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Volumn 43, Issue 1, 2005, Pages 61-67

Antimutagenic and antioxidant/prooxidant activity of quercetin

Author keywords

Ames test; Antimutagenicity; Antioxidant activity; Ascorbic acid; Quercetin

Indexed keywords

DEOXIDANTS; FREE RADICALS; HYDROGEN PEROXIDE; MUTAGENESIS; ORGANIC ACIDS; OXIDATION; SCAVENGING;

EID: 11444251181     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (71)

References (37)
  • 1
    • 0028068186 scopus 로고
    • Free radical, antioxidant and human disease: Curiosity, cause or consequence?
    • Halliwell B, Free radical, antioxidant and human disease: curiosity, cause or consequence? Lancet, 344 (1994) 721.
    • (1994) Lancet , vol.344 , pp. 721
    • Halliwell, B.1
  • 3
    • 0027742757 scopus 로고
    • Inhibitory effects of flavonoids on xanthine oxidase
    • Chang W S, Lee Y J, Lu F J & Chiang H C, Inhibitory effects of flavonoids on xanthine oxidase. Anticancer Res, 13 (1993) 2165.
    • (1993) Anticancer Res , vol.13 , pp. 2165
    • Chang, W.S.1    Lee, Y.J.2    Lu, F.J.3    Chiang, H.C.4
  • 5
    • 0024364268 scopus 로고
    • Chelating and free radical scavenging mechanism of inhibitory action of rutin and quercetin in lipid peroxidation
    • Afanas'ev I B, Dorozhki A I, Brodskii A V, Kostyuk V A & Potapovitch A I, Chelating and free radical scavenging mechanism of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem Pharmacol, 38 (1989) 1763.
    • (1989) Biochem Pharmacol , vol.38 , pp. 1763
    • Afanas'ev, I.B.1    Dorozhki, A.I.2    Brodskii, A.V.3    Kostyuk, V.A.4    Potapovitch, A.I.5
  • 6
    • 0028208715 scopus 로고
    • Inhibition of mitochondrial respiration and cyanide-stimulated generation of ROS by selective flavonoids
    • Hodnick W F, Duval D L & Pardini R S, Inhibition of mitochondrial respiration and cyanide-stimulated generation of ROS by selective flavonoids. Biochem Pharmcol, 47 (1994) 573.
    • (1994) Biochem Pharmcol , vol.47 , pp. 573
    • Hodnick, W.F.1    Duval, D.L.2    Pardini, R.S.3
  • 7
    • 0000820622 scopus 로고
    • A new Salmonella tester strain (TA-102) with AT-base pair at the site of mutation detects oxidative mutagen
    • Levin D E, Hollstein M, Christman M F, Schwiers E A & Ames B N, A new Salmonella tester strain (TA-102) with AT-base pair at the site of mutation detects oxidative mutagen. Proc Natl Acad Sci, 79 (1982) 7445.
    • (1982) Proc Natl Acad Sci , vol.79 , pp. 7445
    • Levin, D.E.1    Hollstein, M.2    Christman, M.F.3    Schwiers, E.A.4    Ames, B.N.5
  • 8
    • 0034633899 scopus 로고    scopus 로고
    • Sesamol exhibits antimutagenic activity against oxygen species mediated mutagenicity
    • Kaur I P & Saini A, Sesamol exhibits antimutagenic activity against oxygen species mediated mutagenicity. Mutat Res, 470 (2000) 71.
    • (2000) Mutat Res , vol.470 , pp. 71
    • Kaur, I.P.1    Saini, A.2
  • 9
    • 0027476039 scopus 로고
    • Ascorbic acid-enhanced antiproliferative effect of flavonoid on squamous cell carcinoma in vitro
    • Kandaswami C, Perkins E, Soloniuk D S, Drzewiecki E &. Middleton F, Ascorbic acid-enhanced antiproliferative effect of flavonoid on squamous cell carcinoma in vitro. Anti-Cancer Drugs, 4 (1993) 91.
    • (1993) Anti-Cancer Drugs , vol.4 , pp. 91
    • Kandaswami, C.1    Perkins, E.2    Soloniuk, D.S.3    Drzewiecki, E.4    Middleton, F.5
  • 10
    • 0020533372 scopus 로고
    • Revised methods for Salmonella mutagenicity test
    • Maron D M & Ames B N, Revised methods for Salmonella mutagenicity test. Mutat Res, 113 (1983) 173.
    • (1983) Mutat Res , vol.113 , pp. 173
    • Maron, D.M.1    Ames, B.N.2
  • 12
    • 0017804313 scopus 로고
    • Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase
    • Kono Y, Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys, 186 (1978) 189.
    • (1978) Arch Biochem Biophys , vol.186 , pp. 189
    • Kono, Y.1
  • 15
    • 0025020674 scopus 로고
    • Oxygen radical scavenging activity of curcumin
    • Kuchandy E & Rao M N A, Oxygen radical scavenging activity of curcumin. Int J Pharm, 58 (1990) 237.
    • (1990) Int J Pharm , vol.58 , pp. 237
    • Kuchandy, E.1    Rao, M.N.A.2
  • 17
    • 0023607808 scopus 로고
    • Pro-oxidant activation of ocular reductants.1. Copper and riboflavin stimulate ascorbate oxidation causing lens epithelial cytotoxicity in vitro
    • Wolff S P, Wang G M & Spector A, Pro-oxidant activation of ocular reductants.1. Copper and riboflavin stimulate ascorbate oxidation causing lens epithelial cytotoxicity in vitro. Exp Eye Res, 45 (1987) 777.
    • (1987) Exp Eye Res , vol.45 , pp. 777
    • Wolff, S.P.1    Wang, G.M.2    Spector, A.3
  • 19
    • 0032870923 scopus 로고    scopus 로고
    • Interaction of hydrated electron with dietary flavonoids and phenolic acids: Rate constants and transient spectra studied by pulse radiolysis
    • Cai Z, Li X & Katsumura Y, Interaction of hydrated electron with dietary flavonoids and phenolic acids: Rate constants and transient spectra studied by pulse radiolysis. Free Radic Biol Med, 27 (1999) 822.
    • (1999) Free Radic Biol Med , vol.27 , pp. 822
    • Cai, Z.1    Li, X.2    Katsumura, Y.3
  • 20
    • 0028932155 scopus 로고
    • Ion forming processes on 248 nm laser excitation of uracil and methyl-monosubstituted uracils: A time resolved transient conductivity study in aqueous solutions
    • Goerner H & Schulte-Frohlinde D, Ion forming processes on 248 nm laser excitation of uracil and methyl-monosubstituted uracils: A time resolved transient conductivity study in aqueous solutions. Radiat Phys Chem, 45 (1995) 677.
    • (1995) Radiat Phys Chem , vol.45 , pp. 677
    • Goerner, H.1    Schulte-Frohlinde, D.2
  • 21
    • 0011769715 scopus 로고    scopus 로고
    • Electron and hole transfer within DNA and its hydration layer
    • Sevilla M D, Becker D & Razskazovskii Y, Electron and hole transfer within DNA and its hydration layer. Neukeonika, 42 (1997) 283.
    • (1997) Neukeonika , vol.42 , pp. 283
    • Sevilla, M.D.1    Becker, D.2    Razskazovskii, Y.3
  • 22
    • 0025175962 scopus 로고
    • Identification of ultimate DNA damaging oxygen species
    • Epe B, Hegler J & Wold D, Identification of ultimate DNA damaging oxygen species. Environ Health Perspect, 88 (1990) 111.
    • (1990) Environ Health Perspect , vol.88 , pp. 111
    • Epe, B.1    Hegler, J.2    Wold, D.3
  • 23
    • 0023645563 scopus 로고
    • Generation of free radicals from organic hydroperoxide tumor promoters in isolated mouse keratinocytes
    • Taffe B G, Takahashi N, Kensler T W & Mason R P, Generation of free radicals from organic hydroperoxide tumor promoters in isolated mouse keratinocytes. J Biol Chem, 262 (1987) 12143.
    • (1987) J Biol Chem , vol.262 , pp. 12143
    • Taffe, B.G.1    Takahashi, N.2    Kensler, T.W.3    Mason, R.P.4
  • 24
    • 0025004502 scopus 로고
    • Flavonoids as antioxidants: Determination of radical-scavenging efficiencies
    • Bors W, Heller W, Michel C & Saran M, Flavonoids as antioxidants: Determination of radical-scavenging efficiencies. Method Enzymol, 186 (1990) 343.
    • (1990) Method Enzymol , vol.186 , pp. 343
    • Bors, W.1    Heller, W.2    Michel, C.3    Saran, M.4
  • 25
    • 0033593225 scopus 로고    scopus 로고
    • Activation of stress signaling pathways by the end product of lipid peroxidation- 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production
    • Uchida K, Shiraishi M, Naito Y, Torii Y, Nakamura Y & Osawa T, Activation of stress signaling pathways by the end product of lipid peroxidation- 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J Biol Chem, 274 (1999) 2234.
    • (1999) J Biol Chem , vol.274 , pp. 2234
    • Uchida, K.1    Shiraishi, M.2    Naito, Y.3    Torii, Y.4    Nakamura, Y.5    Osawa, T.6
  • 26
    • 0027504262 scopus 로고
    • Genotoxic properties of 4-hydroxyalkenals and analogous aldehydes
    • Eckl P M, Ortner A & Esterbauer H, Genotoxic properties of 4-hydroxyalkenals and analogous aldehydes. Mutat Res, 290 (1993) 183.
    • (1993) Mutat Res , vol.290 , pp. 183
    • Eckl, P.M.1    Ortner, A.2    Esterbauer, H.3
  • 27
    • 0037685148 scopus 로고    scopus 로고
    • Ability of antioxidants to prevent oxidative mutations in Salmonella typhimurium TA 102
    • Grey C E & Adlercreutz P, Ability of antioxidants to prevent oxidative mutations in Salmonella typhimurium TA 102. Mutat Res, 527 (2003) 27.
    • (2003) Mutat Res , vol.527 , pp. 27
    • Grey, C.E.1    Adlercreutz, P.2
  • 29
    • 0025237558 scopus 로고
    • Metabolic activation of natural phenols into selective oxygen burst against human neutrophils
    • Simons J M, Hart B A, Chang J V, Dijk H V & Labadie R P, Metabolic activation of natural phenols into selective oxygen burst against human neutrophils. Free Radic Biol Med, 8 (1990) 251.
    • (1990) Free Radic Biol Med , vol.8 , pp. 251
    • Simons, J.M.1    Hart, B.A.2    Chang, J.V.3    Dijk, H.V.4    Labadie, R.P.5
  • 30
    • 0345148810 scopus 로고    scopus 로고
    • Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product
    • Metodiewa D, Jaiswal A K, Cenas N, Dickancaite E & Aguilar J S, Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product. Free Rad Biol Med, 26 (1999) 107.
    • (1999) Free Rad Biol Med , vol.26 , pp. 107
    • Metodiewa, D.1    Jaiswal, A.K.2    Cenas, N.3    Dickancaite, E.4    Aguilar, J.S.5
  • 32
    • 0033795879 scopus 로고    scopus 로고
    • Potential health impacts of excessive flavonoid intake
    • Skibola C F & Smith M T, Potential health impacts of excessive flavonoid intake. Free Rad Biol Med, 29 (2000) 375.
    • (2000) Free Rad Biol Med , vol.29 , pp. 375
    • Skibola, C.F.1    Smith, M.T.2
  • 34
    • 0030010582 scopus 로고    scopus 로고
    • Pro-oxidant activity of flavonoids: Effects on glutathione S-transferase in isolated rat liver nuclei
    • Sahu S C & Gray G C, Pro-oxidant activity of flavonoids: Effects on glutathione S-transferase in isolated rat liver nuclei. Cancer Lett, 104 (1996) 193.
    • (1996) Cancer Lett , vol.104 , pp. 193
    • Sahu, S.C.1    Gray, G.C.2
  • 35
    • 0030044435 scopus 로고    scopus 로고
    • Antioxidant defences against reactive oxygen species causing genetic and other damage
    • Anderson D, Antioxidant defences against reactive oxygen species causing genetic and other damage. Mutat Res, 350 (1996) 103.
    • (1996) Mutat Res , vol.350 , pp. 103
    • Anderson, D.1
  • 36
    • 0031038440 scopus 로고    scopus 로고
    • Quercetin protects cutaneous-associated cell types including sensory neuronsfrom oxidative stress induced by GSH-depletion: Cooperative effect of ascorbic acid
    • Skaper S D, Fabris M, Ferrari V, Carbonare M D & Leon A, Quercetin protects cutaneous-associated cell types including sensory neuronsfrom oxidative stress induced by GSH-depletion: Cooperative effect of ascorbic acid. Free Radic Biol Med, 22 (1997) 669.
    • (1997) Free Radic Biol Med , vol.22 , pp. 669
    • Skaper, S.D.1    Fabris, M.2    Ferrari, V.3    Carbonare, M.D.4    Leon, A.5
  • 37
    • 0034665067 scopus 로고    scopus 로고
    • Interaction of the antioxidant flavonoid quercetin with planar lipid bilayers
    • Movileanu L, Interaction of the antioxidant flavonoid quercetin with planar lipid bilayers. Int J Pharm, 205 (2000) 135.
    • (2000) Int J Pharm , vol.205 , pp. 135
    • Movileanu, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.