메뉴 건너뛰기




Volumn 25, Issue 6, 2011, Pages 2031-2039

Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions

Author keywords

Insulin; Liver; Vitamin D

Indexed keywords

FAT; GLUCOSE; KLOTHO PROTEIN; LEPTIN;

EID: 79957882571     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-167056     Document Type: Article
Times cited : (41)

References (39)
  • 1
    • 13844318061 scopus 로고    scopus 로고
    • Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice
    • DOI 10.1247/csf.29.91
    • Li, S. A., Watanabe, M., Yamada, H., Nagai, A., Kinuta, M., and Takei, K. (2004) Immunohistochemical localization of klotho protein in brain, kidney, and reproductive organs of mice. Cell Struct. Funct. 29, 91-99 (Pubitemid 40260033)
    • (2004) Cell Structure and Function , vol.29 , Issue.4 , pp. 91-99
    • Li, S.A.1    Watanabe, M.2    Yamada, H.3    Nagai, A.4    Kinuta, M.5    Takei, K.6
  • 3
    • 0036729991 scopus 로고    scopus 로고
    • Klotho: A fundamental regulator of aging
    • Nabeshima, Y. (2002) Klotho: a fundamental regulator of aging. Ageing Res. Rev. 1, 627-638
    • (2002) Ageing Res. Rev. , vol.1 , pp. 627-638
    • Nabeshima, Y.1
  • 4
    • 70350552306 scopus 로고    scopus 로고
    • Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model
    • Nakatani, T., Ohnishi, M., and Razzaque, M. S. (2009) Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model. FASEB J. 23, 3702-3711
    • (2009) FASEB J. , vol.23 , pp. 3702-3711
    • Nakatani, T.1    Ohnishi, M.2    Razzaque, M.S.3
  • 7
    • 67349229781 scopus 로고    scopus 로고
    • Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase
    • Ohnishi, M., Nakatani, T., Lanske, B., and Razzaque, M. S. (2009) Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase. Kidney Int. 75, 1166-1172
    • (2009) Kidney Int. , vol.75 , pp. 1166-1172
    • Ohnishi, M.1    Nakatani, T.2    Lanske, B.3    Razzaque, M.S.4
  • 8
    • 0031570346 scopus 로고    scopus 로고
    • The molecular basis of the obese mutation in ob2J mice
    • Moon, B. C., and Friedman, J. M. (1997) The molecular basis of the obese mutation in ob2J mice. Genomics 42, 152-156
    • (1997) Genomics , vol.42 , pp. 152-156
    • Moon, B.C.1    Friedman, J.M.2
  • 9
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman, J. M., and Halaas, J. L. (1998) Leptin and the regulation of body weight in mammals. Nature 395, 763-770
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 10
    • 0030847432 scopus 로고    scopus 로고
    • Acute stimulation of glucose metabolism in mice by leptin treatment
    • DOI 10.1038/38717
    • Kamohara, S., Burcelin, R., Halaas, J. L., Friedman, J. M., and Charron, M. J. (1997) Acute stimulation of glucose metabolism in mice by leptin treatment. Nature 389, 374-377 (Pubitemid 27415217)
    • (1997) Nature , vol.389 , Issue.6649 , pp. 374-377
    • Kamohara, S.1    Burcelin, R.2    Halaas, J.L.3    Friedman, J.M.4    Charron, M.J.5
  • 11
    • 77954451875 scopus 로고    scopus 로고
    • Development of high-fat-diet-induced obesity in female metallothionein-null mice
    • Sato, M., Kawakami, T., Kondoh, M., Takiguchi, M., Kadota, Y., Himeno, S., and Suzuki, S. (2010) Development of high-fat-diet-induced obesity in female metallothionein-null mice. FASEB J. 24, 2375-2384
    • (2010) FASEB J. , vol.24 , pp. 2375-2384
    • Sato, M.1    Kawakami, T.2    Kondoh, M.3    Takiguchi, M.4    Kadota, Y.5    Himeno, S.6    Suzuki, S.7
  • 12
    • 67649306717 scopus 로고    scopus 로고
    • Diet-induced obesity in female mice leads to peroxidized lipid accumulations and impairment of hippocampal neurogenesis during the early life of their offspring
    • Tozuka, Y., Wada, E., and Wada, K. (2009) Diet-induced obesity in female mice leads to peroxidized lipid accumulations and impairment of hippocampal neurogenesis during the early life of their offspring. FASEB J. 23, 1920-1934
    • (2009) FASEB J. , vol.23 , pp. 1920-1934
    • Tozuka, Y.1    Wada, E.2    Wada, K.3
  • 13
    • 77956637592 scopus 로고    scopus 로고
    • Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging
    • Ohnishi, M., and Razzaque, M. S. (2010) Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging. FASEB J. 24, 3562-3571
    • (2010) FASEB J. , vol.24 , pp. 3562-3571
    • Ohnishi, M.1    Razzaque, M.S.2
  • 14
    • 33751517092 scopus 로고    scopus 로고
    • Life-long suppression of growth hormone-insulin-like growth factor I activity in genetically altered rats could prevent age-related renal damage
    • DOI 10.1210/en.2006-0302
    • Zha, Y., Le, V. T., Higami, Y., Shimokawa, I., Taguchi, T., and Razzaque, M. S. (2006) Life-long suppression of growth hormone-insulin-like growth factor I activity in genetically altered rats could prevent age-related renal damage. Endocrinology 147, 5690-5698 (Pubitemid 44833485)
    • (2006) Endocrinology , vol.147 , Issue.12 , pp. 5690-5698
    • Zha, Y.1    Viet, T.L.2    Higami, Y.3    Shimokawa, I.4    Taguchi, T.5    Razzaque, M.S.6
  • 15
    • 33646238028 scopus 로고    scopus 로고
    • Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process
    • DOI 10.1096/fj.05-5432fje
    • Razzaque, M. S., Sitara, D., Taguchi, T., St-Arnaud, R., and Lanske, B. (2006) Premature ageing-like phenotype in fibroblast growth factor 23 null mice is a vitamin-D mediated process. FASEB J. 20, 720-722 (Pubitemid 46671193)
    • (2006) FASEB Journal , vol.20 , Issue.6 , pp. 720-722
    • Razzaque, M.S.1    Sitara, D.2    Taguchi, T.3    St-Arnaud, R.4    Lanske, B.5
  • 21
    • 78649741587 scopus 로고    scopus 로고
    • Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism
    • Rabot, S., Membrez, M., Bruneau, A., Gérard, P., Harach, T., Moser, M., Raymond, F., Mansourian, R., and Chou, C. J. (2010) Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism. FASEB J. 24, 4948-4959
    • (2010) FASEB J. , vol.24 , pp. 4948-4959
    • Rabot, S.1    Membrez, M.2    Bruneau, A.3    Gérard, P.4    Harach, T.5    Moser, M.6    Raymond, F.7    Mansourian, R.8    Chou, C.J.9
  • 23
    • 70350348267 scopus 로고    scopus 로고
    • The FGF23-Klotho axis: Endocrine regulation of phosphate homeostasis
    • Razzaque, M. S. (2009) The FGF23-Klotho axis: endocrine regulation of phosphate homeostasis. Nat. Rev. Endocrinol. 5, 611-619
    • (2009) Nat. Rev. Endocrinol. , vol.5 , pp. 611-619
    • Razzaque, M.S.1
  • 25
    • 0032746021 scopus 로고    scopus 로고
    • Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia
    • Kawaguchi, H., Manabe, N., Miyaura, C., Chikuda, H., Nakamura, K., and Kuro-o, M. (1999) Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia. J. Clin. Invest. 104, 229-237
    • (1999) J. Clin. Invest. , vol.104 , pp. 229-237
    • Kawaguchi, H.1    Manabe, N.2    Miyaura, C.3    Chikuda, H.4    Nakamura, K.5    Kuro-o, M.6
  • 26
    • 78650668099 scopus 로고    scopus 로고
    • Phosphate toxicity: New insights into an old problem
    • Razzaque, M. S. (2011) Phosphate toxicity: new insights into an old problem. Clin. Sci. (Lond.) 120, 91-97
    • (2011) Clin. Sci. (Lond.) , vol.120 , pp. 91-97
    • Razzaque, M.S.1
  • 27
    • 0035207072 scopus 로고    scopus 로고
    • Troglitazone improves endothelial function and augments renal klotho mRNA expression on Otsuka Long-Evans Tokushima Fatty (OLETF) rats with multiple atherogenic risk factors
    • DOI 10.1291/hypres.24.705
    • Yamagishi, T., Saito, Y., Nakamura, T., Takeda, S., Kanai, H., Sumino, H., Kuro-o, M., Nabeshima, Y., Kurabayashi, M., and Nagai, R. (2001) Troglitazone improves endothelial function and augments renal klotho mRNA expression in Otsuka Long-Evans Tokushima fatty (OLETF) rats with multiple atherogenic risk factors. Hypertens. Res. 24, 705-709 (Pubitemid 33133785)
    • (2001) Hypertension Research , vol.24 , Issue.6 , pp. 705-709
    • Yamagishi, T.1    Saito, Y.2    Nakamura, T.3    Takeda, S.-I.4    Kanai, H.5    Sumino, H.6    Kuro-O, M.7    Nabeshima, Y.-I.8    Kurabayashi, M.9    Nagai, R.10
  • 30
    • 77449126558 scopus 로고    scopus 로고
    • In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levels
    • Ohnishi, M., Nakatani, T., Lanske, B., and Razzaque, M. S. (2009) In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levels. Circ. Cardiovasc. Genet. 2, 583-590
    • (2009) Circ. Cardiovasc. Genet. , vol.2 , pp. 583-590
    • Ohnishi, M.1    Nakatani, T.2    Lanske, B.3    Razzaque, M.S.4
  • 31
    • 79952700577 scopus 로고    scopus 로고
    • The dualistic role of vitamin D in vascular calcifications
    • [E-pub ahead of print] doi: 10.1038/ki.2010.432
    • Razzaque, M. S. (2011) The dualistic role of vitamin D in vascular calcifications. [E-pub ahead of print] Kidney Int. doi: 10.1038/ki.2010.432
    • (2011) Kidney Int.
    • Razzaque, M.S.1
  • 32
    • 1442274634 scopus 로고    scopus 로고
    • 3-1alpha-Hydroxylase and -24-Hydroxylase in Leptin-Deficient, ob/ ob Mice
    • DOI 10.1210/en.2003-1010
    • Matsunuma, A., Kawane, T., Maeda, T., Hamada, S., and Horiuchi, N. (2004) Leptin corrects increased gene expression of renal 25-hydroxyvitamin D3-1 alpha-hydroxylase and -24-hydroxylase in leptin-deficient, ob/ob mice. Endocrinology 145, 1367-1375 (Pubitemid 38281021)
    • (2004) Endocrinology , vol.145 , Issue.3 , pp. 1367-1375
    • Matsunuma, A.1    Kawane, T.2    Maeda, T.3    Hamada, S.4    Horiuchi, N.5
  • 34
    • 0034130405 scopus 로고    scopus 로고
    • Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases
    • DOI 10.1007/s000180050038
    • Nagai, R., Saito, Y., Ohyama, Y., Aizawa, H., Suga, T., Nakamura, T., Kurabayashi, M., and Kuroo, M. (2000) Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases. Cell. Mol. Life Sci. 57, 738-746 (Pubitemid 30392032)
    • (2000) Cellular and Molecular Life Sciences , vol.57 , Issue.5 , pp. 738-746
    • Nagai, R.1    Saito, Y.2    Ohyama, Y.3    Aizawa, H.4    Suga, T.5    Nakamura, T.6    Kurabayashi, M.7    Kuro-O, M.8
  • 35
    • 0035906953 scopus 로고    scopus 로고
    • Upregulation of the klotho gene expression by thyroid hormone and during adipose differentiation in 3T3-L1 adipocytes
    • DOI 10.1016/S0024-3205(01)01092-X, PII S002432050101092X
    • Mizuno, I., Takahashi, Y., Okimura, Y., Kaji, H., and Chihara, K. (2001) Upregulation of the klotho gene expression by thyroid hormone and during adipose differentiation in 3T3-L1 adipocytes. Life Sci. 68, 2917-2923 (Pubitemid 32453259)
    • (2001) Life Sciences , vol.68 , Issue.26 , pp. 2917-2923
    • Mizuno, I.1    Takahashi, Y.2    Yasuhiko, O.3    Kaji, H.4    Chihara, K.5
  • 36
    • 79954490756 scopus 로고    scopus 로고
    • Osteo-renal regulation of systemic phosphate metabolism
    • [E-pub ahead of print] doi: 10.1002/iub.437
    • Razzaque, M. S. (2011) Osteo-renal regulation of systemic phosphate metabolism. [E-pub ahead of print] IUBMB Life doi: 10.1002/iub.437
    • (2011) IUBMB Life
    • Razzaque, M.S.1
  • 38
    • 65649129465 scopus 로고    scopus 로고
    • FGF23-mediated regulation of systemic phosphate homeostasis: Is klotho an essential player?
    • Razzaque, M. S. (2009) FGF23-mediated regulation of systemic phosphate homeostasis: is klotho an essential player? Am. J. Physiol. Renal Physiol. 296, F470-F476
    • (2009) Am. J. Physiol. Renal Physiol. , vol.296
    • Razzaque, M.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.