Astaxanthin limits fish oil-related oxidative insult in the anterior forebrain of Wistar rats: Putative anxiolytic effects?

Pharmacology Biochemistry and Behavior

Volumn 99, Issue 3, 2011, Pages 349-355

  Mattei, Rita ^a   Polotow, Tatiana G ^b   Vardaris, Cristina V ^b   Guerra, Beatriz A ^b   Leite, José Roberto ^a   Otton, Rosemari ^b   Barros, Marcelo P ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSIDADE CRUZEIRO DO SUL   (Brazil)

Author keywords

Antioxidant; Anxiety; Astaxanthin; Brain; Carotenoid; Elevated plus maze; Fish oil; Omega 3

Indexed keywords

ASTAREAL A1010; ASTAXANTHIN; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; FISH OIL; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; IRON; MANGANESE SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR FOREBRAIN; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVITY; FOREBRAIN; LIPID OXIDATION; MALE; MONOAMINERGIC SYSTEM; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTIOXIDANTS; DRUG THERAPY, COMBINATION; FISH OILS; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PROSENCEPHALON; RATS; RATS, WISTAR; XANTHOPHYLLS;

ANIMALIA; RATTUS NORVEGICUS;

EID: 79957921043     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2011.05.009     Document Type: Article

References (47)

1. Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-6.
2. Appleton KM, Gunnell D, Peters TJ, Ness AR, Kessler D, Rogers PJ. No clear evidence of an association between plasma concentrations of n-3 long-chain polyunsaturated fatty acids and depressed mood in a non-clinical population. Prostaglandins Leukot Essent Fatty Acids 2008;78:337-42.
3. Barros MP, Pinto E, Colepicolo P, Pedersen M. Astaxanthin and peridinin inhibit oxidative damage in Fe(2+)-loaded liposomes: scavenging oxyradicals or changing membrane permeability? Biochem Biophys Res Commun 2001;288:225-32.
4. Bas O, Songur A, Sahin O, Mollaoglu H, Ozen OA, Yaman M, et al. The protective effect of fish n-3 fatty acids on cerebral ischemia in rat hippocampus. Neurochem Int 2007;50:548-54. (Pubitemid 46186606)
5. Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of "Antioxidant Power": the FRAP assay. Anal Biochem 1996;239:70-6.
6. Binienda ZK, Ali SF, Virmani A, Amato A, Salem N, Przybyla BD. Co-regulation of dopamine D1 receptor and uncoupling protein-2 expression in 3-nitropropionic acid-induced neurotoxicity: neuroprotective role of L-carnitine. Neurosci Lett 2006;410:62-5. (Pubitemid 44667258)
7. Bolin AP, Macedo RC, Marin DP, Barros MP, Otton R. Astaxanthin prevents in vitro autooxidative injury in human lymphocytes. Cell Biol Toxicol 2010;26:457-67.
8. Brewer KJ, Murphy Jr WR, Petersen JD. Synthesis and characterization of monometallic and bimetallic mixed-ligand complexes of iron(II) containing 2,2′-bipyrimidine or 2,3-bis(2-pyridyl)pyrazine. Inorg Chem 1987;26:3376-9.
9. Broadhurst CL, Wang Y, Crawford MA, Cunnane SC, Parkington JE, Schmidt WF. Brain-specific lipids from marine, lacustrine, or terrestrial food resources: potential impact on early African Homo sapiens. Comp Biochem Physiol B Biochem Mol Biol 2002;131:653-73. (Pubitemid 34266818)
10. Calabrese V, Scapagnini G, Giuffrida Stella AM, Bates TE, Clark JB. Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity. Neurochem Res 2001;26:739-64. (Pubitemid 32756837)
11. Calabrese V, Cornelius C, Dinkova-Kostova AT, Calabrese EJ, Mattson MP. Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal 2010;13:1763-811.
12. Cao D-H, Xu J-F, Xue R-H, Zheng W-F, Liu Z-L. Protective effect of chronic ethyl docosaehxaenoate administration on brain injury in ischemic gerbils. Pharmacol Biochem Behav 2004;79:651-9. (Pubitemid 39600605)
13. Carlberg I, Mannervik B. Glutathione reductase. Methods Enzymol 1985;113:484-90. (Pubitemid 16195819)
14. Choi HD, Kang HE, Yang SH, Lee MG, Shin WG. Pharmacokinetics and first-pass metabolism of astaxanthin in rats. Br J Nutr 2011;105:220-7.
15. Cunnane SC, Plourde M, Pifferi F, Bégin M, Féart C, Barberger-Gateau P. Fish, docosahexaenoic acid and Alzheimer's disease. Prog Lipid Res 2009;48: 239-56.
16. Davis LM, Rho JM, Sullivan PG. UCP-mediated free fatty acid uncoupling of isolated cortical mitochondria from fasted animals: correlations to dietary modulations. Epilepsia 2008;49:117-9.
17. Emsley R, Niehaus DJ, Oosthuizen PP, Koen L, Ascott-Evans B, Chiliza B, et al. Safety of the omega-3 fatty acid, eicosapentaenoic acid (EPA) in psychiatric patients: results from a randomized, placebo-controlled trial. Psychiatry Res 2008;161:284-91.
18. Ewing JF, Janero DR. Microplate superoxide dismutase assay employing a nonenzymatic superoxide generator. Anal Biochem 1995;232:243-8. (Pubitemid 26010266)
19. Floyd RA. Neuroinflammatory processes are important in neurodegenerative diseases: an hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development. Free Radic Biol Med 1999;26:1346-55. (Pubitemid 29262724)
20. Fraga CG, Leibovitz BE, Tappel AL. Lipid peroxidation measured as thiobarbituric acid-reactive substances in tissue slices: characterization and comparison with homogenates and microsomes. Free Radic Biol Med 1988;4:155-61. (Pubitemid 18052530)
21. Goodwin JF, Murphy B. The colorimetric determination of iron in biological material with reference to its measurement during chelation therapy. Clin Chem 1966;12:58-69.
22. Gorjão R, Azevedo-Martins AK, Rodrigues HG, Abdulkader F, Arcisio-Miranda M, Procopio J, et al. Comparative effects of DHA and EPA on cell function. Pharmacol Ther 2009;122:56-64.
23. Green P, Glozman S, Weiner L, Yavin E. Enhanced free radical scavenging and decreased lipid peroxidation in the rat fetal brain after treatment with ethyl docosahexaenoate. Biochim Biophys Acta 2001;1532:203-12. (Pubitemid 32706440)
24. Guerin M, Huntley ME, Olaizola M. Haematococcus astaxanthin: applications for human health and nutrition. Trends Biotechnol 2003;21:210-6. (Pubitemid 36515074)
25. Halliwell B. Oxidative stress and neurodegeneration: where are we now? J Neurochem 2006;97:1634-58.
26. Homi HM, Freitas JJ, Curi R, Velasco IT, Junior BA. Changes in superoxide dismutase and catalase activities of rat brain regions during early global transient ischemia/reperfusion. Neurosci Lett 2002;333:37-40. (Pubitemid 35223597)
27. Jicha GA, Markesbery WR. Omega-3 fatty acids: potential role in the management of early Alzheimer's disease. Clin Interv Aging 2010;5:45-61.
28. King VR, Huang WL, Dyall SC, Curran OE, Priestley JV, Michael-Titus AT. Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat. J Neurosci 2006;26:4672-80. (Pubitemid 44315368)
29. Komprda T, Zelenka J, Fajmonová E, Fialová M, Kladroba D. Arachidonic acid and long-chain n-3 polyunsaturated fatty acid contents in meat of selected poultry and fish species in relation to dietary fat sources. J Agric Food Chem 2005;53:6804-12. (Pubitemid 41260727)
30. +-induced mitochondrial dysfunction and ROS production in vivo and in vitro. Food Chem Toxicol 2011;49:271-80.
31. Liu X, Osawa T. Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food. Forum Nutr 2009;61:129-35.
32. 2-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo. Brain Res 2010;1360:40-8.
33. Mannervik B. Glutathione peroxidase. Methods Enzymol 1985;113:490-5. (Pubitemid 16195820)
34. Mattei R, Barros MP, Galvão SMP, Bechara EJH, Carlini ELA. Heteropteris aphrodisiaca O. Machado: effects of extract BST 0298 on the oxidative stress of young and old rat brains. Phytother Res 2001;15:604-7.
35. Murphy ME, Kehrer JP. Oxidation state of tissue thiol groups and content of protein carbonyl groups in chickens with inherited muscular dystrophy. Biochem J 1989;260:359-64. (Pubitemid 19151078)
36. Otton R, Marin DP, Bolin AP, Santos RC, Polotow TG, Sampaio SC, et al. Astaxanthin ameliorates the redox imbalance in lymphocytes of experimental diabetic rats. Chem Biol Interact 2010;186:306-15.
37. Palozza P, Krinsky NI. Astaxanthin and canthaxanthin are potent antioxidants in a membrane model. Arch Biochem Biophys 1992;297:291-5. (Pubitemid 23282883)
38. Park UJ, Lee YA, Won SM, Lee JH, Kang SH, Springer JE, et al. Blood-derived iron mediates free radical production and neuronal death in the hippocampal CA1 area following transient forebrain ischemia in rat. Acta Neuropathol 2011;121:459-73.
39. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. 6th ed. New York: Academic Press; 2008.
40. Peeters-Joris C, Vandevoorde AM, Baudhuin P. Subcellular localization of superoxide dismutase in rat liver. Biochem J 1975;150:31-9.
41. Pellow S, File SE. Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav 1986;24:524-9.
42. Rahman I, Kode A, Biswas SK. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat Protoc 2006;1:3159-65.
43. Shelton RC, Brown LL. Mechanisms of action in the treatment of anxiety. J Clin Psychiatry 2001;62:10-5. (Pubitemid 32578702)
44. Sienkiewicz-Jarosz H, Szyndler J, Członkowska AI, Siemiatkowski M, Maciejak P, Wisłowska A, et al. Rat behavior in two models of anxiety and brain [3 H]muscimol binding: pharmacological, correlation, and multifactor analysis. Behav Brain Res 2003;145:17-22. (Pubitemid 37188628)
45. Stahl W, Sies H. Bioactivity and protective effects of natural carotenoids. Biochim Biophys Acta 2005;1740:101-7. (Pubitemid 40798218)
46. Stookey LL. Ferrozine: a new spectrophotometric reagent for iron. Anal Chem 1970;42:779-81.
47. Van den Berg R, Haenen GRMM, Van den Berg H, Bast A. Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures. Food Chem 1999;66:511-7.