2001, 123, 3155-3156
33. Chen, L.; Men, H.; Ha, S.; Ye, X.-Y.; Brunner, L.; Hu, Y.; Walker, S. Biochemistry 2002, 41, 6824-6833
34. Anderson, J. S.; Matsuhashi, M.; Haskin, M. A.; Strominger, J. L. Proc. Natl. Acad. Sci. U.S.A. 1965, 53, 881-889
35. For descriptions of the constructs used, see the Supporting Information and the following reports: Barrett, D. S.; Chen, L.; Litterman, N. K.; Walker, S. Biochemistry 2004, 43, 12375-12381
36. Heaslet, H.; Shaw, B.; Mistry, A.; Miller, A. A. J. Struct. Biol. 2009, 167, 129-135
37. Paradis-Bleau, C.; Markovski, M.; Uehara, T.; Lupoli, T. J.; Walker, S.; Kahne, D. E.; Bernhardt, T. G. Cell 2010, 143, 1110-1120
38. For a review of non-template-dependent polymerase processes, see: Stubbe, J.; Tian, J.; He, A.; Sinskey, A. J.; Lawrence, A. G.; Liu, P. Annu. Rev. Biochem. 2005, 74, 433-480
39. Product lengths depend on the enzyme and are presumed to reflect processivity.
40. Tomsho, J. W.; Moran, R. G.; Coward, J. K. Biochemistry 2008, 47, 9040-9050
41. Jing, W.; DeAngelis, P. L. J. Biol. Chem. 2004, 279, 42345-42349