TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet

FASEB Journal

Volumn 24, Issue 9, 2010, Pages 3451-3461

  Cioffi, Federica ^a   Zambad, Shitalkumar P ^b   Chhipa, Laxmikant ^b   Senese, Rosalba ^a   Busiello, Rosa Anna ^d   Tuli, Davinder ^b   Munshi, Siralee ^b   Moreno, Maria ^e   Lombardi, Assunta ^d   Gupta, Ramesh C ^b   Chauthaiwale, Vijay ^c   Dutt, Chaitanya ^b   De Lange, Pieter ^a   Silvestri, Elena ^e   Lanni, Antonia ^a   Goglia, Fernando ^e  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Torrent Pharmaceuticals Ltd   (India)

^c DR REDDY'S LABORATORIES LTD   (India)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e UNIVERSITY OF SANNIO   (Italy)

Author keywords

Hepatic steatosis; Mitochondria; Thyroid hormones

Indexed keywords

3 [4 (7 HYDROXY 6 METHYLINDAN 4 YLMETHYL) 3,5 DIMETHYLPYRAZOLYL]PROPIONIC ACID; ACETYL COENZYME A CARBOXYLASE; ADENYLATE KINASE; CARNITINE PALMITOYLTRANSFERASE; CHOLESTEROL; IODOTHYRONINE; MALONYL COENZYME A; SIRTUIN 1; TRC 150094; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; COMORBIDITY; CONTROLLED STUDY; ENERGY EXPENDITURE; EPIDEMIC; FAT INTAKE; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; LIFESTYLE; LIVER MITOCHONDRION; MALE; NONHUMAN; OBESITY; OVERNUTRITION; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; TIBIALIS ANTERIOR MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOSITY; ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; CARNITINE O-PALMITOYLTRANSFERASE; DIETARY FATS; EATING; ENERGY METABOLISM; FATTY ACIDS; MALE; OBESITY; OXIDATION-REDUCTION; RATS; RATS, WISTAR; SIRTUIN 1; THYRONINES; THYROTROPIN; THYROXINE; TRIGLYCERIDES; TRIIODOTHYRONINE;

RATTUS;

EID: 77956620361     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-157115     Document Type: Article

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