Cell transcytosing poly-arginine coated magnetic nanovector for safe and effective siRNA delivery

Biomaterials

Volumn 32, Issue 24, 2011, Pages 5717-5725

  Veiseh, Omid ^a   Kievit, Forrest M ^a   Mok, Hyejung ^a   Ayesh, Joseph ^b   Clark, Cassra ^b   Fang, Chen ^a   Leung, Matthew ^a   Arami, Hamed ^a   Park, James O ^c   Zhang, Miqin ^a  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cancer; Gene therapy; Iron oxide nanoparticle; MRI; SiRNA; Transcytosis

Indexed keywords

CANCER; IRON OXIDE NANOPARTICLE; MRI; SIRNA; TRANSCYTOSIS;

ARGININE; DISEASES; ETHYLENE; ETHYLENE GLYCOL; GENE THERAPY; GENETIC ENGINEERING; IRON OXIDES; MOLECULAR BIOLOGY; NANOPARTICLES; PLASTIC COATINGS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; RNA; TRANSMISSION ELECTRON MICROSCOPY;

CELLS;

MACROGOL; MAGNETIC NANOPARTICLE; MAGNETIC NANOVECTOR; NANOCARRIER; NANOCOATING; POLYARGININE; POLYETHYLENEIMINE; POLYLYSINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ANIMAL CELL; ARTICLE; BRAIN CANCER; BREAST CANCER; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL MIGRATION; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; DRUG STRUCTURE; ENDOCYTOSIS; FLUORESCENCE ANALYSIS; GENE SILENCING; GLIOMA CELL; HUMAN; HUMAN CELL; HYDRODYNAMICS BASED TRANSFECTION; MALE; NANOENGINEERING; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PARTICLE SIZE; PRIORITY JOURNAL; PROSTATE CANCER; RAT; RNA SEQUENCE; STRUCTURE ANALYSIS; SYNTHESIS; TRANSCYTOSIS; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; FERRIC COMPOUNDS; GENETIC VECTORS; HUMANS; MAGNETICS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PEPTIDES; RATS; RNA, SMALL INTERFERING; TRANSCYTOSIS; TRANSFECTION;

EID: 79957926113     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.04.039     Document Type: Article

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