Decoupling mutations in the D-Channel of the aa 3-Type cytochrome c oxidase from rhodobacter sphaeroides suggest that a continuous hydrogen-bonded chain of waters is essential for proton pumping

Biochemistry

Volumn 49, Issue 21, 2010, Pages 4476-4482

  Zhu, Jiapeng ^a   Han, Huazhi ^a   Pawate, Ashtamurthy ^a   Gennis, Robert B ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CATALYTIC SITES; CATALYTIC TURNOVER; CYTOCHROME C OXIDASE; D-CHANNEL; DATA DISPLAY; HYDROGEN-BONDED CHAINS; HYDROPHOBIC RESIDUES; INPUT CHANNELS; OXIDASE ACTIVITY; PROTON DELIVERY; PROTON LOADING; PROTON PUMP; PROTON-PUMPING; RHODOBACTER SPHAEROIDES; TIME WINDOWS; TURNOVER RATE; WATER FORMATION; WATER MOLECULE; WILD TYPES;

ENZYME ACTIVITY; ENZYMES; FUZZY CONTROL; MOLECULES; PUMPS; STOICHIOMETRY;

PROTONS;

BACTERIAL ENZYME; CYTOCHROME C OXIDASE; OXYGEN; PROTON; PROTON PUMP; WATER;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; HYDROGEN BOND; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RHODOBACTER SPHAEROIDES; STOICHIOMETRY; SUBSTITUTION REACTION; TURNOVER TIME; WILD TYPE;

BINDING SITES; ELECTRON TRANSPORT COMPLEX IV; HYDROGEN BONDING; MUTATION; PROTON PUMPS; PROTONS; RHODOBACTER SPHAEROIDES; WATER;

RHODOBACTER SPHAEROIDES;

EID: 77952825869     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100344x     Document Type: Article

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