Evaluation of the genotoxic and antigenotoxic potential of Melissa officinalis in mice

Genetics and Molecular Biology

Volumn 34, Issue 2, 2011, Pages 290-297

  de Carvalho, Natália Cassettari ^a   Corrêa Angeloni, Maria Júlia Frydberg ^a   Leffa, Daniela Dimer ^a   Moreira, Jeverson ^a   Nicolau, Vanessa ^a   de Aguiar Amaral, Patrícia ^a   Rossatto, Ângela Erna ^a   de Andrade, Vanessa Moraes ^a  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

Author keywords

Antigenotoxicity; Comet assay; Genotoxicity; Melissa officinalis; Micronucleus test

Indexed keywords

ALCOHOL; MELISSA OFFICINALIS EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG MEGADOSE; DRUG SCREENING; GENOTOXICITY; MALE; MELISSA OFFICINALIS; MOUSE; MUTAGENICITY; NONHUMAN; TREATMENT DURATION;

CITRUS LIMON; LAMIACEAE; MELISSA; MELISSA OFFICINALIS; MUS;

EID: 79957879857     PISSN: 14154757     EISSN: 16784685     Source Type: Journal    
DOI: 10.1590/S1415-47572011000200021     Document Type: Article

References (47)

1. Atoui AK, Mansouri A, Boskou G and Kefalas P (2005) Tea and herbal infusions: Their antioxidant activity and phenolic profile. Food Chem 89:27-36.
2. Azevedo L, Gomes JC, Stringheta PC, Gontijo AMMC, Padovani CR, Ribeiro LR and Salvadori DMF (2003) Black bean (Phaseolus vulgaris L.) as a protective agent against DNA damage in mice. Food Chem Toxicol 41:1671-1676.
3. Azevedo L, Lima PLA, Gomes JC, Stringheta PC, Ribeiro DA and Salvadori DMF (2007) Differential response related to genotoxicity between eggplant (Solanum melanogena) skin aqueous extract and its main purified anthocyanin (del-phinidin) in vivo. Food Chem Toxicol 45:852-858.
4. Berhow M, Wagner E, Vaughn S and Plewa M (2000) Characterization and antimutagenic activity of soybean saponins. Mu-tat Res 448:11-22.
5. Boiteux S and Guillet M (2004) Abasic sites in DNA: Repair and biological consequences in Saccharomyces cerevisae. DNA Repair 3:1-12.
6. Bresolin S and Vargas VMF (1993) Mutagenic potencies of medicinal plants screened in the Ames test. Phytother Res 7:260-262.
7. Canadanovic-Brunet J, Cetkovic G, Djilas S, Tumbas V, Bogda-novic G, Mandic A, Markov S, Cvetkovic D and Cana-danovic V (2008) Radical scavenging, antibacterial, and antiproliferative activities of Melissa officinalis (L.) extracts. J Med Food 11:133-143.
8. Carnat AP, Carnat A, Fraisse D and Lamaison JL (1998) The aromatic and polyphenolic composition of lemon balm (Melissa officinalis L. subsp. officinalis) tea. Pharm Acta Helv 72:301-305.
9. Collins A, Dusinska M, Franklin M, Somorosyska M, Petroyska H, Duthie S, Fillion L, Panyotidis M, Raslová K and Vau-ghan N (1997) Comet assay in human biomonitoring studies: Reliability, validation, and applications. Environ Mol Mutagen 30:139-146.
10. Czeczot H and Kusztelak J (1993) A study of the genotoxic potential of flavonoids using short-term bacterial assays. Acta Biochim Pol 40:549-554.
11. Dastmalchi K, Dorman HJD, Oinonen PP, Darwis Y, Laakso I and Hiltunen R (2008) Chemical composition and in vitro antio-xidative activity of a lemon balm (Melissa officinalis L.) extract. LWT - Food Sci Technol 41:391-400.
12. Doostdar H, Burke D and Mayer RT (2000) Bioflavonoids: Selective substrates and inhibitors for cytochrome P450 CYP1A andCYP1B1. Toxicology 144:31-38.
13. Edenharder R, Sager JW, Glatt H, Muckel E and Platt KL (2002) Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2 acetylaminofluoreno and 2-amino-1-methyl-6-phenylimidazol [4,5-6] pyridine (PhIP) in metabolically competent V79 cells. Mutat Res 521:57-72.
14. Farmacopéia Brasileira (2001) Farmacopéia Brasileira. 4th edition. Atheneu, São Paulo, 294 pp.
15. Fernandes JBF and Vargas VMF (2003) Mutagenic and anti-mutagenic potential of the medicinal plants M. laevigata and C. xanthocarpa. Phytother Res 17:269-273.
16. Franke SIR, Pra D, Erdtmann B, Henriques JAP and da Silva J (2005) Influence of orange juice over the genotoxicity induced by alkylating agents: An in vivo analysis. Mutagenesis 20:279-283.
17. Furtado MA, Almeida LCF, Furtado RA, Cunha WR and Tavares DC (2008) Antimutagenicity of rosmarinic acid in Swiss mice evaluated by the micronucleus assay. Mutat Res 657:150-154.
18. Furtado RA, Araújo FRR, Resende FA, Cunha WR and Tavares DC (2010) Protective effect of rosmarinic acido on V79 cells evaluated by the micronucleus and comet assays. J Appl Toxicol 30:254-259.
19. Geetha T, Malhotra V, Chopra K and Kaur IP (2005) Anti-mutagenic and antioxidant/prooxidant activity of Quercetin. Ind J Exp Biol 43:61-67.
20. Gomes-Carneiro MR, Dias DMM, De Oliveira ACAX and Paum-gartten FJR (2005) Evaluation of mutagenic and antimuta-genic activities of a-bisabolol in the Salmonella/microsome assay. Mutat Res 585:105-112.
21. Guginski G, Luiz AP, Silva MS, Massaro M, Martins DF, Chaves J, Mattos RW, Silveira D, Ferreira VMM, Calixto JB, et al. (2009) Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice. Pharmacol Biochem Behav 93:10-16.
22. Harborn JB (1998) Phenolic compounds. In: Harborne JB (ed) Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. Chapman & Hall, London, pp 40-106.
23. Hernández-Ceruelos A, Madrigal-Bujaidadar E and De La Cruz C (2002) Inhibitory effect of chamomile essential oil on the sister chromatid exchanges by daunorubicin and methyl methanesulfonate in mouse bone marrow. Toxicol Lett 135:103-110.
24. Herodez SS, Hadolin M, Skerget M and Zeljko K (2003) Solvent extraction study of antioxidants from balm (Melissa officinalis L.) leaves. Food Chem 80:275-282.
25. Horvathova E, Slamenova D, Hlincikova L, Mandal TK, Ga-belova A and Collins AR (1998) The nature and origin of DNA single-strand breaks determined with the comet assay. Mutat Res 409:163-171.
26. Ivanova D, Gerova D, Chervenkov T and Yankova T (2005) Polyphenols and antioxidant capacity of Bulgarian medicinal plants. J Ethnopharmacol 96:145-150.
27. Katalinic V, Milos M, Kulisic T and Jukic M (2006) Screening of 70 medicinal plant extracts for antioxidant capacity and total phenols. Food Chem 94:550-557.
28. Kelly C, Jewell C and O'Brien NM (2003) The effect of dietary supplementation with the citrus limonoids, limonin and no-milin on xenobiotic-metabolizing enzymes in the liver and small intestine of the rat. Nutr Res 23:681-690.
29. Lima PLA, Delmanto RD, Sugui MM, Eira AF, Salvadori DMF, Speit G and Ribeiro LR (2001) Letinula edodes (Berk.) Pegler (Shiitake) modulates genotoxic and mutagenic effects induced by alkylating agents in vivo. Mutat Res 496:23-32.
30. Mavournin KH, Blakey DH, Cimino MC, Salamone MF and Heddle J (1990) The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res 232:29-80.
31. Mimica-Dukic N, Bozin B, Socovik M and Simin N (2004) Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiacea) essential oil. J Agric Food Chem 52:2485-2489.
32. Müzell DP (2006) Propriedades biológicas de extratos de Melissa officinalis L. (lamiaceae) em ratos wistar. Dissertação de Mestrado em Biologia Celular e Molecular, Faculdade de Biociências da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, 70 pp.
33. Patel D, Shukla S and Gupta S (2007) Apigenin and cancer chemoprevention: Progress, potential and promise. Int J Oncol 30:233-245.
34. Pereira P, Tysca D, Oliveira P, Da Silva-Brum LF, Picada JN and Ardenghi P (2005) Neurobehavioral and genotoxic aspects of rosmarinic acid. Pharmacol Res 52:199-203.
35. Pereira RP, Fachineto R, Prestes AS, Puntel RL, Boschetti TK, Athayde ML, Büerguer ME, Morel AF, Morsch VM and Rocha JBT (2009) Antioxidant effects of different extracts from Melissa officinalis, Matricaria recutita and Cymbopogon citratus. Neurochem Res 34:973-983.
36. Pérez-Pérez EM, Rodrígez-Malaver AJ, Padilla N, Medina-Ra-mírez G and Dávila J (2006) Antioxidant capacity of crude extracts from clones of banana and plane species. J Med Food 9:517-523.
37. Sá-Ferreira ICF and Vargas VMF (1999) Mutagenicity of medicinal plant extracts in Salmonella/microsome assay. Phytother Res 13:397-400.
38. Salah SM and Jäger AK (2005) Screening of traditionally used Lebanese herbs for neurological activities. J Ethnophar-macol 97:145-149.
39. Singh NP, McCoy MT, Tice RR and Schneider EL (1988) A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191.
40. Souza AC, Alviano DS, Alves PB, Alviano CS and Gattass CR (2004) Melissa officinalis L. essential oil: Antitumoral and antioxidant activities. J Pharm Pharmacol 56:677-681.
41. Surh Y and Fergunson LR (2003) Dietary and medicinal anti-mutagens and anticarcinogens: Molecular mechanisms and chemopreventive potential - Highlights of a symposium. Mutat Res 485:1-8.
42. Szaefer H, Cichocki M, Brauze D and Baer-Dubowska W (2004) Alteration in phase I and II enzyme activities and polycyclic aromatic hydrocarbons-DNA adduct formation by plant phenolics in mouse epidermis. Nutr Cancer 48:70-77.
43. Tovart RT (2009) Clinical approach to clinical herbal toxicity. Sem Diagn Pathol 26:28-37.
44. Villela IV, Oliveira IMde, Silva J da and Henriques JAP (2006) DNA damage and repair in haemolymph cells of golden mussel (Limnoperna fortunei) exposed to environmental contaminants. Mutat Res 605:78-86.
45. Wagner H and Bladt S (2009) Plant Drug Analysis: A Thin Layer Chromatography Atlas. 2nd edition. Springer, Heidelberg, 384 pp.
46. Waters MD, Brady AL, Stack HF and Brockman HE (1990) Antimutagenicity profiles for some model compounds. Mu-tat Res 238:57-85.
47. World Cancer Research Fund (2008) Food, nutrition, and the prevention of cancer: A global perspective. Nutrition 24:393-398.