Molecular basis of proton uptake in single and double mutants of cytochrome c oxidase

Journal of Physics Condensed Matter

Volumn 23, Issue 23, 2011, Pages

  Henry, Rowan M ^a,b   Caplan, David ^a,b   Fadda, Elisa ^c   Pomès, Régis ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ASPARTIC ACIDS; CARBOXYLATE GROUPS; CHANNEL ENTRANCES; CONFORMATIONAL ISOMERIZATION; CYTOCHROME C OXIDASE; D-CHANNEL; DIOXYGENS; DOUBLE MUTANTS; ELECTROSTATIC CALCULATIONS; ELECTROSTATIC CONTROL; ELECTROSTATIC REPULSION; INNER MEMBRANES; MOLECULAR BASIS; MOLECULAR DYNAMICS SIMULATIONS; OXYGEN CHEMISTRY; OXYGEN REDUCTION; POTENTIAL OF MEAN FORCE; PROTON MOVEMENTS; PROTON UPTAKE; PROTON-PUMPING; RESPIRATORY CHAINS; ROTAMERS; SIDE-CHAINS; SINGLE MUTANT; SINGLE-POINT MUTATION; SPHAEROIDES; STRUCTURAL FLUCTUATIONS; WILD TYPES;

AMINO ACIDS; CARBOXYLATION; CONFORMATIONS; ELECTROLYTIC REDUCTION; ELECTROSTATIC FORCE; ENZYME ACTIVITY; ISOMERIZATION; ISOMERS; MOLECULAR DYNAMICS; MOLECULAR OXYGEN; PUMPS; RESTORATION; VEHICULAR TUNNELS;

PROTONS;

CYTOCHROME C OXIDASE; MUTANT PROTEIN; PROTON;

ARTICLE; CHEMISTRY; ENZYMOLOGY; GENETICS; ISOMERISM; METABOLISM; MOLECULAR DYNAMICS; POINT MUTATION; PROTEIN CONFORMATION; RHODOBACTER SPHAEROIDES; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; ELECTRON TRANSPORT COMPLEX IV; ISOMERISM; MOLECULAR DYNAMICS SIMULATION; MUTANT PROTEINS; POINT MUTATION; PROTEIN CONFORMATION; PROTONS; RHODOBACTER SPHAEROIDES;

EID: 79957871568     PISSN: 09538984     EISSN: 1361648X     Source Type: Journal    
DOI: 10.1088/0953-8984/23/23/234102     Document Type: Article

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